Transcriptional regulation of CD4 gene expression by T cell factor-1/β-catenin pathway

Journal of Immunology

Volumn 176, Issue 8, 2006, Pages 4880-4887

  Huang, Zhaofeng ^a   Xie, Huimin ^a   Ioannidis, Vassilio ^b   Held, Werner ^b   Clevers, Hans ^c   Sadim, Maureen S ^a,d   Sun, Zuoming ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c HUBRECHT INSTITUTE   (Netherlands)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; PROTEIN BCL 2; PROTEIN BCL XL; T CELL FACTOR 1 PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BINDING SITE; CD4+ CD8+ THYMOCYTE; CELL LINEAGE; CELL SUBPOPULATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENHANCER REGION; GENE ACTIVITY; GENE EXPRESSION; HELPER CELL; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; REPORTER GENE; T LYMPHOCYTE ACTIVATION; THYMOCYTE; TRANSCRIPTION REGULATION; TRANSGENE;

EID: 33645780625     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.8.4880     Document Type: Article

References (40)

1. Davis, C. B., and D. R. Littman. 1994. Thymocyte lineage commitment: is it instructed or stochastic? Curr. Opin. Immunol. 6: 266-272.
2. Killeen, N., C. B. Davis, K. Chu, M. E. Crooks, S. Sawada, J. D. Scarborough, K. A. Boyd, S. G. Stuart, H. Xu, and D. R. Littman. 1993. CD4 function in thymocyte differentiation and T cell activation. Philos. Trans. R Soc. London B Biol. Sci. 342: 25-34.
3. Ellmeier, W., S. Sawada, and D. R. Littman. 1999. The regulation of CD4 and CDS coreceptor gene expression during T cell development. Annu. Rev. Immunol. 17: 523-554.
4. Adlam, M., and G. Siu. 2003. Hierarchical interactions control CD4 gene expression during thymocyte development. Immunity 18: 173-184.
5. Sawada, S., and D. R. Littman. 1991. Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene. Mol. Cell. Biol. 11: 5506-5515.
6. Sawada, S., and D. R. Littman. 1993. A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines. Mol Cell Biol. 13: 5620-5628.
7. Sawada, S., J. D. Scarborough, N. Killeen, and D. R. Littman. 1994. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 77: 917-929.
8. Siu, G., A. L. Wurster, D. D. Duncan, T. M. Soliman, and S. M. Hedrick. 1994. A transcriptional silencer controls the developmental expression of the CD4 gene. EMBO J. 13: 3570-3579.
9. Taniuchi, I., and D. R. Littman. 2004. Epigenetic gene silencing by Runx proteins. Oncogene 23: 4341-4345.
10. Taniuchi, I., M. Osato, T. Egawa, M. J. Sunshine, S. C. Bae, T. Komori, Y. Ito, and D. R. Littman. 2002. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during Tlymphocyte development. Cell 111: 621-633.
11. Chi, T. H., M. Wan, K. Zhao, I. Taniuchi, L. Chen, D. R. Littman, and G. R. Crabtree. 2002. Reciprocal regulation of CD4/CD8 expression by SWI/ SNF-like BAF complexes. Nature 418: 195-199.
12. Tamai, K., M. Semenov, Y. Kato, R. Spokony, C. Liu, Y. Katsuyama, F. Hess, J. P. Saint-Jeannet, and X. He. 2000. LDL-receptor-related proteins in Wnt signal transduction. Nature 407: 530-535.
13. Wehrli, M., S. T. Dougan, K. Caldwell, L. O'Keefe, S. Schwartz, D. Vaizel-Ohayon, E. Schejter, A. Tomlinson, and S. DiNardo. 2000. arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature 407: 527-530.
14. Pinson, K. I., J. Brennan, S. Monkley, B. J. Avery, and W. C. Skarnes. 2000. An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407: 535-538.
15. Cadigan, K. M., and R. Nusse. 1997. Wnt signaling: a common theme in animal development. Genes Dev. 11: 3286-3305.
16. Reya, T., A. W. Duncan, L. Ailles, J. Domen, D. C. Scherer, K. Willert, L. Hintz, R. Nusse, and I. L. Weissman. 2003. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423: 409-414.
17. Hurlstone, A., and H. Clevers. 2002. T-cell factors: turn-ons and turn-offs. EMBO J. 21: 2303-2311.
18. van de Wetering, M., W. de Lau, and H. Clevers. 2002. WNT signaling and lymphocyte development. Cell 109(Suppl): S13-S19.
19. Qiang, Y. W., and S. Rudikoff. 2004. Wnt signaling in B and T lymphocytes. Front Biosci. 9: 1000-1010.
20. Verbeek, S., D. Izon, F. Hofhuis, E. Robanus-Maandag, H. te Riele, M. van de Wetering, M. Oosterwegel, A. Wilson, H. R. MacDonald, and H. Clevers. 1995. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 374: 70-74.
21. + thymocyte survival. Nat. Immunol. 2: 691-697.
22. Schilham, M. W., A. Wilson, P. Moerer, B. J. Benaissa-Trouw, A. Cumano, and H. C. Clevers. 1998. Critical involvement of Tcf-1 in expansion of thymocytes. J. Immunol. 161: 3984-3991.
23. Gounari, F., I. Aifantis, K. Khazaie, S. Hoeflinger, N. Harada, M. M. Taketo, and H. von Boehmer. 2001. Somatic activation of β-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. Nat. Immunol. 2: 863-869.
24. Xu, Y., D. Banerjee, J. Huelsken, W. Birchmeier, and J. M. Sen. 2003. Deletion of β-catenin impairs T cell development. Nat. Immunol. 4: 1177-1182.
25. Gounari, F., R. Chang, J. Cowan, Z. Guo, M. Dose, E. Gounaris, and K. Khazaie. 2005. Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat. Immunol. 6: 800-809.
26. Aberle, H., A. Bauer, J. Stappert, A. Kispert, and R. Kemler. 1997. β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16: 3797-3804.
27. Roose, J., M. Molenaar, J. Peterson, J. Hurenkamp, H. Brantjes, P. Moerer, M. van de Wetering, O. Destree, and H. Clevers. 1998. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature 395: 608-612.
28. L. J. Immunol. 175: 7981-7988.
29. Williams, C. J., T. Naito, P. G. Arco, J. R. Seavitt, S. M. Cashman, B. De Souza, X. Qi, P. Keables, U. H. Von Andrian, and K. Georgopoulos. 2004. The chromatin remodeler Mi-2β is required for CD4 expression and T cell development. Immunity 20: 719-733.
30. Polakis, P. 2002. Casein kinase 1: a Wnt'er of disconnect. Curr. Biol. 12: R499-R501.
31. Germain, R. N. 2002. T-cell development and the CD4-CD8 lineage decision. Nat. Rev. Immunol. 2: 309-322.
32. Weinmann, A. S., and P. J. Farnham. 2002. Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods 26: 37-47.
33. τ. J. Biol Chem. 270: 20962-20967.
34. Cobas, M., A. Wilson, B. Ernst, S. J. Mancini, H. R. MacDonald, R. Kemler, and F. Radtke. 2004. β-Catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 199: 221-229.
35. Gillespie, F. P., L. Doros, J. Vitale, C. Blackwell, J. Gosselin, B. W. Snyder, and S. C. Wadsworth. 1993. Tissue-specific expression of human CD4 in transgenic mice. Mol. Cell Biol 13: 2952-2958.
36. Killeen, N., S. Sawada, and D. R. Littman. 1993. Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4. EMBO J. 12: 1547-1553.
37. + T cells and in macrophages of transgenic mice. Mol. Cell. Biol. 14: 1084-1094.
38. Zhuang, Y., P. Cheng, and H. Weintraub. 1996. B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol. Cell. Biol. 16: 2898-2905.
39. + thymocytes regulate proliferation and cell adhesion. J. Immunol. 172: 1099-1108.
40. Mulroy, T., Y. Xu, and J. M. Sen. 2003. β-Catenin expression enhances generation of mature thymocytes. Int. Immunol 15: 1485-1494.