Genetics of macrovascular complications in diabetes

Current Diabetes Reports

Volumn 6, Issue 2, 2006, Pages 162-168

  Fumeron, Frédéric ^b   Reis, André F ^b   Velho, Gilberto ^a  

^a INSERM   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; APOLIPOPROTEIN B; CHOLESTEROL ACYLTRANSFERASE; COLLAGEN TYPE 10; COLLAGEN TYPE 8; COMPLEMENT COMPONENT C1Q; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLUTATHIONE PEROXIDASE 1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN;

ALLELE; ATHEROSCLEROSIS; BLOOD CLOTTING; BLOOD VESSEL WALL; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DIABETIC ANGIOPATHY; DNA POLYMORPHISM; DYSLIPIDEMIA; ENERGY METABOLISM; ENVIRONMENTAL FACTOR; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GLUCOSE HOMEOSTASIS; HEART HEMODYNAMICS; HUMAN; HYPERTENSION; INFLAMMATION; LIPID METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; REVIEW; RISK ASSESSMENT; RISK FACTOR;

ADIPONECTIN; ALLELES; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; VARIATION (GENETICS);

EID: 33645767496     PISSN: 15344827     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11892-006-0028-5     Document Type: Review

References (49)

1. Kannel WB, McGee DL: Diabetes and cardiovascular disease. The Framingham study. JAMA 1979, 241:2035-2038.
2. Hansson GK: Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005, 352:1685-1695.
3. Lusis AJ, Mar R, Pajukanta P: Genetics of atherosclerosis. Annu Rev Genomics Hum Genet 2004, 5:189-218.
4. Stamler J, Vaccaro O, Neaton JD, Wentworth D: Diabetes, other risk factors, and 12-yr cardiovascular mortality fo men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993, 16:434-444.
5. Goldberg IJ: Why does diabetes increase atherosclerosis? I don't know! J Clin Invest 2004, 114:613-615.
6. Schildkraut JM, Myers RH, Cupples LA, et al.: Coronary risk associated with age and sex of parental heart disease in the Framingham Study. Am J Cardiol 1989, 64:555-559
7. Wang X, Ishimori N, Korstanje R, et al.: Identifying novel genes for atherosclerosis through mouse-human comparative genetics. Am J Hum Genet 2005, 77:1-15.
8. Wang D, Yang H, Quinones MJ, et al.: A genome-wide scan for carotid artery intima-media thickness: the Mexican-American Coronary Artery Disease family study. Stroke 2005, 36:540-545.
9. Cambien F: Coronary heart disease and polymorphisms in genes affecting lipid metabolism and inflammation. Curr Atheroscler Rep 2005, 7:188-195.
10. Ma X, Bacci S, Mlynarski W, et al.: A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet 2004, 13:2197-2205.
11. März W, Nauck M, Hoffmann MM, et al.: G(-30)A polymorphism in the pancreatic promoter of the glucokinase gene associated with angiographic coronary artery disease and type 2 diabetes mellitus. Circulation 2004, 109:2844-2849.
12. Hamanishi T, Furuta H, Kato H, et al.: Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients. Diabetes 2004, 53:2455-1460.
13. Yamada Y, Ichihara S, Izawa H, et al.: Genetic risk for coronary artery disease in individuals with or without type 2 diabetes. Mol Genet Metab 2004, 81:282-290.
14. Prudente S, Hribal ML, Flex E, et al.: The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 Is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy. Diabetes 2005, 54:2807-2811.
15. Bacci S, Ludovico O, Prudente S, et al.: The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction. Diabetes 2005, 54:3021-3025.
16. Bacci S, Menzaghi C, Ercolino T, et al.: The +276 G/T single nucleotide polymorphism of the adiponectin gene is associated with coronary artery disease in type 2 diabetic patients. Diabetes Care 2004, 27:2015-2020.
17. Lacquemant C, Froguel P, Lobbens S, et al.: The adiponectin gene SNP+45 is associated with coronary artery disease in type 2 (non-insulin-dependent) diabetes mellitus. Diabet Med 2004, 21:776-781.
18. Ohashi K, Ouchi N, Kihara S, et al.: Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease. J Am Coll Cardiol 2004, 43:1195-1200.
19. Qi L, Li T, Rimm E, et al.: The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men. Diabetes 2005, 54:1607-1610.
20. Hattersley AT, McCarthy MI: What makes a good genetic association study? Lancet 2005, 366:1315-1323.
21. Gable DR, Stephens JW, Humphries SE, Hurel SJ: The +276G>T adiponectin gene SNP is associated with cardiovascular disease in patients with type 2 diabetes mellitus. Diabetologia 2005, 48(suppl 1):A131.
22. Jaziri R, Bellili N, Maimaitiming S, et al.: T45G polymorphism of adiponectin gene and risk of myocardial infarction in type 2 diabetic subjects with high vascular risk: the DIABHYCAR study. Diabetes 2005, 54(suppl 1):A62.
23. Jiang JY, Jiang YD, Chiang FT, et al.: Positive association of a genetic variant of the APM1 with coronary artery disease. Diabetologia 2005, 48(suppl 1):A401.
24. Kang ES, Kim SH, Hur KY, et al.: Adiponectin gene polymorphism and carotid artery intima-media thickness in type 2 diabetes. Diabetes 2005, 54(suppl 1):A169.
25. Kretowski A, Gugala K, Bachurzewska-Gajewska H, et al.: Association of the promoter of adiponectin gene -11391G/A polymorphism with type 2 diabetes and coronary artery disease. Diabetes 2005, 54(suppl 1):A293.
26. Hara K, Boutin P, Mori Y, et al.: Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002, 51:536-540.
27. Stumvoll M, Tschritter O, Fritsche A, et al.: Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes 2002, 51:37-41.
28. Fumeron F, Aubert R, Siddiq A, et al.: Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study. Diabetes 2004, 53:1150-1157.
29. Pajvani UB, Hawkins M, Combs TP, et al.: Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 2004, 279:12152-12162.
30. Fruebis J, Tsao TS, Javorschi S. et al.: Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A 2001, 98:2005-2010.
31. Yamauchi T, Kamon J, Ito Y, et al.: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003, 423:762-769.
32. Yamauchi T, Kamon J, Minokoshi Y, et al.: Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002, 8:1288-1295.
33. Arita Y, Kihara S, Ouchi N, et al.: Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999, 257:79-83.
34. Hotta K, Funahashi T, Arita Y, et al.: Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000, 20:1595-1599.
35. Kumada M, Kihara S, Sumitsuji S, et al.: Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003, 23:85-89.
36. Zoccali C, Mallamaci F, Tripepi G, et al.: Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. J Am Soc Nephrol 2002, 13:134-141.
37. Pischon T, Girman CJ, Hotamisligil GS, et al.: Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 2004, 291:1730-1737.
38. Schulze MB, Shai I, Rimm EB, et al.: Adiponectin and future coronary heart disease events among men with type 2 diabetes. Diabetes 2005, 54:534-539.
39. Ng TW, Watts GF, Farvid MS, et al.: Adipocytokines and VLDL metabolism: independent regulatory effects of adiponectin, insulin resistance, and fat compartments on VLDL apolipoprotein B-100 kinetics? Diabetes 2005, 54:795-802.
40. Lawlor DA, Davey Smith C, Ebrahim S, et al.: Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women. J Clin Endocrinol Metab 2005, 90:5677-5683.
41. Ouchi N, Kihara S, Arita Y, et al.: Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999, 100:2473-2476.
42. Ouchi N, Kihara S, Arita Y, et al.: Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001, 103:1057-1063.
43. Furukawa K, Hori M, Ouchi N, et al.: Adiponectin downregulates acyl-coenzyme A:cholesterol acyltransferase-1 in cultured human monocyte-derived macrophages. Biochem Biophys Res Commun 2004, 317:831-836.
44. Shibata R, Sato K, Pimentel DR, et al.: Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med 2005, 11:1096-1103.
45. Velho G, Blanché H, Vaxillaire M, et al.: Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families. Diabetologia 1997, 40:217-224.
46. Goudriaan JR, Dahlmans VE, Teusink B, et al.: CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice. J Lipid Res 2003, 44:2270-2277.
47. Maddux BA, Goldfine ID: Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit. Diabetes 2000, 49:13-19.
48. Endler G, Mannhalter C, Sunder-Plassmann H, et al.: The K121Q polymorphism in the plasma cell membrane glycoprotein 1 gene predisposes to early myocardial infarction. J Mol Med 2002, 80:791-795.
49. Forgione MA, Cap A, Liao R, et al.: Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure. Circulation 2002, 106:1154-1158.