Chemonucleolytic effects of chondroitinase ABC on normal rabbit intervertebral discs: Course of action up to 10 days postinjection and minimum effective dose

Spine

Volumn 21, Issue 21, 1996, Pages 2405-2411

  Takahashi, Toyomi ^a   Kurihara, Hitoshi ^a   Nakajima, Shin Ichi ^a   Kato, Tadahiko ^a   Matsuzaka, Satoshi ^a   Sekiguchi, Tomoko ^a   Onaya, Mayumi ^a   Miyauchi, Satoshi ^a   Mizuno, Shyoji ^a   Horie, Katsuyuki ^a   Fujita, Yoshimasa ^a   Hirose, Tsuneo ^b  

^a SEIKAGAKU CORPORATION   (Japan)

^b OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

biochemistry; chemonucleolysis; chondroitinase ABC; histology; rabbit; radiograph

Indexed keywords

CHONDROITIN ABC LYASE; CHONDROITIN SULFATE; COLLAGEN; COLLAGEN FIBER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CHEMONUCLEOLYSIS; DOSE TIME EFFECT RELATION; FEMALE; INTERVERTEBRAL DISK; INTRATHECAL DRUG ADMINISTRATION; LUMBAR SPINE; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; RABBIT; SPINE RADIOGRAPHY; WATER CONTENT;

ANIMALS; CHONDROITIN LYASES; CHONDROITIN SULFATES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYALURONIC ACID; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK CHEMOLYSIS; KERATAN SULFATE; ORGAN SIZE; RABBITS; TIME FACTORS; WATER;

EID: 10544223744     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-199611010-00001     Document Type: Article

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