Backbone dynamics of human parathyroid hormone (1-34): Flexibility of the central region under different environmental conditions

Biopolymers - Peptide Science Section

Volumn 84, Issue 2, 2006, Pages 147-160

  Scian, Michele ^a   Marin, Massimiliano ^a   Bellanda, Massimo ^a   Tou, Liqiang ^b,c   Alexander, Joseph M ^b,d   Rosenblatt, Michael ^b,d   Chorev, Michael ^b   Peggion, Evaristo ^a   Mammi, Stefano ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Extracellular calcium homeostasis; Flexibility; Human parathyroid hormone (1 34); Membrane mimetic environment; Model free formalism; Reduced spectral density functions; Relaxation parameters

Indexed keywords

CALCIUM; CHEMICAL RELAXATION; HORMONES; MICELLES; PHOSPHATES; SOLUTIONS;

EXTRACELLULAR CALCIUM HOMEOSTASIS; FLEXIBILITY; HUMAN PARATHYROID HORMONE; MEMBRANE-MIMETIC ENVIRONMENTS; MODEL-FREE FORMALISM; REDUCED SPECTRAL DENSITY FUNCTIONS; RELAXATION PARAMETERS;

BIOMEDICAL ENGINEERING;

AMIDE; BUFFER; DODECYLPHOSPHORYLCHOLINE; GLYCINE; NITROGEN; PARATHYROID HORMONE[1-34]; PHOSPHATE; SODIUM CHLORIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENVIRONMENT; HORMONE DETERMINATION; HORMONE STRUCTURE; MICELLE; NUCLEAR OVERHAUSER EFFECT; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; SPECTROMETRY;

AMINO ACID SEQUENCE; BUFFERS; ESCHERICHIA COLI; GLUTATHIONE TRANSFERASE; HUMANS; HYDROPHOBICITY; MICELLES; MOLECULAR SEQUENCE DATA; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PHOSPHORYLCHOLINE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SODIUM CHLORIDE; SOLUTIONS;

EID: 33645742999     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20355     Document Type: Article

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