Conformational studies of mono- and bicyclic parathyroid hormone- related protein-derived agonists

Biochemistry

Volumn 36, Issue 34, 1997, Pages 10372-10383

  Mierke, Dale F ^a,b   Maretto, Stefano ^c   Schievano, Elisabetta ^c   DeLuca, Dominga ^c   Bisello, Alessandro ^d   Mammi, Stefano ^c   Rosenblatt, Michael ^d   Peggion, Evaristo ^c   Chorev, Michael ^d  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b CLARK UNIVERSITY   (United States)

^c UNIVERSITY OF PADOVA   (Italy)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ANABOLIC AGENT; CALCIUM; DRUG ANALOG; LACTAM; PARATHYROID HORMONE RELATED PROTEIN; TRIFLUOROETHANOL;

AGONIST; AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; DRUG CONFORMATION; GEOMETRY; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; RECEPTOR BINDING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIMULATION;

CIRCULAR DICHROISM; COMPUTER SIMULATION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEINS; RECEPTORS, PARATHYROID HORMONE; TRIFLUOROETHANOL;

EID: 0030881910     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970771o     Document Type: Article

References (37)

1. Chorev, M., and Rosenblatt, M. (1996) in Principles of Bone Biology (Bilezikian, J. P., Raisz, L. G., and Rodan, G. A., Eds.) pp 305-323, Academic Press, San Diego.
2. de Papp, A. E., and Stewart, A. F. (1993) Trends Endocrinol. Metab. 4, 181-187.
3. Goltzman, D., Hendy, G. N., and Banville, D. (1989) Trends Endocrinol. Metab., 39-44.
4. Maretto, S., Mammi, S., Bissacco, E., Peggion, E., Bisello, A., Rosenblatt, M., Chorev, M., and Mierke, D. (1997) Biochemistry 36, 3300-3307.
5. Bisello, A., Nakamoto, C., Rosenblatt, M., and Chorev, M. (1997) Biochemistry 36, 3293-3299.
6. Rodan, S. B., Wesolowski, G., Ianacone, J., Tiede, M. A., and Rodan, G. (1989) J. Endocrinol. 122, 219-227.
7. Greenfield, N., and Fasman, G. D. (1969) Biochemistry 8, 4108-4116.
8. Bodenhausen, G., Vold, R. L., and Vold, R. R. (1980) J. Magn. Reson. 37, 93-106.
9. Rance, M., Sørensen, O. W., Bodenhausen, G., Wagner, G., Ernst, R. R., and Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 117, 479-485.
10. Derome, A. E., and Williamson, M. P. (1990) J. Magn. Reson. 88, 177-185.
11. Bax, A., and Davis, D. G. (1985) J. Magn. Reson. 65, 355-360.
12. Griesinger, C., Otting, G., Wüthrich, K., and Ernst, R. R. (1988) J. Am. Chem. Soc. 110, 7870-7872.
13. Macura, S., Huang, Y., Suter, D., and Ernst, R. R. (1980) J. Magn. Reson. 43, 259-281.
14. Wüthrich, K., Billeter, M., and Braun, W. (1983) J. Mol. Biol. 169, 949-961.
15. Havel, T. F. (1991) Prog. Biophys. Mol. Biol. 56, 43-78.
16. Crippen, G. M., and Havel, T. F. (1988) Distance Geometry and Molecular Conformation, John Wiley, New York.
17. Kaptein, R., Boelens, R., Scheek, R. M., and van Gunsteren, W. F. (1988) Biochemistry 27, 5389-5395.
18. Mierke, D. F., Geyer, A., and Kessler, H. (1994) Int. J. Pept. Protein Res. 44, 325-331.
19. De Loof, H., Nilsson, L., Rigler, R. J. (1992) J. Am. Chem. Soc. 114, 4028-4036.
20. Neugebauer, W., Surewucz, W. K., Gordon, H. L., Somorjai, R. L., Sung, W., and Willick, G. (1992) Biochemistiy 31, 2056-2063.
21. Neugebauer, W., Barbier, J.-R., Sung, W. L., Whitfield, J. F., and Willick, G. E. (1995) Biochemistry 34, 8835-8842.
22. Klaus, W., Dieckmann, T., Wray, V., Schomburg, D., Wingender, E., and Mayer, H. (1991) Biochemistry 30, 6936-6942.
23. Marx, U. C., Austermann, S., Bayer, P., Aderman, K., Ejchart, A., Sticht, H., Walter, S., Schmid, F.-X., Jaenicke, R., Forssmann, W.-G., and Rösch, P. (1995) J. Biol. Chem. 270, 15194-15202.
24. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, John Wiley, New York.
25. Barlow, D. J., and Thornton, J. M. (1988) J. Mol. Biol. 201, 601-619.
26. Havel, T. F. (1990) Biopolymers 29, 1565-1585.
27. Wray, V., Federau, T., Gronwald, W., Mayer, H., Schomburg, D., Tegge, W., and Wingender, E. (1994) Biochemistry 33, 1684-1693.
28. Veber, D. F., and Freidinger, R. M. (1985) Trends Neurosci. 8, 392-396.
29. Chorev, M., Roubini, E., McKee, R. L., Gibbons, S. W., Goldman, M. E., Caulfield, M. P., and Rosenblatt, M. (1991) Biochemistry 30, 5968-5974.
30. Chorev, M., Epand, R. F., Rosenblatt, M., Caulfield, M. P., and Epand, R. M. (1993) Int. J. Pept. Protein Res. 42, 342-345.
31. Kapurniotu, A., and Taylor J. W. (1995) J. Med. Chem. 38, 836-847.
32. Houston M. E. Jr., Gannon C. L., Kay C. M., and Hodges, R. S. (1995) J. Pept. Sci. 1, 274-281.
33. Barden, J. A., and Kemp, B. E. (1989) Eur. J. Biochem. 184, 379-394.
34. Chorev, M., Goldman, M. E., McKee, R. L., Roubini, E., Levy, J. J., Gay, T., Reagan, J. E., Fisher, J. E., Caporale, L. H., Golub, E. E., Caulfield, M. P., Nutt, R. F., and Rosenblatt, M. (1990) Biochemistry 29, 1580-1586.
35. McFarlane, D. R., McFarlane, E. F., Barden, J. A., and Kemp, B. E. (1993) Biochim. Biophys. Acta 1162, 187-194.
36. Ray, F. R., Barden, J. A., and Kemp, B. E. (1993) Eur. J. Biochem. 211, 205-211.
37. Willis, K. J. (1994) Int. J. Pept. Protein Res. 43, 23-28.