-
1
-
-
0035292694
-
Lipoprotein lipase: Physiology, biochemistry, and molecular biology
-
Goldberg IJ, Merkel M. Lipoprotein lipase: physiology, biochemistry, and molecular biology. Front Biosci 2001; 6:388-405.
-
(2001)
Front Biosci
, vol.6
, pp. 388-405
-
-
Goldberg, I.J.1
Merkel, M.2
-
2
-
-
0036906508
-
Lipoprotein lipase: Genetics, lipid uptake, and regulation
-
Merkel M, Eckel RH, Goldberg IJ. Lipoprotein lipase: genetics, lipid uptake, and regulation. J Lipid Res 2002; 43:1997-2006.
-
(2002)
J Lipid Res
, vol.43
, pp. 1997-2006
-
-
Merkel, M.1
Eckel, R.H.2
Goldberg, I.J.3
-
3
-
-
0036775676
-
Lipoprotein lipase: The regulation of tissue specific expression and its role in lipid and energy metabolism
-
Preiss-Landl K, Zimmermann R, Hammerle G, Zechner R. Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism. Curr Opin Lipidol 2002; 13:471-481.
-
(2002)
Curr Opin Lipidol
, vol.13
, pp. 471-481
-
-
Preiss-Landl, K.1
Zimmermann, R.2
Hammerle, G.3
Zechner, R.4
-
4
-
-
0030853681
-
Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase
-
Jensen DR, Schlaepfer IR, Morin CL, et al. Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase. Am J Physiol Regul Integr Comp Physiol 1997; 273 (2 Pt 2):683-689.
-
(1997)
Am J Physiol Regul Integr Comp Physiol
, vol.273
, Issue.2 PART 2
, pp. 683-689
-
-
Jensen, D.R.1
Schlaepfer, I.R.2
Morin, C.L.3
-
5
-
-
0032746178
-
Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo
-
Babaev VR, Fazio S, Gleaves LA, et al. Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo. J Clin Invest 1999; 103:1697-1705.
-
(1999)
J Clin Invest
, vol.103
, pp. 1697-1705
-
-
Babaev, V.R.1
Fazio, S.2
Gleaves, L.A.3
-
6
-
-
0035032163
-
Overexpressing human lipoprotein lipase in mouse skeletal muscle is associated with insulin resistance
-
Ferreira LD, Pulawa LK, Jensen DR, Eckel RH. Overexpressing human lipoprotein lipase in mouse skeletal muscle is associated with insulin resistance. Diabetes 2001; 50:1064-1068.
-
(2001)
Diabetes
, vol.50
, pp. 1064-1068
-
-
Ferreira, L.D.1
Pulawa, L.K.2
Jensen, D.R.3
Eckel, R.H.4
-
7
-
-
0035912744
-
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
-
U S A
-
Kim JK, Fillmore JJ, Chen Y, et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A 2001; 98:7522-7527.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 7522-7527
-
-
Kim, J.K.1
Fillmore, J.J.2
Chen, Y.3
-
8
-
-
0036729604
-
Overexpression of muscle lipoprotein lipase and insulin sensitivity
-
Pulawa LK, Eckel RH. Overexpression of muscle lipoprotein lipase and insulin sensitivity. Curr Opin Clin Nutr Metab Care 2002; 5:569-574.
-
(2002)
Curr Opin Clin Nutr Metab Care
, vol.5
, pp. 569-574
-
-
Pulawa, L.K.1
Eckel, R.H.2
-
9
-
-
24744459686
-
Differential regulation and properties of angiopoietin-like proteins 3 and 4
-
Ge H, Cha JY, Gopal H, et al. Differential regulation and properties of angiopoietin-like proteins 3 and 4. J Lipid Res 2005; 46:1484-1490. This study made a side-by-side comparison of Angptl3 and -4 on their assembly and regulation by feeding status and nuclear receptors.
-
(2005)
J Lipid Res
, vol.46
, pp. 1484-1490
-
-
Ge, H.1
Cha, J.Y.2
Gopal, H.3
-
10
-
-
27844478786
-
Regulation of lipid metabolism via angiopoietin-like proteins
-
Kersten S. Regulation of lipid metabolism via angiopoietin-like proteins. Biochem Soc Trans 2005; 33 (Pt 5):1059-1062.
-
(2005)
Biochem Soc Trans
, vol.33
, Issue.5 PART
, pp. 1059-1062
-
-
Kersten, S.1
-
11
-
-
26244448038
-
Angiopoietin-like proteins: Potential new targets for metabolic syndrome therapy
-
Oike Y, Akao M, Kubota Y, Suda T. Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy. Trends Mol Med 2005; 11:473-479.
-
(2005)
Trends Mol Med
, vol.11
, pp. 473-479
-
-
Oike, Y.1
Akao, M.2
Kubota, Y.3
Suda, T.4
-
12
-
-
0036478902
-
Angptl3 regulates lipid metabolism in mice
-
Koishi R, Ando Y, Ono M, et al. Angptl3 regulates lipid metabolism in mice. Nat Genet 2002; 30:151-157.
-
(2002)
Nat Genet
, vol.30
, pp. 151-157
-
-
Koishi, R.1
Ando, Y.2
Ono, M.3
-
13
-
-
0037072759
-
ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase
-
Shimizugawa T, Ono M, Shimamura M, et al. ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase. J Biol Chem 2002; 277:33742-33748.
-
(2002)
J Biol Chem
, vol.277
, pp. 33742-33748
-
-
Shimizugawa, T.1
Ono, M.2
Shimamura, M.3
-
14
-
-
0037423738
-
Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes
-
Shimamura M, Matsuda M, Kobayashi S, et al. Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes. Biochem Biophys Res Commun 2003; 301:604-609.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 604-609
-
-
Shimamura, M.1
Matsuda, M.2
Kobayashi, S.3
-
15
-
-
1942516351
-
ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states
-
Inukai K, Nakashima Y, Watanabe M, et al. ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states. Biochem Biophys Res Commun 2004; 317:1075-1079.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 1075-1079
-
-
Inukai, K.1
Nakashima, Y.2
Watanabe, M.3
-
16
-
-
0034654426
-
Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis
-
Kim I, Kim HG, Kim H, et al. Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis. Biochem J 2000; 346 (Pt 3):603-610.
-
(2000)
Biochem J
, vol.346
, Issue.3 PART
, pp. 603-610
-
-
Kim, I.1
Kim, H.G.2
Kim, H.3
-
17
-
-
0034666157
-
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
-
Kersten S, Mandard S, Tan NS, et al. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem 2000; 275:28488-28493.
-
(2000)
J Biol Chem
, vol.275
, pp. 28488-28493
-
-
Kersten, S.1
Mandard, S.2
Tan, N.S.3
-
18
-
-
0343060983
-
Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation
-
Yoon JC, Chickering TW, Rosen ED, et al. Peroxisome proliferator- activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol Cell Biol 2000; 20:5343-5349.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5343-5349
-
-
Yoon, J.C.1
Chickering, T.W.2
Rosen, E.D.3
-
19
-
-
2342579597
-
Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes
-
Schmuth M, Haqq CM, Cairns WJ, et al. Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. J Invest Dermatol 2004; 122:971-983.
-
(2004)
J Invest Dermatol
, vol.122
, pp. 971-983
-
-
Schmuth, M.1
Haqq, C.M.2
Cairns, W.J.3
-
20
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
U S A
-
Backhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 2004; 101:15718-15723. This study presented evidence on the role of intestine-derived Angptl4 in energy acquisition from food, utilizing Angptl4 knockout mice.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 15718-15723
-
-
Backhed, F.1
Ding, H.2
Wang, T.3
-
21
-
-
1842478284
-
Food restriction regulates adipose-specific cytokines in pituitary gland but not in hypothalamus
-
Wiesner G, Morash BA, Ur E, Wilkinson M. Food restriction regulates adipose-specific cytokines in pituitary gland but not in hypothalamus. J Endocrinol 2004; 180:1-6.
-
(2004)
J Endocrinol
, vol.180
, pp. 1-6
-
-
Wiesner, G.1
Morash, B.A.2
Ur, E.3
Wilkinson, M.4
-
22
-
-
0036660804
-
Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: Role of hypoxia inducible factor 1alpha
-
Belanger AJ, Lu H, Date T, et al. Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: role of hypoxia inducible factor 1alpha. J Mol Cell Cardiol 2002; 34:765-774.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 765-774
-
-
Belanger, A.J.1
Lu, H.2
Date, T.3
-
23
-
-
0346457118
-
Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4
-
Ge H, Yang G, Huang L, et al. Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4. J Biol Chem 2004; 279:2038-2045. This provides evidence that Angptl4 is glycosylated and cleaved in vitro and in vivo.
-
(2004)
J Biol Chem
, vol.279
, pp. 2038-2045
-
-
Ge, H.1
Yang, G.2
Huang, L.3
-
24
-
-
0142149169
-
Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo
-
Ono M, Shimizugawa T, Shimamura M, et al. Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo. J Biol Chem 2003; 278:41804-4189. This presents evidence that Angptl3 is cleaved in human plasma.
-
(2003)
J Biol Chem
, vol.278
, pp. 41804-44189
-
-
Ono, M.1
Shimizugawa, T.2
Shimamura, M.3
-
25
-
-
20944447890
-
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
-
U S A
-
Xu A, Lam MC, Chan KW, et al. Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A 2005; 102:6086-6091. This study determined the induction of ANGPTL4 in humans by rosiglitazone and measured the plasma levels of ANGPTL4.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 6086-6091
-
-
Xu, A.1
Lam, M.C.2
Chan, K.W.3
-
26
-
-
13444302796
-
Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4
-
Ge H, Yang G, Yu X, et al. Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4. J Lipid Res 2004; 45:2071-2079. The authors determined the cysteine residues required for Angptl4 oligomerization and its importance for the potency of LPL inhibition by Angptl4.
-
(2004)
J Lipid Res
, vol.45
, pp. 2071-2079
-
-
Ge, H.1
Yang, G.2
Yu, X.3
-
27
-
-
0037984387
-
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity
-
Pajvani UB, Du X, Combs TP, et al. Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications for metabolic regulation and bioactivity. J Biol Chem 2003; 278:9073-9085.
-
(2003)
J Biol Chem
, vol.278
, pp. 9073-9085
-
-
Pajvani, U.B.1
Du, X.2
Combs, T.P.3
-
28
-
-
2442707674
-
Disulfide-dependent multimeric assembly of resistin family hormones
-
Patel SD, Rajala MW, Rossetti L, et al. Disulfide-dependent multimeric assembly of resistin family hormones. Science 2004; 304:1154-1158.
-
(2004)
Science
, vol.304
, pp. 1154-1158
-
-
Patel, S.D.1
Rajala, M.W.2
Rossetti, L.3
-
29
-
-
0037237779
-
Regulation of the angiopoietin-like protein 3 gene by LXR
-
Kaplan R, Zhang T, Hernandez M, et al. Regulation of the angiopoietin-like protein 3 gene by LXR. J Lipid Res 2003; 44:136-143.
-
(2003)
J Lipid Res
, vol.44
, pp. 136-143
-
-
Kaplan, R.1
Zhang, T.2
Hernandez, M.3
-
30
-
-
0038353226
-
Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor
-
Inaba T, Matsuda M, Shimamura M, et al. Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor. J Biol Chem 2003; 278:21344-21351.
-
(2003)
J Biol Chem
, vol.278
, pp. 21344-21351
-
-
Inaba, T.1
Matsuda, M.2
Shimamura, M.3
-
31
-
-
4444272417
-
Leptin and insulin down-regulate angiopoietin-like protein 3, a plasma triglyceride-increasing factor
-
Shimamura M, Matsuda M, Ando Y, et al. Leptin and insulin down-regulate angiopoietin-like protein 3, a plasma triglyceride-increasing factor. Biochem Biophys Res Commun 2004; 322:1080-1085.
-
(2004)
Biochem Biophys Res Commun
, vol.322
, pp. 1080-1085
-
-
Shimamura, M.1
Matsuda, M.2
Ando, Y.3
-
32
-
-
0037406906
-
Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma
-
Le Jan S, Amy C, Cazes A, et al. Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma. Am J Pathol 2003; 162:1521-1528.
-
(2003)
Am J Pathol
, vol.162
, pp. 1521-1528
-
-
Le Jan, S.1
Amy, C.2
Cazes, A.3
-
33
-
-
3342928716
-
Characterization of the 5′ regulatory region of the mouse angiopoietin-like protein 4
-
Yoshida K, Ono M, Koishi R, Furukawa H. Characterization of the 5′ regulatory region of the mouse angiopoietin-like protein 4. Vet Res Commun 2004; 28:299-305.
-
(2004)
Vet Res Commun
, vol.28
, pp. 299-305
-
-
Yoshida, K.1
Ono, M.2
Koishi, R.3
Furukawa, H.4
-
34
-
-
4544274752
-
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment
-
Mandard S, Zandbergen F, Tan NS, et al. The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment. J Biol Chem 2004; 279:34411-34420. This study demonstrated that ANGPTL4 is differentially processed in tissues and determined its plasma abundance in different human populations.
-
(2004)
J Biol Chem
, vol.279
, pp. 34411-34420
-
-
Mandard, S.1
Zandbergen, F.2
Tan, N.S.3
-
35
-
-
2442692690
-
Peroxisome proliferator-activated receptor β/δ regulates very low density lipoprotein production and catabolism in mice on a western diet
-
Akiyama TE, Lambert G, Nicol CJ, et al. Peroxisome proliferator-activated receptor β/δ regulates very low density lipoprotein production and catabolism in mice on a western diet. J Biol Chem 2004; 279:20874-20881.
-
(2004)
J Biol Chem
, vol.279
, pp. 20874-20881
-
-
Akiyama, T.E.1
Lambert, G.2
Nicol, C.J.3
-
36
-
-
26844540456
-
Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: Regulation of triglyceride metabolism
-
Koster A, Chao YB, Mosior M, et al. Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology 2005; 146:4943-4950. This comprehensive study described the phenotypes of transgenic mice overexpressing Angptl4 from liver and mice with global knockout of Angptl3, -4, or both. It demonstrated direct interaction of Angptl4 and LPL.
-
(2005)
Endocrinology
, vol.146
, pp. 4943-4950
-
-
Koster, A.1
Chao, Y.B.2
Mosior, M.3
-
37
-
-
24944468109
-
Microbial regulation of intestinal radiosensitivity
-
U S A
-
Crawford PA, Gordon JI. Microbial regulation of intestinal radiosensitivity. Proc Natl Acad Sci U S A 2005; 102:13254-13259.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 13254-13259
-
-
Crawford, P.A.1
Gordon, J.I.2
-
38
-
-
13444250891
-
Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart
-
U S A
-
Yu X, Burgess SC, Ge H, et al. Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart. Proc Natl Acad Sci U S A 2005; 102:1767-1772. This was the first study to describe the autocrine/paracrine role of Angptl4 in tissues in an LPL-dependent manner.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 1767-1772
-
-
Yu, X.1
Burgess, S.C.2
Ge, H.3
-
39
-
-
32644454369
-
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity
-
in press
-
Mandard S, Zandbergen F, van Straten E, et al. The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity. J Biol Chem 2006 (in press). This study demonstrated the role of Angptl4 over-expression in adipose tissue on accumulation of body fat.
-
(2006)
J Biol Chem
-
-
Mandard, S.1
Zandbergen, F.2
Van Straten, E.3
-
40
-
-
0037219502
-
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
-
Davis S, Papadopoulos N, Aldrich TH, et al. Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering. Nat Struct Biol 2003; 10:38-44.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 38-44
-
-
Davis, S.1
Papadopoulos, N.2
Aldrich, T.H.3
-
41
-
-
0037023683
-
Downregulation of adipose tissue lipoprotein lipase during fasting requires that a gene, separate from the lipase gene, is switched on
-
Bergo M, Wu G, Ruge T, Olivecrona T. Downregulation of adipose tissue lipoprotein lipase during fasting requires that a gene, separate from the lipase gene, is switched on. J Biol Chem 2002; 277:11927-11932.
-
(2002)
J Biol Chem
, vol.277
, pp. 11927-11932
-
-
Bergo, M.1
Wu, G.2
Ruge, T.3
Olivecrona, T.4
-
42
-
-
0038146909
-
The distribution of lipoprotein lipase in rat adipose tissue. Changes with nutritional state engage the extracellular enzyme
-
Wu G, Olivecrona G, Olivecrona T. The distribution of lipoprotein lipase in rat adipose tissue. Changes with nutritional state engage the extracellular enzyme. J Biol Chem 2003; 278:11925-11930.
-
(2003)
J Biol Chem
, vol.278
, pp. 11925-11930
-
-
Wu, G.1
Olivecrona, G.2
Olivecrona, T.3
|