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Volumn 151, Issue 2, 2000, Pages 133-143

Melatonin decreases cell proliferation and transformation in a melatonin receptor-dependent manner

Author keywords

Cancer; Desensitization; Human mt1 and MT2 melatonin receptors; Melatonin; Proliferation; Transformation

Indexed keywords

CYCLIC AMP; MELATONIN; MELATONIN RECEPTOR; RECEPTOR SUBTYPE;

EID: 0034646905     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00394-8     Document Type: Article
Times cited : (58)

References (42)
  • 1
    • 0028572548 scopus 로고
    • Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells
    • Molis T.M., Spriggs L.L., Hill S. Modulation of estrogen receptor mRNA expression by melatonin in MCF-7 human breast cancer cells. Mol. Endocrinol. 8:1994;1681-1690.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1681-1690
    • Molis, T.M.1    Spriggs, L.L.2    Hill, S.3
  • 2
    • 0028242248 scopus 로고
    • 5-Fluorouracil attenuates an oncostatic effect of melatonin on estrogen-sensitive human breast cancer cell (MCF7)
    • Furuya Y., Yamamoto K., Kohno N., Ku Y., Saitoh Y. 5-Fluorouracil attenuates an oncostatic effect of melatonin on estrogen-sensitive human breast cancer cell (MCF7). Cancer Lett. 81:1994;95-98.
    • (1994) Cancer Lett. , vol.81 , pp. 95-98
    • Furuya, Y.1    Yamamoto, K.2    Kohno, N.3    Ku, Y.4    Saitoh, Y.5
  • 3
    • 0027198134 scopus 로고
    • Human malignant melanoma cells express high affinity receptors for melatonin: Antiproliferative effects of melatonin and 6-chloromelatonin
    • Ying S.W., Niles L.P., Crocker C. Human malignant melanoma cells express high affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin. Eur. J. Pharmacol. 246:1993;89-96.
    • (1993) Eur. J. Pharmacol. , vol.246 , pp. 89-96
    • Ying, S.W.1    Niles, L.P.2    Crocker, C.3
  • 4
    • 0031021914 scopus 로고    scopus 로고
    • Melatonin in humans
    • Brzezinski A. Melatonin in humans. N Engl. J. Med. 336:1997;186-195.
    • (1997) N Engl. J. Med. , vol.336 , pp. 186-195
    • Brzezinski, A.1
  • 5
    • 0019780104 scopus 로고
    • Effect of melatonin on experimental tumors under different photoperiods and times of administration
    • Bartsch H., Bartsch C. Effect of melatonin on experimental tumors under different photoperiods and times of administration. J. Neural Transm. 52:1981;269-279.
    • (1981) J. Neural Transm. , vol.52 , pp. 269-279
    • Bartsch, H.1    Bartsch, C.2
  • 6
    • 0031229246 scopus 로고    scopus 로고
    • Nocturnal urinary 6-sulphatoxymelatonin excretion is decreased in primary breast cancer patients compared to age-matched controls and shows negative correlation with tumor-size
    • Bartsch C., Bartsch H., Karenovics A., Franz H., Peiker G., Mecke D. Nocturnal urinary 6-sulphatoxymelatonin excretion is decreased in primary breast cancer patients compared to age-matched controls and shows negative correlation with tumor-size. J. Pineal Res. 23:1997;53-58.
    • (1997) J. Pineal Res. , vol.23 , pp. 53-58
    • Bartsch, C.1    Bartsch, H.2    Karenovics, A.3    Franz, H.4    Peiker, G.5    Mecke, D.6
  • 7
    • 0031231111 scopus 로고    scopus 로고
    • Nocturnal urinary 6-sulfatoxymelatonin and proliferating cell nuclear antigen-immunopositive tumor cells show strong positive correlations in patients with gastrointestinal and lung cancer
    • Bartsch C., Kvetnoy I., Kvetnaia T., Bartsch H., Molotkov A., Franz H. Nocturnal urinary 6-sulfatoxymelatonin and proliferating cell nuclear antigen-immunopositive tumor cells show strong positive correlations in patients with gastrointestinal and lung cancer. J. Pineal Res. 23:1997;90-96.
    • (1997) J. Pineal Res. , vol.23 , pp. 90-96
    • Bartsch, C.1    Kvetnoy, I.2    Kvetnaia, T.3    Bartsch, H.4    Molotkov, A.5    Franz, H.6
  • 11
    • 0029909061 scopus 로고    scopus 로고
    • Melatonin in human breast cancer tissue: Association with nuclear grade and estrogen receptor status
    • Maestroni G.J.M., Conti A. Melatonin in human breast cancer tissue: association with nuclear grade and estrogen receptor status. Lab. Invest. 75:1996;557-561.
    • (1996) Lab. Invest. , vol.75 , pp. 557-561
    • Maestroni, G.J.M.1    Conti, A.2
  • 12
    • 0019811631 scopus 로고
    • Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene induced mammary tumors in the rat
    • Tamerkin L., Cohen M., Roselle D., Reichert C., Lippman M., Chabner B. Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene induced mammary tumors in the rat. Cancer Res. 41:1981;4432-4436.
    • (1981) Cancer Res. , vol.41 , pp. 4432-4436
    • Tamerkin, L.1    Cohen, M.2    Roselle, D.3    Reichert, C.4    Lippman, M.5    Chabner, B.6
  • 13
    • 0023025530 scopus 로고
    • Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotional phase of 7,12-dimethylbenz(alpha)-anthracene-induced (DMBA)-induced mammary tumorigenesis
    • Blask D.E., Hill S.M., Orstead K.M., Massa J.S. Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotional phase of 7,12-dimethylbenz(alpha)-anthracene-induced (DMBA)-induced mammary tumorigenesis. J. Neural Transm. 67:1986;125-138.
    • (1986) J. Neural Transm. , vol.67 , pp. 125-138
    • Blask, D.E.1    Hill, S.M.2    Orstead, K.M.3    Massa, J.S.4
  • 14
    • 0023929372 scopus 로고
    • Inhibition of dunning tumor growth by melatonin
    • Philo R., Berkowitz A.S. Inhibition of dunning tumor growth by melatonin. J. Urol. 139:1988;1099-1102.
    • (1988) J. Urol. , vol.139 , pp. 1099-1102
    • Philo, R.1    Berkowitz, A.S.2
  • 15
    • 0030604007 scopus 로고    scopus 로고
    • Effects of melatonin on the proliferation and differentiation of human neuroblastoma cells in culture
    • Cos S., Verduga R., Fernandez-Viadero C., Megias M., Crespo D. Effects of melatonin on the proliferation and differentiation of human neuroblastoma cells in culture. Neurosci. Lett. 266:1996;113-116.
    • (1996) Neurosci. Lett. , vol.266 , pp. 113-116
    • Cos, S.1    Verduga, R.2    Fernandez-Viadero, C.3    Megias, M.4    Crespo, D.5
  • 16
    • 0032513085 scopus 로고    scopus 로고
    • Melatonin's growth-inhibitory effect on hepatoma AH 130 in the rat
    • Cini G., Coronnello M., Mini E., Neri B. Melatonin's growth-inhibitory effect on hepatoma AH 130 in the rat. Cancer Lett. 125:1998;51-59.
    • (1998) Cancer Lett. , vol.125 , pp. 51-59
    • Cini, G.1    Coronnello, M.2    Mini, E.3    Neri, B.4
  • 17
    • 0031827090 scopus 로고    scopus 로고
    • Inhibition of cell proliferation: A mechanism likely to mediate the prevention of neuronal cell death by melatonin
    • Mayo J.C., Sainz R.M., Uria H., Antolin I., Esteban M.M., Rodriguez C. Inhibition of cell proliferation: a mechanism likely to mediate the prevention of neuronal cell death by melatonin. J. Pineal Res. 25:1998;12-18.
    • (1998) J. Pineal Res. , vol.25 , pp. 12-18
    • Mayo, J.C.1    Sainz, R.M.2    Uria, H.3    Antolin, I.4    Esteban, M.M.5    Rodriguez, C.6
  • 18
    • 0022498928 scopus 로고
    • Effects of melatonin on cancer: Studies on MCF-7 human breast cancer cells in culture
    • Blask D.E., Hill S.M. Effects of melatonin on cancer: studies on MCF-7 human breast cancer cells in culture. J. Neural. Transm. 21:1986;433-449.
    • (1986) J. Neural. Transm. , vol.21 , pp. 433-449
    • Blask, D.E.1    Hill, S.M.2
  • 19
    • 0028981509 scopus 로고
    • Melatonin inhibition of MCF-7 human breast-cancer cell growth: Influence of cell proliferation rate
    • Cos S., Sanchez-Barcelo E.J. Melatonin inhibition of MCF-7 human breast-cancer cell growth: influence of cell proliferation rate. Cancer Lett. 93:1995;207-212.
    • (1995) Cancer Lett. , vol.93 , pp. 207-212
    • Cos, S.1    Sanchez-Barcelo, E.J.2
  • 21
    • 0030614798 scopus 로고    scopus 로고
    • 17β-estradiol, diethylstilbestrol, tamoxifen, toremifene, and ICI 164,384 induce morphological transformation and aneuploidy in cultured Syrian hamster embryo cells
    • Tsutsui T., Taguchi S., Tanaka Y., Barrett J.C. 17β-estradiol, diethylstilbestrol, tamoxifen, toremifene, and ICI 164,384 induce morphological transformation and aneuploidy in cultured Syrian hamster embryo cells. Int. J. Cancer. 70:1997;188-193.
    • (1997) Int. J. Cancer , vol.70 , pp. 188-193
    • Tsutsui, T.1    Taguchi, S.2    Tanaka, Y.3    Barrett, J.C.4
  • 22
    • 0032188888 scopus 로고    scopus 로고
    • Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells
    • Cos S., Fernandez R., Guezmes A., Sanchez-Barcelo E.J. Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells. Cancer Res. 58:1998;4383-4390.
    • (1998) Cancer Res. , vol.58 , pp. 4383-4390
    • Cos, S.1    Fernandez, R.2    Guezmes, A.3    Sanchez-Barcelo, E.J.4
  • 23
    • 0026377775 scopus 로고
    • The pineal control of aging he effects of melatonin and pineal grafting on the survival of older mice
    • Pierpaoli W., Dall'ara A., Pedrinins E., Regelson W. The pineal control of aging he effects of melatonin and pineal grafting on the survival of older mice. Ann. N. Y. Acad. Sci. USA. 621:1991;291-313.
    • (1991) Ann. N. Y. Acad. Sci. USA , vol.621 , pp. 291-313
    • Pierpaoli, W.1    Dall'Ara, A.2    Pedrinins, E.3    Regelson, W.4
  • 24
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • Reppert S.M., Weaver D.R., Ebisawa T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron. 13:1994;1177-1185.
    • (1994) Neuron , vol.13 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 25
    • 0028054749 scopus 로고
    • Melatonin receptors: Localization, molecular pharmacology and physiological significance
    • Morgan P.J., Barrett P., Howell H.E., Helliwell R. Melatonin receptors: localization, molecular pharmacology and physiological significance. Neurochem. Int. 24:1994;101-146.
    • (1994) Neurochem. Int. , vol.24 , pp. 101-146
    • Morgan, P.J.1    Barrett, P.2    Howell, H.E.3    Helliwell, R.4
  • 26
    • 0029895791 scopus 로고    scopus 로고
    • Characterization and regulation of the human ML1A melatonin receptor stably expressed in chinese hamster ovary cells
    • Witt-Enderby P.A., Dubocovich M.L. Characterization and regulation of the human ML1A melatonin receptor stably expressed in chinese hamster ovary cells. Mol. Pharmacol. 50:1996;166-174.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 166-174
    • Witt-Enderby, P.A.1    Dubocovich, M.L.2
  • 27
    • 0031730734 scopus 로고    scopus 로고
    • Physiological exposure to melatonin supersensitizes the cyclic adenosine 3′,5′-monophosphate-dependent signal transduction cascade in chinese hamster ovary cells expressing the human mt1 melatonin receptor
    • Witt-Enderby P.A., Masana M.I., Dubocovich M. Physiological exposure to melatonin supersensitizes the cyclic adenosine 3′,5′-monophosphate-dependent signal transduction cascade in chinese hamster ovary cells expressing the human mt1 melatonin receptor. Endocrinology. 139:1998;3064-3071.
    • (1998) Endocrinology , vol.139 , pp. 3064-3071
    • Witt-Enderby, P.A.1    Masana, M.I.2    Dubocovich, M.3
  • 28
    • 0029115639 scopus 로고
    • Molecular characterization of a second melatonin receptor expressed in human retina and brain: The Mel1b melatonin receptor
    • Reppert S.M., Godson C., Mahle C.D., Weaver D.R., Slaugenhaupt S.A., Gusella J.F. Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor. Proc. Natl. Acad. Sci. USA. 92:1995;8734-8738.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8734-8738
    • Reppert, S.M.1    Godson, C.2    Mahle, C.D.3    Weaver, D.R.4    Slaugenhaupt, S.A.5    Gusella, J.F.6
  • 29
    • 0032565919 scopus 로고    scopus 로고
    • Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors
    • Ram P.T., Kiefer T., Silverman M., Song Y., Brown G.M., Hill S.M. Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors. Mol. Cell. Endocrinol. 141:1998;53-64.
    • (1998) Mol. Cell. Endocrinol. , vol.141 , pp. 53-64
    • Ram, P.T.1    Kiefer, T.2    Silverman, M.3    Song, Y.4    Brown, G.M.5    Hill, S.M.6
  • 30
    • 0031968571 scopus 로고    scopus 로고
    • Melatonin: Receptor-mediated events that may affect breast and other steroid hormone-dependent cancers
    • Baldwin W.S., Barrett J.C. Melatonin: receptor-mediated events that may affect breast and other steroid hormone-dependent cancers. Mol. Carcinog. 21:1998;149-155.
    • (1998) Mol. Carcinog. , vol.21 , pp. 149-155
    • Baldwin, W.S.1    Barrett, J.C.2
  • 31
    • 0031896573 scopus 로고    scopus 로고
    • Intracellular melatonin distribution in cultured cell lines
    • Finocchiaro L.M.E., Glikin G.C. Intracellular melatonin distribution in cultured cell lines. J. Pineal Res. 24:1998;22-34.
    • (1998) J. Pineal Res. , vol.24 , pp. 22-34
    • Finocchiaro, L.M.E.1    Glikin, G.C.2
  • 32
    • 0027301992 scopus 로고
    • Calmodulin mediates melatonin cytoskeletal effects
    • Benitez-King G., Anton-Tay F. Calmodulin mediates melatonin cytoskeletal effects. Experientia. 49:1993;635-641.
    • (1993) Experientia , vol.49 , pp. 635-641
    • Benitez-King, G.1    Anton-Tay, F.2
  • 33
    • 0014604721 scopus 로고
    • Murine sarcoma and leukemia viruses: Assay using clonal lines of contact-inhibited mouse cells
    • Jainchill J., Aaronson S.A., Todaro G.J. Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibited mouse cells. J. Virol. 4:1969;549-553.
    • (1969) J. Virol. , vol.4 , pp. 549-553
    • Jainchill, J.1    Aaronson, S.A.2    Todaro, G.J.3
  • 34
  • 35
    • 0029984571 scopus 로고    scopus 로고
    • Differences in agonist-independent and -dependent 5-hydroxytryptamine 2c receptor-mediated cell division
    • Westphal R.S., Sanders-Bush E. Differences in agonist-independent and -dependent 5-hydroxytryptamine 2c receptor-mediated cell division. Mol. Pharmacol. 49:1996;474-480.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 474-480
    • Westphal, R.S.1    Sanders-Bush, E.2
  • 36
    • 85047676942 scopus 로고    scopus 로고
    • The mel1a melatonin receptor is coupled to parallel signal transduction pathways
    • Godson C., Reppert S.M. The mel1a melatonin receptor is coupled to parallel signal transduction pathways. Endocrinology. 138:1997;397-404.
    • (1997) Endocrinology , vol.138 , pp. 397-404
    • Godson, C.1    Reppert, S.M.2
  • 37
    • 0028907243 scopus 로고
    • Melatonin receptors: Are there multiple subtypes
    • Dubocovich M.L. Melatonin receptors: are there multiple subtypes. Trends Pharmacol. Sci. 16:1995;50-56.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 50-56
    • Dubocovich, M.L.1
  • 38
    • 0030032765 scopus 로고    scopus 로고
    • Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatonin
    • Cos S., Recio J., Sanchez-Barcelo E.J. Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatonin. Life Sci. 58:1996;811-816.
    • (1996) Life Sci. , vol.58 , pp. 811-816
    • Cos, S.1    Recio, J.2    Sanchez-Barcelo, E.J.3
  • 39
    • 0026347077 scopus 로고
    • Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis
    • Najid A., Ratinaud M.-H. Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis. Tumori. 77:1991;385-390.
    • (1991) Tumori , vol.77 , pp. 385-390
    • Najid, A.1    Ratinaud, M.-H.2
  • 41
    • 0031956895 scopus 로고    scopus 로고
    • Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor
    • Guh J.H., Hwang T.L., Ko F., Chueh S., Lai M., Teng C. Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donor. Mol. Pharmacol. 53:1998;467-474.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 467-474
    • Guh, J.H.1    Hwang, T.L.2    Ko, F.3    Chueh, S.4    Lai, M.5    Teng, C.6
  • 42
    • 0030066986 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinase in the pars tuberalis of the ovine pituitary: Interactions between melatonin, insulin-like growth factor-1, and forskolin
    • Hazlerigg D.G., Thompson M., Hastings M.H., Morgan P.J. Regulation of mitogen-activated protein kinase in the pars tuberalis of the ovine pituitary: interactions between melatonin, insulin-like growth factor-1, and forskolin. Endocrinology. 137:1996;210-218.
    • (1996) Endocrinology , vol.137 , pp. 210-218
    • Hazlerigg, D.G.1    Thompson, M.2    Hastings, M.H.3    Morgan, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.