Histamine H1 receptor-stimulated interleukin 8 and granulocyte macrophage colony-stimulating factor production by bronchial epithelial cells requires extracellular signal-regulated kinase signaling via protein kinase C

International Archives of Allergy and Immunology

Volumn 139, Issue 4, 2006, Pages 279-293

  Matsubara, Masahiro ^a   Ohmori, Kenji ^a   Hasegawa, Kazuhide ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

Epidermal growth factor receptor; Extracellular signal regulated kinase; Histamine H1 receptor; Protein kinase C

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CALCIUM ION; CYCLIC AMP; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; INTERLEUKIN 8; MARCKS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLOPATADINE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; HISTAMINE; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; BRONCHUS MUCOSA; CALCIUM CELL LEVEL; CELL LINE; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EVALUATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY TRACT INFLAMMATION; SECOND MESSENGER; SIGNAL TRANSDUCTION; BIOSYNTHESIS; BRONCHUS; CYTOLOGY; METABOLISM; MUCUS; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA; SECRETION;

BRONCHI; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTAMINE; HUMANS; INTERLEUKIN-8; MUCUS; PROTEIN KINASE C; RECEPTORS, HISTAMINE H1; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION;

EID: 33645470600     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000091599     Document Type: Article

References (36)

1. Hill SJ, Ganellin CR, Timmerman H, Schwartz JC, Shankley NP, Young JM, Schunack W, Levi R, Haas HL: International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol Rev 1997;49:253-278.
2. Metcalfe DD, Baram D, Mekori YA: Mast cells. Physiol Rev 1997;77:1033-1079.
3. 1-antihistamines in asthma. Clin Allergy Immunol 2002;17:221-248.
4. Oda T, Morikawa N, Saito Y, Masuho Y, Matsumoto S: Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J Biol Chem 2000;275:36781-36786.
5. 2+-dependent protein kinase C, Raf/MEK/ERK and IKK/IkappaB/NF-kappaB signal cascades. Biochem Pharmacol 2005;69:433-449.
6. Kanda N, Watanabe S: Histamine enhances the production of granulocyte-macrophage colony-stimulating factor via protein kinase C alpha and extracellular signal-regulated kinase in human keratinocytes. J Invest Dermatol 2004; 122:863-872.
7. Takizawa H, Ohtoshi T, Kikutani T, Okazaki H, Akiyama N, Sato M, Shoji S, Ito K: Histamine activates bronchial epithelial cells to release inflammatory cytokines in vitro. Int Arch Allergy Immunol 1995;108:260-267.
8. Arima M, Plitt J, Stellato C, Bickel C, Motojima S, Makino S, Fukuda T, Schleimer PP: Expression of interleukin-16 by human epithelial cells. Inhibition by dexamethasone. Am J Respir Cell Mol Biol 1999;21:684-692.
9. Jeannin P, Delneste Y, Gosset P, Molet S, Lassalle P, Hamid Q, Tsicopoulos A, Tonnel AB: Histamine induces interleukin-8 secretion by endothelial cells. Blood 1994;84:2229-2233.
10. Caron G, Delneste Y, Roelandts E, Duez C, Herbault N, Magistrelli G, Bonnefoy JY, Pestel J, Jeannin P: Histamine induces CD86 expression and chemokine production by human immature dendritic cells. J Immunol 2001;166:6000-6006.
11. Miki I, Kusano A, Ohta S, Hanai N, Otoshi M, Masaki S, Sato S, Ohmori K: Histamine enhanced the TNF-alpha-induced expression of E-selectin and ICAM-1 on vascular endothelial cells. Cell Immunol 1996;171:285-288.
12. Yanni JM, Weimer LK, Sharif NA, Xu SX, Gamache DA, Spellman JM: Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs. Arch Ophthalmol 1999;117:643-647.
13. Pawankar R: Epithelial cells as immunoregulators in allergic airway diseases. Curr Opin Allergy Clin Immunol 2002;2:1-5.
14. Johnson GL, Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002;298:1911-1912.
15. Kawaguchi M, Onuchic LF, Huang SK: Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1. J Biol Chem 2002;277:15229-15232.
16. Hashimoto S, Gon Y, Takeshita I, Matsumoto K, Jibiki I, Takizawa H, Kudoh S, Horie T: Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation. Am J Respir Crit Care Med 2000;161:280-285.
17. Jibiki I, Hashimoto S, Maruoka S, Gon Y, Matsuzawa A, Nishitoh H, Ichijo H, Horie T: Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates nitric oxide-induced activator protein-1 activation in human bronchial epithelial cells. Am J Respir Crit Care Med 2003;167:856-861.
18. Takeyama K, Dabbagh K, Lee HM, Agusti C, Lausier JA, Ueki IF, Grattan KM, Nadel JA: Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci USA 1999;96:3081-3086.
19. Perrais M, Pigny P, Copin MC, Aubert JP, Van Seuningen I: Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1. J Biol Chem 2002;277:32258-32267.
20. Adachi T, Cui CH, Kanda A, Kayaba H, Ohta K, Chihara J: Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells. Biochem Biophys Res Commun 2004;320:292-296.
21. Wu J, Cunnick JM: Trans-regulation of epidermal growth factor receptor by lysophosphatidic acid and G protein-coupled receptors. Biochim Biophys Acta 2002;1582:100-106.
22. Ohmori K, Hasegawa K, Tamura T, Miyake K, Matsubara M, Masaki S, Karasawa A, Urayama N, Horikoshi K, Kajita J, Hasegawa M, Taniguchi K, Komada T, Kawamoto Y: Properties of olopatadine hydrochloride, a new antiallergic/ antihistaminic drug. Arzneimittelforschung 2004;54:809-829.
23. 1 receptor. Eur J Pharmacol 1998;345:111-117.
24. Drouin SM, Cony DB, Hollman TJ, Kildsgaard J, Wetsel RA: Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy. J Immunol 2002;169:5926-5933.
25. Hewson CA, Edbrooke MR, Johnston SL: PMA induces the MUC5AC respiratory mucin in human bronchial epithelial cells, via PKC, EGF/TGF-alpha, Ras/Raf, MEK, ERK and Sp1-dependent mechanisms. J Mol Biol 2004;344:683-695.
26. Kemp PA, Sugar RA, Jackson AD: Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells. Am J Respir Cell Mol Biol 2004;31:446-455.
27. Cammarota M, Bevilaqua LR. Rostas JA, Dunkley PR: Histamine activates tyrosine hydroxylase in bovine adrenal chromaffin cells through a pathway that involves ERK1/2 but not p38 or JNK. J Neurochem 2003;84:453-458.
28. Li Y, Martin LD, Spizz G, Adler KB: MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro. J Biol Chem 2001;276:40982-40990.
29. Lordan JL, Bucchieri F, Richter A, Konstantinidis A, Holloway JW, Thomber M, Puddicombe SM, Buchanan D, Wilson SJ, Djukanovic R, Holgate ST, Davies DE: Cooperative effects of Th2 cytokines and allergen on normal and asthmatic bronchial epithelial cells. J Immunol 2002;169:407-414.
30. Wang JH, Trigg CJ, Devalia JL, Jordan S, Davies RJ: Effect of inhaled beclomethasone dipropionate on expression of proinflammatory cytokines and activated eosinophils in the bronchial epithelium of patients with mild asthma. J Allergy Clin Immunol 1994;94:1025-1034.
31. Soderberg M, Lundgren R, Bjermer L, Stjernberg N, Rosenhall L: Inflammatory response in bronchoalveolar lavage fluid after inhaling histamine. Allergy 1989;44:98-102.
32. Jahnz-Rozyk K, Pirozynska E, Pojda Z: The effect of bronchial inhalation provocation tests on levels of interleukin-8 in material from broncho-alveolar fluid of patients with atopic bronchial asthma. Pol Merkuriusz Lek 1997;2:32-35.
33. Soderberg M, Lundgren R, Bjermer L, Angstrom T: Inhaled methacholine does not influence the cellular composition of bronchoalveolar lavage fluid. Allergy 1993;48:173-176.
34. Ohmori K, Ishii H, Sasaki Y, Ikemura T, Manabe H, Kitamura S: Effects of KW-4679, a new orally active antiallergic drug, on antigen-induced bronchial hyperresponsiveness, airway inflammation and immediate and late asthmatic responses in guinea pigs. Int Arch Allergy Immunol 1996;110:64-72.
35. Chang F, Steelman LS, Lee JT, Shelton JG, Navolanic PM, Blalock WL, Franklin RA, McCubrey JA: Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. Leukemia 2003;17:1263-1293.
36. Holgate ST, Peters-Golden M, Panettieri RA Jr, Henderson WA: Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. J Allergy Clin Immunol 2003;111(suppl 1):S18-S34.