A potential novel strategy to separate therapeutic- and side-effects that are mediated via the same receptor: β-arrestin2/G-protein coupling antagonists

Journal of Clinical Pharmacy and Therapeutics

Volumn 31, Issue 2, 2006, Pages 119-128

  Bruns, I R ^a   Chhum, S ^a   Dinh, A T ^a   Doerr, H ^a   Dunn, N R ^a   Ly, Y T ^a   Mitman, C L ^a   Rickards, H D ^a   Sol, C ^a   Wan, E W ^a   Raffa, R B ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN; DIAMORPHINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ETORPHINE; FENTANYL; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL; LOPERAMIDE; METHADONE; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST; OPIATE; RECEPTOR SUBTYPE;

ANALGESIA; ANTINOCICEPTION; COGNITIVE DEFECT; CONSTIPATION; DRUG DESIGN; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; HYPERACTIVITY; INTESTINE TRANSIT TIME; KNOCKOUT MOUSE; LOCOMOTION; NONHUMAN; OPIATE ADDICTION; RESPIRATION DEPRESSION; REVIEW; SIGNAL TRANSDUCTION;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; ARRESTINS; HUMANS; MORPHINE; RECEPTORS, G-PROTEIN-COUPLED;

EID: 33645466577     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1007/s00761-005-1011-5     Document Type: Review

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