-
1
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene
-
Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 1993; 12:4251-9.
-
(1993)
EMBO J
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
2
-
-
0028793371
-
Autonomous endodermal determination in Xenopus: Regulation of expression of the pancreatic gene XlHbox 8
-
Gamer LW, Wright CV. Autonomous endodermal determination in Xenopus: Regulation of expression of the pancreatic gene XlHbox 8. Dev Biol 1995; 171:240-51.
-
(1995)
Dev Biol
, vol.171
, pp. 240-251
-
-
Gamer, L.W.1
Wright, C.V.2
-
3
-
-
0036005768
-
Defining the cell lineages of the islets of Langerhans using transgenic mice
-
Herrera PL. Defining the cell lineages of the islets of Langerhans using transgenic mice. Int J Dev Biol 2002; 46:97-103.
-
(2002)
Int J Dev Biol
, vol.46
, pp. 97-103
-
-
Herrera, P.L.1
-
4
-
-
0034121735
-
Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
-
Herrera PL. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000; 127:2317-22.
-
(2000)
Development
, vol.127
, pp. 2317-2322
-
-
Herrera, P.L.1
-
5
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002; 129:2447-57.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
6
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
USA
-
Gradwohl G, Dierich A, LeMeur M, Guillemot F. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci USA 2000; 97:1607-11.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
7
-
-
25844456544
-
Genetic determinants of pancreatic epsilon-cell development
-
Heller RS, Jenny M, Collombat P, Mansouri A, Tomasetto C, Madsen OD, Mellitzer G, Gradwohl G, Serup P. Genetic determinants of pancreatic epsilon-cell development. Dev Biol 2005; 286:217-24.
-
(2005)
Dev Biol
, vol.286
, pp. 217-224
-
-
Heller, R.S.1
Jenny, M.2
Collombat, P.3
Mansouri, A.4
Tomasetto, C.5
Madsen, O.D.6
Mellitzer, G.7
Gradwohl, G.8
Serup, P.9
-
8
-
-
1542267814
-
Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development
-
USA
-
Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Natl Acad Sci USA 2004; 101:2924-9.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 2924-2929
-
-
Prado, C.L.1
Pugh-Bernard, A.E.2
Elghazi, L.3
Sosa-Pineda, B.4
Sussel, L.5
-
9
-
-
0035863135
-
Intercellular signals regulating pancreas development and function
-
Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function. Genes Dev 2001; 15:111-27.
-
(2001)
Genes Dev
, vol.15
, pp. 111-127
-
-
Kim, S.K.1
Hebrok, M.2
-
10
-
-
0036301577
-
Pancreatic organogenesis - Developmental mechanisms and implications for therapy
-
Edlund H. Pancreatic organogenesis - developmental mechanisms and implications for therapy. Nat Rev Genet 2002; 3:524-32.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 524-532
-
-
Edlund, H.1
-
11
-
-
0037706944
-
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate
-
Kumar M, Jordan N, Melton D, Grapin-Botton A. Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate. Dev Biol 2003; 259:109-22.
-
(2003)
Dev Biol
, vol.259
, pp. 109-122
-
-
Kumar, M.1
Jordan, N.2
Melton, D.3
Grapin-Botton, A.4
-
12
-
-
0035694459
-
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
-
Bhushan A, Itoh N, Kato S, Thiery JP, Czernichow P, Bellusci S, Scharfmann R. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 2001; 128:5109-17.
-
(2001)
Development
, vol.128
, pp. 5109-5117
-
-
Bhushan, A.1
Itoh, N.2
Kato, S.3
Thiery, J.P.4
Czernichow, P.5
Bellusci, S.6
Scharfmann, R.7
-
13
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H. Notch signalling controls pancreatic cell differentiation. Nature 1999; 400:877-81.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe De Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
14
-
-
14644423815
-
Development and cancer: Lessons learned in the pancreas
-
Heiser PW, Hebrok M. Development and cancer: Lessons learned in the pancreas. Cell Cycle 2004; 3:270-2.
-
(2004)
Cell Cycle
, vol.3
, pp. 270-272
-
-
Heiser, P.W.1
Hebrok, M.2
-
15
-
-
0036105502
-
Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations
-
Abraham SC, Klimstra DS, Wilentz RE, Yeo CJ, Conlon K, Brennan M, Cameron JL, Wu TT, Hruban RH. Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations. Am J Pathol 2002; 160:1361-9.
-
(2002)
Am J Pathol
, vol.160
, pp. 1361-1369
-
-
Abraham, S.C.1
Klimstra, D.S.2
Wilentz, R.E.3
Yeo, C.J.4
Conlon, K.5
Brennan, M.6
Cameron, J.L.7
Wu, T.T.8
Hruban, R.H.9
-
16
-
-
0036120621
-
Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: Frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway
-
Abraham SC, Wu TT, Hruban RH, Lee JH, Yeo CJ, Conlon K, Brennan M, Cameron JL, Klimstra DS. Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: Frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway. Am J Pathol 2002; 160:953-62.
-
(2002)
Am J Pathol
, vol.160
, pp. 953-962
-
-
Abraham, S.C.1
Wu, T.T.2
Hruban, R.H.3
Lee, J.H.4
Yeo, C.J.5
Conlon, K.6
Brennan, M.7
Cameron, J.L.8
Klimstra, D.S.9
-
17
-
-
0035152551
-
Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas: Frequent alterations in the APC/beta-catenin pathway and chromosome 11p
-
Abraham SC, Wu TT, Klimstra DS, Finn LS, Lee JH, Yeo CJ, Cameron JL, Hruban RH. Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas: Frequent alterations in the APC/beta-catenin pathway and chromosome 11p. Am J Pathol 2001; 159:1619-27.
-
(2001)
Am J Pathol
, vol.159
, pp. 1619-1627
-
-
Abraham, S.C.1
Wu, T.T.2
Klimstra, D.S.3
Finn, L.S.4
Lee, J.H.5
Yeo, C.J.6
Cameron, J.L.7
Hruban, R.H.8
-
18
-
-
0035577867
-
Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm
-
Tanaka Y, Kato K, Notohara K, Hojo H, Ijiri R, Miyake T, Nagahara N, Sasaki F, Kitagawa N, Nakatani Y, Kobayashi Y. Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm. Cancer Res 2001; 61:8401-4.
-
(2001)
Cancer Res
, vol.61
, pp. 8401-8404
-
-
Tanaka, Y.1
Kato, K.2
Notohara, K.3
Hojo, H.4
Ijiri, R.5
Miyake, T.6
Nagahara, N.7
Sasaki, F.8
Kitagawa, N.9
Nakatani, Y.10
Kobayashi, Y.11
-
19
-
-
24944487996
-
Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development
-
Dessimoz J, Bonnard C, Huelsken J, Grapin-Botton A. Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development. Curr Biol 2005; 15:1677-83.
-
(2005)
Curr Biol
, vol.15
, pp. 1677-1683
-
-
Dessimoz, J.1
Bonnard, C.2
Huelsken, J.3
Grapin-Botton, A.4
-
20
-
-
0036842027
-
Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation
-
Heller RS, Dichmann DS, Jensen J, Miller C, Wong G, Madsen OD, Serup P. Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn 2002; 225:260-70.
-
(2002)
Dev Dyn
, vol.225
, pp. 260-270
-
-
Heller, R.S.1
Dichmann, D.S.2
Jensen, J.3
Miller, C.4
Wong, G.5
Madsen, O.D.6
Serup, P.7
-
21
-
-
28044449357
-
{beta}-catenin is essential for pancreatic acinar but not islet development
-
Murtaugh LC, Law AC, Dor Y, Melton DA. {beta}-catenin is essential for pancreatic acinar but not islet development. Development 2005.
-
(2005)
Development
-
-
Murtaugh, L.C.1
Law, A.C.2
Dor, Y.3
Melton, D.A.4
-
22
-
-
25844530871
-
Attenuated wnt signaling perturbs pancreatic growth but not pancreatic function
-
Papadopoulou S, Edlund H. Attenuated wnt signaling perturbs pancreatic growth but not pancreatic function. Diabetes 2005; 54:2844-51.
-
(2005)
Diabetes
, vol.54
, pp. 2844-2851
-
-
Papadopoulou, S.1
Edlund, H.2
-
23
-
-
0036860704
-
The Wnt signalling pathway
-
Huelsken J, Behrens J. The Wnt signalling pathway. J Cell Sci 2002; 115:3977-8.
-
(2002)
J Cell Sci
, vol.115
, pp. 3977-3978
-
-
Huelsken, J.1
Behrens, J.2
-
24
-
-
0032406715
-
Mechanisms of Wnt signaling in development
-
Wodarz A, Nusse R. Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 1998; 14:59-88.
-
(1998)
Annu Rev Cell Dev Biol
, vol.14
, pp. 59-88
-
-
Wodarz, A.1
Nusse, R.2
-
25
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with beta-catenin, APC and GSK3beta
-
Behrens J, Jerchow BA, Wurtele M, Grimm J, Asbrand C, Wirtz R, Kuhl M, Wedlich D, Birchmeier W. Functional interaction of an axin homolog, conductin, with beta-catenin, APC and GSK3beta. Science 1998; 280:596-9.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
Grimm, J.4
Asbrand, C.5
Wirtz, R.6
Kuhl, M.7
Wedlich, D.8
Birchmeier, W.9
-
26
-
-
0036148208
-
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
-
Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 2002; 22:1172-83.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1172-1183
-
-
Jho, E.H.1
Zhang, T.2
Domon, C.3
Joo, C.K.4
Freund, J.N.5
Costantini, F.6
-
27
-
-
0036149985
-
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
-
Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, Karsten U, van de Wetering M, Clevers H, Schlag PM, Birchmeier W, Behrens J. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol 2002; 22:1184-93.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1184-1193
-
-
Lustig, B.1
Jerchow, B.2
Sachs, M.3
Weiler, S.4
Pietsch, T.5
Karsten, U.6
Van De Wetering, M.7
Clevers, H.8
Schlag, P.M.9
Birchmeier, W.10
Behrens, J.11
-
28
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004; 303:1483-7.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
29
-
-
0034614941
-
Regulation of cadherin adhesive activity
-
Gumbiner BM. Regulation of cadherin adhesive activity. J Cell Biol 2000; 148:399-404.
-
(2000)
J Cell Biol
, vol.148
, pp. 399-404
-
-
Gumbiner, B.M.1
-
30
-
-
0036228744
-
Intercellular adhesion, signalling and the cytoskeleton
-
Jamora C, Fuchs E. Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol 2002; 4:E101-8.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Jamora, C.1
Fuchs, E.2
-
31
-
-
27144552677
-
Nontraditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein
-
Hanson CA, Miller JR. Nontraditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein. Gene 2005; 361:1-12.
-
(2005)
Gene
, vol.361
, pp. 1-12
-
-
Hanson, C.A.1
Miller, J.R.2
-
32
-
-
0344740017
-
Expression of Wnt, Frizzled, sFRP and DKK genes in adult human pancreas
-
Heller RS, Klein T, Ling Z, Heimberg H, Katoh M, Madsen OD, Serup P. Expression of Wnt, Frizzled, sFRP and DKK genes in adult human pancreas. Gene Expr 2003; 11:141-7.
-
(2003)
Gene Expr
, vol.11
, pp. 141-147
-
-
Heller, R.S.1
Klein, T.2
Ling, Z.3
Heimberg, H.4
Katoh, M.5
Madsen, O.D.6
Serup, P.7
-
33
-
-
0032122460
-
Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family
-
Leimeister C, Bach A, Gessler M. Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech Dev 1998; 75:29-42.
-
(1998)
Mech Dev
, vol.75
, pp. 29-42
-
-
Leimeister, C.1
Bach, A.2
Gessler, M.3
-
34
-
-
0035034603
-
Inactivation of the beta-catenin gene by Wnt1-Cremediated deletion results in dramatic brain malformation and failure of craniofacial development
-
Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. Inactivation of the beta-catenin gene by Wnt1-Cremediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 2001; 128:1253-64.
-
(2001)
Development
, vol.128
, pp. 1253-1264
-
-
Brault, V.1
Moore, R.2
Kutsch, S.3
Ishibashi, M.4
Rowitch, D.H.5
McMahon, A.P.6
Sommer, L.7
Boussadia, O.8
Kemler, R.9
-
35
-
-
0035907041
-
Beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 2001; 105:533-45.
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
36
-
-
0037452932
-
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors
-
USA
-
Maretto S, Cordenonsi M, Dupont S, Braghetta P, Broccoli V, Hassan AB, Volpin D, Bressan GM, Piccolo S. Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci USA 2003; 100:3299-304.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 3299-3304
-
-
Maretto, S.1
Cordenonsi, M.2
Dupont, S.3
Braghetta, P.4
Broccoli, V.5
Hassan, A.B.6
Volpin, D.7
Bressan, G.M.8
Piccolo, S.9
-
37
-
-
0036166297
-
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
-
Staal FJ, Noort Mv M, Strous GJ, Clevers HC. Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin. EMBO Rep 2002; 3:63-8.
-
(2002)
EMBO Rep
, vol.3
, pp. 63-68
-
-
Staal, F.J.1
Noort, Mv.M.2
Strous, G.J.3
Clevers, H.C.4
-
38
-
-
0037422571
-
Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
-
USA
-
Fujino T, Asaba H, Kang MJ, Ikeda Y, Sone H, Takada S, Kim DH, Ioka RX, Ono M, Tomoyori H, Okubo M, Murase T, Kamataki A, Yamamoto J, Magoori K, Takahashi S, Miyamoto Y, Oishi H, Nose M, Okazaki M, Usui S, Imaizumi K, Yanagisawa M, Sakai J, Yamamoto TT. Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. Proc Natl Acad Sci USA 2003; 100:229-34.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 229-234
-
-
Fujino, T.1
Asaba, H.2
Kang, M.J.3
Ikeda, Y.4
Sone, H.5
Takada, S.6
Kim, D.H.7
Ioka, R.X.8
Ono, M.9
Tomoyori, H.10
Okubo, M.11
Murase, T.12
Kamataki, A.13
Yamamoto, J.14
Magoori, K.15
Takahashi, S.16
Miyamoto, Y.17
Oishi, H.18
Nose, M.19
Okazaki, M.20
Usui, S.21
Imaizumi, K.22
Yanagisawa, M.23
Sakai, J.24
Yamamoto, T.T.25
more..
-
39
-
-
0027385108
-
Beta-cell hypersensitivity for glucose precedes loss of glucose-induced insulin secretion in 90% pancreatectomized rats
-
Leahy JL, Bumbalo LM, Chen C. Beta-cell hypersensitivity for glucose precedes loss of glucose-induced insulin secretion in 90% pancreatectomized rats. Diabetologia 1993; 36:1238-44.
-
(1993)
Diabetologia
, vol.36
, pp. 1238-1244
-
-
Leahy, J.L.1
Bumbalo, L.M.2
Chen, C.3
-
40
-
-
0020636495
-
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release
-
Bonner-Weir S, Trent DF, Weir GC. Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 1983; 71:1544-53.
-
(1983)
J Clin Invest
, vol.71
, pp. 1544-1553
-
-
Bonner-Weir, S.1
Trent, D.F.2
Weir, G.C.3
-
42
-
-
27744517439
-
Wnt5 signaling in vertebrate pancreas development
-
Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC. Wnt5 signaling in vertebrate pancreas development. BMC Biol 2005; 3:23.
-
(2005)
BMC Biol
, vol.3
, pp. 23
-
-
Kim, H.J.1
Schleiffarth, J.R.2
Jessurun, J.3
Sumanas, S.4
Petryk, A.5
Lin, S.6
Ekker, S.C.7
-
43
-
-
4644231786
-
Wnt-independent beta-catenin transactivation in tumor development
-
Lu Z, Hunter T. Wnt-independent beta-catenin transactivation in tumor development. Cell Cycle 2004; 3:571-3.
-
(2004)
Cell Cycle
, vol.3
, pp. 571-573
-
-
Lu, Z.1
Hunter, T.2
|