Investigation of the dermal sensitization potential of various essential oils in the local lymph node assay

Food and Chemical Toxicology

Volumn 44, Issue 5, 2006, Pages 739-746

  Lalko, J ^a   Api, A M ^a  

^a RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS   (United States)

Author keywords

Essential oils; Fragrance materials; Local lymph node assay; Potency; Skin sensitization

Indexed keywords

ALCOHOL; CITRAL; CITRONELLAL; CLOVE OIL; ESSENTIAL OIL; EUGENOL; FRAGRANCE; GERANIOL; PHTHALIC ACID DIETHYL ESTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSAY; BASIL; CELL PROLIFERATION; CONTROLLED STUDY; CYMBOPOGON CITRATUS; DRUG EFFECT; FEMALE; GERANIUM; LITSEA; LYMPH NODE; MOUSE; NONHUMAN; SKIN SENSITIZATION;

ADMINISTRATION, TOPICAL; ALLERGENS; ANIMALS; BIOLOGICAL ASSAY; DERMATITIS, ALLERGIC CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; EUGENOL; FEMALE; HUMANS; LYMPH NODES; MICE; MICE, INBRED CBA; MONOTERPENES; OILS, VOLATILE; PERFUME; TERPENES; VOLATILIZATION;

ANIMALIA; CITRONELLA; CYMBOPOGON CITRATUS; LITSEA; LITSEA CUBEBA; OCIMUM BASILICUM; SYZYGIUM AROMATICUM;

EID: 33645236957     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.10.006     Document Type: Article

References (59)

1. A.M. Api Quenching of citral, cinnamaldehyde and phenylacetaldehyde sensitization in human repeated insult patch tests Contact Dermatitis 42 Suppl. 2 2000 40
2. A.M. Api Sensitization methodology and primary prevention of the research institute for fragrance materials Dermatology 205 2002 84 87
3. A.M. Api, and D. Isola Quenching of citral sensitization demonstrated in a human repeated insult patch test Contact Dermatitis 46 Suppl. 4 2000 37
4. S. Arctander Perfume and Flavor Materials of Natural Origin 1960 Steffen Arctander publisher Montclair, New Jersey
5. D. Basketter Quenching: Fact or fiction? Contact Dermatitis 43 5 2000 253 258
6. D.A. Basketter, and P. Cadby Reproducible prediction of contact allergenic potency using the local lymph node assay Contact Dermatitis 50 1 2004 15 17
7. D.A. Basketter, L.J. Lea, A. Dickens, D. Briggs, I. Pate, R. Dearman, and I. Kimber A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses Journal of Applied Toxicology 19 1999 261 266
8. D.A. Basketter, L. Blaikie, R.J. Dearman, I. Kimber, C.A. Ryan, G.F. Gerberick, P. Harvey, P. Evans, I.R. White, and R.J.G. Rycroft Use of the local lymph node assay for estimation of relative contact allergenic potential Contact Dermatitis 42 2000 344 348
9. D.A. Basketter, Z.M. Wright, N.R. Colson, G.Y. Patlewicz, and C.K. Smith-Pease Investigation of the skin sensitizing activity of linalool Contact Dermatitis 47 3 2002 161 164
10. D. Basketter, C. Clapp, B. Safford, D. Jefferies, I. Kimber, R. Dearman, C. Ryan, and F. Gerberick Correlation of LLNA and human skin sensitization thresholds The Toxicologist 84 S-1 2005 246
11. D.A. Basketter, K.E. Andersen, C. Liden, H. Van Loveren, A. Boman, I. Kimber, K. Alanko, and E. Berggren Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation Contact Dermatitis 52 1 2005 39 43
12. P.A. Cadby, W.R. Troy, and M.G.H Vey Consumer exposure to fragrance ingredients: providing estimates for safety evaluation Regulatory Toxicology and Pharmacology 36 2002 246 252
13. J. Cocchiara, C.S. Letizia, J. Lalko, A. Lapczynski, and A.M. Api Fragrance material review on cinnamaldehyde Food and Chemical Toxicology 43 6 2004 867 923
14. R.J. Dearman, Z.M. Wright, D.A. Basketter, C.A. Ryan, G.F. Gerberick, and I. Kimber The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay Contact Dermatitis 44 6 2001 357 361
15. ECVAM (European Centre for the Validation of Alternative Methods) Statement on the validity of the local lymph node assay for skin sensitization testing ATLA 28 2000 365 367
16. FMA (Fragrance Materials Association) Analytical Procedure 30: Peroxide Value 2002 Fragrance Materials Association Washington, DC
17. G.F. Gerberick, C.A. Ryan, I. Kimber, R.J. Dearman, L.J. Lea, and D.A. Basketter Local lymph node assay: validation for regulatory purposes American Journal of Contact Dermatitis 11 2000 3 18
18. G.F. Gerberick, M.K. Robinson, S.P. Felter, I.R. White, and D.A. Basketter Understanding fragrance allergy using an exposure-based risk assessment approach Contact Dermatitis 45 6 2001 333 340
19. G.F. Gerberick, M.K. Robinson, C.A. Ryan, R.J. Dearman, I. Kimber, D.A. Basketter, Z. Wright, and J.G. Marks Contact allergenic potency: correlation of human and local lymph node assay data American Journal of Contact Dermatitis 12 3 2001 156 161
20. Home Office Guidance on the Operation of the Animals (Scientific Procedures) Act, 1986 2000 Her Majesty's Stationary Office [H.M.S.O] London
21. IFRA (International Fragrance Association) Code of Practice, Standard on Cinnamaldehyde 2003 International Fragrance Association Brussels
22. A.-T. Karlberg, K. Magnusson, and U. Nilsson Air oxidation of d-limonene (the citrus solvent) creates potent allergens Contact Dermatitis 26 5 1992 332 340
23. A-T. Karlberg, A.-M. Nilsson, K. Luthman, and J.L. Nilsson Structural analogues inhibit the sensitizing capacity of carvone Acta Dermato-Venereologica 81 6 2001 398 402
24. I. Kimber, and D. Basketter The murine local lymph node assay: a commentary on collaborative studies and new directions Food and Chemical Toxicology 30 1992 165 169
25. I. Kimber, R.J. Dearman, E.W. Scholes, and D.A. Basketter The local lymph node assay: developments and applications Toxicology 93 1 1994 13 31
26. A.M. Kligman The identification of contact allergens by human assay. II. Factors influencing the induction and measurement of allergic contact dermatitis Journal of Investigative Dermatology 47 1966 375 392
27. A.M. Kligman, and W. Epstein Updating the maximization test for identifying contact allergens Contact Dermatitis 1 1975 231 239
28. J. Lalko, and A.M. Api Potency estimations for several fragrance materials in the local lymph node assay and their correlation to human studies The Toxicologist 84 S-1 2005 246
29. J. Lalko, D. Isola, and A.M. Api Ethanol and diethyl phthalate: vehicle effects in the local lymph node assay International Journal of Toxicology 23 3 2004 171 177
30. B.M. Lawrence Progress in Essential oils 1976-1978 1979 Allured Publishing Corporation Wheaton, IL
31. B.M. Lawrence Progress in Essential oils 1978 1979 Allured Publishing Corporation Wheaton, IL
32. B.M. Lawrence Progress in Essential oils 1979-1980 1981 Allured Publishing Corporation Wheaton, IL
33. B.M. Lawrence Progress in Essential oils 1981-1987 1989 Allured Publishing Corporation Wheaton, IL
34. B.M. Lawrence Progress in Essential oils 1988-1991 1993 Allured Publishing Corporation Carol Stream, IL
35. B.M. Lawrence Progress in Essential oils 1992-1994 1995 Allured Publishing Corporation Carol Stream, IL
36. B.M. Lawrence Progress in Essential oils 1995-2000 2003 Allured Publishing Corporation Carol Stream, IL
37. B.M. Lawrence Progress in essential oils: basil oil Perfumer and Flavorist 30 September 2004 80 90
38. L.J. Lea, E. Warbrick, R. Dearman, I. Kimber, and D. Basketter The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay American Journal of Contact Dermatitis 10 1999 213 218
39. S.E. Loveless, G.S. Ladics, G.F. Gerberick, C.A. Ryan, D.A. Basketter, E.W. Scholes, R.V. House, J. Hilton, R.J. Dearman, and I. Kimber Further evaluation of the local lymph node assay in the final phase of an international collaborative trial Toxicology 108 1-2 1996 141 152
40. F.N. Marzulli, and H.I. Maibach Contact allergy: predictive testing in humans F.N. Marzulli H.I. Maibach Advances in Modern Toxicology. Dermatotoxicology and Pharmacology vol. 4 1977 Hemisphere London 353 371
41. McNamee, P.M., Gilpin, D.A., Robinson, M.K., Gerberick, G.F., in press. A review of critical factors in the conduct and interpretation of the human repeat insult patch test. Contact Dermatitis.
42. NIH (National Institutes of Health) 1999. The murine local lymph node assay: a test method for assessing the allergic contact dermatitis potential of chemicals/compounds. Publication No: 99-4494. Bethesda, Maryland, NIH.
43. A.-M. Nilsson, E. Gäfvert, L. Salvador, K. Luthman, M. Bruze, B. Gruvberger, J.L.G. Nilsson, and A.-T. Karlberg Mechanism of the antigen formation of carvone and related alpha,beta-unsaturated ketones Contact Dermatitis 44 2001 347 356
44. A.-.M. Nilsson, C. Jonsson, K. Luthman, J.L.G. Nilsson, and A.-.T. Karlberg Inhibition of the sensitising effects of carvone by the addition of non-allergenic compounds Acta Dermato-Venereologica 84 2004 99 105
45. OECD (Organization for Economic Co-Operation and Development) Skin Sensitization: Local Lymph Node Assay. Guideline reference 429 2002 OECD Paris
46. D.L.J. Opdyke Inhibition of sensitization reactions induced by certain aldehydes Food and Cosmetics Toxicology 14 3 1976 197 198
47. RIFM (Research Institute for Fragrance Materials, Inc.) 1971. Appraisal of sensitizing powers by maximization testing in humans. Report number 1805, September 27, RIFM, Woodcliff Lake, NJ, USA.
48. RIFM (Research Institute for Fragrance Materials, Inc.) 1972a. The contact-sensitization potential of fragrance materials by maximization testing in humans. Report number 1804, February 18, RIFM, Woodcliff Lake, NJ, USA.
49. RIFM (Research Institute for Fragrance Materials, Inc.) 1972b. The contact-sensitization potential of fragrance materials by maximization testing in humans. Report number 1804, March 14, RIFM, Woodcliff Lake, NJ, USA.
50. RIFM (Research Institute for Fragrance Materials, Inc.) 1973. Report on human maximization studies, Report number 1803, July 17, RIFM, Woodcliff Lake, NJ, USA.
51. RIFM (Research Institute for Fragrance Materials, Inc.) 1974a. Report on human maximization studies. Report number 1801, August 19, RIFM, Woodcliff Lake, NJ, USA.
52. RIFM (Research Institute for Fragrance Materials, Inc.) 1974b. Report on human maximization studies. Report number 1779, October 18, RIFM, Woodcliff Lake, NJ, USA.
53. RIFM (Research Institute for Fragrance Materials, Inc.) 1976. Report on human maximization studies. Report number 1796, October 8, RIFM, Woodcliff Lake, NJ, USA.
54. RIFM (Research Institute for Fragrance Materials, Inc.) 2004a. Citronellal: local lymph node assay. Unpublished report from IFF. Report number 47817, RIFM, Woodcliff Lake, NJ, USA.
55. RIFM (Research Institute for Fragrance Materials, Inc.) 2004b. Local lymph node assay on d-Limonene. Report number 45754, RIFM, Woodcliff Lake, NJ, USA.
56. K. Schneider, and Z. Akkan Quantitative relationship between the local lymph node assay and human skin sensitization assays Regulatory Toxicology and Pharmacology 39 3 2004 245 255
57. M. Skold, A. Borje, E. Harambasic, and A.-T. Karlberg Contact allergens formed on air exposure of linalool. Identification and quantification of primary and secondary oxidation products and the effect on skin sensitization Chemical Research in Toxicology 17 12 2004 1697 1705
58. E.V. Warbrick, R.J. Dearman, L.J. Lea, D. Basketter, and I. Kimber Local lymph node assay responses to paraphenylenediamine intra- and inter-laboratory evaluations Journal of Applied Toxicology 19 1999 255 260
59. E. Warbrick, R. Dearman, D. Basketter, and I. Kimber Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/ methylisothiazolinone: an analysis using the local lymph node assay Contact Dermatitis 41 1999 325 329