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Volumn , Issue , 2007, Pages 123-131

Cytokines and Inflammatory Recruitment in NASH: Experimental and Human Studies

Author keywords

Immune system; Insulin resistance; Nonalcoholic steatohepatitis (NASH); Norepinephrine (NE); Pathogenic mechanisms

Indexed keywords


EID: 33645218405     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470987438.ch10     Document Type: Chapter
Times cited : (5)

References (44)
  • 1
    • 0019152816 scopus 로고
    • Non-alcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J, Viggiano RT, McGill DB. Non-alcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980; 55: 342-8.
    • (1980) Mayo Clin Proc. , vol.55 , pp. 342-348
    • Ludwig, J.1    Viggiano, R.T.2    McGill, D.B.3
  • 2
    • 0029121402 scopus 로고
    • Cytokine gene expression by Kupffer cells isolated from ethanol-fed rats
    • Kamimura S, Tsukamoto H. Cytokine gene expression by Kupffer cells isolated from ethanol-fed rats. Hepatology 1995; 22: 1304-9.
    • (1995) Hepatology , vol.22 , pp. 1304-1309
    • Kamimura, S.1    Tsukamoto, H.2
  • 4
    • 0024587645 scopus 로고
    • Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
    • McClain CJ, Cohen DA. Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 1989; 9: 349-51.
    • (1989) Hepatology , vol.9 , pp. 349-351
    • McClain, C.J.1    Cohen, D.A.2
  • 5
    • 0026655214 scopus 로고
    • Increased plasma interleukin-6 activity in alcoholic hepatitis
    • Hill D, Marsano L, Cohen D et al. Increased plasma interleukin-6 activity in alcoholic hepatitis. J Lab Clin Med 1992; 119: 507-12.
    • (1992) J Lab Clin Med. , vol.119 , pp. 507-512
    • Hill, D.1    Marsano, L.2    Cohen, D.3
  • 6
    • 0030716183 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor-a attenuates hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
    • Iimuro Y, Gallucci RM, Luster MI, Kono H, Thurman RG. Antibodies to tumor necrosis factor-a attenuates hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997; 26: 1530-7.
    • (1997) Hepatology , vol.26 , pp. 1530-1537
    • Iimuro, Y.1    Gallucci, R.M.2    Luster, M.I.3    Kono, H.4    Thurman, R.G.5
  • 7
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi Y, Moore LE, Bradford BU, Gao W, Thurman RG. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995; 108: 218-24.
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 8
    • 0028220726 scopus 로고
    • Lactobacillus feeding reduces endotoxemia and severity of experimentalalcoholic liver disease
    • Nanji AA, Khettry U, Sadrzadeh SM. Lactobacillus feeding reduces endotoxemia and severity of experimentalalcoholic liver disease. Proc Soc Exp Biol Med 1994; 205: 243-7.
    • (1994) Proc Soc Exp Biol Med. , vol.205 , pp. 243-247
    • Nanji, A.A.1    Khettry, U.2    Sadrzadeh, S.M.3
  • 9
    • 0025260531 scopus 로고
    • Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors
    • Wanless IR, Lentz JS. Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. Hepatology 1990; 12: 1106-10.
    • (1990) Hepatology , vol.12 , pp. 1106-1110
    • Wanless, I.R.1    Lentz, J.S.2
  • 11
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue: regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • Kern PA, Saghizaheh M, Ong JM et al. The expression of tumor necrosis factor in human adipose tissue: regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995; 95: 2111-9.
    • (1995) J Clin Invest. , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizaheh, M.2    Ong, J.M.3
  • 12
    • 0036788244 scopus 로고    scopus 로고
    • Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system
    • Li Z, Lin HZ, Yang SQ, Diehl AM. Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system. Gastroenterology 2002; 123: 1304-10.
    • (2002) Gastroenterology , vol.123 , pp. 1304-1310
    • Li, Z.1    Lin, H.Z.2    Yang, S.Q.3    Diehl, A.M.4
  • 13
    • 0037078969 scopus 로고    scopus 로고
    • Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events
    • Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002; 347: 1557-65.
    • (2002) N Engl J Med. , vol.347 , pp. 1557-1565
    • Ridker, P.M.1    Rifai, N.2    Rose, L.3    Buring, J.E.4    Cook, N.R.5
  • 14
    • 0035183475 scopus 로고    scopus 로고
    • Gene expression of tumor necrosis factor a and TNF-receptors, p55 and p75, in non-alcoholic steatohepatitis patients
    • Crespo J, Cayon A, Fernandez-Gil P et al. Gene expression of tumor necrosis factor a and TNF-receptors, p55 and p75, in non-alcoholic steatohepatitis patients. Hepatology 2001; 34: 1158-63.
    • (2001) Hepatology , vol.34 , pp. 1158-1163
    • Crespo, J.1    Cayon, A.2    Fernandez-Gil, P.3
  • 15
    • 0036165809 scopus 로고    scopus 로고
    • Tumor necrosis factor a promoter polymorphisms and insulin resistance in non-alcoholic fatty liver disease
    • Valenti L, Fracanzani AL, Dongiovanni P et al. Tumor necrosis factor a promoter polymorphisms and insulin resistance in non-alcoholic fatty liver disease. Gastroenterology 2002; 122: 274-80.
    • (2002) Gastroenterology , vol.122 , pp. 274-280
    • Valenti, L.1    Fracanzani, A.L.2    Dongiovanni, P.3
  • 16
    • 0035125052 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor a in the pathogenesis of non-alcoholic steatohepatitis
    • Wigg AJ, Roberts-Thomson IC, Dymock RB et al. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor a in the pathogenesis of non-alcoholic steatohepatitis. Gut 2001; 48: 206-11.
    • (2001) Gut. , vol.48 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thomson, I.C.2    Dymock, R.B.3
  • 17
    • 0036677340 scopus 로고    scopus 로고
    • Gut-liver axis: a new point of attack to treat chronic liver damage?
    • Loguercio C, DeSimone T, Federico A et al. Gut-liver axis: a new point of attack to treat chronic liver damage? Am J Gastroenterol 2002; 97: 2144-6.
    • (2002) Am J Gastroenterol. , vol.97 , pp. 2144-2146
    • Loguercio, C.1    DeSimone, T.2    Federico, A.3
  • 18
    • 0035041058 scopus 로고    scopus 로고
    • Promoter polymorphism of the CD14 endotoxin receptor gene as a risk factor for alcoholic liver disease
    • Jarvelainen HA, Orpana A, Perola M et al. Promoter polymorphism of the CD14 endotoxin receptor gene as a risk factor for alcoholic liver disease. Hepatology 2001; 33: 1148-53.
    • (2001) Hepatology , vol.33 , pp. 1148-1153
    • Jarvelainen, H.A.1    Orpana, A.2    Perola, M.3
  • 19
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang Y, Proenca R, Maffei M et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-32.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3
  • 20
    • 0001513966 scopus 로고    scopus 로고
    • Obesity increases sensitivity to endotoxin liver injury: implications for pathogenesis of steatohepatitis
    • Yang SQ, Lin HZ, Lane MD, Clemens M, Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for pathogenesis of steatohepatitis. Proc Natl Acad Sci USA 1997; 94: 2557-62.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2557-2562
    • Yang, S.Q.1    Lin, H.Z.2    Lane, M.D.3    Clemens, M.4    Diehl, A.M.5
  • 21
    • 0035195887 scopus 로고    scopus 로고
    • Leptin regulation of the immune response and the immunodeficiency of malnutrition
    • Faggioni R, Feingold KR, Grunfeld C. Leptin regulation of the immune response and the immunodeficiency of malnutrition. FASEB J 2001; 15: 2565-71.
    • (2001) FASEB J. , vol.15 , pp. 2565-2571
    • Faggioni, R.1    Feingold, K.R.2    Grunfeld, C.3
  • 22
    • 0035887941 scopus 로고    scopus 로고
    • High-dose leptin activates human leukocytes via receptor expression on monocytes
    • Zarkesh-Esfahani H, Pockley G, Metcalfe RA et al. High-dose leptin activates human leukocytes via receptor expression on monocytes. J Immunol 2001; 167: 4593-9.
    • (2001) J Immunol. , vol.167 , pp. 4593-4599
    • Zarkesh-Esfahani, H.1    Pockley, G.2    Metcalfe, R.A.3
  • 23
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
    • Lord GM, Matarese G, Howard JK et al. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 1998; 394: 897-901.
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3
  • 24
    • 0037241113 scopus 로고    scopus 로고
    • Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses
    • Sanna V, Di Giacomo A, La Cava A et al. Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses. J Clin Invest 2003; 111: 241-50.
    • (2003) J Clin Invest. , vol.111 , pp. 241-250
    • Sanna, V.1    Di Giacomo, A.2    La Cava, A.3
  • 25
    • 0031965266 scopus 로고    scopus 로고
    • Leptin regulates proinflammatory immune responses
    • Loffreda S, Yang SQ, Lin HZ et al. Leptin regulates proinflammatory immune responses. FASEB J 1998; 12: 57-65.
    • (1998) FASEB J. , vol.12 , pp. 57-65
    • Loffreda, S.1    Yang, S.Q.2    Lin, H.Z.3
  • 26
    • 0032741972 scopus 로고    scopus 로고
    • Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice
    • Howard JK, Lord GM, Matarese G et al. Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice. J Clin Invest 1999; 104: 1051-9.
    • (1999) J Clin Invest. , vol.104 , pp. 1051-1059
    • Howard, J.K.1    Lord, G.M.2    Matarese, G.3
  • 27
    • 0034005303 scopus 로고    scopus 로고
    • Altered hepatic lymphocyte subpopulations in obesity-related fatty livers
    • Guebre-Xabier M, Yang SQ, Lin HZ et al. Altered hepatic lymphocyte subpopulations in obesity-related fatty livers. Hepatology 1999; 31: 633-40.
    • (1999) Hepatology , vol.31 , pp. 633-640
    • Guebre-Xabier, M.1    Yang, S.Q.2    Lin, H.Z.3
  • 28
    • 0031179507 scopus 로고    scopus 로고
    • Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type 1 T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells
    • Matsui K, Yoshimoto T, Tsutsui H et al. Propionibacterium acnes treatment diminishes CD4+ NK1.1+ T cells but induces type 1 T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells. J Immunol 1997; 159: 97-106.
    • (1997) J Immunol. , vol.159 , pp. 97-106
    • Matsui, K.1    Yoshimoto, T.2    Tsutsui, H.3
  • 29
    • 0033761530 scopus 로고    scopus 로고
    • Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice
    • Makimura H, Mizuno TM, Roberts J et al. Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice. Diabetes 2000; 49: 1917-23.
    • (2000) Diabetes , vol.49 , pp. 1917-1923
    • Makimura, H.1    Mizuno, T.M.2    Roberts, J.3
  • 30
    • 12644315192 scopus 로고
    • Reduced norepinephrine turnover in brown adipose tissue of ob/ob mice
    • Knehans AW, Romsos DR. Reduced norepinephrine turnover in brown adipose tissue of ob/ob mice. Am J Physiol 1982; 242: E253-61.
    • (1982) Am J Physiol. , vol.242 , pp. E253-E261
    • Knehans, A.W.1    Romsos, D.R.2
  • 31
    • 0034776770 scopus 로고    scopus 로고
    • Selective deletion of leptin receptor in neurons leads to obesity
    • Cohen P, Zhao C, Cai X et al. Selective deletion of leptin receptor in neurons leads to obesity. J Clin Invest 2001; 108: 1113-21.
    • (2001) J Clin Invest. , vol.108 , pp. 1113-1121
    • Cohen, P.1    Zhao, C.2    Cai, X.3
  • 32
    • 0028329184 scopus 로고
    • Endogenous norepinephrine regulates tumor necrosis factor-a production from macrophages in vitro
    • Spengler RN, Chensue SW, Giacherio DA, Blenk N, Kunkel SL. Endogenous norepinephrine regulates tumor necrosis factor-a production from macrophages in vitro. J Immunol 1994; 152: 3024-31.
    • (1994) J Immunol. , vol.152 , pp. 3024-3031
    • Spengler, R.N.1    Chensue, S.W.2    Giacherio, D.A.3    Blenk, N.4    Kunkel, S.L.5
  • 33
    • 0033198132 scopus 로고    scopus 로고
    • Norepinephrine-mediated inhibition of antitumor cytotoxic T lymphocyte generation involves a β-adrenergic receptor mechanism and decreased TNF-a gene expression
    • Kalinichenko VV, Mokyr MB, Graf LH Jr, Cohen RL, Chambers DA. Norepinephrine-mediated inhibition of antitumor cytotoxic T lymphocyte generation involves a β-adrenergic receptor mechanism and decreased TNF-a gene expression. J Immunol 1999; 163: 2492-9.
    • (1999) J Immunol. , vol.163 , pp. 2492-2499
    • Kalinichenko, V.V.1    Mokyr, M.B.2    Graf L.H, Jr.3    Cohen, R.L.4    Chambers, D.A.5
  • 34
    • 0033669568 scopus 로고    scopus 로고
    • Neuroendocrine regulation of IL-12 and TNF-a/IL-10 balance: clinical implications
    • Elenkov IJ, Chrousos GP, Wilder RL. Neuroendocrine regulation of IL-12 and TNF-a/IL-10 balance: clinical implications. Ann NY Acad Sci 2000; 917: 94-105.
    • (2000) Ann NY Acad Sci. , vol.917 , pp. 94-105
    • Elenkov, I.J.1    Chrousos, G.P.2    Wilder, R.L.3
  • 35
    • 0035958703 scopus 로고    scopus 로고
    • The role of Kupffer cell 2- adrenoceptors in norepinephrine-induced TNF-a production
    • Zhou M, Yang S, Koo DJ et al. The role of Kupffer cell 2- adrenoceptors in norepinephrine-induced TNF-a production. Biochim Biophys Acta 2001; 1537: 49-57.
    • (2001) Biochim Biophys Acta , vol.1537 , pp. 49-57
    • Zhou, M.1    Yang, S.2    Koo, D.J.3
  • 36
    • 0034106520 scopus 로고    scopus 로고
    • Intensive expansion of natural killer T cells in the early phase of hepatocyte regeneration after partial hepatectomy in mice and its association with sympathetic nerve activation
    • Minagawa M, Oya H, Yamamoto S et al. Intensive expansion of natural killer T cells in the early phase of hepatocyte regeneration after partial hepatectomy in mice and its association with sympathetic nerve activation. Hepatology 2000; 31: 907-15.
    • (2000) Hepatology , vol.31 , pp. 907-915
    • Minagawa, M.1    Oya, H.2    Yamamoto, S.3
  • 37
    • 0036207887 scopus 로고    scopus 로고
    • The resistance of Pacnes-primed interferon-y-deficient mice to low-dose lipopolysaccharide-induced acute liver injury
    • Shimizu Y, Margenthaler JA, Landeros K et al. The resistance of P. acnes-primed interferon-y-deficient mice to low-dose lipopolysaccharide-induced acute liver injury. Hepatology 2002; 35: 805-14.
    • (2002) Hepatology , vol.35 , pp. 805-814
    • Shimizu, Y.1    Margenthaler, J.A.2    Landeros, K.3
  • 38
    • 0037153158 scopus 로고    scopus 로고
    • A central role for JNK in obesity and insulin resistance
    • Hirosumi J, Tuncman G, Chang L et al. A central role for JNK in obesity and insulin resistance. Nature 2002; 420: 333-6.
    • (2002) Nature , vol.420 , pp. 333-336
    • Hirosumi, J.1    Tuncman, G.2    Chang, L.3
  • 39
    • 0034903710 scopus 로고    scopus 로고
    • Prevention of fat- induced insulin resistance by salicylate
    • Kim JK, Kim YJ, Fillmore JJ et al. Prevention of fat- induced insulin resistance by salicylate. J Clin Invest 2001; 108: 437-46.
    • (2001) J Clin Invest. , vol.108 , pp. 437-446
    • Kim, J.K.1    Kim, Y.J.2    Fillmore, J.J.3
  • 40
    • 0035979775 scopus 로고    scopus 로고
    • Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKK-p
    • Yuan M, Konstantopoulos N, Lee J et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKK-p. Science 2001; 293: 1673-7.
    • (2001) Science , vol.293 , pp. 1673-1677
    • Yuan, M.1    Konstantopoulos, N.2    Lee, J.3
  • 41
    • 0033764665 scopus 로고    scopus 로고
    • Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NK-kB
    • Aggarwal BB. Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NK-kB. Ann Rheum Dis 2000; 59 (Suppl. 1): I6 -I16.
    • (2000) Ann Rheum Dis. , vol.59 , pp. I6-I16
    • Aggarwal, B.B.1
  • 42
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin-resistance in mice lacking TNF-a function
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin-resistance in mice lacking TNF-a function. Nature 1997; 389: 610-4.
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 43
    • 0037309589 scopus 로고    scopus 로고
    • Probiotics and antibodies to TNF inhibit inflammatory activity and improve non-alcoholic fatty liver disease
    • Li Z, Yang S, Lin H et al. Probiotics and antibodies to TNF inhibit inflammatory activity and improve non-alcoholic fatty liver disease. Hepatology 2003; 37: 343-50.
    • (2003) Hepatology , vol.37 , pp. 343-350
    • Li, Z.1    Yang, S.2    Lin, H.3
  • 44
    • 0035078484 scopus 로고    scopus 로고
    • Etiopathogenesis of non-alcoholic steatohepatitis
    • Chitturi S, Farrell GC. Etiopathogenesis of non-alcoholic steatohepatitis. Semin Liver Dis 2001; 21: 27-41.
    • (2001) Semin Liver Dis. , vol.21 , pp. 27-41
    • Chitturi, S.1    Farrell, G.C.2


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