Involvement of PKC, p38 MAPK and AP-2 in IL-1β-induced expression of cyclooxygenase-2 in human pulmonary epithelial cells

Respirology

Volumn 11, Issue 1, 2006, Pages 18-23

  Chen, Ping ^a,c   Cai, Ying ^a   Yang, Zhi Gang ^a   Zhou, Rui ^a   Zhang, Guang Shen ^a   Domann, Frederick ^b   Fang, Xiang ^b  

^a Central South University   (China)

^b UNIVERSITY OF IOWA   (United States)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Activator protein 2; Cyclooxygenase 2; Mitogen activated and extracellular regulated kinase kinase 1; Mitogen activated protein kinase; Protein kinase C

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATOR PROTEIN 2; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ADENOVIRUS VECTOR; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL LINE, TUMOR; CYCLOOXYGENASE 2; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTERLEUKIN-1; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-2;

EID: 33645110040     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2006.00779.x     Document Type: Article

References (26)

1. Mitchell JA Larkin S Williams TJ Cyclooxgenase-2: regulation and relevance in inflammation BrJPharmacol 1995 50 1535 42
2. Vane JR Bakhle YS Botting RM Cyclooxgenase 1 and 2 AnnuRevPharmacolToxicol 1998 38 97 120
3. Chen P Hu S Yao J Moore SA Spector AA Fang X Induction of cyclooxygenase-2 by anandamine in cerebral microvascular endothelium MicrovascRes 2005 66 28 35
4. Fang X Chen P Moore SA The oxygen radical scavenger pyrrolidine dithiocarbamate enhances interleukin-1beta-induced cyclooxygenase-2 expression in cerebral microvascular smooth muscle cells MicrovascRes 2002 64 405 13
5. Profita M Sala A Bonanno A et al. Increased prostaglandin E2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia JAllergy ClinImmunol 2003 112 709 16
6. Xaubet A Roca-Ferrer J Pujols L et al. Cyclooxygenase-2 is up-regulated in lung parenchyma of chronic obstructive pulmonary disease and down-regulated in idiopathic pulmonary fibrosis Sarcoidosis VascDiffuse Lung Dis 2004 21 35 42
7. Nishizuka Y Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C Science 1992 258 607 14
8. Cohen MD Ciocca V Panettieri RA Jr. TGF-beta1 modulates human airway smooth-muscle cell proliferation induced by mitogens AmJRespirCell MolBiol 1997 16 85 90
9. Karin M Hunter T Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus CurrBiol 1995 5 747 57
10. Chung KF Cytokines in chronic obstructive pulmonary disease EurRespirJ 2001 18 Suppl. 50s 9s
11. Watkins DN Peroni DJ Lenzo JC Knight DA Garlepp MJ Thompson PJ Expression and localization of COX-2 in human airways and cultured airway epithelial cells EurRespirJ 1999 13 999 1007
12. Mitchell JA Belvisi MG Akarasereenont P et al. Induction of cyclooxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone BrJPharmacol 1994 113 1008 14
13. 2 release via mechanistically distinct processes BrJPharmacol 2000 130 1353 61
14. Fan XM Wong BC Lin MC et al. Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways JGastroenterolHepatol 2001 16 1098 104
15. Yang LL Liang YC Chang CW et al. Effects of sphondin, isolated from Heracleum, on IL-1beta-induced cyclooxygenase-2 expression in human pulmonary epithelial cells Life Sci 2002 72 199 213
16. Hilger-Eversheim K Moser M Schorle H Buettner R Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control Gene 2000 260 1 12
17. Appleby SB Ristimaki A Neilson K Narko K Hla T Structure of the human cyclo-oxygenase-2 gene BiochemJ 1994 302 723 7
18. Kirtikara K Raghow R Laulederkind SJ Goorha S Kanekura T Ballou LR Transcriptional regulation of cyclooxygenase-2 in human microvascular endothelial cell line, HMEC-1: control by the combinatorial actions of AP-2, NF-IL-6 and CRE elements MolCellBiochem 2000 203 41 51
19. Asano K Lilly CM Drazen JM Prostaglandin G/H synthase-2 is the constitutive and dominant isoform in cultured human lung epithelial cells AmJPhysiol 1996 271 L126 31
20. Rang SP Pang L Holland E Knox AJ Selectivity of cyclooxygenase inhibitors in human pulmonary epithelial and smooth muscle cells EurRespirJ 2000 15 751 6
21. Schmedtje JF Jr Ji YS Liu WL DuBois RN Runge MS Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells JBiolChem 1997 272 601 8
22. Crofford LJ Tan B McCarthy CJ Hla T Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes Arthritis Rheum 1997 40 226 36
23. Newton R Kuitert LM Bergmann M Adcock IM Barnes PJ Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta BiochemBiophysResCommun 1997 237 28 32
24. Schroer K Zhu Y Saunders MA et al. Obligatory role of cyclic adenosine monophosphate response element in cyclooxygenase-2 promoter induction and feedback regulation by inflammatory mediators Circulation 2002 105 2760 5
25. Oyama N Iwatsuki K Homma Y Kaneko F Induction of transcription factor AP-2 by inflammatory cytokines in human keratinocytes JInvestDermatol 1999 113 600 6
26. Suyama K Kabuyama Y Suzuki S et al. Induction of transcription factor AP-2 by cytokines and prostaglandins in cultured mesangial cells AmJNephrol 2001 21 307 14