Computational study of the fibril organization of polyglutamine repeats reveals a common motif identified in β-helices

Journal of Molecular Biology

Volumn 358, Issue 1, 2006, Pages 330-345

  Zanuy, David ^a   Gunasekaran, Kannan ^b   Lesk, Arthur M ^c   Nussinov, Ruth ^b,d  

^a UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^b SAIC FREDERICK INC   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Huntingtin protein; Polyglutamine repeats; Protofibril conformation; Structural analysis; helices

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; POLYGLUTAMINE;

AMINO ACID SEQUENCE; ARTICLE; FIBER; HYDROGEN BOND; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DATA BANK; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEOMICS; STRUCTURE ANALYSIS;

EID: 33645101164     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.01.070     Document Type: Article

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