Radical prostatectomy with positive surgical margins: How are patients managed?

BJU International

Volumn 97, Issue 3, 2006, Pages 445-450

  Thurairaja, Ramesh ^a   Osborn, Jonathan ^b   Mcfarlane, Jonathan ^c   Bahl, Amit ^a   Persad, Rajendra ^a  

^a BRISTOL ROYAL INFIRMARY   (United Kingdom)

^b WESTON GENERAL HOSPITAL   (United Kingdom)

^c ROYAL UNITED HOSPITAL   (United Kingdom)

Author keywords

Positive surgical margins; Radical prostatectomy

Indexed keywords

BICALUTAMIDE; GOSERELIN;

ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; DISEASE COURSE; DRUG EFFECT; ENDOSCOPIC SURGERY; HORMONAL THERAPY; HUMAN; INCISION; INTERMETHOD COMPARISON; LAPAROSCOPIC SURGERY; LYMPH NODE METASTASIS; METASTASIS; MULTIVARIATE ANALYSIS; ORCHIECTOMY; OUTCOME ASSESSMENT; PATIENT CARE; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CANCER; PROSTATE TUMOR; PROSTATECTOMY; RISK; RISK REDUCTION; ROBOTICS; SEMINAL VESICLE; SHORT SURVEY; SURGICAL ANATOMY; SURGICAL APPROACH; SURGICAL TECHNIQUE; TREATMENT OUTCOME; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR RECURRENCE;

HUMANS; LYMPH NODE EXCISION; MALE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM, RESIDUAL; PROSTATECTOMY; PROSTATIC NEOPLASMS; RISK FACTORS; SURVIVAL ANALYSIS;

EID: 33644996745     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2006.05997.x     Document Type: Short Survey

References (39)

1. Smith DS Catalona WJ Herschman JD Longitudinal screening for prostate cancer with prostate-specific antigen JAMA 1996 276 1309 15
2. Catalona WJ Smith DS 5-year tumor recurrence rates after anatomical radical retropubic prostatectomy for prostate cancer J Urol 1994 152 1837 42
3. Cheng L Darson ME Bergstralh EJ Slezak J Myers RP Bostwick DG Correlation of margin status and extraprostatic extension with progression of prostate carcinoma Cancer 1999 86 1775 82
4. Palisaar RJ Noldus J Graefen M Erbersdobler A Haese A Huland H Influence of nerve-sparing (NS) procedure during radical prostatectomy (RP) on margin status and biochemical failure Eur Urol 2005 47 176 84
5. Boccon-Gibod L Ravery V Vordos D Toublanc M Delmas V Boccon-Gibod L Radical prostatectomy for prostate cancer: the perineal approach increases the risk of surgically induced positive margins and capsular incisions J Urol 1998 160 1383 5
6. Epstein JI Sauvageot J Do close but negative margins in radical prostatectomy specimens increase the risk of postoperative progression? J Urol 1997 157 241 3
7. Freeland SJ Aronson WJ Presti JC et al. The Search Database Study Group. Should a positive surgical margin following radical prostatectomy be pathological stage T2 or T3? Results from the Search Database J Urol 2003 169 2142 6
8. Wieder JA Soloway MS Incidence, etiology, location, prevention and treatment of positive surgical margins after radical prostatectomy for prostate cancer J Urol 1998 160 299 315
9. Hull GW Rabbani F Abbas F Wheeler TM Kattan MW Scardino PT Cancer control with radical prostatectomy alone in 1,000 consecutive patients J Urol 2002 167 528 34
10. Ward JF Zincke H Bergstralh EJ Slezak JM Myers RP Blute ML The impact of surgical approach (nerve bundle preservation versus wide local excision) on surgical margins and biochemical recurrence following radical prostatectomy J Urol 2004 172 1328 32
11. Korman HJ Leu PB Huang RR Goldstein NS A centralized comparison of radical perineal and retropubic prostatectomy specimens: is there a difference according to the surgical approach? J Urol 2002 168 991 4
12. Erdogru T Teber D Frede T et al. Comparison of transperitoneal and extraperitoneal laproscopic radical prostatectomy using match-pair analysis Eur Urol 2004 46 312 20
13. Brown JA Garlitz C Gomella LG et al. Pathologic comparison of laproscopic versus open radical retropubic prostatectomy specimens Urology 2003 62 481 6
14. Salomon L Levrel O Anastasiadis AG et al. Outcome and complications of radical prostatectomy in patients with PSA <10ng/ml: comparison between the retropubic, perineal and laparoscopic approach Prostate Cancer Prostatic Dis 2002 5 285 90
15. Epstein JI Incidence and significance of positive margins in radical prostatectomy specimens Urol Clin North Am 1996 23 651 63
16. Hall GS Kramer CE Epstein JI Evaluation of radical prostatectomy specimens. A comparative analysis of sampling methods Am J Surg Pathol 1992 16 315 24
17. D'Amico AV Whittington R Malkowicz SB et al. A multivariate analysis of clinical and pathological factors that predict for prostate specific antigen failure after radical prostatectomy for prostate cancer J Urol 1995 154 131 8
18. Sofer M Hamilton-Nelson KL Civantos F Soloway MS Positive surgical margins after radical retropubic prostatectomy: the influence of site and number on progression J Urol 2002 167 2453 6
19. Obek C Sadek S Lai S Civantos F Rubinowicz D Soloway MS Positive surgical margins with radical retropubic prostatectomy: anatomic site-specific pathologic analysis and impact on prognosis Urology 1999 54 682 8
20. Salomon L Anastasiadis AG Levrel O et al. Location of positive surgical margins after retropubic, perineal and laproscopic radical prostatectomy for organ-confined prostate cancer Urology 2003 61 386 90
21. Epstein JI Pizov G Walsh PC Correlation of pathologic findings with progression after radical retropubic prostatectomy Cancer 1993 71 3582 93
22. Grossfeld GD Chang JJ Broering JM et al. Impact of positive surgical margins on prostate cancer recurrence and the use of secondary cancer treatment: data from the CaPSURE database J Urol 2000 163 1171 7
23. Blute ML Bostwick DG Bergstralh EJ et al. Anatomic site-specific positive margins in organ-confined prostate cancer and its impact on outcome after radical prostatectomy Urology 1997 50 733 9
24. Shuford MD Cookson MS Chang SS et al. Adverse prognostic significance of capsular incision with radical retropubic prostatectomy J Urol 2004 172 119 23
25. Ohori M Abbas F Wheeler TM Kattan MW Scardino PT Lerner SP Pathologic features and prognostic significance of prostate cancer in apical section determined by whole mount histology J Urol 1999 161 500 4
26. Walsh PC Marschke P Ricker D Burnett AL Use of intraoperative video documentation to improve sexual function after radical retropubic prostatectomy Urology 2000 55 62 7
27. Touijer K Kuroiwa K Saranchuk JW et al. Quality improvement in laproscopic radical prostatectomy for pT2 prostate cancer: impact of video documentation review on positive surgical margin J Urol 2005 173 765 8
28. Ahlering TE Eichel L Edwards RA Lee DI Skarecky DW Robotic radical prostatectomy: a technique to reduce pT2 positive margins Urology 2004 64 1224 8
29. Isorna Martinez de la Riva S Belon Lopez-Tomasety J Marrero Dominguez R Alvarez Cruz E Santamaria Blanco P [Radical protatectomy as monotherapy for locally advanced prostate cancer (T3a): 12 years follow-up] Arch Esp Urol 2004 57 679 92
30. Connolly JA Shinohara K Presti JC Carroll PR Local recurrence after radical prostatectomy: characteristics in size, location, and relationship to prostate-specific antigen and surgical margins Urology 1996 47 225 31
31. Di Blasio CJ Fearn P Seo HS et al. Association between number of lymph nodes removed and freedom from disease progression in patients receiving pelvic lymph node dissection during radical prostatectomy J Urol 2003 169 456
32. Stephenson AJ Shariat SF Zelefsky MJ et al. Salvage radiotherapy for recurrent prostate cancer after radical prostatectomy JAMA 2004 291 1325 32
33. Eggener SE Roehl KA Smith ND Antenor JA Han M Catalona WJ Contemporary survival results and the role of radiation therapy in patients with node negative seminal vesicle invasion following radical prostatectomy J Urol 2005 173 1150 5
34. Bolla M Van Poppel P Van Cangh K et al. Does post-operative radiotherapy (P-RXT) after radical prostatectomy (Px) improve progression-free survival (PFS) in pT3N0 prostate cancer (PC)? (EORTC 22911) J Clin Oncol 2004 22 4504
35. Messing EM Manola J Sarosdy M Wilding G Crawford ED Trump D Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenectomy in men with node-positive prostate cancer N Eng J Med 1999 341 1781 8
36. Iversen P Johansson JE Lodding P et al. Bicalutamide (150mg) versus placebo as immediate therapy alone or as adjuvant to therapy with curative intent for early nonmetastatic prostate cancer: 5.3-year median follow-up from the Scandinavian Prostate Cancer Group Study Number 6 J Urol 2004 172 1871 6
37. Wirth MP See WA McLeod DG Iversen P Morris T Carroll K Casodex Early Prostate Cancer Trialists' Group. Bicalutamide 150mg in addition to standard care in patients with localised or locally advanced prostate cancer: results from the second analysis of the early prostate cancer program at median follow-up of 5.4 years J Urol 2004 172 1865 70
38. Miyake H Sakai I Harada K Hara I Eto H Long-term results of adjuvant hormonal therapy plus radiotherapy following radical prostatectomy for patients with pT3N0 or pT3N1 prostate cancer Int J Urol 2004 11 397 401
39. King CR Presti JC Gill H Brooks J Hancock SL Radiotherapy after radical prostatectomy: does transient androgen suppression improve outcomes? Int J Radiat Oncol Biol Phys 2004 59 341 7