Monoclonal MOG-reactive autoantibody from progressive EAE has the characteristics of a natural antibody

Journal of Neuroimmunology

Volumn 173, Issue 1-2, 2006, Pages 135-145

  Libbey, Jane E ^a   Peterson, Lisa K ^a   Tsunoda, Ikuo ^a   Fujinami, Robert S ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmune diseases; Autoimmunity; B lymphocyte gene rearrangement; Demyelinating diseases; Experimental autoimmune encephalomyelitis; Genetic polymorphism

Indexed keywords

AMINO ACID; B CELL ACTIVATION FACTOR RECEPTOR; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALITIS; AMINO ACID BLOOD LEVEL; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL ACTIVATION; GENE SEQUENCE; GERM LINE; HYBRIDOMA CELL CULTURE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; B-CELL ACTIVATION FACTOR RECEPTOR; BASE SEQUENCE; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENES, IMMUNOGLOBULIN; HYBRIDOMAS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; MEMBRANE PROTEINS; MICE; MICE, CONGENIC; MOLECULAR SEQUENCE DATA; MUTATION; MYELIN-ASSOCIATED GLYCOPROTEIN; POLYMERASE CHAIN REACTION; RECEPTORS, TUMOR NECROSIS FACTOR; SEQUENCE HOMOLOGY;

EID: 33644946283     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.12.010     Document Type: Article

References (49)

1. S.F. Altschul, W. Gish, W. Miller, E.W. Myers, and D.J. Lipman Basic local alignment search tool J. Mol. Biol. 215 1990 403 410
2. L gene expression restored splenic B lymphocyte development in BAFF-R mutant mice J. Immunol. 170 2003 4593 4600
3. S. Amor, N. Groome, C. Linington, M.M. Morris, K. Dornmair, M.V. Gardinier, J.-M. Matthieu, and D. Baker Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice J. Immunol. 153 1994 4349 4356
4. S.M. Antone, E.E. Adderson, N.M.J. Mertens, and M.W. Cunningham Molecular analysis of V gene sequences encoding cytotoxic anti-streptococcal/anti-myosin monoclonal antibody 36.2.2 that recognizes the heart cell surface protein laminin J. Immunol. 159 1997 5422 5430
5. K. Asakura, and M. Rodriguez A unique population of circulating autoantibodies promotes central nervous system remyelination Mult. Scler. 4 1998 217 221
6. R. Baccala, T.V. Quang, M. Gilbert, T. Ternynck, and S. Avrameas Two murine natural polyreactive autoantibodies are encoded by nonmutated germ-line genes Proc. Natl. Acad. Sci. U. S. A. 86 1989 4624 4628
7. L.M. Bagenstose, P. Salgame, and M. Monestier Cytokine regulation of a rodent model of mercuric chloride-induced autoimmunity Environ. Health Perspect. 107 Suppl. 5 1999 807 810
8. L.M. Bagenstose, P. Salgame, and M. Monestier Murine mercury-induced autoimmunity: a model of chemically related autoimmunity in humans Immunol. Res. 20 1999 67 78
9. R. Berland, and H.H. Wortis Origins and functions of B-1 cells with notes on the role of CD5 Annu. Rev. Immunol. 20 2002 253 300
10. P. Bongioanni, C. Fioretti, R. Vanacore, F. Bianchi, F. Lombardo, F. Ambrogi, and G. Meucci Lymphocyte subsets in multiple sclerosis. A study with two-colour fluorescence analysis J. Neurol. Sci. 139 1996 71 77
11. W.L. Carroll, E. Mendel, and S. Levy Hybridoma fusion cell lines contain an aberrant kappa transcript Mol. Immunol. 25 1988 991 995
12. T. Defrance, M. Casamayor-Pallejà, and P.H. Krammer The life and death of a B cell Adv. Cancer Res. 86 2002 195 225
13. J.A. Gross, S.R. Dillon, S. Mudri, J. Johnston, A. Littau, R. Roque, M. Rixon, O. Schou, K.P. Foley, H. Haugen, S. McMillen, K. Waggie, R.W. Schreckhise, K. Shoemaker, T. Vu, M. Moore, A. Grossman, and C.H. Clegg TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS Immunity 15 2001 289 302
14. + B cells: the Ly-1 B lineage? Annu. Rev. Immunol. 6 1988 197 218
15. K.A. Hoag, K. Clise-Dwyer, Y.H. Lim, F.E. Nashold, J. Gestwicki, M.P. Cancro, and C.E. Hayes A quantitative-trait locus controlling peripheral B-cell deficiency maps to mouse Chromosome 15 Immunogenetics 51 2000 924 929
16. H families Eur. J. Immunol. 17 1987 399 403
17. U. Johansson, B. Sander, and P. Hultman Effects of the murine genotype on T cell activation and cytokine production in murine mercury-induced autoimmunity J. Autoimmun. 10 1997 347 355
18. E.A. Kabat, T.T. Wu, H.M. Perry, K.S. Gottesman, and C. Foeller Sequences of Proteins of Immunological Interest 1991 U.S. Government Printing Office Bethesda, MD
19. E. Kirschning, G. Rutter, H. Uhlig, and R. Dernick A sulfatide-reactive human monoclonal antibody obtained from a multiple sclerosis patient selectively binds to the surface of oligodendrocytes J. Neuroimmunol. 56 1995 191 200
20. E. Kirschning, K. Jensen, S. Dübel, G. Rutter, H. Hohenberg, and H. Will Primary structure of the antigen-binding domains of a human oligodendrocyte-reactive IgM monoclonal antibody derived from a patient with multiple sclerosis J. Neuroimmunol. 99 1999 122 130
21. G. Köhler, and C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
22. H segment employed in Ars-A antibodies: implications for the generation of junctional diversity J. Immunol. 137 1986 362 365
23. D.J. Leahy, G.S. Rule, M.M. Whittaker, and H.M. McConnell Sequences of 12 monoclonal anti-dinitrophenyl spin-label antibodies for NMR studies Proc. Natl. Acad. Sci. U. S. A. 85 1988 3661 3665
24. V.M. Lentz, M.P. Cancro, F.E. Nashold, and C.E. Hayes Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse J. Immunol. 157 1996 598 606
25. D.H. Margulies The major histocompatibility complex W.E. Paul Fundamental Immunology Fourth edition 1999 Lippincott-Raven Publishers Philadelphia 263 285
26. P. Matsiota, A. Blancher, B. Doyon, B. Guilbert, M. Clanet, E.D. Kouvelas, and S. Avrameas Comparative study of natural autoantibodies in the serum and cerebrospinal fluid of normal individuals and patients with multiple sclerosis and other neurological diseases Ann. Inst. Pasteur., Immunol. 139 1988 99 108
27. E.E. Max, J.V. Maizel Jr., and P. Leder The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse κ immunoglobulin J and C region genes J. Biol. Chem. 256 1981 5116 5120
28. F. Melchers Actions of BAFF in B cell maturation and its effects on the development of autoimmune disease Ann. Rheum. Dis. 62 Suppl. 2 2003 ii25 ii27
29. E. Mix, T. Olsson, J. Correale, S. Baig, V. Kostulas, O. Olsson, and H. Link B cells expressing CD5 are increased in cerebrospinal fluid of patients with multiple sclerosis Clin. Exp. Immunol. 79 1990 21 27
30. s mice J. Immunol. 152 1994 667 675
31. s) mice: similarities with autoantibodies in spontaneous and heavy metal-induced autoimmunity Eur. J. Immunol. 24 1994 723 730
32. s mice by immunization with nuclear antigens Mol. Immunol. 34 1997 39 51
33. Ozaki, S., 1994. Cell lines and hybridomas. In: Delves, P.J. (Ed.), Cellular Immunology LABFAX, Oxford, UK, Academic Press. BIOS Scientific Publishers Limited, pp. 65-93.
34. A. Perez, J. Lombardero, C. Mateo, G. Mustelier, M. Alfonso, A.M. Vazquez, and R. Perez Immunogenetic analysis of variable regions encoding AB1 and gamma-type AB2 antibodies from the NeuGc-containing ganglioside family Hybridoma 20 2001 211 221
35. 92-106 monoclonal antibodies Keystone Symposia-Central Nervous System Inflammation: Mechanisms, Consequences and Therapeutic Strategies, Snowbird, Utah, January 11-15 2005 105
36. B. Rowley, and M. Monestier Mechanisms of heavy metal-induced autoimmunity Mol. Immunol. 42 2005 833 838
37. H. Sakano, R. Maki, Y. Kurosawa, W. Roeder, and S. Tonegawa Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes Nature 286 1980 676 683
38. κ genes, pseudogenes, relics and orphans in the mouse genome (Appendix to the report by R. Thiebe et al) Eur. J. Immunol. 29 1999 2082 2086
39. B. Schiemann, J.L. Gommerman, K. Vora, T.G. Cachero, S. Shulga-Morskaya, M. Dobles, E. Frew, and M.L. Scott An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway Science 293 2001 2111 2114
40. M. Shulman, C.D. Wilde, and G. Köhler A better cell line for making hybridomas secreting specific antibodies Nature 276 1978 269 270
41. R. Thiebe, K.F. Schäble, A. Bensch, J. Brensing-Küppers, V. Heim, T. Kirschbaum, H. Mitlöhner, M. Ohnrich, S. Pourrajabi, F. Röschenthaler, J. Schwendinger, D. Wichelhaus, I. Zocher, and H.G. Zachau The variable genes and gene families of the mouse immunoglobulin κ locus Eur. J. Immunol. 29 1999 2072 2081
42. J.S. Thompson, S.A. Bixler, F. Qian, K. Vora, M.L. Scott, T.G. Cachero, C. Hession, P. Schneider, I.D. Sizing, C. Mullen, K. Strauch, M. Zafari, C.D. Benjamin, J. Tschopp, J.L. Browning, and C. Ambrose BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF Science 293 2001 2108 2111
43. I.S. Trowbridge, and M.L. Thomas CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development Annu. Rev. Immunol. 12 1994 85 116
44. I. Tsunoda, and R.S. Fujinami Two models for multiple sclerosis: experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis virus J. Neuropathol. Exp. Neurol. 55 1996 673 686
45. I. Tsunoda, and R.S. Fujinami TMEV and neuroantigens: myelin genes and proteins, molecular mimicry, epitope spreading and autoantibody-mediated remyelination E. Lavi C.S. Constantinescu Experimental Models of Multiple Sclerosis 2005 Springer New York 593 616
46. S mouse strains Brain Pathol. 10 2000 402 418
47. L.M. Villar, M.C. Sádaba, E. Roldán, J. Masjuan, P. González-Porqué, N. Villarrubia, M. Espiño, J.A. García-Trujillo, A. Bootello, and J.C. Álvarez-Cermeño Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS J. Clin. Invest. 115 2005 187 194
48. T.J. Waldschmidt, and R.J. Noelle Immunology. Long live the mature B cell - a BAFFling mystery resolved Science 293 2001 2012 2013
49. M. Yan, J.R. Brady, B. Chan, W.P. Lee, B. Hsu, S. Harless, M. Cancro, I.S. Grewal, and V.M. Dixit Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency Curr. Biol. 11 2001 1547 1552