SCOPUS 정보 검색 플랫폼

Tetrahedron Letters

Volumn 47, Issue 15, 2006, Pages 2611-2614

Novel one pot synthesis of polysubstituted pyrazolo[1,5-a]- and imidazo[1,2-a]pyrimidines

(2) Kiselyov, Alexander S a Smith II, Leon a,b

a CHEMDIV INC (United States)

b BRISTOL MYERS SQUIBB (United States)

Author keywords

, Unsaturated imines; Condensations; Imidazo 1,2 a pyrimidines; One pot reactions; Pyrazolo 1,5 a pyrimidines

Indexed keywords

IMIDAZO[1,2 A]PYRIMIDINE DERIVATIVE; PYRAZOLO[1,5 A]PYRIMIDINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMER;

EID: 33644922646 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/j.tetlet.2006.02.031 Document Type: Article

Times cited : (39)

References (27)

1
- 12344258770
- C. Enguehard-Gueiffier, F. Fauvelle, J.-C. Debouzy, A. Peinnequin, I. Thery, V. Dabouis, and A. Gueiffier Eur. J. Pharm. Sci. 24 2005 219
- (2005) Eur. J. Pharm. Sci. , vol.24 , pp. 219
- Enguehard-Gueiffier, C.¹ Fauvelle, F.² Debouzy, J.-C.³ Peinnequin, A.⁴ Thery, I.⁵ Dabouis, V.⁶ Gueiffier, A.⁷

2
- 9644262751
- S. Yamagishi, R. Abe, Y. Inagaki, K. Nakamura, H. Sugawara, D. Inokuma, H. Nakamura, T. Shimizu, M. Takeuchi, A. Yoshimura, R. Bucala, H. Shimizu, and T. Imaizumi Am. J. Pathol. 165 2004 1865
- (2004) Am. J. Pathol. , vol.165 , pp. 1865
- Yamagishi, S.¹ Abe, R.² Inagaki, Y.³ Nakamura, K.⁴ Sugawara, H.⁵ Inokuma, D.⁶ Nakamura, H.⁷ Shimizu, T.⁸ Takeuchi, M.⁹ Yoshimura, A.¹⁰ Bucala, R.¹¹ Shimizu, H.¹² Imaizumi, T.¹³

3
- 19944429835
- G. Trapani, V. Laquintana, N. Denora, A. Trapani, A. Lopedota, A. Latrofa, M. Franco, M. Serra, M.G. Pisu, I. Floris, E. Sanna, G. Biggio, and G. Liso J. Med. Chem. 48 2005 292
- (2005) J. Med. Chem. , vol.48 , pp. 292
- Trapani, G.¹ Laquintana, V.² Denora, N.³ Trapani, A.⁴ Lopedota, A.⁵ Latrofa, A.⁶ Franco, M.⁷ Serra, M.⁸ Pisu, M.G.⁹ Floris, I.¹⁰ Sanna, E.¹¹ Biggio, G.¹² Liso, G.¹³

4
- 20844439370
- A. Geronikaki, E. Babaev, J. Dearden, W. Dehaen, D. Filimonov, I. Galaeva, V. Krajneva, A. Lagunin, F. Macaev, G. Molodavkin, V. Poroikov, S. Pogrebnoi, V. Saloutin, A. Stepanchikova, E. Stingaci, N. Tkach, L. Vlad, and T. Voronina Bioorg. Med. Chem. Lett. 12 2005 6559
- (2005) Bioorg. Med. Chem. Lett. , vol.12 , pp. 6559
- Geronikaki, A.¹ Babaev, E.² Dearden, J.³ Dehaen, W.⁴ Filimonov, D.⁵ Galaeva, I.⁶ Krajneva, V.⁷ Lagunin, A.⁸ MacAev, F.⁹ Molodavkin, G.¹⁰ Poroikov, V.¹¹ Pogrebnoi, S.¹² Saloutin, V.¹³ Stepanchikova, A.¹⁴ Stingaci, E.¹⁵ Tkach, N.¹⁶ Vlad, L.¹⁷ Voronina, T.¹⁸

5
- 33644930169
- PCT Int. Appl. 2004, WO 2004071391.
- Zimmermann, P. J.; Palmer, A.; Brehm, C.; Klein, T.; Senn-Bilfinger, J.; Simon, W.-A.; Postius, S.; Chiesa, M. V.; Buhr, W.; Kromer, W. PCT Int. Appl. 2004, WO 2004071391.
- Zimmermann, P.J.¹ Palmer, A.² Brehm, C.³ Klein, T.⁴ Senn-Bilfinger, J.⁵ Simon, W.-A.⁶ Postius, S.⁷ Chiesa, M.V.⁸ Buhr, W.⁹ Kromer, W.¹⁰

6
- 33644896412
- PCT Int. Appl. 2004, WO 2004101566.
- Mueller, B.; Zimmermann, P.; Scheufler, C.; Kohl, B. PCT Int. Appl. 2004, WO 2004101566.
- Mueller, B.¹ Zimmermann, P.² Scheufler, C.³ Kohl, B.⁴

7
- 33644919290
- PCT Int. Appl. 2005, WO 2005041961.
- Fernstroem, P.; Hasselgren, G. PCT Int. Appl. 2005, WO 2005041961.
- Fernstroem, P.¹ Hasselgren, G.²

8
- 0030931518
- A. Olivier, M. Sevrin, F. Durant, and P. George Bioorg. Med. Chem. Lett. 7 1997 2277
- (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 2277
- Olivier, A.¹ Sevrin, M.² Durant, F.³ George, P.⁴

9
- 0028901230
- D.J. Sanger Behav. Pharm. 6 1995 116
- (1995) Behav. Pharm. , vol.6 , pp. 116
- Sanger, D.J.¹

10
- 12944331138
- T.S. Harrison, and G.M. Keating CNS Drugs 19 2005 65
- (2005) CNS Drugs , vol.19 , pp. 65
- Harrison, T.S.¹ Keating, G.M.²

11
- 25444529945
- S. Miwa, A. Mizokami, E.T. Keller, R. Taichman, J. Zhang, and M. Namiki Cancer Res. 65 2005 8818
- (2005) Cancer Res. , vol.65 , pp. 8818
- Miwa, S.¹ Mizokami, A.² Keller, E.T.³ Taichman, R.⁴ Zhang, J.⁵ Namiki, M.⁶

12
- 20244367149
- N. Cui, T. Nomura, H. Noma, K. Yokoo, R. Takagi, S. Hashimoto, M. Okamoto, M. Sato, G. Yu, C. Guo, and T. Shibahala Clin. Cancer Res. 11 2005 2713
- (2005) Clin. Cancer Res. , vol.11 , pp. 2713
- Cui, N.¹ Nomura, T.² Noma, H.³ Yokoo, K.⁴ Takagi, R.⁵ Hashimoto, S.⁶ Okamoto, M.⁷ Sato, M.⁸ Yu, G.⁹ Guo, C.¹⁰ Shibahala, T.¹¹

13
- 18244410156
- Y. Ling, G. Sahota, S. Odeh, J.M.W. Chan, F.G. Araujo, S.N.J. Moreno, and E. Oldfield J. Med. Chem. 48 2005 3130
- (2005) J. Med. Chem. , vol.48 , pp. 3130
- Ling, Y.¹ Sahota, G.² Odeh, S.³ Chan, J.M.W.⁴ Araujo, F.G.⁵ Moreno, S.N.J.⁶ Oldfield, E.⁷

14
- 12244295754
- T. Yuasa, M. Nogawa, S. Kimura, A. Yokota, K. Sato, H. Segawa, J. Kuroda, and T. Maekawa Clin. Cancer Res. 11 2005 853
- (2005) Clin. Cancer Res. , vol.11 , pp. 853
- Yuasa, T.¹ Nogawa, M.² Kimura, S.³ Yokota, A.⁴ Sato, K.⁵ Segawa, H.⁶ Kuroda, J.⁷ Maekawa, T.⁸

15
- 20144366009
- C. Hamdouchi, B. Zhong, J. Mendoza, E. Collins, C. Jaramillo, J.E. De Diego, D. Robertson, C.D. Spencer, B.D. Anderson, S.A. Watkins, F. Zhang, and H.B. Brooks Bioorg. Med. Chem. Lett. 15 2005 1943
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 1943
- Hamdouchi, C.¹ Zhong, B.² Mendoza, J.³ Collins, E.⁴ Jaramillo, C.⁵ De Diego, J.E.⁶ Robertson, D.⁷ Spencer, C.D.⁸ Anderson, B.D.⁹ Watkins, S.A.¹⁰ Zhang, F.¹¹ Brooks, H.B.¹²

16
- 19544369667
- G. Xia, J. Li, A. Peng, S. Lai, S. Zhang, J. Shen, Z. Liu, X. Chen, and R. Ji Bioorg. Med. Chem. Lett. 15 2005 2790
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 2790
- Xia, G.¹ Li, J.² Peng, A.³ Lai, S.⁴ Zhang, S.⁵ Shen, J.⁶ Liu, Z.⁷ Chen, X.⁸ Ji, R.⁹

17
- 20144388228
- D. Kim, L. Wang, J.J. Hale, C.L. Lynch, R.J. Budhu, M. MacCoss, S.G. Mills, L. Malkowitz, Sandra L. Gould, J.A. DeMartino, M.S. Springer, D. Hazuda, M. Miller, J. Kessler, R.C. Hrin, G. Carver, A. Carella, K. Henry, J. Lineberger, W.A. Schleif, and E.A. Emini Boorg. Med. Chem. Lett. 15 2005 2129
- (2005) Boorg. Med. Chem. Lett. , vol.15 , pp. 2129
- Kim, D.¹ Wang, L.² Hale, J.J.³ Lynch, C.L.⁴ Budhu, R.J.⁵ MacCoss, M.⁶ Mills, S.G.⁷ Malkowitz, L.⁸ Gould Sandra, L.⁹ Demartino, J.A.¹⁰ Springer, M.S.¹¹ Hazuda, D.¹² Miller, M.¹³ Kessler, J.¹⁴ Hrin, R.C.¹⁵ Carver, G.¹⁶ Carella, A.¹⁷ Henry, K.¹⁸ Lineberger, J.¹⁹ Schleif, W.A.²⁰ Emini, E.A.²¹ more..

18
- 19544368936
- A.S. Kiselyov Tetrahedron Lett. 46 2005 4487
- (2005) Tetrahedron Lett. , vol.46 , pp. 4487
- Kiselyov, A.S.¹

19
- 22844434168
- J. Gerencser, G. Panka, T. Nagy, O. Egyed, G. Dorman, L. Uerge, and F. Darvas J. Comb. Chem. 7 2005 530
- (2005) J. Comb. Chem. , vol.7 , pp. 530
- Gerencser, J.¹ Panka, G.² Nagy, T.³ Egyed, O.⁴ Dorman, G.⁵ Uerge, L.⁶ Darvas, F.⁷

20
- 33644893498
- H.-Y. Huang, R.-S. Hou, H.-M. Wang, and L.-C. Chen J. Chin. Chem. Soc. 51 2004 1377
- (2004) J. Chin. Chem. Soc. , vol.51 , pp. 1377
- Huang, H.-Y.¹ Hou, R.-S.² Wang, H.-M.³ Chen, L.-C.⁴

21
- 0028803454
- A.S. Kiselyov Tetrahedron Lett. 36 1995 9297
- (1995) Tetrahedron Lett. , vol.36 , pp. 9297
- Kiselyov, A.S.¹

22
- 13744252141
- A.S. Kiselyov Tetrahedron Lett. 46 2005 1663
- (2005) Tetrahedron Lett. , vol.46 , pp. 1663
- Kiselyov, A.S.¹

23
- 0028814403
- W.S.S. Shin, K. Lee, and D.Y. Oh Tetrahedron Lett. 36 1995 281
- (1995) Tetrahedron Lett. , vol.36 , pp. 281
- Shin, W.S.S.¹ Lee, K.² Oh, D.Y.³

24
- 0000130813
- F. Palacios, J. Garcia, A.M. Ochoa de Retana, and J. Oyarzabal Heterocycles 41 1995 1915 and references cited therein
- (1995) Heterocycles , vol.41 , pp. 1915
- Palacios, F.¹ Garcia, J.² Ochoa De Retana, A.M.³ Oyarzabal, J.⁴

25
- 0026035165
- K. Lee, and D.Y. Oh Synthesis 1991 213
- (1991) Synthesis , pp. 213
- Lee, K.¹ Oh, D.Y.²

26
- 33644898270
- note
- 4, concentrated to ca. 10 mL, cooled down in the freezer, and triturated with cold ether. The resulting crystals were collected, washed with ether, recrystallized from EtOH, and dried in vacuo to yield analytically pure imidazo[1,2-a]pyridines. Observed significant NOE's for the products 4i and 4j :

27
- 33644895581
- note
- 4: C, 70.39; H, 3.38; N, 15.63. Found: C, 70.13; H, 3.19; N, 15.45.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.