2,3-Diarylimidazo[1,2-a]pyridines as potential inhibitors of UV-induced keratinocytes apoptosis: Synthesis, pharmacological properties and interactions with model membranes and oligonucleotides by NMR

European Journal of Pharmaceutical Sciences

Volumn 24, Issue 2-3, 2005, Pages 219-227

  Enguehard Gueiffier, Cécile ^a   Fauvelle, Florence ^b   Debouzy, Jean Claude ^b   Peinnequin, André ^b   Thery, Isabelle ^a   Dabouis, Vincent ^b   Gueiffier, Alain ^a  

^a UNIVERSITÉ DE TOURS   (France)

^b CENTRE DE RECHERCHES   (France)

Author keywords

Apoptosis; Imidazo 1,2 a pyridine; Model membrane; NMR; Oligonucleotide

Indexed keywords

2 (3,4 DIFLUOROPHENYL) 3 IODOIMIDAZO[1,2 A]PYRIDINE; 2 (3,4 DIFLUOROPHENYL) 3 PHENYLIMIDAZO[1,2 A]PYRIDINE; 2 (3,4 DIFLUOROPHENYL)IMIDAZO[1,2 A]PYRIDINE; 2 (4 FLUOROPHENYL)IMIDAZO[1,2 A]PYRIDINE; 2 (4 TRIFLUOROMETHYLPHENYL)IMIDAZO[1,2 A]PYRIDINE; 3 IODO 2 (4 TRIFLUOROMETHYLPHENYL)IMIDAZO[1,2 A]PYRIDINE; 3 PHENYL 2 (4 TRIFLUOROMETHYLPHENYL)IMIDAZO[1,2 A]PYRIDINE; OLIGONUCLEOTIDE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANISOTROPY; APOPTOSIS; ARTICLE; CELL MEMBRANE FLUIDITY; CELL PROTECTION; CONTROLLED STUDY; CYCLIZATION; DEUTERON NUCLEAR MAGNETIC RESONANCE; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GC RICH SEQUENCE; HUMAN; HUMAN CELL; IODINATION; KERATINOCYTE; LIPID BILAYER; MOLTING; NUCLEAR MAGNETIC RESONANCE; PHASE TRANSITION; PHOSPHOLIPID MEMBRANE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RADIATION INJURY; SUZUKI REACTION; TEMPERATURE DEPENDENCE;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DEOXYRIBONUCLEOTIDES; HUMANS; IMIDAZOLES; KERATINOCYTES; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANES, ARTIFICIAL; PYRIDINES; ULTRAVIOLET RAYS;

EID: 12344258770     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2004.10.009     Document Type: Article

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