Kinetics of 14C distribution after tracer dose of 14C-lutein in an adult woman

Lipids

Volumn 40, Issue 10, 2005, Pages 1069-1073

  De Moura, Fabiana F ^a   Ho, Charlene C ^a   Getachew, Girma ^a   Hickenbottom, Sabrina ^a   Clifford, Andrew J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEALTH RISKS; HYDROCARBONS; MASS SPECTROMETRY; METABOLISM; PIGMENTS; PLANTS (BOTANY);

CAROTENE; CAROTENOID; HUMAN LUTEIN METABOLISM; LUTEIN;

LIPIDS;

BETA CAROTENE; CARBON 14; CAROTENOID; CHYLOMICRON; OLIVE OIL; TRACER; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; XANTHOPHYLL; XANTHOPHYLL C 14; CARBON; DIAGNOSTIC AGENT;

ARTICLE; BANANA; BLOOD ANALYSIS; DIET SUPPLEMENTATION; DIETARY INTAKE; FECES ANALYSIS; FEMALE; HALF LIFE TIME; HUMAN; HUMAN EXPERIMENT; MALE; MASS SPECTROMETRY; NORMAL HUMAN; RETINA MACULA AGE RELATED DEGENERATION; RISK BENEFIT ANALYSIS; SPINACH; URINALYSIS; VEGETABLE; XANTHOPHYLL CYCLE; AREA UNDER THE CURVE; BIOAVAILABILITY; BLOOD; CHEMISTRY; FECES; MIDDLE AGED; ORAL DRUG ADMINISTRATION; URINE;

SPINACIA OLERACEA;

ADMINISTRATION, ORAL; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CARBON RADIOISOTOPES; FECES; FEMALE; HUMANS; LUTEIN; MIDDLE AGED;

EID: 33644875399     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-005-1471-4     Document Type: Article

References (35)

1. Sommerburg, O., Keunen, J.E., Bird, A.C., and van Kuijk, F.J. (1998) Fruits and Vegetables That Are Sources for Lutein and Zeaxanthin: The Macular Pigment in Human Eyes, Br. J. Ophthalmol. 82, 907-910.
2. Eye Disease Case-Control Study Group (1993) Antioxidant Status and Neovascular Age-Related Macular Degeneration, Arch. Ophthalmol. 111, 104-109.
3. Seddon, J.M., Ajani, U.A., Sperduto, R.D., Hiller, R., Blair, N., Burton, T.C., Farber, M.D., Gragoudas, E.S., Haller, J., Miller, D.T., et al. (1994) Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration. Eye Disease Case-Control Study Group, JAMA 272, 1413-1420.
4. Schalch, W., Dayhaw-Barker, P., and Barker, F. (1999) The Carotenoids of the Human Retina, CRC Press, Boca Raton, Florida.
5. Schalch, W. (1992) Carotenoids in the Retina-A Review of Their Possible Role in Preventing or Limiting Damage Caused by Light and Oxygen, in Free Radicals and Aging (Emerit, I., and Chance, B., eds.), pp. 280-298, Birkhauser Verlag, Basel, Switzerland.
6. Snodderly, D.M. (1995) Evidence for Protection Against Age-Related Macular Degeneration by Carotenoids and Antioxidant Vitamins, Am. J. Clin. Nutr. 62, 1448S-1461S.
7. Rapp, L.M., Maple, S.S., and Choi, J.H. (2000) Lutein and Zeaxanthin Concentrations in Rod Outer Segment Membranes from Perifoveal and Peripheral Human Retina, Invest. Ophthalmol. Vis. Sci. 41, 1200-1209.
8. Khachik, F., Beecher, G.R., and Smith, J.C., Jr. (1995) Lutein, Lycopene, and Their Oxidative Metabolites in Chemoprevention of Cancer, J. Cell. Biochem. Suppl. 22, 236-246.
9. Landrum, J.T., Bone, R.A., Joa, H., Kilburn, M.D., Moore, L.L., and Sprague, K.E. (1997) A One Year Study of the Macular Pigment: The Effect of 140 Days of a Lutein Supplement, Exp. Eye Res. 65, 57-62.
10. Bone, R.A., Landrum, J.T., Guerra, L.H., and Ruiz, C.A. (2003) Lutein and Zeaxanthin Dietary Supplements Raise Macular Pigment Density and Serum Concentrations of These Carotenoids in Humans, J. Nutr. 133, 992-998.
11. 4 Plant Sources, J. Chromatogr. A. 800, 51-58.
12. 13C Tracer to Quantify the Plasma Appearance of a Physiological Dose of Lutein in Humans, Lipids 35, 339-348.
13. 13C- Labeled and Endogenous β-Carotene, Lutein, and Vitamin A in Human Plasma, Lipids 36, 1277-1282.
14. Lienau, A., Glaser, T., Tang, G., Dolnikowski, G.G., Grusak, M. A., and Albert, K. (2003) Bioavailability of Lutein in Humans from Intrinsically Labeled Vegetables Determined by LC-APCI-MS, J. Nutr. Biochem. 14, 663-670.
15. Dueker, S.R., Jones, A.D., and Clifford, A.J. (1998) Protocol Development for Biological Tracer Studies, Adv. Exp. Med. Biol. 445, 363-378.
16. Dueker, S.R., Lin, Y., Buchholz, B.A., Schneider, P.D., Lame, M.W., Segall, H.J., Vogel, J.S., and Clifford, A.J. (2000) Long-term Kinetic Study of β-Carotene, Using Accelerator Mass Spectrometry in an Adult Volunteer, J. Lipid Res. 41, 1790-1800.
17. Burri, B.J., and Clifford, A.J. (2004) Carotenoid and Retinoid Metabolism: Insights from Isotope Studies, Arch. Biochem. Biophys. 430, 110-119.
18. Le Vuong, T., Buchholz, B.A., Lame, M.W., and Dueker, S.R. (2004) Phytochemical Research Using Accelerator Mass Spectrometry, Nutr. Rev. 62, 375-388.
19. Leenheer, A., Lambert, W., and Neils, H. (1992) Modern Chromatographic Analysis of Vitamins, 2nd edn., Marcel Dekker, New York.
20. Pella, E. (1990) Elemental Organic Analysis, Am. Lab. 22, 116-125.
21. Castenmiller, J.J., West, C.E., Linssen, J.P., van het Hof, K.H., and Voragen, A.G. (1999) The Food Matrix of Spinach Is a Limiting Factor in Determining the Bioavailability of β-Carotene and to a Lesser Extent of Lutein in Humans. J. Nutr. 129, 349-355.
22. Chung, H.Y., Rasmussen, H.M., and Johnson, E.J. (2004) Lutein Bioavailability Is Higher from Lutein-Enriched Eggs Than from Supplements and Spinach in Men, J. Nutr. 134, 1887-1893.
23. van het Hof, K.H., Brouwer, I.A., West, C.E., Haddeman, E., Steegers-Theunissen, R.P., van Dusseldorp, M., Weststrate, J.A., Eskes, T.K., and Hautvast, J.G. (1999) Bioavailability of Lutein from Vegetables Is 5 Times Higher Than That of β-Carotene. Am. J. Clin. Nutr. 70, 261-268.
24. Chitchumroonchokchai, C., Schwartz, S.J., and Pailla, M.L. (2004) Assessment of Lutein Bioavailability from Meals and a Supplement Using Simulated Digestion and Caco-2 Human Intestinal Cells, J. Nutr. 134, 2280-2286.
25. Borel, P., Grolier, P., Armand, M., Partier, A., Lafont, H., Lairon, D., and Azais-Braesco, V. (1996) Carotenoids in Biological Emulsions: Solubility, Surface-to-Core Distribution, and Release from Lipid Droplets, J. Lipid Res. 37, 250-261.
26. Kostic, D., White, W.S., and Olson, J.A. (1995) Intestinal Absorption, Serum Clearance, and Interactions Between Lutein and β-Carotene When Administered to Human Adults in Separate or Combined Oral Doses, Am. J. Clin. Nutr. 62, 604-610.
27. Kurilich, A.C., Britz, S.J., Clevidence, B.A., and Novotny, J.A. (2003) Isotopic Labeling and LC-APCI-MS Quantification for Investigating Absorption of Carotenoids and Phylloquinone from Kale (Brassica oleracea), J. Agric. Food Chem. 51, 4877-4883.
28. Novotny, J.A., Kurilich, A.C., Britz, S.J., And Clevidence, B.A. (2005) Plasma Appearance of Labeled β-Carotene, Lutein, and Retinol in Humans After Consumption of Isotopically Labeled Kale, J. Lipid Res. 46, 1896-1903.
29. Lemke, S.L., Dueker, S.R., Follett, J.R., Lin, Y., Carkeet, C., Buchholz, B.A., Vogel, J.S., and Clifford, A.J. (2003) Absorption and Retinol Equivalence of β-Carotene in Humans Is Influenced by Dietary Vitamin A Intake, J. Lipid Res. 44, 1591-1600.
30. Clevidence, B.A., and Bieri, J. (1993) Association of Carotenoids with Human Plasma Lipoproteins, Methods Enzymol. 214, 33-46.
31. Reboul, E., Abou, L., Mikail, C., Ghiringhelli, O., Andre, M., Portugal, H., Jourdheuil-Rahmani, D., Amiot, M.J., Lairon, D., and Borel, P. (2005) Lutein Transport by Caco-2 TC-7 Cells Occurs Partly by a Facilitated Process Involving the Scavenger Receptor Class B Type I (SR-BI), Biochem. J. 387, 455-461.
32. Thurmann, P.A., Schalch, W., Aebischer, J.C., Tenter, U., and Cohn, W. (2005) Plasma Kinetics of Lutein, Zeaxanthin, and 3-Dehydro-lutein After Multiple Oral Doses of a Lutein Supplement, Am. J. Clin. Nutr. 82, 88-97.
33. Hartmann, D., Thurmann, P.A., Spitzer, V., Schalch, W., Manner, B., and Cohn, W. (2004) Plasma Kinetics of Zeaxanthin and 3′-Dehydro-lutein After Multiple Oral Doses of Synthetic Zeaxanthin, Am. J. Clin. Nutr. 79, 410-417.
34. Burri, B.J., Neidlinger, T.R., and Clifford, A.J. (2001) Serum Carotenoid Depletion Follows First-Order Kinetics in Healthy Adult Women Fed Naturally Low Carotenoid Diets, J. Nutr. 131, 2096-2100.
35. Rock, C.L., Swendseid, M.E., Jacob, R.A., and McKee, R.W. (1992) Plasma Carotenoid Levels in Human Subjects Fed a Low Carotenoid Diet, J. Nutr. 122, 96-100.