Functional mapping of disease susceptibility loci using cell biology

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 10, 2006, Pages 3698-3703

  Antinozzi, Peter A ^a   Garcia Diaz, Alejandro ^a   Hu, Chuan ^a   Rothman, James E ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

Diabetes; Functional genomics; Insulin; Laminin; RNA interference

Indexed keywords

LAMININ; LAMININ ALPHA1; LAMININ RECEPTOR; LAMININ RECEPTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; BIOLOGY; CELL BASED SECRETION ASSAY; CELL FUNCTION; CELL LINE; CHROMOSOME 18P; CONTROLLED STUDY; DISEASE PREDISPOSITION; FUNCTIONAL GENOMICS; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE LOCUS; GENE MAPPING; HIGH THROUGHPUT SCREENING; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; STATISTICAL ANALYSIS;

CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 18; DIABETES MELLITUS; GENETIC DISEASES, INBORN; HUMANS; ISLETS OF LANGERHANS; LAMININ; RECEPTORS, LAMININ; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

ANIMALIA;

EID: 33644870149     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510521103     Document Type: Article

References (47)

1. Hanis, C. L., Boerwinkle, E., Chakraborty, R., Ellsworth, D. L., Concannon, P., Stirling, B., Morrison, V. A., Wapelhorst, B., Spielman, R. S., Gogolin-Ewens, et al. (1996) Nat. Genet. 13, 161-166.
2. Almind, K., Doria, A. & Kahn, C. R. (2001) Nat. Med. 7, 277-279.
3. Florez, J. C., Hirschhorn, J. & Altshuler, D. (2003) Annu. Rev. Genomics Hum. Genet. 4, 257-291.
4. Phillips, T. J. & Belknap, J. K. (2002) Nat. Rev. Neurosci. 3, 478-485.
5. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K. & Tuschl, T. (2001) Nature 411, 494-498.
6. DasGupta, R., Kaykas, A., Moon, R. T. & Perrimon, N. (2005) Science 308, 826-833.
7. Kim, J. K., Gabel, H. W., Kamath, R. S., Tewari, M., Pasquinelli, A., Ruai, J.-F., Kennedy, S., Dybbs, M., Bertin, N., Kaplan, J. M., et al. (2005) Science 308, 1164-1167.
8. Kaykas, A. & Moon, R. T. (2004) BMC Cell Biol. 5, 16.
9. Zheng, L., Liu, J., Batalov, S., Zhou, D., Orth, A., Ding, S. & Schultz, P. G. (2004) Proc. Natl. Acad. Sci. USA 101, 135-140.
10. Parker, A., Meyer, J., Lewitzky, S., Rennich, J. S., Chan, G., Thomas, J. D., Orho-Melander, M, Lehtovirta, M., Forsblom, C., Hyrkkö, A., et al. (2001) Diabetes 50, 675-680.
11. van Tilburg, J. H. O., Sandkuijl, L. A., Strengman, E., van Someren, H., Rigters-Aris, C. A. E., Pearson, P. L., van Haeften, T. W. & Wijmenga, C. (2003) J. Clin. Endocrinol Metab 88, 2223-2230.
12. Aulchenko, Y. S., Vaessen, N., Heutink, P., Pullen, J., Snijders, P. J. L. M., Hofman, A., Sandkuijl, L. A., Houwing-Duistermaat, J. J., Edwards, M., Bennett, S., et al. (2003) Diabetes 52, 3001-3004.
13. Elbein, S. C., Hoffman, M. D., Teng, K., Leppert, M. F. & Hasstedt, S. J. (1999) Diabetes 48, 1175-1182.
14. Yeh, R. F., Lim, L. P. & Burge, C. B. (2001) Genome Res. 11, 803-816.
15. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410.
16. Reynolds, A., Leake, D., Boese, Q., Scaringe, S., Marshall, W. S. & Khvorova, A. (2004) Nat. Biotechnol. 22, 326-330.
17. Jagla, B., Aulner, N., Kelly, P. D., Song, D., Volchuk, A., Zatorski, A., Shum, D., Mayer, T., Angelis, D. A. D., Ouerfelli, O., et al. (2005) RNA 11, 864-872.
18. Huppi, K., Martin, S. E. & Caplen, N. J. (2005) Mol. Cell 17, 1-10.
19. Anonymous (2003) Nat. Cell Biol. 5, 489-490.
20. Merglen, A., Theander, S., Rubi, B., Chaffard, G., Wollheim, C. B. & Maechler, P. (2004) Endocrinology 145, 667-678.
21. Wick, P. F., Senter, R. A., Parsels, L. A., Uhler, M. D. & Holz, R. W. (1993) J. Biol. Chem. 268, 10983-10989.
22. Maechler, P., Antinozzi, P. A. & Wollheim, C. B. (2000) IUBMB Life 50, 27-31.
23. Iezzi, M., Kouri, G., Fukuda, M. & Wollheim, C. B. (2004) J. Cell Sci. 117, 3119-3127.
24. Antinozzi, P. A., Ishihara, H., Newgard, C. B. & Wollheim, C. B. (2002) J. Biol. Chem. 277, 11746-11755.
25. Yamagata, K., Oda, N., Kaisaki, P. J., Menzel, S., Furuta, H., Vaxillaire, M., Southam, L., Cox, R. D., Lathrop, G. M., Boriraj, V. V., et al. (1996) Nature 384, 455-458.
26. Rich, S. S., Bowden, D. W., Haffner, S. M., Norris, J. M., Saad, M. F., Mitchell, B. D., Rotter, J. I., Langefeld, C. D., Wagenknecht, L. E. & Bergman, R. N. (2004) Diabetes 53, 1866-1875.
27. Miner, J. H. & Yurchenco, P. D. (2004) Annu. Rev. Cell Dev. Biol. 20, 255-284.
28. Wewer, U. M., Liotta, L. A., Jaye, M., Ricca, G. A., Drohan, W. N., Claysmith, A. P., Rao, C. N., Wirth, P., Coligan, J. E. & Albrechtsen, R. (1986) Proc. Natl. Acad. Sci. USA 83, 7137-7141.
29. Castronovo, V., Taraboletti, G. & Sobel, M. E. (1991) J. Biol. Chem. 266, 20440-20446.
30. Kazmin, D. A., Chinenov, Y., Larson, E. & Starkey, J. R. (2003) Biochem. Biophys. Res. Commun. 300, 161-166.
31. Goodge, K. A. & Hutton, J. C. (2000) Semin. Cell Dev. Biol. 11, 235-242.
32. Knight, S. W. & Docherty, K. (1992) J. Mol. Endocrinol. 8, 225-234.
33. Jiang, F.-X. & Harrison, L. C. (2005) Differentiation 73, 45-49.
34. Vasir, B., Aiello, L. P., Yoon, K. H., Quickel, R. R., Bonner-Weir, S. & Weir, G. C. (1998) Diabetes 47, 1894-1903.
35. Bonner-Weir, S., Taneja, M., Weir, G. C., Tatarkiewicz, K., Song, K. H., Sharma, A. & O'Neil, J. J. (2000) Proc. Natl. Acad. Sci. USA 97, 7999-8004.
36. Gao, R., Ustinov, J., Pulkkinen, M.-A., Lundin, K., Korsgren, O. & Otonkoski, T. (2003) Diabetes 52, 2007-2015.
37. Jiang, F. X., Cram, D. S., DeAizpurua, H. J. & Harrison, L. C. (1999) Diabetes 48, 722-730.
38. Hu, C., Oliver, J. A., Goldberg, M. R. & Al-Awqati, Q. (2001) Am J. Physiol. Renal Physiol. 281, F739-F750.
39. Lifson, N., Lassa, C. V. & Dixit, P. K. (1985) Am J. Physiol. 249, E43-E48.
40. Geutskens, S. B., Homo-Delarche, F., Pleau, J.-M. Durant, S., Drexhage, H. A. & Savino, W. (2004) Cell Tissue Res. 318, 579-589.
41. Wiedmann, M., Huth, A. & Rapoport, T. A. (1986) FEBS Lett. 194, 139-145.
42. Kalies, K. U., Görlich, D. & Rapoport, T. A. (1994) J. Cell Biol. 126, 925-934.
43. Aitman, T. J., Glazier, A. M., Wallace, C. A., Cooper, L. D., Norsworthy, P. J., Wahid, F. N., Al-Majali, K. M., Trembling, P. M., Mann, C. J., Shoulders, C. C., et al. (1999) Nat. Genet. 21, 76-83.
44. Singer, J. B., Hill, A. E., Burrage, L. C., Olszens, K. R., Song, J., Justice, M., O'Brien, W. E., Conti, D. V., Witte, J. S., Lander, E. S., et al. (2004) Science 304, 445-448.
45. Asfari, M., Janjic, D., Meda, P., Li, G., Halban, P. A. & Wollheim, C. B. (1992) Endocrinology 130, 167-178.
46. Rasband, W. S. (1997-2006) IMAGE J (National Institutes of Health, Bethesda).
47. Palmer, N. D., Langefeld, C. D., Campbell, J. K., Williams, A. H., Saad, M. F., Norris, J. M., Haffner, S. M., Rotter, J. I., Wagenknecht, L. E., Bergman, R. N., et al. (2006) Diabetes, in press.