Cyclooxygenase-2 induction after oral surgery does not entirely account for analgesia after selective blockade of cyclooxygenase 2 in the preotoerative period

Anesthesiology

Volumn 104, Issue 1, 2006, Pages 152-157

  Fornai, Matteo ^a   Colucci, Rocchina ^a   Graziani, Filippo ^b   Cei, Silvia ^b   Antonioli, Luca ^a   Tonelli, Matteo ^b   Vassalle, Cristina ^c   Blandizzi, Corrado ^a   Gabriele, Mario ^b   Tacca, Mario Del ^a,b  

^a Division of Pharmacology and Chemotherapy   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ISOENZYME; MESSENGER RNA; NAPROXEN; PLACEBO; PROSTAGLANDIN E2; ROFECOXIB; SYNFLEX FORTE; UNCLASSIFIED DRUG; ACTIN; LACTONE; PROSTAGLANDIN; SULFONE;

ADULT; ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOLOSTOP; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SELECTIVITY; ENZYME INDUCTION; FEMALE; GINGIVA; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLAR TOOTH; ORAL SURGERY; PAIN ASSESSMENT; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RANDOMIZED CONTROLLED TRIAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; TOOTH EXTRACTION; VISUAL ANALOG SCALE; BIOSYNTHESIS; ENZYMOLOGY; METABOLISM; MICRODIALYSIS;

ACTINS; ADULT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LACTONES; MALE; MICRODIALYSIS; NAPROXEN; ORAL SURGICAL PROCEDURES; PAIN, POSTOPERATIVE; PROSTAGLANDINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFONES;

EID: 33644868450     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/00000542-200601000-00021     Document Type: Article

References (27)

1. Barden J, Edwards JE, McQuay HJ, Wiffen PJ, Moore RA: Relative efficacy of oral analgesics after third molar extraction. Br Dent J 2004; 197:407-11
2. Dionne RA, Khan AA, Gordon SM: Analgesia and COX-2 inhibition. Clin Exp Rheumatol 2001; 19 (suppl 25):S63-70
3. Stephens JM, Pashos CL, Haider S, Wong JM: Making progress in the management of postoperative pain: A review of the cyclooxygenase 2-specific inhibitors. Pharmacotherapy 2004; 24:1714-31
4. Hawkey CJ: COX-2 inhibitors. Lancet 1999; 353:307-14
5. Warner TD, Mitchell JA: Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic. FASEB J 2004; 18:790-804
6. Cicconetti A, Bartoli A, Ripari F, Ripari A: COX-2 selective inhibitors: A literature review of analgesic efficacy and safety in oral-maxillofacial surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 97:139-46
7. Desjardins PJ, Shu VS, Recker DP, Verburg KM, Woolf CJ: A single preoperative oral dose of valdecoxib, a new cyclooxygenase-2 specific inhibitor, relieves post-oral surgery or bunionectomy pain. ANESTHESIOLOGY 2002; 97:565-73
8. Khan AA, Brahim JS, Rowan JS, Dionne RA: In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model. Clin Pharmacol Ther 2002; 72:44-9
9. Savage MG, Henry MA: Preoperative nonsteroidal anti-inflammatory agents: Review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98:146-52
10. Buvanendran A, Kroin JS, Tuman KJ, Lubenow TR, Elmofty D, Moric M, Rosenberg AG: Effects of perioperative administration of a selective cyclooxygenase-2 inhibitor on pain management and recovery of function after knee replacement: A randomized controlled trial. JAMA 2003; 290:2411-8
11. Ma H, Tang J, White PF, Zaentz A, Wender RH, Sloninsky A, Naruse R, Kariger R, Quon R, Wood D, Carroll BJ: Perioperative rofecoxib improves early recovery after outpatient herniorrhaphy. Anesth Analg 2004; 98:970-5
12. Sinatra RS, Shen QJ, Halaszynsky T, Luter MA, Shaheen Y: Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: The effects on effort-dependent pain and pulmonary function. Anesth Analg 2004; 98:135-40
13. Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR: Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis. Proc Natl Acad Sci U S A 1999; 96:7563-8
14. Issioui T, Klein KW, White PF, Watcha MF, Skrivanek GD, Jones SB, Hu J, Marple BF, Ing C: Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgery. ANESTHESIOLOGY 2002; 97:931-7
15. Hla T, Neilson K: Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci U S A 1992; 89:7384-8
16. 2 production. Br J Pharmacol 2005; 144:338-48
17. Bekker A, Cooper PR, Frempong-Boadu A, Babu R, Errico T, Lebovits A: Evaluation of preoperative administration of the cyclooxygenase-2 inhibitor rofecoxib for the treatment of postoperative pain after lumbar disc surgery. Neurosurgery 2002; 50:1053-8
18. Gordon SM, Brahim JS, Rowan J, Kent A, Dionne RA: Peripheral prostanoid levels and nonsteroidal anti-inflammatory drug analgesia: Replicate clinical trials in a tissue injury model. Clin Pharmacol Ther 2002; 72:175-83
19. Sinatra R: Role of COX-2 inhibitors in the evolution of acute pain management. J Pain Symptom Manage. 2002; 24 (suppl 1):S18-27
20. Samad TA, Sapirstein A, Woolf CJ: Prostanoids and pain: Unraveling mechanisms and revealing therapeutic targets. Trends Mol Med 2002; 8:390-6
21. Yaksh TL, Dirig DM, Conway CM, Svensson C, Luo ZD, Isakson PC: The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1. J Neurosci 2001; 21:5847-53
22. Zhu X, Conklin ED, Eisenach JC: Cyclooxygenase-1 in the spinal cord plays an important role in postoperative pain. Pain 2003; 104:15-23
23. Zhu X, Conklin ED, Eisenach JC: Preoperative inhibition of cyclooxygenase-1 in the spinal cord reduces postoperative pain. Anesth Analg 2005; 100:1390-3
24. Svensson CI, Yaksh TL: The spinal phospholipase-cyclooxygenase-prostanoid cascade in nociceptive processing. Annu Rev Pharmacol Toxicol 2002; 42:553-83
25. Ghilardi JR, Svensson CI, Rogers SD, Yaksh TL, Mantyh PW: Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia. J Neurosci 2004; 24:2727-32
26. 2-mediated inflammatory pain sensitization. Science 2004; 304:884-7
27. Dembo G, Park SB, Kharasch ED: Central nervous system concentrations of cyclooxygenase-2 inhibitors in humans. ANESTHESIOLOGY 2005; 102:409-15