메뉴 건너뛰기




Volumn 59, Issue 3, 2006, Pages 444-447

Expectations and challenges in the therapeutic use of neurotrophic factors

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; FLUORINE 18; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIC FACTOR; NEURTURIN; SOMATOMEDIN C;

EID: 33644823299     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20794     Document Type: Editorial
Times cited : (17)

References (26)
  • 1
    • 33644833272 scopus 로고    scopus 로고
    • Randomized controlled trial of intraputamenal Glial cell line-derived neurotrophic factor infusion in Parkinson disease
    • Lang AE, Gill S, Patel NK, et al. Randomized controlled trial of intraputamenal Glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 2006;59:459-466.
    • (2006) Ann Neurol , vol.59 , pp. 459-466
    • Lang, A.E.1    Gill, S.2    Patel, N.K.3
  • 2
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin LF, Doherty DH, Lile JD, et al. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993;260:1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3
  • 3
    • 0037911432 scopus 로고    scopus 로고
    • Intraputamenal infusion of GDNF in aged rhesus monkeys: Distribution and dopaminergic effects
    • Ai Y, Markesbery W, Zhang Z, et al. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. J Comp Neurol 2003;461:250-261.
    • (2003) J Comp Neurol , vol.461 , pp. 250-261
    • Ai, Y.1    Markesbery, W.2    Zhang, Z.3
  • 4
    • 0037336930 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys
    • Grondin R, Cass WA, Zhang Z, et al. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. J Neurosci 2003;23:1974-1980.
    • (2003) J Neurosci , vol.23 , pp. 1974-1980
    • Grondin, R.1    Cass, W.A.2    Zhang, Z.3
  • 5
    • 0036787532 scopus 로고    scopus 로고
    • Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
    • Grondin R, Zhang Z, Yi A, et al. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 2002;125:2191-2201.
    • (2002) Brain , vol.125 , pp. 2191-2201
    • Grondin, R.1    Zhang, Z.2    Yi, A.3
  • 6
    • 20744435383 scopus 로고    scopus 로고
    • Molecular pathophysiology of Parkinson's disease
    • Moore DJ, West AB, Dawson VL, et al. Molecular pathophysiology of Parkinson's disease. Annu Rev Neurosci 2005;28:57-87.
    • (2005) Annu Rev Neurosci , vol.28 , pp. 57-87
    • Moore, D.J.1    West, A.B.2    Dawson, V.L.3
  • 7
    • 0037435511 scopus 로고    scopus 로고
    • Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
    • Nutt JG, Burchiel KJ, Comella CL, et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 2003;60:69-73.
    • (2003) Neurology , vol.60 , pp. 69-73
    • Nutt, J.G.1    Burchiel, K.J.2    Comella, C.L.3
  • 8
    • 0038249170 scopus 로고    scopus 로고
    • Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
    • Gill SS, Patel NK, Hotton GR, et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 2003;9:589-595.
    • (2003) Nat Med , vol.9 , pp. 589-595
    • Gill, S.S.1    Patel, N.K.2    Hotton, G.R.3
  • 9
    • 13144282676 scopus 로고    scopus 로고
    • Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study
    • Patel NK, Bunnage M, Plaha P, et al. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann Neurol 2005;57:298-302.
    • (2005) Ann Neurol , vol.57 , pp. 298-302
    • Patel, N.K.1    Bunnage, M.2    Plaha, P.3
  • 10
    • 22544461907 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain
    • Love S, Plaha P, Patel NK, et al. Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 2005;11:703-704.
    • (2005) Nat Med , vol.11 , pp. 703-704
    • Love, S.1    Plaha, P.2    Patel, N.K.3
  • 11
    • 14844311296 scopus 로고    scopus 로고
    • Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
    • Slevin JT, Gerhardt GA, Smith CD, et al. Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 2005;102:216-222.
    • (2005) J Neurosurg , vol.102 , pp. 216-222
    • Slevin, J.T.1    Gerhardt, G.A.2    Smith, C.D.3
  • 12
    • 23244453160 scopus 로고    scopus 로고
    • Trophic factor distribution predicts functional recovery in parkinsonian monkeys
    • Gash DM, Zhang Z, Ai Y, et al. Trophic factor distribution predicts functional recovery in parkinsonian monkeys. Ann Neurol 2005;58:224-233.
    • (2005) Ann Neurol , vol.58 , pp. 224-233
    • Gash, D.M.1    Zhang, Z.2    Ai, Y.3
  • 13
    • 11144353880 scopus 로고    scopus 로고
    • Effects of perceived treatment on quality of life and medical outcomes in a double-blind placebo surgery trial
    • McRae C, Cherin E, Yamazaki TG, et al. Effects of perceived treatment on quality of life and medical outcomes in a double-blind placebo surgery trial. Arch Gen Psychiatry 2004;61:412-420.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 412-420
    • McRae, C.1    Cherin, E.2    Yamazaki, T.G.3
  • 14
    • 12844287442 scopus 로고    scopus 로고
    • Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease
    • Eslamboli A, Georgievska B, Ridley RM, et al. Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease. J Neurosci 2005;25:769-777.
    • (2005) J Neurosci , vol.25 , pp. 769-777
    • Eslamboli, A.1    Georgievska, B.2    Ridley, R.M.3
  • 15
    • 0029827559 scopus 로고    scopus 로고
    • Neurturin, a relative of glial-cell-line-derived neurotrophic factor
    • Kotzbauer PT, Lampe PA, Heuckeroth RO, et al. Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature 1996;384:467-470.
    • (1996) Nature , vol.384 , pp. 467-470
    • Kotzbauer, P.T.1    Lampe, P.A.2    Heuckeroth, R.O.3
  • 16
    • 0031019795 scopus 로고    scopus 로고
    • Dopaminergic neurons protected from degeneration by GDNF gene therapy
    • Choi-Lundberg DL, Lin Q, Chang YN, et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 1997;275:838-841.
    • (1997) Science , vol.275 , pp. 838-841
    • Choi-Lundberg, D.L.1    Lin, Q.2    Chang, Y.N.3
  • 17
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
    • Kordower JH, Emborg ME, Bloch J, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 2000;290:767-773.
    • (2000) Science , vol.290 , pp. 767-773
    • Kordower, J.H.1    Emborg, M.E.2    Bloch, J.3
  • 18
    • 23644452944 scopus 로고    scopus 로고
    • Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct
    • Fjord-Larsen L, Johansen JL, Kusk P, et al. Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct. Exp Neurol 2005;195:49-60.
    • (2005) Exp Neurol , vol.195 , pp. 49-60
    • Fjord-Larsen, L.1    Johansen, J.L.2    Kusk, P.3
  • 19
    • 21044458854 scopus 로고    scopus 로고
    • A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease
    • Tuszynski MH, Thal L, Pay M, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nat Med 2005;11:551-555.
    • (2005) Nat Med , vol.11 , pp. 551-555
    • Tuszynski, M.H.1    Thal, L.2    Pay, M.3
  • 20
    • 0031722582 scopus 로고    scopus 로고
    • A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis
    • European ALS/IGF-I Study Group
    • Borasio GD, Robberecht W, Leigh PN, et al. A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group. Neurology 1998;51:583-586.
    • (1998) Neurology , vol.51 , pp. 583-586
    • Borasio, G.D.1    Robberecht, W.2    Leigh, P.N.3
  • 21
    • 6844266272 scopus 로고    scopus 로고
    • Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study
    • The North America ALS/IGF-I Study Group
    • Lai EC, Felice KJ, Festoff BW, et al. Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group. Neurology 1997;49:1621-1630.
    • (1997) Neurology , vol.49 , pp. 1621-1630
    • Lai, E.C.1    Felice, K.J.2    Festoff, B.W.3
  • 22
    • 2442646665 scopus 로고    scopus 로고
    • A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
    • ALS CNTF Treatment Study Group
    • A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group. Neurology 1996;46:1244-1249.
    • (1996) Neurology , vol.46 , pp. 1244-1249
  • 23
    • 0344076149 scopus 로고    scopus 로고
    • A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)
    • A controlled trial of recombinant methionyl human BDNF in ALS: the BDNF Study Group (Phase III). Neurology 1999;52:1427-1433.
    • (1999) Neurology , vol.52 , pp. 1427-1433
  • 26
    • 5644295321 scopus 로고    scopus 로고
    • Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: Results of a phase I study
    • Bloch J, Bachoud-Levi AC, Deglon N, et al. Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. Hum Gene Ther 2004;15:968-975.
    • (2004) Hum Gene Ther , vol.15 , pp. 968-975
    • Bloch, J.1    Bachoud-Levi, A.C.2    Deglon, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.