Non-steroidal and steroidal anti-inflammatory drugs vary in their modulation of dendritic cell function in the elicitation phase of allergic contact dermatitis

Experimental Dermatology

Volumn 15, Issue 4, 2006, Pages 322-329

  Bäumer, Wolfgang ^a   Krekeler, S ^a   DeVries, V C ^b   Niedorf, F ^a   Tschernig, T ^b   Kietzmann, M ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Acetylsalicylic acid; Allergic contact dermatitis; Dendritic cells; Diflorasone diacetate; Indomethacin

Indexed keywords

ACETYLSALICYLIC ACID; DIFLORASONE DIACETATE; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; STEROID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; DOSE RESPONSE; DRUG ABSORPTION; DRUG EFFICACY; DRUG PENETRATION; FEMALE; IMMUNOMODULATION; LYMPHATIC DRAINAGE; MOUSE; NONHUMAN; SKIN ALLERGY; SYSTEMIC THERAPY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BETAMETHASONE; CELL MOVEMENT; CELLS, CULTURED; DENDRITIC CELLS; DERMATITIS, ALLERGIC CONTACT; DINOPROSTONE; FEMALE; IMMUNOHISTOCHEMISTRY; INDOMETHACIN; LANGERHANS CELLS; LYMPH NODES; MICE; MICE, INBRED BALB C; PROTEIN-SERINE-THREONINE KINASES;

EID: 33644815419     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2006.00412.x     Document Type: Article

References (36)

1. Tarayre J P, Aliaga M, Villanova G et al. Pharmacological comparison of the immune and non-immune inflammations induced by picryl chloride and oxazolone in mice. Arch Int Pharmacodyn Ther 1984: 269: 153-166. 153-166.
2. Meurer R, Opas E E, Humes J L. Effects of cyclooxygenase and lipoxygenase inhibitors on inflammation associated with oxazolone-induced delayed hypersensitivity. Biochem Pharmacol 1988: 37: 3511-3514.
3. Rao T S, Currie J L, Shaffer A F, Isakson P C. Comparative evaluation of arachidonic acid (AA)- and tetradecanoylphorbol acetate (TPA)-induced dermal inflammation. Inflammation 1993: 17: 723-741.
4. Baumer W, Sulzle B, Weigt H et al. Cilomilast, tacrolimus and rapamycin modulate dendritic cell function in the elicitation phase of allergic contact dermatitis. Br J Dermatol 2005: 153: 136-144.
5. Kopp E, Ghosh S. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science 1994: 265: 956-959.
6. Yin M J, Yamamoto Y, Gaynor R B. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I (kappa) B kinase-beta. Nature 1998: 396: 77-80.
7. Hackstein H, Morelli A E, Larregina A T et al. Aspirin inhibits in vitro maturation and in vivo immunostimulatory function of murine myeloid dendritic cells. J Immunol 2001: 166: 7053-7062.
8. Matasic R, Dietz A B, Vuk-Pavlovic S. Cyclooxygenase-independent inhibition of dendritic cell maturation by aspirin. Immunology 2000: 101: 53-60.
9. Kabashima K, Sakata D, Nagamachi M, Miyachi Y, Inaba K, Narumiya S. Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. Nat Med 2003: 9: 744-749.
10. Baumer W, Gorr G, Hoppmann J, Ehinger A M, Rundfeldt C, Kietzmann M. AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis. J Pharm Pharmacol 2003: 55: 1107-1114.
11. Baumer W, Seegers U, Braun M, Tschernig T, Kietzmann M. TARC and RANTES, but not CTACK, are induced in two models of allergic contact dermatitis. Effects of cilomilast and diflorasone diacetate on T-cell-attracting chemokines. Br J Dermatol 2004: 151: 823-830.
12. Lutz M B, Kukutsch N, Ogilvie A L et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 1999: 223: 77-92.
13. Baumer W, Tschernig T, Sulzle B, Seegers U, Luhrmann A, Kietzmann M. Effects of cilomilast on dendritic cell function in contact sensitivity and dendritic cell migration through skin. Eur J Pharmacol 2003: 481: 271-279.
14. Ehling G, Hecht M, Heusener A et al. An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: First round. Toxicology 2005: 212: 60-68.
15. Puignero V, Queralt J. Effect of topically applied cyclooxygenase-2-selective inhibitors on arachidonic acid- and tetradecanoylphorbol acetate-induced dermal inflammation in the mouse. Inflammation 1997: 21: 431-442.
16. Ortner U, Inaba K, Koch F et al. An improved isolation method for murine migratory cutaneous dendritic cells. J Immunol Methods 1996: 193: 71-79.
17. Kimber I, Basketter D A, Gerberick G F, Dearman R J. Allergic contact dermatitis. Int Immunopharmacol 2002: 2: 201-211.
18. Krasteva M, Kehren J, Ducluzeau M T et al. Contact dermatitis I. Pathophysiology of contact sensitivity. Eur J Dermatol 1999: 9: 65-77.
19. Becker D, Knop J. Mechanism in allergic contact dermatitis. Exp Dermatol 1993: 2: 63-69.
20. Stoitzner P, Holzmann S, McLellan A D et al. Visualization and characterization of migratory Langerhans cells in murine skin and lymph nodes by antibodies against Langerin/CD207. J Invest Dermatol 2003: 120: 266-274.
21. Stoitzner P, Tripp C H, Douillard P, Saeland S, Romani N. Migratory Langerhans cells in mouse lymph nodes in steady state and inflammation. J Invest Dermatol 2005: 125: 116-125.
22. Grabbe S, Schwarz T. Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol Today 1998: 19: 37-44.
23. Grabbe S, Steinbrink K, Steinert M, Luger T A, Schwarz T. Removal of the majority of epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity. J Immunol 1995: 155: 4207-4217.
24. Bennett C L, van Rijn E, Jung S et al. Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. J Cell Biol 2005: 169: 569-576.
25. Araki M, Imafuku S, Furue M, Shimada S, Tamaki K. Activation pattern of Langerhans cells in the afferent and efferent phases of contact hypersensitivity. J Investig Dermatol Symp Proc 1999: 4: 164-168.
26. Ohl L, Mohaupt M, Czeloth N et al. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 2004: 21: 279-288.
27. Ruedl C, Koebel P, Bachmann M, Hess M, Karjalainen K. Anatomical origin of dendritic cells determines their life span in peripheral lymph nodes. J Immunol 2000: 165: 4910-4916.
28. Scandella E, Men Y, Gillessen S, Forster R, Groettrup M. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 2002: 100: 1354-1361.
29. Ratzinger G, Stoitzner P, Ebner S et al. Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin. J Immunol 2002: 168: 4361-4371.
30. Murono S, Yoshizaki T, Sato H, Takeshita H, Furukawa M, Pagano J S. Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression. Cancer Res 2000: 60: 2555-2561.
31. Zhang Y, McCluskey K, Fujii K, Wahl L M. Differential regulation of monocyte matrix metalloproteinase and TIMP-1 production by TNF-alpha, granulocyte-macrophage CSF, and IL-1 beta through prostaglandin-dependent and - independent mechanisms. J Immunol 1998: 161: 3071-3076.
32. Takada Y, Bhardwaj A, Potdar P, Aggarwal B B. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene 2004: 23: 9247-9258.
33. Preciado D, Caicedo E, Jhanjee R et al. Pseudomonas aeruginosa lipopolysaccharide induction of keratinocyte proliferation, NF-kappa B, and cyclin D1 is inhibited by indomethacin. J Immunol 2005: 174: 2964-2973.
34. Gomez A, Florido J F, Quiralte J, Martin A E, Saenz de San P B. Allergic contact dermatitis due to indomethacin and diclofenac. Contact Dermatitis 2000: 43: 59.
35. Cumberbatch M, Dearman R J, Kimber I. Inhibition by dexamethasone of Langerhans cell migration: Influence of epidermal cytokine signals. Immunopharmacology 1999: 41: 235-243.
36. Homey B, Schuppe H C, Assmann T et al. A local lymph node assay to analyse immunosuppressive effects of topically applied drugs. Eur J Pharmacol 1997: 325: 199-207.