Characterization of dual substrate binding sites in the homodimeric structure of Escherichia coli mRNA interferase MazF

Journal of Molecular Biology

Volumn 357, Issue 1, 2006, Pages 139-150

  Li, Guang Yao ^a   Zhang, Yonglong ^b   Chan, Mitchell C Y ^a   Mal, Tapas K ^a   Hoeflich, Klaus P ^a,c   Inouye, Masayori ^b   Ikura, Mitsuhiko ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c GENENTECH INC   (United States)

Author keywords

Addiction module; MazE; MazF; mRNA interferase; NMR spectroscopy

Indexed keywords

CARBOXY TERMINAL TELOPEPTIDE; HISTIDINE; HOMODIMER; MESSENGER RNA; PROTEIN MAZE; PROTEIN MAZF; RIBONUCLEASE; SINGLE STRANDED DNA; TOXIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; DNA BINDING; DNA PROTEIN COMPLEX; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HYDROPHOBICITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; RNA INTERFERENCE; SEQUENTIAL ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33644777837     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.12.035     Document Type: Article

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