Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment: Structure, thermodynamics of binding, stability, and influence on interactions with DNA

Journal of Biological Chemistry

Volumn 278, Issue 16, 2003, Pages 14101-14111

  Lah, Jurij ^a,b   Marianovsky, Irina ^c   Glaser, Gad ^c   Engelberg Kulka, Hanna ^c   Kinne, Jörg ^d   Wyns, Lode ^a   Loris, Remy ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d CENTRAL VETERINARY RESEARCH LABORATORY   (United Arab Emirates)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CELLS; CONFORMATIONS; CRYSTALLIZATION; DIMERS; ENTHALPY; GROWTH KINETICS; MONOMERS;

ANTIDOTES;

DNA;

ANTIBODY; CABMAZ1 PROTEIN; DNA; DNA FRAGMENT; MAZE PROTEIN; PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; ESCHERICHIA COLI PROTEIN; IMMUNOGLOBULIN FRAGMENT; MAZE PROTEIN, E COLI; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CAMEL; CELL DEATH; DNA STRUCTURE; ENTHALPY; ESCHERICHIA COLI; MICROCALORIMETRY; MOLECULAR RECOGNITION; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SPECTROSCOPY; ANIMAL; BIOCHEMISTRY; CALORIMETRY; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DIMERIZATION; ENTROPY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; TEMPERATURE; THERMODYNAMICS; TIME;

CAMELIDAE; CAMELUS DROMEDARIUS; ESCHERICHIA COLI; PROKARYOTA;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOCHEMISTRY; CALORIMETRY; CALORIMETRY, DIFFERENTIAL SCANNING; CAMELS; CIRCULAR DICHROISM; DIMERIZATION; DNA; DNA-BINDING PROTEINS; ENTROPY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IMMUNOGLOBULIN FRAGMENTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE; THERMODYNAMICS; TIME FACTORS;

EID: 0037515721     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209855200     Document Type: Article

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