메뉴 건너뛰기




Volumn 7, Issue 8, 2005, Pages 788-798

Cooperative interactions of HER-2 and HPV-16 oncoproteins in the malignant transformation of human mammary epithelial cells

Author keywords

EGFR; Her 2; HPV E6; HPV E7; Human breast cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEFITINIB; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ONCOGENE PROTEIN E7, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOPROTEIN; REPRESSOR PROTEIN;

EID: 33644698719     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.05106     Document Type: Article
Times cited : (29)

References (52)
  • 1
    • 0034666345 scopus 로고    scopus 로고
    • Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): A study of incidence and correlation with outcome in breast cancer
    • Thor AD, Liu S, Edgerton S, Moore D II, Kasowitz KM, Benz CC, Stern DF, and DiGiovanna MP (2000). Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancer. J Clin Oncol 18, 3230-3239.
    • (2000) J Clin Oncol , vol.18 , pp. 3230-3239
    • Thor, A.D.1    Liu, S.2    Edgerton, S.3    Moore II, D.4    Kasowitz, K.M.5    Benz, C.C.6    Stern, D.F.7    DiGiovanna, M.P.8
  • 2
    • 0035227887 scopus 로고    scopus 로고
    • Prognostic and predictive value of c-erbB-2 (HER2/neu) gene amplification in human breast cancer
    • Tsuda HH (2001). Prognostic and predictive value of c-erbB-2 (HER2/neu) gene amplification in human breast cancer. Breast Cancer 8, 38-44.
    • (2001) Breast Cancer , vol.8 , pp. 38-44
    • Tsuda, H.H.1
  • 4
    • 0028796895 scopus 로고
    • NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells
    • Marte BM, Grausporta D, Jeschke M, Fabbro D, Hynes NE, and Taverna D (1995). NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells. Oncogene 10, 167-175.
    • (1995) Oncogene , vol.10 , pp. 167-175
    • Marte, B.M.1    Grausporta, D.2    Jeschke, M.3    Fabbro, D.4    Hynes, N.E.5    Taverna, D.6
  • 5
    • 0028823802 scopus 로고
    • Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2
    • Beerli RR, Grausporta D, Woodscook K, Chen XM, Yarden Y, and Hynes NE (1995). Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2. Mol Cell Biol 15, 6496-6505.
    • (1995) Mol Cell Biol , vol.15 , pp. 6496-6505
    • Beerli, R.R.1    Grausporta, D.2    Woodscook, K.3    Chen, X.M.4    Yarden, Y.5    Hynes, N.E.6
  • 8
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of inter-receptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar E, Waterman H, Chen X, Levkowitz G, Karunagaran D, Lavi S, Ratzkin B, and Yarden Y (1996). A hierarchical network of inter-receptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 16, 5276-5287.
    • (1996) Mol Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3    Levkowitz, G.4    Karunagaran, D.5    Lavi, S.6    Ratzkin, B.7    Yarden, Y.8
  • 9
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • GrausPorta D, Beerli RR, Daly JM, and Hynes NE (1997). ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16, 1647-1655.
    • (1997) EMBO J , vol.16 , pp. 1647-1655
    • GrausPorta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 10
    • 0030795612 scopus 로고    scopus 로고
    • The erbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand - Receptor interactions
    • Alroy I and Yarden Y (1997). The erbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand - receptor interactions. FEBS Lett 410, 83-86.
    • (1997) FEBS Lett , vol.410 , pp. 83-86
    • Alroy, I.1    Yarden, Y.2
  • 11
    • 0031840484 scopus 로고    scopus 로고
    • ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
    • Olayioye MA, Graus-Porta D, Beerli RR, Rohrer J, Gay B, and Hynes NE (1998). ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner. Mol Cell Biol, 5042-5051.
    • (1998) Mol Cell Biol , pp. 5042-5051
    • Olayioye, M.A.1    Graus-Porta, D.2    Beerli, R.R.3    Rohrer, J.4    Gay, B.5    Hynes, N.E.6
  • 12
    • 0033608993 scopus 로고    scopus 로고
    • The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma - Derived growth factors
    • Klapper LN, Glathe S, Vaisman N, Hynes NE, Andrews GC, Sela M, and Yarden Y (1999). The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma - derived growth factors. Proc Natl Acad Sci USA 96, 4995-5000.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4995-5000
    • Klapper, L.N.1    Glathe, S.2    Vaisman, N.3    Hynes, N.E.4    Andrews, G.C.5    Sela, M.6    Yarden, Y.7
  • 13
    • 0033542379 scopus 로고    scopus 로고
    • NDF/heregulin - Induced cell cycle changes and apoptosis in breast tumour cells: Role of PI3 kinase and p38 MAP kinase pathways
    • Daly JM, Olayioye MA, Wong AM, Neve R, Lane HA, Maurer FG, and Hynes NE (1999). NDF/heregulin - induced cell cycle changes and apoptosis in breast tumour cells: role of PI3 kinase and p38 MAP kinase pathways. Oncogene 18, 3440-3451.
    • (1999) Oncogene , vol.18 , pp. 3440-3451
    • Daly, J.M.1    Olayioye, M.A.2    Wong, A.M.3    Neve, R.4    Lane, H.A.5    Maurer, F.G.6    Hynes, N.E.7
  • 14
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas CF III, and Hynes NE (2003). The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. PNAS 100, 8933-8938.
    • (2003) PNAS , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3    Koziczak, M.4    Barbas III, C.F.5    Hynes, N.E.6
  • 15
    • 0345178412 scopus 로고
    • Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract
    • Hammond SL, Ham RG, and Stampfer MR (1984). Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc Natl Acad Sci USA 81, 5435-5439.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5435-5439
    • Hammond, S.L.1    Ham, R.G.2    Stampfer, M.R.3
  • 16
    • 0021795811 scopus 로고
    • Primary culture and serial passage of normal and carcinogen-treated rat mammary epithelial cells in vitro
    • Ethier SP (1985). Primary culture and serial passage of normal and carcinogen-treated rat mammary epithelial cells in vitro. J Natl Cancer Inst 74, 1307-1318.
    • (1985) J Natl Cancer Inst , vol.74 , pp. 1307-1318
    • Ethier, S.P.1
  • 17
    • 0025678124 scopus 로고
    • The influence of growth factors on the proliferative potential of normal and primary breast cancer - Derived human breast epithelial cells
    • Ethier SP, Summerfelt RM, Cundiff KC, and Asch BB (1990). The influence of growth factors on the proliferative potential of normal and primary breast cancer - derived human breast epithelial cells. Breast Cancer Res Treat 17, 221-230.
    • (1990) Breast Cancer Res Treat , vol.17 , pp. 221-230
    • Ethier, S.P.1    Summerfelt, R.M.2    Cundiff, K.C.3    Asch, B.B.4
  • 18
    • 0027283717 scopus 로고
    • Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle
    • Stampfer MR, Pan CH, Hosoda J, Bartholomew J, Mendelsohn J, and Yaswen P (1993). Blockage of EGF receptor signal transduction causes reversible arrest of normal and immortal human mammary epithelial cells with synchronous reentry into the cell cycle. Exp Cell Res 208, 175-188.
    • (1993) Exp Cell Res , vol.208 , pp. 175-188
    • Stampfer, M.R.1    Pan, C.H.2    Hosoda, J.3    Bartholomew, J.4    Mendelsohn, J.5    Yaswen, P.6
  • 19
    • 0029029137 scopus 로고
    • Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells
    • Ram TG, Kokeny KE, Dilts CA, and Ethier SP (1995). Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells. J Cell Physiol 163, 589-596.
    • (1995) J Cell Physiol , vol.163 , pp. 589-596
    • Ram, T.G.1    Kokeny, K.E.2    Dilts, C.A.3    Ethier, S.P.4
  • 20
    • 0030065440 scopus 로고    scopus 로고
    • Immortalization of human mammary epithelial cells transfected with mutant p53 (273(his))
    • Gollahon LS and Shay JW (1996). Immortalization of human mammary epithelial cells transfected with mutant p53 (273(his)). Oncogene 12, 715-725.
    • (1996) Oncogene , vol.12 , pp. 715-725
    • Gollahon, L.S.1    Shay, J.W.2
  • 21
    • 0030004489 scopus 로고    scopus 로고
    • Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids
    • Wright WE, Brasiskyte D, Piatyszek MA, and Shay JW (1996). Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids. EMBO J 15, 1734-1741.
    • (1996) EMBO J , vol.15 , pp. 1734-1741
    • Wright, W.E.1    Brasiskyte, D.2    Piatyszek, M.A.3    Shay, J.W.4
  • 22
    • 0023616116 scopus 로고
    • Importance of extended growth potential and growth factor independence on tial in vivo neoplastic potential of primary rat mammary carcinoma cells
    • Ethier SP and Cundiff KC (1987). Importance of extended growth potential and growth factor independence on tial in vivo neoplastic potential of primary rat mammary carcinoma cells. Cancer Res 47, 5316-5322.
    • (1987) Cancer Res , vol.47 , pp. 5316-5322
    • Ethier, S.P.1    Cundiff, K.C.2
  • 23
    • 0026246951 scopus 로고
    • Secretion of an epidermal growth factor - Like growth factor by epidermal growth factor - independent rat mammary carcinoma cells
    • Ethier SP, Moorthy R, and Dilts CA (1991). Secretion of an epidermal growth factor - like growth factor by epidermal growth factor - independent rat mammary carcinoma cells. Cell Growth Differ 2, 593-602.
    • (1991) Cell Growth Differ , vol.2 , pp. 593-602
    • Ethier, S.P.1    Moorthy, R.2    Dilts, C.A.3
  • 24
    • 0029935297 scopus 로고    scopus 로고
    • Growth factor independent proliferation of rat mammary carcinoma cells by autocrine secretion of neu-differentiation factor/heregulin and transforming growth factor alpha
    • Ethier SP, Langton BC, and Dilts CA (1996). Growth factor independent proliferation of rat mammary carcinoma cells by autocrine secretion of neu-differentiation factor/heregulin and transforming growth factor alpha. Mol Carcinog 15, 134-143.
    • (1996) Mol Carcinog , vol.15 , pp. 134-143
    • Ethier, S.P.1    Langton, B.C.2    Dilts, C.A.3
  • 25
    • 0029929513 scopus 로고    scopus 로고
    • Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine phosphorylated erbB-2
    • Ram TG, Dilts CA, Dziubinski ML, Pierce LJ, and Ethier SP (1996). Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine phosphorylated erbB-2. Mol Carcinog 15, 227-2386.
    • (1996) Mol Carcinog , vol.15 , pp. 227-2386
    • Ram, T.G.1    Dilts, C.A.2    Dziubinski, M.L.3    Pierce, L.J.4    Ethier, S.P.5
  • 26
    • 0033304746 scopus 로고    scopus 로고
    • ErbB-2 overexpression in human mammary epithelial cells confers growth factor independence
    • Woods Ignatoski KM, LaPointe AJ, Radany EH, and Ethier SP (1999). ErbB-2 overexpression in human mammary epithelial cells confers growth factor independence. Endocrinology 140, 3615-3622.
    • (1999) Endocrinology , vol.140 , pp. 3615-3622
    • Woods Ignatoski, K.M.1    LaPointe, A.J.2    Radany, E.H.3    Ethier, S.P.4
  • 27
    • 0000446084 scopus 로고    scopus 로고
    • ERBB-2 overexpression confers PI 3′-kinase - Dependent invasion capacity on human mammary epithelial cells
    • Woods Ignatoski KM, Maehama T, Markwart SM, Dixon JE, Livant DL, and Ethier SP (2000). ERBB-2 overexpression confers PI 3′-kinase - dependent invasion capacity on human mammary epithelial cells. Br J Cancer 82, 666-674.
    • (2000) Br J Cancer , vol.82 , pp. 666-674
    • Woods Ignatoski, K.M.1    Maehama, T.2    Markwart, S.M.3    Dixon, J.E.4    Livant, D.L.5    Ethier, S.P.6
  • 28
    • 9244237086 scopus 로고    scopus 로고
    • Integrin receptors regulate MMP1 dependent invasion by breast cancer cells and by mammary epithelial cells
    • Jia Y, Markwart SM, Gransden LA, Woods Ignatoski KM, Ethier SP, and Livant DL (2004). Integrin receptors regulate MMP1 dependent invasion by breast cancer cells and by mammary epithelial cells. Cancer Res 64, 8674-8681.
    • (2004) Cancer Res , vol.64 , pp. 8674-8681
    • Jia, Y.1    Markwart, S.M.2    Gransden, L.A.3    Woods Ignatoski, K.M.4    Ethier, S.P.5    Livant, D.L.6
  • 29
    • 0037313618 scopus 로고    scopus 로고
    • Coordinated regulation of life and death by Rb
    • Chau BN and Wang JYJ (2003). Coordinated regulation of life and death by Rb. Nat Rev Cancer 3, 130-138.
    • (2003) Nat Rev Cancer , vol.3 , pp. 130-138
    • Chau, B.N.1    Wang, J.Y.J.2
  • 30
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr CJ (2004). Principles of tumor suppression. Cell 116, 235-246.
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 31
    • 0033615732 scopus 로고    scopus 로고
    • Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7
    • Yokouchi M, Kondo T, Houghton A, Bartkiewicz M, Horne WC, Zhang H, Yoshimura A, and Baron R (1999). Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7. J Biol Chem 274, 31707-31712.
    • (1999) J Biol Chem , vol.274 , pp. 31707-31712
    • Yokouchi, M.1    Kondo, T.2    Houghton, A.3    Bartkiewicz, M.4    Horne, W.C.5    Zhang, H.6    Yoshimura, A.7    Baron, R.8
  • 32
    • 0035893560 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2) - Overexpressing breast cancer cells in vitro and in vivo
    • Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF, and Arteaga CL (2001). Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2) - overexpressing breast cancer cells in vitro and in vivo. Cancer Res 61, 8887-8895.
    • (2001) Cancer Res , vol.61 , pp. 8887-8895
    • Moulder, S.L.1    Yakes, F.M.2    Muthuswamy, S.K.3    Bianco, R.4    Simpson, J.F.5    Arteaga, C.L.6
  • 33
    • 0035476803 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
    • Moasser M, Basso A, Averbuch SD, and Rosen N (2001). The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res 61, 7184-7188.
    • (2001) Cancer Res , vol.61 , pp. 7184-7188
    • Moasser, M.1    Basso, A.2    Averbuch, S.D.3    Rosen, N.4
  • 34
    • 0037388251 scopus 로고    scopus 로고
    • ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells
    • Anido J, Matar P, Albanell J, Guzmán M, Rojo F, Arribas J, Averbuch S, and Baselga J (2003). ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin Cancer Res 9, 1274-1283.
    • (2003) Clin Cancer Res , vol.9 , pp. 1274-1283
    • Anido, J.1    Matar, P.2    Albanell, J.3    Guzmán, M.4    Rojo, F.5    Arribas, J.6    Averbuch, S.7    Baselga, J.8
  • 35
    • 0038356604 scopus 로고    scopus 로고
    • EGFR, HER2/neu, Cyclin D1, p21 and p53 in correlation to cell proliferation and steroid hormone receptor status in ductal carcinoma in situ of the breast
    • Lebeau A, Unholzer A, Amann G, Kronawitter M, Bauerfeind I, Sendelhofert A, Iff A, and Löhrs U (2003). EGFR, HER2/neu, Cyclin D1, p21 and p53 in correlation to cell proliferation and steroid hormone receptor status in ductal carcinoma in situ of the breast. Breast Cancer Res Treat 79, 187-198.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 187-198
    • Lebeau, A.1    Unholzer, A.2    Amann, G.3    Kronawitter, M.4    Bauerfeind, I.5    Sendelhofert, A.6    Iff, A.7    Löhrs, U.8
  • 36
    • 0041322734 scopus 로고    scopus 로고
    • Co-expression of ErbB-family members in human breast cancer: HER2/neu is the preferred dimerization candidate in nodal-positive tumors
    • Hudelist G, Singer CF, Manavi M, Pischinger K, Kubista E, and Czerwenka K (2003). Co-expression of ErbB-family members in human breast cancer: HER2/neu is the preferred dimerization candidate in nodal-positive tumors. Breast Cancer Res Treat 80, 353-361.
    • (2003) Breast Cancer Res Treat , vol.80 , pp. 353-361
    • Hudelist, G.1    Singer, C.F.2    Manavi, M.3    Pischinger, K.4    Kubista, E.5    Czerwenka, K.6
  • 37
    • 0036145181 scopus 로고    scopus 로고
    • EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival
    • Suo Z, Risberg B, Kalsson MG, Willman K, Tierens A, Skovlund E, and Nesland JM (2002). EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival. J Pathol 196, 17-25.
    • (2002) J Pathol , vol.196 , pp. 17-25
    • Suo, Z.1    Risberg, B.2    Kalsson, M.G.3    Willman, K.4    Tierens, A.5    Skovlund, E.6    Nesland, J.M.7
  • 41
    • 0037352352 scopus 로고    scopus 로고
    • p38MAPK induces cell surface a4 integrin down-regulation to facilitate erbB-2 - Mediated invasion
    • Woods Ignatoski KM, Livant DL, Grewal NK, Markwart S, and Ethier SP (2003). p38MAPK induces cell surface a4 integrin down-regulation to facilitate erbB-2 - mediated invasion. Neoplasia 5, 128-134.
    • (2003) Neoplasia , vol.5 , pp. 128-134
    • Woods Ignatoski, K.M.1    Livant, D.L.2    Grewal, N.K.3    Markwart, S.4    Ethier, S.P.5
  • 42
    • 0037931402 scopus 로고    scopus 로고
    • Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: Distribution of homo- and heterodimers depends on relative HER2 levels
    • Hendriks BS, Opresko LK, Wiley HS, and Lauffenburger D (2003). Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels. J Biol Chem 278, 23343-23351.
    • (2003) J Biol Chem , vol.278 , pp. 23343-23351
    • Hendriks, B.S.1    Opresko, L.K.2    Wiley, H.S.3    Lauffenburger, D.4
  • 44
    • 0037330709 scopus 로고    scopus 로고
    • Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins
    • Helt A-M and Galloway DA (2003). Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins. Carcinogenesis 24, 159-169.
    • (2003) Carcinogenesis , vol.24 , pp. 159-169
    • Helt, A.-M.1    Galloway, D.A.2
  • 45
    • 0346485798 scopus 로고    scopus 로고
    • Cytoplasmic p21WAF1/CIP1 expression is correlated with HER2/ neu in breast cancer and is an independent predictor of prognosis
    • Winters ZE, Leek RD, Bradburn MJ, Norbury CJ, and Harris AL (2003). Cytoplasmic p21WAF1/CIP1 expression is correlated with HER2/ neu in breast cancer and is an independent predictor of prognosis. Br Cancer Res 5, R242-R249.
    • (2003) Br Cancer Res , vol.5
    • Winters, Z.E.1    Leek, R.D.2    Bradburn, M.J.3    Norbury, C.J.4    Harris, A.L.5
  • 46
    • 4344637857 scopus 로고    scopus 로고
    • p27 deregulation in breast cancer: Prognostic significance and implications for therapy
    • Alkarain A, Jordan R, and Slingerland J (2004). p27 deregulation in breast cancer: prognostic significance and implications for therapy. J Mammary Gland Biol Neoplasia 9, 67-80.
    • (2004) J Mammary Gland Biol Neoplasia , vol.9 , pp. 67-80
    • Alkarain, A.1    Jordan, R.2    Slingerland, J.3
  • 47
    • 0028169371 scopus 로고
    • Prad-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas
    • Jares P, Fernandez PL, Campo E, Nadal A, Bosch F, Aiza G, Nayach I, Traserra J, and Cardesa A (1994). Prad-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas. Cancer Res 54, 4813-4817.
    • (1994) Cancer Res , vol.54 , pp. 4813-4817
    • Jares, P.1    Fernandez, P.L.2    Campo, E.3    Nadal, A.4    Bosch, F.5    Aiza, G.6    Nayach, I.7    Traserra, J.8    Cardesa, A.9
  • 48
    • 0028970951 scopus 로고
    • Oncogenic aberrations of p16INK4/CDKN2 and cyclin D1 cooperate to deregulate G1 control
    • Lukas J, Aagaard L, Strauss M, and Bartek J (1995). Oncogenic aberrations of p16INK4/CDKN2 and cyclin D1 cooperate to deregulate G1 control. Cancer Res, 4818-4823.
    • (1995) Cancer Res , pp. 4818-4823
    • Lukas, J.1    Aagaard, L.2    Strauss, M.3    Bartek, J.4
  • 49
    • 0029883680 scopus 로고    scopus 로고
    • A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer
    • Michalides R, Hageman P, Vantinteren H, Houben L, Wientjens E, Klompmaker R, and Peterse J (1996). A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer. Br J Cancer 73, 728-734.
    • (1996) Br J Cancer , vol.73 , pp. 728-734
    • Michalides, R.1    Hageman, P.2    Vantinteren, H.3    Houben, L.4    Wientjens, E.5    Klompmaker, R.6    Peterse, J.7
  • 50
    • 0030947356 scopus 로고    scopus 로고
    • High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers
    • Fredersdorf S, Burns J, Milne AM, Packham G, Fallis L, Gillett CE, Royds JA, Peston D, Hall PA, Hanby AM, et al. (1997). High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci USA 94, 6380-6385.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6380-6385
    • Fredersdorf, S.1    Burns, J.2    Milne, A.M.3    Packham, G.4    Fallis, L.5    Gillett, C.E.6    Royds, J.A.7    Peston, D.8    Hall, P.A.9    Hanby, A.M.10
  • 51
    • 0037063165 scopus 로고    scopus 로고
    • The cyclin D1 high and cyclin e high subgroups of breast cancer: Separate pathways in tumorigenesis based on pattern of genetic aberrations and inactivation of the pRb node
    • Lodén M, Stighall M, Nielsen NH, Roos G, Emdin SO, Östlund H, and Landberg G (2002). The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorigenesis based on pattern of genetic aberrations and inactivation of the pRb node. Oncogene 21, 4680-4690.
    • (2002) Oncogene , vol.21 , pp. 4680-4690
    • Lodén, M.1    Stighall, M.2    Nielsen, N.H.3    Roos, G.4    Emdin, S.O.5    Östlund, H.6    Landberg, G.7
  • 52
    • 0027026752 scopus 로고
    • The role of the retinoblastoma gene in breast cancer development
    • Fung YK and T'Ang A (1992). The role of the retinoblastoma gene in breast cancer development. Cancer Treat Res 61, 59-68.
    • (1992) Cancer Treat Res , vol.61 , pp. 59-68
    • Fung, Y.K.1    T'Ang, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.