메뉴 건너뛰기




Volumn 82, Issue 3, 2000, Pages 666-674

ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity an human mammary epithelial cells

Author keywords

ERBB 2; Human breast cancer; Human mammary epithelial cells; Invasion; P13' kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CELL SURFACE PROTEIN; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR;

EID: 0000446084     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.1999.0979     Document Type: Article
Times cited : (91)

References (53)
  • 1
    • 0021979244 scopus 로고
    • The interactions of plasma fibronectin with fibroblastic cells in suspension
    • Akiyama SK and Yamada KM (1985) The interactions of plasma fibronectin with fibroblastic cells in suspension. J Biol Chem 260: 4492-4500
    • (1985) J Biol Chem , vol.260 , pp. 4492-4500
    • Akiyama, S.K.1    Yamada, K.M.2
  • 2
    • 0030795612 scopus 로고    scopus 로고
    • The erbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligan-receptor interactions
    • Alroy I and Yarden Y (1997) The erbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligan-receptor interactions. FEBS Lett 410: 83-86
    • (1997) FEBS Lett , vol.410 , pp. 83-86
    • Alroy, I.1    Yarden, Y.2
  • 4
    • 0027971378 scopus 로고
    • The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell adhesive function
    • Aota S, Nomizu M and Yamada KM (1994) The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell adhesive function. J Biol Chem 269: 24756-24761
    • (1994) J Biol Chem , vol.269 , pp. 24756-24761
    • Aota, S.1    Nomizu, M.2    Yamada, K.M.3
  • 5
    • 0029873045 scopus 로고    scopus 로고
    • Association of phosphatidylinositol 3-kinase, via the SH2 domains of p85, with focal adhesion kinase in polymoma middle t-transformed fibroblasts
    • Bachelot C, Ramesh L, Parsons T and Cantley LC (1996) Association of phosphatidylinositol 3-kinase, via the SH2 domains of p85, with focal adhesion kinase in polymoma middle t-transformed fibroblasts. Biochimica et Biophisica Acta 1311: 45-52
    • (1996) Biochimica et Biophisica Acta , vol.1311 , pp. 45-52
    • Bachelot, C.1    Ramesh, L.2    Parsons, T.3    Cantley, L.C.4
  • 6
    • 0024512996 scopus 로고
    • Distinctive traits of normal and tumor derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types
    • Band V and Sager R (1989) Distinctive traits of normal and tumor derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types. Proc Natl Acad Sci USA 86: 1249-1253
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1249-1253
    • Band, V.1    Sager, R.2
  • 8
    • 0028229715 scopus 로고
    • A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway
    • Benlevy R, Paterson HF, Marshall CJ and Yarden Y (1994) A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway. EMBO J 13: 3302-3311
    • (1994) EMBO J , vol.13 , pp. 3302-3311
    • Benlevy, R.1    Paterson, H.F.2    Marshall, C.J.3    Yarden, Y.4
  • 9
    • 0023857935 scopus 로고
    • Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading
    • Berger MS, Locher GW, Saurer S, Gullick WJ, Waterfield MD, Groner B and Hynes NE (1988) Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading. Cancer Res 48: 1238-1243
    • (1988) Cancer Res , vol.48 , pp. 1238-1243
    • Berger, M.S.1    Locher, G.W.2    Saurer, S.3    Gullick, W.J.4    Waterfield, M.D.5    Groner, B.6    Hynes, N.E.7
  • 11
    • 0023939621 scopus 로고
    • In vivo amplification and rearrangement of c-myc oncogene in human breast tumors
    • Bonilla M, Ramirez M, Lopez-Cueto J and Gariglio P (1988) In vivo amplification and rearrangement of c-myc oncogene in human breast tumors. J Natl Cancer Inst 80: 665-671
    • (1988) J Natl Cancer Inst , vol.80 , pp. 665-671
    • Bonilla, M.1    Ramirez, M.2    Lopez-Cueto, J.3    Gariglio, P.4
  • 12
    • 0026747669 scopus 로고
    • c-myc amplification is an independent prognostic factor in postmenopausal breast cancer
    • Borg A, Baldetorp B, Ferno M, Olsson H and Sigurdsson H (1992) c-myc amplification is an independent prognostic factor in postmenopausal breast cancer. Int J Cancer 51: 687-691
    • (1992) Int J Cancer , vol.51 , pp. 687-691
    • Borg, A.1    Baldetorp, B.2    Ferno, M.3    Olsson, H.4    Sigurdsson, H.5
  • 13
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Analytical Biochemistry 72: 248-254
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 14
    • 0023723148 scopus 로고
    • Cryptic chemotactic activity of fibronectin for human monocytes resides in the 120 kDa fibroblastic cell binding fragment
    • Clark RAF, Wikner NE, Doherty DE and Norris DA (1988) Cryptic chemotactic activity of fibronectin for human monocytes resides in the 120 kDa fibroblastic cell binding fragment. J Biol Chem 263: 1215-12123
    • (1988) J Biol Chem , vol.263 , pp. 1215-12123
    • Clark, R.A.F.1    Wikner, N.E.2    Doherty, D.E.3    Norris, D.A.4
  • 16
    • 0025328284 scopus 로고
    • The carboxy-terminal domains of erbB-2 and epidermal growth factor receptor exert different regulatory effects on intrinsic receptor tyrosine kinase function and transforming activity
    • DiFiore PP, Segatto O, Leonardo F, Fazioli F, Pierce JH and Aaronson SA (1990a) The carboxy-terminal domains of erbB-2 and epidermal growth factor receptor exert different regulatory effects on intrinsic receptor tyrosine kinase function and transforming activity. Mol Cell Biol 10: 2749-2756
    • (1990) Mol Cell Biol , vol.10 , pp. 2749-2756
    • DiFiore, P.P.1    Segatto, O.2    Leonardo, F.3    Fazioli, F.4    Pierce, J.H.5    Aaronson, S.A.6
  • 17
    • 0025320158 scopus 로고
    • EGF receptor and erbB-2 tyrosine kinase domains confer cell specificity for mitogenic signaling
    • DiFiore PP, Segatto O, Taylor WG, Aaronson SA and Pierce JH (1990b) EGF receptor and erbB-2 tyrosine kinase domains confer cell specificity for mitogenic signaling. Science 248: 79-83
    • (1990) Science , vol.248 , pp. 79-83
    • DiFiore, P.P.1    Segatto, O.2    Taylor, W.G.3    Aaronson, S.A.4    Pierce, J.H.5
  • 19
    • 0028120910 scopus 로고
    • Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes erbB-3 signaling from that of other erbB EGFr family members
    • Fedi P, Pierce JH, Difiore PP and Kraus MH (1994) Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes erbB-3 signaling from that of other erbB EGFr family members. Mol Cell Biol 14: 492-500
    • (1994) Mol Cell Biol , vol.14 , pp. 492-500
    • Fedi, P.1    Pierce, J.H.2    Difiore, P.P.3    Kraus, M.H.4
  • 20
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclinD1 in breast cancer detected by immunohistochemical staining
    • Gillet CV, Fantl R, Smith C, Fisher J, Bartek C, Dickson D, Barnes and Peters G (1994) Amplification and overexpression of cyclinD1 in breast cancer detected by immunohistochemical staining. Cancer Res 54: 1812-1817
    • (1994) Cancer Res , vol.54 , pp. 1812-1817
    • Gillet, C.V.1    Fantl, R.2    Smith, C.3    Fisher, J.4    Bartek, C.5    Dickson, D.6    Peters, G.7
  • 21
    • 0026605281 scopus 로고
    • Degradation of fibronectin and vitronectin in chronic wound fluid: Analysis by cell blotting, immunoblotting, and cell adhesion assays
    • Grinnell F, Ho CH and Wysocki AJ (1992) Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays. J Invest Derm 98: 410-416
    • (1992) J Invest Derm , vol.98 , pp. 410-416
    • Grinnell, F.1    Ho, C.H.2    Wysocki, A.J.3
  • 22
    • 0030772959 scopus 로고    scopus 로고
    • Role of focal adhesion kinase in integrin signaling
    • Guan JL (1997) Role of focal adhesion kinase in integrin signaling. Int J Biochem, and Cell Biol 29: 1085-1096
    • (1997) Int J Biochem, and Cell Biol , vol.29 , pp. 1085-1096
    • Guan, J.L.1
  • 23
    • 0024593236 scopus 로고
    • Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: Prognostic significance
    • Guerin M, Gabillot M, Mathieu MC, Travagli JP, Spielmann NA and Riou G (1989) Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance. Int J Cancer 43: 201-208
    • (1989) Int J Cancer , vol.43 , pp. 201-208
    • Guerin, M.1    Gabillot, M.2    Mathieu, M.C.3    Travagli, J.P.4    Spielmann, N.A.5    Riou, G.6
  • 24
    • 0031887251 scopus 로고    scopus 로고
    • Novel mechanisms of E2F induction by BK virus large T antigen: Requirement of both the pRb binding and J domains
    • Harris KF, Christensen JB, Radany EH and Imperiale MJ (1998) Novel mechanisms of E2F induction by BK virus large T antigen: requirement of both the pRb binding and J domains. Mol Cell Biol 18: 1746-1756
    • (1998) Mol Cell Biol , vol.18 , pp. 1746-1756
    • Harris, K.F.1    Christensen, J.B.2    Radany, E.H.3    Imperiale, M.J.4
  • 25
    • 0020010505 scopus 로고
    • Fibronectin: Purification, immunochemical properties, and biological activities
    • Hayman EG, Pierschbacher M and Engvall E (1982) Fibronectin: purification, immunochemical properties, and biological activities. Meth Enzymol 82: 803-831
    • (1982) Meth Enzymol , vol.82 , pp. 803-831
    • Hayman, E.G.1    Pierschbacher, M.2    Engvall, E.3
  • 26
    • 0023430930 scopus 로고
    • Increased expression of the putative growth factor receptor p185Her2 causes transformation and tumorigenesis of NIH3T3 cells
    • Hudziak RM, Schlessinger J and Ullrich A (1987) Increased expression of the putative growth factor receptor p185Her2 causes transformation and tumorigenesis of NIH3T3 cells. Proc Natl Acad Sci USA 84: 7159-7163
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7159-7163
    • Hudziak, R.M.1    Schlessinger, J.2    Ullrich, A.3
  • 27
    • 0028987190 scopus 로고
    • Cooperative signaling by α5β1 and α4β1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin
    • Huhtala P, Humphries MJ, McCarthy JB, Tremble PM, Werb Z and Damsky CH (1995) Cooperative signaling by α5β1 and α4β1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J Cell Biol 129: 867-879
    • (1995) J Cell Biol , vol.129 , pp. 867-879
    • Huhtala, P.1    Humphries, M.J.2    McCarthy, J.B.3    Tremble, P.M.4    Werb, Z.5    Damsky, C.H.6
  • 28
    • 0031044781 scopus 로고    scopus 로고
    • Focal adhesion kinase at the crossroads of signal transduction
    • Ilic D, Damsky CH and Yamamoto T (1997) Focal adhesion kinase at the crossroads of signal transduction. J Cell Science 110: 401-407
    • (1997) J Cell Science , vol.110 , pp. 401-407
    • Ilic, D.1    Damsky, C.H.2    Yamamoto, T.3
  • 31
    • 0023301170 scopus 로고
    • Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms
    • Kraus MH, Popescu NC, Amsbaugh SC and King CR (1987) Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms. EMBO J 6: 605-610
    • (1987) EMBO J , vol.6 , pp. 605-610
    • Kraus, M.H.1    Popescu, N.C.2    Amsbaugh, S.C.3    King, C.R.4
  • 32
    • 0028839475 scopus 로고
    • Invasion of selectively permeable sea urchin embryo basement membranes by metastatic tumor cells, but not by their normal counterparts
    • Livant DL, Linn S, Markwart S and Shuster J (1995) Invasion of selectively permeable sea urchin embryo basement membranes by metastatic tumor cells, but not by their normal counterparts. Cancer Res 55: 5085-5093
    • (1995) Cancer Res , vol.55 , pp. 5085-5093
    • Livant, D.L.1    Linn, S.2    Markwart, S.3    Shuster, J.4
  • 33
    • 0025687686 scopus 로고
    • The normal erbB-2 product is a atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand
    • Lonardo F, DiMarco E, King CR, Pierce JH, Segatto O, Aaronson SA and DiFiori PP (1990) The normal erbB-2 product is a atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand. New Biol 2: 992-1003
    • (1990) New Biol , vol.2 , pp. 992-1003
    • Lonardo, F.1    DiMarco, E.2    King, C.R.3    Pierce, J.H.4    Segatto, O.5    Aaronson, S.A.6    DiFiori, P.P.7
  • 34
    • 0026696081 scopus 로고
    • Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues
    • Luqmani YA, Graham M and Coombes RC (1992) Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues. Br J Cancer 66: 273-280
    • (1992) Br J Cancer , vol.66 , pp. 273-280
    • Luqmani, Y.A.1    Graham, M.2    Coombes, R.C.3
  • 35
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor. PTEN/MMACI, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T and Dixon JE (1998) The tumor suppressor. PTEN/MMACI, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273: 13375-13378
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 36
    • 0028796895 scopus 로고
    • NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells
    • Marte BM, Grausporta D, Jeschke M, Fabbro D, Hynes NE and Taverna D (1995) NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells. Oncogene 10: 167-175
    • (1995) Oncogene , vol.10 , pp. 167-175
    • Marte, B.M.1    Grausporta, D.2    Jeschke, M.3    Fabbro, D.4    Hynes, N.E.5    Taverna, D.6
  • 39
    • 0019423313 scopus 로고
    • Induction of fibroblast chemotaxis by fibronectin: Localization of the chemotactic region to a 140,000 molecular weight nongelatin binding fragment
    • Postlethwaite AE, Keski-Oja J, Balian G and Kang A (1981) Induction of fibroblast chemotaxis by fibronectin: localization of the chemotactic region to a 140,000 molecular weight nongelatin binding fragment. J Exp Med 153: 494-499
    • (1981) J Exp Med , vol.153 , pp. 494-499
    • Postlethwaite, A.E.1    Keski-Oja, J.2    Balian, G.3    Kang, A.4
  • 40
    • 0029929513 scopus 로고    scopus 로고
    • Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine phosphorylated erbB-2
    • Ram TG, Dilts CA, Dziubinski ML, Pierce LJ and Ethier SP (1996) Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine phosphorylated erbB-2. Mol Carcinogen 15: 227-238
    • (1996) Mol Carcinogen , vol.15 , pp. 227-238
    • Ram, T.G.1    Dilts, C.A.2    Dziubinski, M.L.3    Pierce, L.J.4    Ethier, S.P.5
  • 41
    • 0029824114 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase recruitment by p185 (erbB-2) and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification
    • Ram TG and Ethier SP (1996) Phosphatidylinositol 3-kinase recruitment by p185 (erbB-2) and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification. Cell Growth Differ 7: 551-561
    • (1996) Cell Growth Differ , vol.7 , pp. 551-561
    • Ram, T.G.1    Ethier, S.P.2
  • 42
    • 0028927693 scopus 로고
    • Expression of cellular adhesion molecules on human prostate tumor cell lines
    • Roklin OW and Cohen MB (1995) Expression of cellular adhesion molecules on human prostate tumor cell lines. Prostate 26: 205-212
    • (1995) Prostate , vol.26 , pp. 205-212
    • Roklin, O.W.1    Cohen, M.B.2
  • 45
    • 0030962953 scopus 로고    scopus 로고
    • A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines
    • Sen S, Zhou HY and White RA (1997) A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines. Oncogene 14: 2195-2200
    • (1997) Oncogene , vol.14 , pp. 2195-2200
    • Sen, S.1    Zhou, H.Y.2    White, R.A.3
  • 47
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A and McGuire WL (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 48
    • 0028302018 scopus 로고
    • ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
    • Soltoff SP, Carraway KL, Prigent SA, Gullick WG and Cantley LC (1994) ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol 14: 3550-3558
    • (1994) Mol Cell Biol , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway, K.L.2    Prigent, S.A.3    Gullick, W.G.4    Cantley, L.C.5
  • 49
    • 0033556443 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: Differnential involvement of focal adhesion kinase and p130Cas
    • Tamura M, Gu J, Takino T and Yamada KM (1999) Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differnential involvement of focal adhesion kinase and p130Cas. Cancer Res 59: 442-449
    • (1999) Cancer Res , vol.59 , pp. 442-449
    • Tamura, M.1    Gu, J.2    Takino, T.3    Yamada, K.M.4
  • 50
    • 0027207207 scopus 로고
    • Relationship of c-myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis
    • Watson PH, Safneck JR, Le K, Dubik D and Shiu RPC (1993) Relationship of c-myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis. J Natl Cancer Inst 85: 902-907
    • (1993) J Natl Cancer Inst , vol.85 , pp. 902-907
    • Watson, P.H.1    Safneck, J.R.2    Le, K.3    Dubik, D.4    Shiu, R.P.C.5
  • 51
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C and Bissell MJ (1997) Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 137: 231-245
    • (1997) J Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3    Larabell, C.A.4    Briand, P.5    Damsky, C.6    Bissell, M.J.7
  • 52
    • 0027245106 scopus 로고
    • Characterization of integrin subunits, cellular adhesion and tumorigenicity of four human prostate cell lines
    • Witkowski CM, Rabinovitz I, Nagle RB, Affinito KD and Cress AE (1993) Characterization of integrin subunits, cellular adhesion and tumorigenicity of four human prostate cell lines. Cancer Res Clin Oncol 119: 637-644
    • (1993) Cancer Res Clin Oncol , vol.119 , pp. 637-644
    • Witkowski, C.M.1    Rabinovitz, I.2    Nagle, R.B.3    Affinito, K.D.4    Cress, A.E.5
  • 53
    • 0033304746 scopus 로고    scopus 로고
    • ErbB-2 overexpression in human mammary epithelial cells confers growth factor independence
    • Woods Ignatoski KM, LaPointe AJ, Radany EH and Ethier SP (1999) ErbB-2 overexpression in human mammary epithelial cells confers growth factor independence. Endocrinology 140:3615-3622
    • (1999) Endocrinology , vol.140 , pp. 3615-3622
    • Woods Ignatoski, K.M.1    LaPointe, A.J.2    Radany, E.H.3    Ethier, S.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.