메뉴 건너뛰기




Volumn 7, Issue 8, 2005, Pages 761-770

Differential regulation of cyclooxygenase-2 in nontransformed and Ras-transformed intestinal epithelial cells

Author keywords

COX 2; Epidermal growth factor; Ras; RhoA; Transforming growth factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; RAS PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; PROSTAGLANDIN E2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 33644698083     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.04652     Document Type: Article
Times cited : (8)

References (52)
  • 1
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • FitzGerald G and Patrono C (2001). The coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 345, 433-442.
    • (2001) N Engl J Med , vol.345 , pp. 433-442
    • FitzGerald, G.1    Patrono, C.2
  • 5
    • 0041630722 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and colorectal cancer
    • DuBois RN (2003). Cyclooxygenase-2 and colorectal cancer. Prog Exp Tumor Res 37, 124-137.
    • (2003) Prog Exp Tumor Res , vol.37 , pp. 124-137
    • DuBois, R.N.1
  • 7
    • 0034105197 scopus 로고    scopus 로고
    • Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of APC mutant Min mouse adenomas, and selective toxicity against APC mutant embryos
    • Jacoby RF, Cole CE, Tutsch K, Newton MA, Kelloff G, Hawk ET, and Lubet RA (2000). Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of APC mutant Min mouse adenomas, and selective toxicity against APC mutant embryos. Cancer Res 60, 1864-1870.
    • (2000) Cancer Res , vol.60 , pp. 1864-1870
    • Jacoby, R.F.1    Cole, C.E.2    Tutsch, K.3    Newton, M.A.4    Kelloff, G.5    Hawk, E.T.6    Lubet, R.A.7
  • 8
    • 0028344102 scopus 로고
    • Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor alpha and phorbol ester
    • DuBois RN, Awad J, Morrow JD, Roberts LJ, and Bishop PR (1994). Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor alpha and phorbol ester. J Clin Invest 93, 493-498.
    • (1994) J Clin Invest , vol.93 , pp. 493-498
    • DuBois, R.N.1    Awad, J.2    Morrow, J.D.3    Roberts, L.J.4    Bishop, P.R.5
  • 11
    • 0030967310 scopus 로고    scopus 로고
    • Cyclooxygenase-2 induction and transforming growth factor beta growth inhibition in rat intestinal epithelial cells
    • Sheng H, Shao J, Hooten EB, Tsujii M, DuBois RN, and Beauchamp RD (1997). Cyclooxygenase-2 induction and transforming growth factor beta growth inhibition in rat intestinal epithelial cells. Cell Growth Differ 8, 463-470.
    • (1997) Cell Growth Differ , vol.8 , pp. 463-470
    • Sheng, H.1    Shao, J.2    Hooten, E.B.3    Tsujii, M.4    DuBois, R.N.5    Beauchamp, R.D.6
  • 12
    • 0032787558 scopus 로고    scopus 로고
    • HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: Activation mediated through the ERK2 signaling pathway
    • Jones MK, Sasaki E, Halter F, Pai R, Nakamura T, Arakawa T, Kuroki T, and Tarnawski AS (1999). HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: activation mediated through the ERK2 signaling pathway. FASEB J 13, 2186-2194.
    • (1999) FASEB J , vol.13 , pp. 2186-2194
    • Jones, M.K.1    Sasaki, E.2    Halter, F.3    Pai, R.4    Nakamura, T.5    Arakawa, T.6    Kuroki, T.7    Tarnawski, A.S.8
  • 13
    • 0029950418 scopus 로고    scopus 로고
    • Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum
    • Xie W and Herschman HR (1996). Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J Biol Chem 271, 31742-31748.
    • (1996) J Biol Chem , vol.271 , pp. 31742-31748
    • Xie, W.1    Herschman, H.R.2
  • 14
    • 0032867341 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells
    • Matsuura H, Sakaue M, Subbaramaiah K, Kamitani H, Eling TE, Dannenberg AJ, Tanabe T, Inoue H, Arata J, and Jetten AM (1999). Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. J Biol Chem 274, 29138-29148.
    • (1999) J Biol Chem , vol.274 , pp. 29138-29148
    • Matsuura, H.1    Sakaue, M.2    Subbaramaiah, K.3    Kamitani, H.4    Eling, T.E.5    Dannenberg, A.J.6    Tanabe, T.7    Inoue, H.8    Arata, J.9    Jetten, A.M.10
  • 15
    • 0037073757 scopus 로고    scopus 로고
    • Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor
    • Guo YS, Cheng JZ, Jin GF, Gutkind JS, Hellmich MR, and Townsend CM Jr (2002). Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. J Biol Chem 277, 48755-48763.
    • (2002) J Biol Chem , vol.277 , pp. 48755-48763
    • Guo, Y.S.1    Cheng, J.Z.2    Jin, G.F.3    Gutkind, J.S.4    Hellmich, M.R.5    Townsend Jr., C.M.6
  • 16
    • 0032555484 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 by activated Ha-Ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
    • Sheng H, Williams CS, Shao J, Liang P, DuBois RN, and Beauchamp RD (1998). Induction of cyclooxygenase-2 by activated Ha-Ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J Biol Chem 273, 22120-22127.
    • (1998) J Biol Chem , vol.273 , pp. 22120-22127
    • Sheng, H.1    Williams, C.S.2    Shao, J.3    Liang, P.4    DuBois, R.N.5    Beauchamp, R.D.6
  • 17
    • 0034710802 scopus 로고    scopus 로고
    • Differential regulation of COX-2 transcription by Ras- and Rho-family of GTPases
    • Slice LL, Bui L, Mak C, and Walsh JH (2000). Differential regulation of COX-2 transcription by Ras- and Rho-family of GTPases. Biochem Biophys Res Commun 276, 406-410.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 406-410
    • Slice, L.L.1    Bui, L.2    Mak, C.3    Walsh, J.H.4
  • 19
    • 0035866755 scopus 로고    scopus 로고
    • K-ras-mediated increase in cyclooxygenase 2 mRNA stability involves activation of the protein kinase B1
    • Sheng H, Shao J, and DuBois RN (2001). K-ras-mediated increase in cyclooxygenase 2 mRNA stability involves activation of the protein kinase B1. Cancer Res 61, 2670-2675.
    • (2001) Cancer Res , vol.61 , pp. 2670-2675
    • Sheng, H.1    Shao, J.2    DuBois, R.N.3
  • 20
    • 0038446034 scopus 로고    scopus 로고
    • ROCK and nuclear factor kappaB-dependent activation of cyclooxygenase-2 by RHO GTPases: Effects on tumor growth and therapeutic consequences
    • Benitah SA, Valeron PF, and Lacal JC (2003). ROCK and nuclear factor kappaB-dependent activation of cyclooxygenase-2 by RHO GTPases: effects on tumor growth and therapeutic consequences. Mol Biol Cell 14, 3041-3054.
    • (2003) Mol Biol Cell , vol.14 , pp. 3041-3054
    • Benitah, S.A.1    Valeron, P.F.2    Lacal, J.C.3
  • 21
    • 0030880741 scopus 로고    scopus 로고
    • Increasing complexity of Ras signal transduction, involvement of Rho family proteins
    • Khosravi-Far R, Campbell S, Rossman KL, and Der CJ (1998). Increasing complexity of Ras signal transduction, involvement of Rho family proteins. Adv Cancer Res 72, 57-107.
    • (1998) Adv Cancer Res , vol.72 , pp. 57-107
    • Khosravi-Far, R.1    Campbell, S.2    Rossman, K.L.3    Der, C.J.4
  • 22
    • 0030762433 scopus 로고    scopus 로고
    • A Raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells
    • Gangarosa LM, Sizemore N, Graves-Deal R, Oldham SM, Der CJ, and Coffey RJ (1997). A Raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells. J Biol Chem 272, 18926-18931.
    • (1997) J Biol Chem , vol.272 , pp. 18926-18931
    • Gangarosa, L.M.1    Sizemore, N.2    Graves-Deal, R.3    Oldham, S.M.4    Der, C.J.5    Coffey, R.J.6
  • 23
    • 0026068693 scopus 로고
    • Characterization of the mouse transforming growth factor-beta 1 promoter and activation by the Ha-Ras oncogene
    • Geiser AG, Kim SJ, Roberts AB, and Sporn MB (1991). Characterization of the mouse transforming growth factor-beta 1 promoter and activation by the Ha-Ras oncogene. Mol Cell Biol 11, 84-92.
    • (1991) Mol Cell Biol , vol.11 , pp. 84-92
    • Geiser, A.G.1    Kim, S.J.2    Roberts, A.B.3    Sporn, M.B.4
  • 25
    • 0021868251 scopus 로고
    • Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells
    • Blay J and Brown KD (1985). Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells. J Cell Physiol 124, 107-112.
    • (1985) J Cell Physiol , vol.124 , pp. 107-112
    • Blay, J.1    Brown, K.D.2
  • 26
    • 0029959434 scopus 로고    scopus 로고
    • Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells
    • Oldham SM, Clark GJ, Gangarosa LM, Coffey JRJ, and Der CJ (1996). Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells. Proc Natl Acad Sci USA 93, 6924-6928.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6924-6928
    • Oldham, S.M.1    Clark, G.J.2    Gangarosa, L.M.3    Coffey, J.R.J.4    Der, C.J.5
  • 27
    • 0038737918 scopus 로고    scopus 로고
    • Growth inhibitory signalling by TGFbeta is blocked in Ras-transformed intestinal epithelial cells at a post-receptor locus
    • Jiang B, Zhang JS, Du J, Urrutia R, and Barnard J (2003). Growth inhibitory signalling by TGFbeta is blocked in Ras-transformed intestinal epithelial cells at a post-receptor locus. Cell Signal 15, 699-708.
    • (2003) Cell Signal , vol.15 , pp. 699-708
    • Jiang, B.1    Zhang, J.S.2    Du, J.3    Urrutia, R.4    Barnard, J.5
  • 28
    • 0021330444 scopus 로고
    • Differential effects of epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serumfree cultures of AKR-2B cells
    • Shipley GD, Childs CB, Volkenant ME, and Moses HL (1984). Differential effects of epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serumfree cultures of AKR-2B cells. Cancer Res 44, 710-716.
    • (1984) Cancer Res , vol.44 , pp. 710-716
    • Shipley, G.D.1    Childs, C.B.2    Volkenant, M.E.3    Moses, H.L.4
  • 29
    • 0034089871 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 enhances Ha-Ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA
    • Sheng HJS, Dixon D, Williams CS, Prescott SM, DuBois RN, and Beauchamp RD (2000). Transforming growth factor-beta1 enhances Ha-Ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. J Biol Chem 275, 6628-6635.
    • (2000) J Biol Chem , vol.275 , pp. 6628-6635
    • Sheng, H.J.S.1    Dixon, D.2    Williams, C.S.3    Prescott, S.M.4    DuBois, R.N.5    Beauchamp, R.D.6
  • 31
    • 0028940917 scopus 로고
    • Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6)
    • Polk DB, McCollum GW, and Carpenter G (1995). Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6). J Cell Physiol 162, 427-433.
    • (1995) J Cell Physiol , vol.162 , pp. 427-433
    • Polk, D.B.1    McCollum, G.W.2    Carpenter, G.3
  • 32
  • 33
    • 0031936080 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity
    • Polk DB (1998). Epidermal growth factor receptor-stimulated intestinal epithelial cell migration requires phospholipase C activity. Gastroenterology 114, 493-502.
    • (1998) Gastroenterology , vol.114 , pp. 493-502
    • Polk, D.B.1
  • 34
    • 0032502765 scopus 로고    scopus 로고
    • Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
    • Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, et al. (1998). Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 273, 8890-8896.
    • (1998) J Biol Chem , vol.273 , pp. 8890-8896
    • Eguchi, S.1    Numaguchi, K.2    Iwasaki, H.3    Matsumoto, T.4    Yamakawa, T.5    Utsunomiya, H.6    Motley, E.D.7    Kawakatsu, H.8    Owada, K.M.9    Hirata, Y.10
  • 35
    • 0030697807 scopus 로고    scopus 로고
    • PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner
    • Bos M, Mendelsohn J, Kim YM, Albanell J, Fry DW, and Baselga J (1997). PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner. Clin Cancer Res 3, 2099-2106.
    • (1997) Clin Cancer Res , vol.3 , pp. 2099-2106
    • Bos, M.1    Mendelsohn, J.2    Kim, Y.M.3    Albanell, J.4    Fry, D.W.5    Baselga, J.6
  • 37
    • 3543112696 scopus 로고    scopus 로고
    • Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta
    • Du J, Jiang B, Coffey RJ, and Barnard J (2004). Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta. Mol Cancer Res 2, 233-241.
    • (2004) Mol Cancer Res , vol.2 , pp. 233-241
    • Du, J.1    Jiang, B.2    Coffey, R.J.3    Barnard, J.4
  • 39
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M and DuBois RN (1995). Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83, 493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 43
    • 0042532210 scopus 로고    scopus 로고
    • Regulation of COX-2 expression in human cancers
    • Dixon DA (2003). Regulation of COX-2 expression in human cancers. Prog Exp Tumor Res 37, 52-71.
    • (2003) Prog Exp Tumor Res , vol.37 , pp. 52-71
    • Dixon, D.A.1
  • 44
    • 0032843987 scopus 로고    scopus 로고
    • Pharmacological inhibition of Ras-transformed epithelial cell growth is linked to down-regulation of epidermal growth factor-related peptides
    • Sizemore N, Cox AD, Barnard JA, Oldham SM, Reynolds ER, Der CJ, and Coffey RJ (1999). Pharmacological inhibition of Ras-transformed epithelial cell growth is linked to down-regulation of epidermal growth factor-related peptides. Gastroenterology 117, 567-576.
    • (1999) Gastroenterology , vol.117 , pp. 567-576
    • Sizemore, N.1    Cox, A.D.2    Barnard, J.A.3    Oldham, S.M.4    Reynolds, E.R.5    Der, C.J.6    Coffey, R.J.7
  • 45
    • 0028962318 scopus 로고
    • Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: Potential involvement of alternate epidermal growth factor receptor ligands
    • Dlugosz AA, Cheng C, Williams EK, Darwiche N, Dempsey PJ, Mann B, Dunn AR, Coffey RJ Jr, and Yuspa SH (1995). Autocrine transforming growth factor alpha is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands. Cancer Res 55, 1883-1893.
    • (1995) Cancer Res , vol.55 , pp. 1883-1893
    • Dlugosz, A.A.1    Cheng, C.2    Williams, E.K.3    Darwiche, N.4    Dempsey, P.J.5    Mann, B.6    Dunn, A.R.7    Coffey Jr., R.J.8    Yuspa, S.H.9
  • 48
    • 2642527955 scopus 로고    scopus 로고
    • Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation
    • Woo RA and Poon RYC (2004). Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation. Genes Dev 18, 1317-1330.
    • (2004) Genes Dev , vol.18 , pp. 1317-1330
    • Woo, R.A.1    Poon, R.Y.C.2
  • 49
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • Bishop AL and Hall A (2000). Rho GTPases and their effector proteins. Biochem J 348 (Part 2), 241-255.
    • (2000) Biochem J , vol.348 , Issue.2 PART , pp. 241-255
    • Bishop, A.L.1    Hall, A.2
  • 50
    • 6344231714 scopus 로고    scopus 로고
    • Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility
    • Wheeler AP and Ridley AJ (2004). Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res 301, 43-49.
    • (2004) Exp Cell Res , vol.301 , pp. 43-49
    • Wheeler, A.P.1    Ridley, A.J.2
  • 51
    • 0034955193 scopus 로고    scopus 로고
    • Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: Dissociation from tyrosine phosphorylation of p130(CAS)
    • Sinnett-Smith J, Lunn JA, Leopoldt D, and Rozengurt E (2001). Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS). Exp Cell Res 266, 292-302.
    • (2001) Exp Cell Res , vol.266 , pp. 292-302
    • Sinnett-Smith, J.1    Lunn, J.A.2    Leopoldt, D.3    Rozengurt, E.4
  • 52
    • 0034823910 scopus 로고    scopus 로고
    • Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia
    • Walsh SV, Hopkins AM, Chen J, Narumiya S, Parkos CA, and Nusrat A (2001). Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia. Gastroenterology 121, 566-579.
    • (2001) Gastroenterology , vol.121 , pp. 566-579
    • Walsh, S.V.1    Hopkins, A.M.2    Chen, J.3    Narumiya, S.4    Parkos, C.A.5    Nusrat, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.