Regulation of the human LAT gene by the Elf-1 transcription factor

BMC Molecular Biology

Volumn 7, Issue , 2006, Pages

  Finco, Timothy S ^a   Justice Healy, Geri E ^a   Patel, Shivani J ^a   Hamilton, Victoria E ^a  

^a AGNES SCOTT COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CELL PROTEIN; TRANSCRIPTION FACTOR ELF 1; TRANSCRIPTION FACTOR RUNX2; DNA; ELF1 PROTEIN, HUMAN; LAT PROTEIN, HUMAN; MEMBRANE PROTEIN; NUCLEAR PROTEIN; RECOMBINANT PROTEIN; RUNX1 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL TYPE; CONTROLLED STUDY; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; GENETIC TRANSFECTION; GENETICS; LEUKEMIA CELL LINE; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; PROTEIN BINDING;

ANIMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BASE SEQUENCE; BINDING SITES; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA; GENE EXPRESSION REGULATION; HUMANS; JURKAT CELLS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-ETS; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSFECTION;

EID: 33644609859     PISSN: 14712199     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2199-7-4     Document Type: Article

References (54)

1. Samelson LE: Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins. Annu Rev Immunol 2002, 20:371-394.
2. Horejsi V, Zhang W, Schraven B: Transmembrane adaptor proteins: Organizers of immunoreceptor signalling. Nat Rev Immunol 2004, 4:603-616.
3. Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE: LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998, 92:83-92.
4. Weber JR, Orstavik S, Torgersen KM, Danbolt NC, Berg SF, Ryan JC, Tasken K, Imboden JB, Vaage JT: Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells. J Exp Med 1998, 187:1157-1161.
5. Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A: LAT is required for TCR-mediated activation of PLCgammal and the ras pathway. Immunity 1998, 9:617-626.
6. Zhang W, Irvin BJ, Trible RP, Abraham RT, Samelson LE: Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient jurkat cell line. Int Immunal 1999, 11:943-950.
7. Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, Dejarnette JB, Trible RP, Grinberg A, Tsay HC, Jacobs HM, Kessler CM, Long EO, Love PE, Samelson LE: Essential role of LAT in T cell development. Immunity 1999, 10:323-332.
8. Pasquet JM, Gross B, Quek L, Asazuma N, Zhang W, Sommers CL, Schweighoffer E, Tybulewicz V, Judd B, Lee JR, Koretzky G, Love PE, Samelson LE, Watson SP: LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. Mol Cell Nat 1999, 19:8326-8334.
9. Jevremovic D, Billadeau DD, Schoon RA, Dick CJ, Irvin BJ, Zhang W, Samelson LE, Abraham RT, Leibson PJ: Cutting edge: A role for the adaptor protein LAT in human NK cell-mediated cyto-toxicity. J Immunol 1999, 162:2453-2456.
10. Saitoh S, Arudchandran R, Manetz TS, Zhang W, Sommers CL, Love PE, Rivera J, Samelson LE: LAT is essential for fc(epsilon)RI-mediated mast cell activation. Immunity 2000, 12:525-535.
11. Judd BA, Myung PS, Obergfell A, Myers EE, Cheng AM, Watson SP, Pear WS, Allman D, Shattil SJ, Koretzky GA: Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling. J Exp Med 2002, 195:705-717.
12. Klem J, Verrett PC, Kumar V, Schatzle JD: 2B4 is constitutively associated with linker for the activation of T cells in glycolipid-enriched microdomains: Properties required for 2B4 lytic function. J Immunol 2002, 169:55-62.
13. Su YW, Herzog S, Lotz M, Feldhahn N, Muschen M, Jumaa H: The molecular requirements for LAT-mediated differentiation and the role of LAT in limiting pre-B cell expansion. Eur J Immunol 2004, 34:3614-3622.
14. Su YW, Jumaa H: LAT links the pre-BCR to calcium signaling. Immunity 2003, 19:295-305.
15. Oya K, Wang J, Watanabe Y, Koga R, Watanabe T. Appearance of the LAT protein at an early stage of B-cell development and its possible role. Immunology 2003, 109:351-359.
16. Facchetti F, Chan JK, Zhang W, Tironi A, Chilosi M, Parolini S, Notarangelo LD, Samelson LE: Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: Evaluation in normal and pathological conditions. Am J Pothol 1999, 154:1037-1046.
17. Maruyama K, Sugano S: Oligo-capping: A simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleoticies. Gene 1994, 138:171-174.
18. Schaefer BC: Revolutions in rapid amplification of cDNA ends: New strategies for polymerase chain reaction cloning of full-length cDNA ends. Anal Biochem 1995, 227:255-273.
19. Smale ST, Kadonaga JT: The RNA polymerase II core promoter. Annu Rev Biochem 2003, 72:449-479.
20. Wingender E, Chen X, Fricke E, Geffers R, Hehl R, Liebich I, Krull M, Matys V, Michael H, Ohnhauser R, Pruss M, Schacherer F, Thiele S, Urbach S: The TRANSFAC system on gene expression regulation. Nucleic Acids Res 2001, 29:281-283.
21. Quandt K, Frech K, Karas H, Wingender E, Werner T: MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 1995, 23:4878-4884.
22. Sandelin A, Alkema W, Engstrom P, Wasserman WW, Lenhard B: JASPAR: An open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res 2004, 32:D91-4.
23. Sementchenko VI, Watson DK: Ets target genes: Past, present and future. Oncogene 2000, 19:6533-6548.
24. Graves BJ, Petersen JM: Specificity within the ets family of transcription factors. Adv Cancer Res 1998, 75:1-55.
25. Sharrocks AD: The ETS-domain transcription factor family. Nat Rev Mol Cell Biol 2001, 2:827-837.
26. Oikawa T, Yamada T: Molecular biology of the ets family of transcription factors. Gene 2003, 303:11-34.
27. Hollenhorst PC, Jones DA, Graves BJ: Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Res 2004, 32:5693-5702.
28. Bassuk AG, Barton KP, Anandappa RT, Lu MM, Leiden JM: Expression pattern of the ets-related transcription factor elf-I. Mol Med 1998, 4:392-401.
29. Davis JN, Roussel MF: Cloning and expression of the murine elf-1 cDNA. Gene 1996, 171:265-269.
30. Wheeler JC, Shigesada K, Gergen JP, Ito Y: Mechanisms of transcriptional regulation by runt domain proteins. Semin Cell Dev Biol 2000, 11:369-375.
31. de Bruijn MF, Speck NA: Core-binding factors in hematopoiesis and immune function. Oncogene 2004, 23:4238-4248.
32. Mao S, Frank RC, Zhang J, Miyazaki Y, Nimer SD: Functional and physical interactions between AML1 proteins and an ETS protein, MEF: Implications for the pathogenesis of t(8;21)-positive leukemias. Mol Cell Biol 1999, 19:3635-3644.
33. Erman B, Cortes M, Nikolajczyk BS, Speck NA, Sen R: ETS-core binding factor: A common composite motif in antigen receptor gene enhancers. Mol Cell Biol 1998, 18:1322-1330.
34. Wotton D, Ghysdael J, Wang S, Speck NA, Owen MJ: Cooperative binding of ets-1 and core binding factor to DNA. Mol Cell Biol 1994, 14:840-850.
35. Sun W, Graves BJ, Speck NA: Transactivation of the moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins. J Virol 1995, 69:4941-4949.
36. Gu TL, Goetz TL, Graves BJ, Speck NA: Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and ets-1, modulate DNA binding by CBFalpha2 (AML1). Mol Cell Biol 2000, 20:91-103.
37. Kim WY, Sieweke M, Ogawa E, Wee HJ, Englmeier U, Graf T, Ito Y: Mutual activation of ets-1 and AMIL1 DNA binding by direct interaction of their autoinhibitory domains. EMBO J 1999, 18:1609-1620.
38. Goetz TL, Gu TL, Speck NA, Graves BJ: Auto-inhibition of ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2. Mol Cell Biol 2000, 20:81-90.
39. Geng Y, Laslo P, Barton K, Wang CR: Transcriptional regulation of CDIDI by ets family transcription factors. J Immunol 2005, 175:1022-1029.
40. Sarafova S, Siu G: A potential role for elf-1 in CD4 promoter function. J Biol Chem 1999, 274:16126-16134.
41. Rellahan BL, Jensen JP, Howcroft TK, Singer DS, Bonvini E, Weissman AM: Elf-1 regulates basal expression from the T cell antigen receptor zeta-chain gene promoter. J Immunol 1998, 160:2794-2801.
42. Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B: Cis-acting sequences required for inducible interieukin-2 enhancer function bind a novel ets-related protein, elf-1. Mol Cell Biol 1992, 12:1043-1053.
43. Otto F, Lubbert M, Stock M: Upstream and downstream targets of RUNX proteins. J Cell Biochem 2003, 89:9-18.
44. Takahashi A, Satake M, Yamaguchi-Iwai Y, Bae SC, Lu J, Maruyama M, Zhang YW, Oka H, Arai N, Arai K: Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2. Blood 1995, 86:607-616.
45. Halle JP, Haus-Seuffert P, Woltering C, Stelzer G, Meisterernst M: A conserved tissue-specific structure at a human T-cell receptor beta-chain core promoter. Mol Cell Biol 1997, 17:4220-4229.
46. Uchida H, Zhang J, Nimer SD: AML1A and AML1B can transactivate the human IL-3 promoter. J Immunol 1997, 158:2251-2258.
47. Bae SC, Ogawa E, Maruyama M, Oka H, Satake M, Shigesada K, Jenkins NA, Gilbert DJ, Copeland NG, Ito Y: PESP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials. Mol Cell Biol 1994, 14:3242-3252.
48. Taniuchi I, Osato M, Egawa T, Sunshine MJ, Bae SC, Komori T, Ito Y, Littman DR. Differential requirements for runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 2002, 111:621-633.
49. Gunther CV, Graves BJ: Identification of ETS domain proteins in murine T lymphocytes that interact with the moloney murine leukemia virus enhancer. Mol Cell Biol 1994, 14:7569-7580.
50. Mayall TP, Sheridan PL, Montminy MB, Jones KA. Distinct roles for P-CREB and LEF-1 in TCR aloha enhancer assembly and activation on chromatin templates in vitro. Genes Dev 1997, 11:887-899.
51. Sato M, Morii E, Komori T, Kawahata H, Sugimoto M, Terai K, Shimizu H, Yasui T, Ogihara H, Yasui N, Ochi T, Kitamura Y, Ito Y, Nomura S: Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/ CBFAI and ETSI in the skeletal tissues. Oncogene 1998, 17:1517-1525.
52. Kamachi Y, Ogawa E, Asano M, Ishida S, Murakami Y, Satake M, Ito Y, Shigesada K: Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer. J Virol 1990, 64:4808-4819.
53. Cho JY, Akbarali Y, Zerbini LF, Gu X, Boltax J, Wang Y, Oettgen P, Zhang DE, Libermann TA: Isoforms of the ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. J Biol Chem 2004, 279:19512-19522.
54. Akbarali Y, Oettgen P, Boltax J, Libermann TA: ELF-1 interacts with and transactivates the IgH enhancer pi site. J Biol Chem 1996, 271:26007-26012.