Non-CpG cytosine methylation of p53 exon 5 in non-small cell lung carcinoma

Lung Cancer

Volumn 50, Issue 3, 2005, Pages 299-307

  Kouidou, Sofia ^a   Agidou, Tania ^a   Kyrkou, Athena ^a   Andreou, Alexandra ^a   Katopodi, Theodora ^a   Georgiou, Elisavet ^a   Krikelis, Dimitris ^a   Dimitriadou, Afroditi ^a   Spanos, Panagiotis ^a   Tsilikas, Christos ^b   Destouni, Hara ^b   Tzimagiorgis, Georgios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b THEAGENIO CANCER HOSPITAL   (Greece)

Author keywords

Exon 5; Lung carcinoma; MSP; Mutation; Non CpG methylation; p53

Indexed keywords

CYTOSINE DERIVATIVE; PROTEIN P53;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; DNA ISOLATION; GENE MUTATION; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INCIDENCE; LEUKOCYTE; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

BASE SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CPG ISLANDS; CYTOSINE; DATABASES, GENETIC; DNA METHYLATION; DNA, NEOPLASM; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION;

EID: 33644517218     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2005.06.012     Document Type: Article

References (37)

1. P.A. Jones, and S.B. Baylin The fundamental role of epigenetic events in cancer Nat Rev Genet 3 2002 415 428
2. S. Pradhan, and P.O. Esteve Mammalian DNA (cytosine-5) methyltransferases and their expression Clin Immunol 109 2003 6 16
3. A. Hermann, H. Gowher, and A. Jeltsch Biochemistry and biology of mammalian DNA methyltransferases Cell Mol Life Sci 61 2004 2571 2587
4. S. Pradhan, A. Bacolla, R.D. Wells, and R.J. Roberts Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation J Biol Chem 274 1999 33002 33010
5. B.H. Ramsahoye, D. Biniszkiewicz, F. Lyko, V. Clark, A.P. Bird, and R. Jaenisch Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a Proc Natl Acad Sci USA 97 2000 5237 5242
6. C.L. Hsieh In vivo activity of murine de novo methyltransferases Dnmt3a and Dnmt3b Mol Cell Biol 19 1999 8211 8218
7. I.G. Lin, L. Han, A. Taghva, L.E. O'Brien, and C.L. Hsieh Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro Mol Cell Biol 22 2002 704 723
8. J.Y. Fang, J.A. Mikovits, R. Bagni, C.L. Petrow-Sadowski, and F.W. Ruscetti Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation J Virol 75 2001 9753 9761
9. J.E. Dodge, B.H. Ramsahoye, Z.G. Wo, M. Okano, and E. Li De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation Gene 289 2002 41 48
10. A.R. Brooks, R.N. Harkins, P. Wang, H.S. Qian, P. Liu, and G.M. Rubanyi Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle J Gene Med 6 2004 395 404
11. G.P. Pfeifer p53 mutational spectra and the role of methylated CpG sequences Mutat Res 450 2000 155 166
12. A.I. Robles, S.P. Linke, and C.C. Harris The p53 network in lung carcinogenesis Oncogene 21 2002 6898 6907
13. S.P. Hussain, L.J. Hofseth, and C.C. Harris Tumor suppressor genes: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment Lung Cancer 34 Suppl. 2 2001 S7 S15
14. D.H. Lee, T.R. O'Connor, and G.P. Pfeifer Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG → TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells Nucleic Acids Res 30 2002 3566 3573
15. S. Tornaletti, and G.P. Pfeifer Complete and tissue-independent methylation of CpG sites in the p53 gene: implications for mutations in human cancers Oncogene 10 1995 1493 1499
16. T. Soussi, and C. Beroud Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides Hum Mutat 21 2003 192 200
17. K. Ory, Y. Legros, C. Auguin, and T. Soussi Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation EMBO J 13 1994 3496 3504
18. S.N. Rodin, A.S. Rodin, A. Juhasz, and G.P. Holmquist Cancerous hyper-mutagenesis in p53 genes is possibly associated with transcriptional bypass of DNA lesions Mutat Res 510 2002 153 168
19. T. Soussi, and C. Beroud Assessing TP53 status in human tumours to evaluate clinical outcome Nat Rev Cancer 1 2001 233 240
20. J.H. Yoon, L.E. Smith, Z. Feng, M. Tang, C.S. Lee, and G.P. Pfeifer Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers Cancer Res 61 2001 7110 7117
21. P. Cherpillod, and P.A. Amstad Benzo[a]pyrene-induced mutagenesis of p53 hot-spot codons 248 and 249 in human hepatocytes Mol Carcinog 13 1995 15 20
22. J. Sambrook, E. Fritsch, and F.T. Maniatis Molecular cloning. A laboratory manual 2nd ed. 1989 Cold Spring Harbor Laboratory Press New York, NY
23. J.G. Herman, A. Merlo, L. Mao, R.G. Lapidus, J.P. Issa, and N.E. Davidson Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers Cancer Res 55 1995 4525 4530
24. C.A. Eads, and P.W. Laird Combined bisulfite restriction analysis K.I. Mills B.H. Ramsahoye Methods in molecular biology, DNA methylation protocols vol. 200 2002 Humana Press Inc. Totowa, NJ 71 85
25. W.A. Palmisano, K.K. Divine, G. Saccomanno, F.D. Gilliland, S.B. Baylin, and J.G. Herman Predicting lung cancer by detecting aberrant promoter methylation in sputum Cancer Res 60 2000 5954 5958
26. G.E. Plum, Y.W. Park, S.F. Singleton, and P.B. Dervan Breslauer Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study Proc Natl Acad Sci USA 87 1990 9436 9440
27. A. Papa, B. Ma, S. Kouidou, Q. Tang, C. Hang, and A. Antoniadis Genetic characterization of the M RNA segment of Crimean Congo hemorrhagic fever virus strains, China Emerg Infect Dis 8 2002 50 53
28. E. Ballestar, and A.P. Wolffe Methyl-CpG-binding proteins Targeting specific gene repression Eur J Biochem 268 2001 1 6
29. M. Hisano, H. Ohta, Y. Nishimune, and M. Nozaki Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Actl7b, represses its expression in somatic cells Nucleic Acids Res 31 2003 4797 4804
30. B. McIver, S.K. Grebe, L. Wang, I.D. Hay, A. Yokomizo, and W. Liu FHIT and TSG101 in thyroid tumours: aberrant transcripts reflect rare abnormal RNA processing events of uncertain pathogenetic or clinical significance Clin Endocrinol (Oxf) 52 2000 749 757
31. C.Y. Castro, M.L. Ostrowski, R. Barrios, L.K. Green, H.H. Popper, and S. Powell Relationship between Epstein-Barr virus and lymphoepithelioma-like carcinoma of the lung: a clinicopathologic study of 6 cases and review of the literature Hum Pathol 32 2001 863 872
32. S. Badal, V. Badal, I.E. Calleja-Macias, M. Kalantari, L.S. Chuang, and B.F. Li The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation Virology 324 2004 483 492
33. J.P. Spano, M.A. Massiani, M. Bentata, O. Rixe, S. Friard, and P. Bossi Non associated with severe immunodeficiency. Is HIV involved in the pathogenesis of non-infectious pulmonary complications in infected patients? Curr HIV Res 1 2003 385 393
34. J.P. Spano, M.A. Massiani, M. Bentata, O. Rixe, S. Friard, and P. Bossi Lung cancer in patients with HIV Infection and review of the literature Med Oncol 21 2004 109 115
35. M. Burke, A. Furman, M. Hoffman, S. Marmor, A. Blum, and I. Yust Lung cancer in patients with HIV infection: is it AIDS-related? HIV Med 5 2004 110 114
36. M. Burke, A. Furman, M. Hoffman, S. Marmor, A. Blum, and I. Yust Molecular pathogenesis of malignant mesothelioma and its relationship to simian virus 40 Clin Lung Cancer 5 2003 177 181
37. K. Sakuma, J.M. Chong, M. Sudo, T. Ushiku, Y. Inoue, and J. Shibahara High-density methylation of p14ARF and p16INK4A in Epstein-Barr virus-associated gastric carcinoma Int J Cancer 112 2004 273 278