Induction of maturation and cytokine release of human dendritic cells by Helicobacter pylori

Infection and Immunity

Volumn 72, Issue 8, 2004, Pages 4416-4423

  Kranzer, Katharina ^a   Eckhardt, Alexander ^a   Aigner, Michael ^a   Knoll, Gertrud ^a   Deml, Ludwig ^a   Speth, Cornelia ^b   Lehn, Norbert ^a   Rehli, Michael ^a   Schneider Brachert, Wulf ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; CD83 ANTIGEN; CD86 ANTIGEN; CYTOKINE; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8;

ANTIGEN PRESENTING CELL; ARTICLE; CELL MATURATION; CHRONIC GASTRITIS; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ESCHERICHIA COLI; FLUORESCENCE ACTIVATED CELL SORTING; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNE SYSTEM; INFLAMMATION; NORMAL HUMAN; PEPTIC ULCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANTIGENS, CD; CELL DIFFERENTIATION; CYTOKINES; DENDRITIC CELLS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HLA-DR ANTIGENS; HUMANS; INTERLEUKINS; MONOCYTES; SEROTYPING; UP-REGULATION;

EID: 3342996934     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.8.4416-4423.2004     Document Type: Article

References (61)

1. Amieva, M. R., R. Vogelmann, A. Covacci, L. S. Tompkins, W. J. Nelson, and S. Falkow. 2003. Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 300:1430-1434.
2. Ando, T., G. I. Perez-Perez, K. Kusugami, M. Ohsuga, K. C. Bloch, and M. J. Blaser. 2000. Anti-CagA immunoglobulin G responses correlate with interleukin-8 induction in human gastric mucosal biopsy culture. Clin. Diagn. Lab. Immunol. 7:803-809.
3. Appelmelk, B. J., D. van, I., S. J. van Vliet, C. M. Vandenbroucke- Grauls, T. B. Geijtenbeek, and Y. van Kooyk. 2003. Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells. J. Immunol. 170:1635-1639.
4. Bamford, K. B., X. Fan, S. E. Crowe, J. F. Leary, W. K. Gourley, G. K. Luthra, E. G. Brooks, D. Y. Graham, V. E. Reyes, and P. B. Ernst. 1998. Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype. Gastroenterology 114:482-492.
5. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y. J. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18:767-811.
6. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 19:392:245-252.
7. - T cells to acquire regulatory cell function. Blood 101:5076-5083.
8. Covacci, A., J. L. Telford, G. Del Giudice, J. Parsonnet, and R. Rappuoli. 1999. Helicobacter pylori virulence and genetic geography. Science 284:1328-1333.
9. de Jonge, R., J. G. Kusters, M. S. Timmer, V. Gimmel, B. J. Appelmelk, S. Bereswill, A. H. van Vliet, S. G. Meuwissen, M. Kist, C. M. Vandenbroucke-Grauls, and E. J. Kuipers. 2001. The role of Helicobacter pylori virulence factors in interleukin production by monocytic cells. FEMS Microbiol. Lett. 196:235-238.
10. Dixon, G. L., P. J. Newton, B. M. Chain, D. Katz, S. R. Andersen, S. Wong, P. van der Ley, N. Klein, and R. E. Callard. 2001. Dendritic cell activation and cytokine production induced by group B Neisseria meningitidis: interleukin-12 production depends on lipopolysaccharide expression in intact bacteria. Infect. Immun. 69:4351-4357.
11. Gebert, B., W. Fischer, E. Weiss, R. Hoffmann, and R. Haas. 2003. Helicobacter pylori vacuolating cytotoxin inhibits T. lymphocyte activation. Science 301:1099-1102.
12. Groux, H. 2003. Type 1 T-regulatory cells: their role in the control of immune responses. Transplantation 75:8S-12S.
13. Guermonprez, P., J. Valladeau, L. Zitvogel, C. Thery, and S. Amigorena. 2002. Antigen presentation and T-cell stimulation by dendritic cells. Annu. Rev. Immunol. 20:621-667.
14. Guiney, D. G., P. Hasegawa, and S. P. Cole. 2003. Helicobacter pylori preferentially induces interleukin 12 (IL-12) rather than IL-6 or IL-10 in human dendritic cells. Infect. Immun. 71:4163-4166.
15. Higgins, S. C., E. C. Lavelle, C. McCann, B. Keogh, E. McNeela, P. Byrne, B. O'Gorman, A. Jarnicki, P. McGuirk, and K. H. Mills. 2003. Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology. J. Immunol. 171:3119-3127.
16. Hornung, V., S. Rothenfusser, S. Britsch, A. Krug, B. Jahrsdorfer, T. Giese, S. Endres, and G. Hartmann. 2002. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J. Immunol. 168:4531-4537.
17. Innocenti, M., A. M. Svennerholm, and M. Quiding-Jarbrink. 2001. Helicobacter pylori lipopolysaccharides preferentially induce CXC chemokine production in human monocytes. Infect. Immun. 69:3800-3808.
18. Ismail, S., M. B. Hampton, and J. I. Keenan. 2003. Helicobacter pylori outer membrane vesicles modulate proliferation and interleukin-8 production by gastric epithelial cells. Infect. Immun. 71:5670-5675.
19. Jiang, W., W. J. Swiggard, C. Heufler, M. Peng, A. Mirza, R. M. Steinman, and M. C. Nussenzweig. 1995. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375:151-155.
20. Jutel, M., M. Akdis, F. Budak, C. Aebischer-Casaulta, M. Wrzyszcz, K. Blaser, and C. A. Akdis. 2003. IL-10 and TGF-β cooperate in the regulatory T-cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur. J. Immunol. 33:1205-1214.
21. Kalinski, P., C. M. Hilkens, E. A. Wierenga, and M. L. Kapsenberg. 1999. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol. Today 20:561-567.
22. Kapsenberg, M. L., C. M. Hilkens, E. A. Wierenga, and P. Kalinski. 1999. The paradigm of type 1 and type 2 antigen-presenting cells. Implications for atopic allergy. Clin. Exp. Allergy 29(Suppl. 2):33-36.
23. Kawahara, T., Y. Kuwano, S. Teshima-Kondo, T. Kawai, T. Nikawa, K. Kishi, and K. Rokutan. 2001. Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection. J. Med. Investig. 48:190-197.
24. Knipp, U., S. Birkholz, W. Kaup, K. Mahnke, and W. Opferkuch. 1994. Suppression of human mononuclear cell response by Helicobacter pylori: effects on isolated monocytes and lymphocytes. FEMS Immunol. Med. Microbiol. 8:157-166.
25. Knipp, U., S. Birkholz, W. Kaup, and W. Opferkuch. 1993. Immune suppressive effects of Helicobacter pylori on human peripheral blood mononuclear cells. Med. Microbiol. Immunol. 182:63-76.
26. Knipp, U., S. Birkholz, W. Kaup, and W. Opferkuch. 1996. Partial characterization of a cell proliferation-inhibiting protein produced by Helicobacter pylori. Infect. Immun. 64:3491-3496.
27. Krause, S. W., M. Rehli, M. Kreutz, L. Schwarzfischer, J. D. Paulauskis, and R. Andreesen. 1996. Differential screening identifies genetic markers of monocyte to macrophage maturation. J. Leukoc. Biol. 60:540-545.
28. Langenkamp, A., M. Messi, A. Lanzavecchia, and F. Sallusto. 2000. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. Nat. Immunol. 1:311-316.
29. Li, M., D. F. Carpio, Y. Zheng, P. Bruzzo, V. Singh, F. Ouaaz, R. M. Medzhitov, and A. A. Beg. 2001. An essential role of the NF-κB/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J. Immunol. 166:7128-7135.
30. Lindholm, C., M. Quiding-Jarbrink, H. Lonroth, A. Hamlet, and A. M. Svennerholm. 1998. Local cytokine response in Helicobacter pylori-infected subjects. Infect. Immun. 66:5964-5971.
31. high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals. Infect. Immun. 71:1755-1762.
32. Luzza, F., T. Parrello, G. Monteleone, L. Sebkova, M. Romano, R. Zarrilli, M. Imeneo, and F. Pallone. 2000. Upregulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa. J. Immunol. 165:5332-5337.
33. Matsuno, K., T. Ezaki, S. Kudo, and Y. Uehara. 1996. A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph. J. Exp. Med. 183:1865-1878.
34. Means, T. K., F. Hayashi, K. D. Smith, A. Aderem, and A. D. Luster. 2003. The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells. J. Immunol. 170:5165-5175.
35. Meyer, F., K. T. Wilson, and S. P. James. 2000. Modulation of innate cytokine responses by products of Helicobacter pylori. Infect. Immun. 68:6265-6272.
36. Mohammadi, M., S. Czinn, R. Redline, and J. Nedrud. 1996. Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice. J. Immunol. 156:4729-4738.
37. Mohammadi, M., J. Nedrud, R. Redline, N. Lycke, and S. J. Czinn. 1997. Murine CD4 T-cell response to Helicobacter infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load. Gastroenterology 113:1848-1857.
38. Molinari, M., M. Salio, C. Galli, N. Norais, R. Rappuoli, A. Lanzavecchia, and C. Montecucco. 1998. Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA. J. Exp. Med. 187:135-140.
39. Nakachi, N., T. W. Klein, H. Friedman, and Y. Yamamoto. 2000. Helicobacter pylori infection of human gastric epithelial cells induces IL-8 and TNFα, but not TGFβ1 mRNA. FEMS Immunol. Med. Microbiol. 29:23-26.
40. Nigou, J., C. Zelle-Rieser, M. Gilleron, M. Thurnher, and G. Puzo. 2001. Mannosylated lipoarabinomannans inhibit IL-12 production by human dendritic cells: evidence for a negative signal delivered through the mannose receptor. J. Immunol. 166:7477-7485.
41. Owen, R. J., S. Sharp, A. J. Lawson, Z. Durrani, S. Rijpkema, and M. Kidd. 2003. Investigation of the biological relevance of Helicobacter pylori cagE locus diversity, presence of CagA tyrosine phosphorylation motifs and vacuolating cytotoxin genotype on IL-8 induction in gastric epithelial cells. FEMS Immunol. Med. Microbiol. 36:135-140.
42. Parsonnet, J., G. D. Friedman, N. Orentreich, and H. Vogelman. 1997. Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut 40:297-301.
43. Parsonnet, J., S. Hansen, L. Rodriguez, A. B. Gelb, R. A. Warnke, E. Jellum, N. Orentreich, J. H. Vogelman, and G. D. Friedman. 1994. Helicobacter pylori infection and gastric lymphoma. N. Engl. J. Med. 330:1267-1271.
44. Ramarao, N., S. D. Gray-Owen, S. Backert, and T. F. Meyer. 2000. Helicobacter pylori inhibits phagocytosis by professional phagocytes involving type IV secretion components. Mol. Microbiol. 37:1389-1404.
45. Rescigno, M., M. Urbano, B. Valzasina, M. Francolini, G. Rotta, R. Bonasio, F. Granucci, J. P. Kraehenbuhl, and P. Ricciardi-Castagnoli. 2001. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2:361-367.
46. Rissoan, M. C., V. Soumelis, N. Kadowaki, G. Grouard, F. Briere, M. R. de Waal, and Y. J. Liu. 1999. Reciprocal control of T helper cell and dendritic cell differentiation. Science 283:1183-1186.
47. Rocha, G. A., D. M. Queiroz, E. N. Mendes, A. J. Barbosa, G. F. Lima Junior, and C. A. Oliveira. 1991. Helicobacter pylori acute gastritis: histological, endoscopical, clinical, and therapeutic features. Am. J. Gastroenterol. 86:1592-1595.
48. Sallusto, F., M. Cella, C. Danieli, and A. Lanzavecchia. 1995. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182:389-400.
49. Scheinecker, C., R. McHugh, E. M. Shevach, and R. N. Germain. 2002. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 196:1079-1090.
50. Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2:151-161.
51. Smith, M. F., Jr., A. Mitchell, G. Li, S. Ding, A. M. Fitzmaurice, K. Ryan, S. Crowe, and J. B. Goldberg. 2003. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-κB activation and chemokine expression by epithelial cells. J. Biol. Chem. 278:32552-32560.
52. Smythies, L. E., K. B. Waites, J. R. Lindsey, P. R. Harris, P. Ghiara, and P. D. Smith. 2000. Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient mice. J. Immunol. 165:1022-1029.
53. Sobala, G. M., J. E. Crabtree, M. F. Dixon, C. J. Schorah, J. D. Taylor, B. J. Rathbone, R. V. Heatley, and A. T. Axon. 1991. Acute Helicobacterpylori infection: clinical features, local and systemic immune response, gastric mucosal histology, and gastric juice ascorbic acid concentrations. Gut 32:1415-1418.
54. Sommer, F., G. Faller, M. Rollinghoff, T. Kirchner, T. W. Mak, and M. Lohoff. 2001. Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected with Helicobacter pylori. Eur. J. Immunol. 31:396-402.
55. Sousa, C., P. D. Stahl, and J. M. Austyn. 1993. Phagocytosis of antigens by Langerhans cells in vitro. J. Exp. Med. 178:509-519.
56. Stassi, G., A. Arena, A. Speranza, D. Iannello, and P. Mastroeni. 2002. Different modulation by live or killed Helicobacter pylori on cytokine production from peripheral blood mononuclear cells. New Microbiol. 25:247-252.
57. Su, B., P. J. Ceponis, S. Lebel, H. Huynh, and P. M. Sherman. 2003. Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells. Infect. Immun. 71:3496-3502.
58. Verhasselt, V., C. Buelens, F. Willems, D. De Groote, N. Haeffner-Cavaillon, and M. Goldman. 1997. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J. Immunol. 158:2919-2925.
59. Voland, P., N. Hafsi, M. Zeitner, S. Laforsch, H. Wagner, and C. Prinz. 2003. Antigenic properties of HpaA and Omp18, two outer membrane proteins of Helicobacter pylori. Infect. Immun. 71:3837-3843.
60. Wang, J., E. G. Brooks, K. B. Bamford, T. L. Denning, J. Pappo, and P. B. Ernst. 2001. Negative selection of T cells by Helicobacter pylori as a model for bacterial strain selection by immune evasion. J. Immunol. 167:926-934.
61. + T-cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-β. J. Immunol. 163:3684-3691.