Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells

Infection and Immunity

Volumn 71, Issue 6, 2003, Pages 3496-3502

  Su, Bin ^a   Ceponis, Peter J M ^a   Lebel, Sylvie ^a   Huynh, Hien ^a   Sherman, Philip M ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MONOCLONAL ANTIBODY; RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; BACTERIUM ISOLATE; CHO CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; INFLAMMATION; INTESTINE EPITHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIGENS, CD14; CELL LINE; CHEMOKINES; CHO CELLS; CRICETINAE; GASTRIC MUCOSA; GLYCOSYLATION; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-8; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; RECEPTORS, CELL SURFACE; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; UP-REGULATION;

EID: 0038781687     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.6.3496-3502.2003     Document Type: Article

References (32)

1. Akira, S., K. Hoshino, and T. Kaisho. 2000. The role of Toll-like receptors and MyD88 in innate immune responses. J. Endotoxin Res. 6:383-387.
2. Blaser, M. J., and D. E. Berg. 2001, Helicobacter pylori genetic diversity and risk of human disease. J. Clin. Investig. 107:767-773.
3. Cario, E., D. Brown, M. McKee, K. Lynch-Devaney, G. Gerken, and D. K. Podolsky. 2002. Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium. Am. J. Pathol. 160:165-173.
4. Cario, E., and D. K. Podolsky. 2000. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect. Immun. 68:7010-7017.
5. Cario, E., I. M. Rosenberg, S. L Brandwein, P. L. Beck, H. C. Reinecker, and D. K. Podolsky. 2000. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J. Immunol. 164:966-972.
6. da Silva Correia, J., and R. J. Ulevitch. 2002. MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor. J. Biol. Chem. 277:1845-1854.
7. Day, A. S., N. L. Jones, J. T. Lynett, H. A. Jennings, C. A. Fallone, R. Beech, and P. M. Sherman. 2000. cagE is a virulence factor associated with Helicobacter pylori-induced duodenal ulceration in children. J. Infect. Dis. 181:1370-1375.
8. Dreskin, S. C., G. W. Thomas, S. N. Dale, and L. E. Heasley. 2001. Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells. J. Immunol. 166:5646-5653.
9. Dytoc, M., B. Gold, M. Louie, M. Huesca, L. Fedorko, S. Crowe, C. Lingwood, J. Brunton, and P. M. Sherman. 1993. Comparison of Helicobacter pylori and attaching-effacing Escherichia coli adhesion to eukaryotic cells. Infect. Immun. 61:448-456.
10. Evans, D. G., T. K. Karjalainen, D. J. Evans, Jr., D. Y. Graham, and C. H. Lee. 1993. Cloning, nucleotide sequence, and expression of a gene encoding an adhesin subunit protein of Helicobacter pylori. J. Bacteriol. 175:674-683.
11. Evans, D. J., Jr., and D. G. Evans. 2000. Helicobacter pylori adhesins: review and perspectives. Helicobacter 5:183-195.
12. Falk, P., K. A. Roth, T. Borén, T. U. Westblöm, J. I. Gordon, and S. Normark. 1993. An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium. Proc. Natl. Acad. Sci. USA 90:2035-2039.
13. Fan, X., H. Gunasena, Z. Cheng, R. Espejo, S. E. Crowe, P. B. Ernst, and V. E. Reyes. 2000. Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis. J. Immunol. 165:1918-1924.
14. Gold, B. D., M. Huesca, P. M. Sherman, and C. A. Lingwood. 1993. Helicobacter mustelae and Helicobacter pylori bind to common lipid receptors in vitro. Infect. Immun. 61:2632-2638.
15. Jiang, Q., S. Akashi, K. Miyake, and H. R. Petty. 2000. Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J. Immunol. 165:3541-3544.
16. Kamisago, S., M. Iwamori, T. Tal, K. Mitamura, Y. Yazaki, and K. Sugano. 1996. Role of sulfatides in adhesion of Helicobacter pylori to gastric cancer cells. Infect. Immun. 64:624-628.
17. Karlsson, H., C. Hessle, and A. Rudin. 2002. Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora. Infect. Immun. 70:6688-6696.
18. Kawahara, T., S. Teshima, A. Oka, T. Sugiyama, K. Kishi, and K. Rokutan. 2001. Type I Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells. Infect. Immun. 69:4382-4389.
19. Lien, E., T. J. Sellati, A. Yoshimura, T. H. Flo, G. Rawadi, R. W. Finberg, J. D. Carroll, T. Espevik, R. R. Ingalls, J. D. Radolf, and D. T. Golenbock. 1999. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J. Biol. Chem. 274:33419-33425.
20. Maeda, S., M. Akanuma, Y. Mitsuno, Y. Hirata, K. Ogura, H. Yoshida, Y. Shiratori, and M. Omata. 2001. Distinct mechanism of Helicobacter pylorimediated NF-kappa B activation between gastric cancer cells and monocytic cells. J. Biol. Chem. 276:44856-44864.
21. Maeda, S., H. Yoshida, K. Ogura, Y. Mitsuno, Y. Hirata, Y. Yamaji, M. Akanuma, Y. Shiratori, and M. Omata. 2000. H. pylori activates NF-κB through a signaling pathway involving IκB kinases, NF-κB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells. Gastroenterology 119:97-108.
22. Medvedev, A. E., P. Henneke, A. Schromm, E. Lien, R. Ingalls, M. J. Fenton, D. T. Golenbock, and S. N. Vogel. 2001. Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4. J. Immunol. 167:2257-2267.
23. Nakanishi, K., T. Yoshimoto, H. Tsutsui, and H. Okamura. 2001. Interleukin-18 regulates both Th1 and Th2 responses. Annu. Rev. Immunol. 19:423-474.
24. Opitz, B., N. W. Schroder, I. Spreitzer, K. S. Michelsen, C. J. Kirschning, W. Hallatschek, U. Zahringer, T. Hartung, U. B. Gobel, and R. R. Schumann. 2001. Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappa B translocation. J. Biol. Chem. 276:22041-22047.
25. Ronnett, G. V., and M. D. Lane. 1981. Post-translational glycosylation-induced activation of aglycoinsulin receptor accumulated during tunicamycin treatment. J. Biol. Chem. 256:4704-4707.
26. Sharma, S. A., M. K. Tummuru, G. G. Miller, and M. J. Blaser. 1995. Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro. Infect. Immun. 63:1681-1687.
27. Slomiany, B. L., J. Piotrowski, A. Samanta, K. VanHorn, V. L. Murty, and A. Slomiany. 1989. Campylobacter pylori colonization factor shows specificity for lactosylceramide sulfate and GM3 ganglioside. Biochem. Int. 19:929-936.
28. Su, B., P. M. Hellström, C. Rubio, J. Célik, M. Granström, and S. Normark. 1998. Type I Helicobacter pylori shows Lewis(b)-independent adherence to gastric cells requiring de novo protein synthesis in both host and bacteria. J. Infect. Dis. 178:1379-1390.
29. Su, B., S. Johansson, M. Fällman, M. Patarroyo, M. Granström, and S. Normark. 1999. Signal transduction-mediated adherence and entry of Helicobacter pylori into cultured cells. Gastroenterology 117:595-604.
30. Teneberg, S., I. Leonardsson, H. Karlsson, P.-A. Jovall, J. Angstrom, D. Danielsson, I. Manslund, A. Ljung, T. Wadstrom, and K.-A. Karlsson. 2002. Lactotetraosylceramide, a novel glycosphingolipid receptor for Helicobacter pylori, present in human gastric epithelium. J. Biol. Chem. 277:19709-19719.
31. Vasselon, T., and P. A. Detmers. 2002. Toll receptors: a central element in innate immune responses. Infect. Immun. 70:1033-1041.
32. Wang, J. E., A. Warris, E. A. Ellingsen, P. F. Jorgensen, T. H. Flo, T. Espevik, R. Solberg, P. E. Verweij, and A. O. Aasen. 2001. Involvement of CD14 and Toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect. Immun. 69:2402-2406.