The role of CD30 in the pathogenesis of haematopoietic malignancies

Current Opinion in Pharmacology

Volumn 4, Issue 4, 2004, Pages 355-359

  Al Shamkhani, Aymen ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD30 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR RECEPTOR;

ANAPLASTIC CARCINOMA; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL DEATH; CELL SURVIVAL; GENE OVEREXPRESSION; HEMATOPOIETIC SYSTEM TUMOR; HODGKIN DISEASE; LARGE CELL LYMPHOMA; LEUKEMOGENESIS; MALIGNANT NEOPLASTIC DISEASE; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 3342992713     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2004.02.007     Document Type: Review

References (46)

1. Durkop H. Latza U. Hummel M. Eitelbach F. Seed B. Stein H. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease Cell 68 1992 421-427
2. Falini B. Pileri S. Pizzolo G. Durkop H. Flenghi L. Stirpe F. Martelli M.F. Stein H. CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy Blood 85 1995 1-14
3. Matsumoto K. Terakawa M. Miura K. Fukuda S. Nakajima T. Saito H. Extremely rapid and intense induction of apoptosis in human eosinophils by anti-CD30 antibody treatment in vitro J Immunol 172 2004 2186-2193
4. Wahl A.F. Klussman K. Thompson J.D. Chen J.H. Francisco L.V. Risdon G. Chace D.F. Siegall C.B. Francisco J.A. The anti-CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease Cancer Res 62 2002 3736-3742
5. Borchmann P. Treml J.F. Hansen H. Gottstein C. Schnell R. Staak O. Zhang H.F. Davis T. Keler T. Diehl V. et al. The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma Blood 102 2003 3737-3742
6. Horie R .Ito K. Tatewaki M. Nagai M. Aizawa S. Higashihara M. Ishida T. Inoue J. Takizawa H. Watanabe T. A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages Blood 88 1996 2422-2432
7. Horie R. Gattei V. Ito K. Imajo-Ohmi S. Tange T. Miyauchi J. Pinto A. Degan M. De Iuliis A. Tassan Mazzocco F. et al. Frequent expression of the variant CD30 in human malignant myeloid and lymphoid neoplasms Am J Pathol 155 1999 2029-2041
8. Smith C.A. Gruss H.J. Davis T. Anderson D. Farrah T. Baker E. Sutherland G.R. Brannan C.I. Copeland N.G. Jenkins N.A. et al. CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF Cell 73 1993 1349-1360
9. Staudt L.M. The molecular and cellular origins of Hodgkin's disease J Exp Med 191 2000 207-212
10. Hinz M. Lemke P. Anagnostopoulos I. Hacker C. Krappmann D. Mathas S. Dorken B. Zenke M. Stein H. Scheidereit C. Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity J Exp Med 196 2002 605-617
11. Pinto A. Aldinucci D. Gloghini A. Zagonel V. Degan M. Improta S. Juzbasic S. Todesco M. Perin V. Gattei V. et al. Human eosinophils express functional CD30 ligand and stimulate proliferation of a Hodgkin's disease cell line Blood 88 1996 3299-3305
12. Molin D. Fischer M. Xiang Z. Larsson U. Harvima I. Venge P. Nilsson K. Sundstrom C. Enblad G. Nilsson G. Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease Br J Haematol 114 2001 616-623
13. Hsu P.L. Hsu S.M. Autocrine growth regulation of CD30 ligand in CD30-expressing Reed-Sternberg cells: distinction between Hodgkin's disease and anaplastic large cell lymphoma Lab Invest 80 2000 1111-1119
14. Gattei V. Degan M. Gloghini A. De Iuliis A. Improta S. Rossi F.M. Aldinucci D. Perin V. Serraino D. Babare R. et al. CD30 ligand is frequently expressed in human hematopoietic malignancies of myeloid and lymphoid origin Blood 89 1997 2048-2059
15. Cerutti A. Kim E.C. Shah S. Schattner E.J. Zan H. Schaffer A. Casali P. Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells Nat Immunol 2 2001 150-156
16. Croager E.J. Gout A.M. Abraham L.J. Involvement of Sp1 and microsatellite repressor sequences in the transcriptional control of the human CD30 gene Am J Pathol 156 2000 1723-1731
17. Durkop H. Oberbarnscheidt M. Latza U. Bulfone-Paus S. Krause H. Pohl T. Stein H. Structure of the Hodgkin's lymphoma-associated human CD30 gene and the influence of a microsatellite region on its expression in CD30(+) cell lines Biochim Biophys Acta 1519 2001 185-191
18. Watanabe M. Ogawa Y. Ito K. Higashihara M. Kadin M.E. Abraham L.J. Watanabe T. Horie R. AP-1 mediated relief of repressive activity of the CD30 promoter microsatellite in Hodgkin and Reed-Sternberg cells Am J Pathol 163 2003 633-641
19. Chang L. Karin M. Mammalian MAP kinase signalling cascades Nature 410 2001 37-40
20. Mathas S. Hinz M. Anagnostopoulos I. Krappmann D. Lietz A. Jundt F. Bommert K. Mechta-Grigoriou F. Stein H. Dorken B. et al. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B EMBO J 21 2002 4104-4113
21. Duckett C.S. Gedrich R.W. Gilfillan M.C. Thompson C.B. Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2 Mol Cell Biol 17 1997 1535-1542
22. Harlin H. Podack E. Boothby M. Alegre M.L. TCR-independent CD30 signaling selectively induces IL-13 production via a TNF receptor-associated factor/p38 mitogen-activated protein kinase-dependent mechanism J Immunol 169 2002 2451-2459
23. Zheng B. Fiumara P. Li Y.V. Georgakis G. Snell V. Younes M. Vauthey J.N. Carbone A. Younes A. MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival Blood 102 2003 1019-1027
24. Vidalain P.O. Azocar O. Servet-Delprat C. Rabourdin-Combe C. Gerlier D. Manie S. CD40 signaling in human dendritic cells is initiated within membrane rafts EMBO J 19 2000 3304-3313
25. Eliopoulos A.G. Wang C.C. Dumitru C.D. Tsichlis P.N. Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40 EMBO J 22 2003 3855-3864
26. Hargreaves P.G. Al-Shamkhani A. Soluble CD30 binds to CD153 with high affinity and blocks transmembrane signaling by CD30 Eur J Immunol 32 2002 163-173
27. Haswell L.E. Glennie M.J. Al-Shamkhani A. Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154 Eur J Immunol 31 2001 3094-3100
28. Holler N. Tardivel A. Kovacsovics-Bankowski M. Hertig S. Gaide O. Martinon F. Tinel A. Deperthes D. Calderara S. Schulthess T. et al. Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex Mol Cell Biol 23 2003 1428-1440
29. Jungnickel B. Staratschek-Jox A. Brauninger A. Spieker T. Wolf J. Diehl V. Hansmann M.L. Rajewsky K. Kuppers R. Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma J Exp Med 191 2000 395-402
30. Horie R. Watanabe T. Morishita Y. Ito K. Ishida T. Kanegae Y. Saito I. Higashihara M. Mori S.Kadin M.E. Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells Oncogene 21 2002 2493-2503
31. Gruss H.J. Boiani N. Williams D.E. Armitage R.J. Smith C.A. Goodwin R.G. Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines Blood 83 1994 2045-2056
32. Mir S.S. Richter B.W. Duckett C.S. Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells Blood 96 2000 4307-4312
33. Levi E. Pfeifer W.M. Kadin M.E. CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest? Blood 98 2001 1630-1632
34. Hubinger G. Muller E. Scheffrahn I. Schneider C. Hildt E. Singer B.B. Sigg I. Graf J. Bergmann L. CD30-mediated cell cycle arrest associated with induced expression of p21(CIP1/WAF1) in the anaplastic large cell lymphoma cell line Karpas 299 Oncogene 20 2001 590-598
35. Grell M. Zimmermann G. Gottfried E. Chen C.M. Grunwald U. Huang D.C. Wu Lee Y.H. Durkop H. Engelmann H. Scheurich P. et al. Induction of cell death by tumour necrosis factor (TNF) receptor 2, CD40 and CD30: a role for TNF-R1 activation by endogenous membrane-anchored TNF EMBO J 18 1999 3034-3043
36. Duckett C.S. Thompson C.B. CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival Genes Dev 11 1997 2810-2821
37. Hansen H.P. Dietrich S. Kisseleva T. Mokros T. Mentlein R. Lange H.H. Murphy G. Lemke H. CD30 shedding from Karpas 299 lymphoma cells is mediated by TNF-alpha-converting enzyme J Immunol 165 2000 6703-6709
38. Peppel K. Crawford D. Beutler B. A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity J Exp Med 174 1991 1483-1489
39. Mohler K.M. Torrance D.S. Smith C.A. Goodwin R.G. Stremler K.E. Fung V.P. Madani H.Widmer M.B. Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists J Immunol 151 1993 1548-1561
40. Al-Shamkhani A. Mallett S. Brown M.H. James W. Barclay A.N. Affinity and kinetics of the interaction between soluble trimeric OX40 ligand, a member of the tumor necrosis factor superfamily, and its receptor OX40 on activated T cells J Biol Chem 272 1997 5275-5282
41. Siegel R.M. Frederiksen J.K. Zacharias D.A. Chan F.K. Johnson M. Lynch D. Tsien R.Y. Lenardo M.J. Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations Science 288 2000 2354-2357
42. Panus J.F. Smith C.A. Ray C.A. Smith T.D.Patel D.D. Pickup D.J. Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: a soluble, secreted CD30 homologue Proc Natl Acad Sci USA 99 2002 8348-8353
43. Saraiva M. Smith P. Fallon P.G. Alcami A. Inhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus J Exp Med 196 2002 829-839
44. Baud V. Karin M. Signal transduction by tumor necrosis factor and its relatives Trends Cell Biol 11 2001 372-377
45. Li Q. Verma I.M. NF-κB regulation in the immune system Nat Rev Immunol 2 2002 725-734
46. Aggarwal B. Signalling pathways of the TNF superfamily: a double-edged sword Nat Rev Immunol 3 2003 745-756