Inhibitors of Δ(24(25)) sterol methyltransferase block sterol synthesis and cell proliferation in Pneumocystis carinii

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 7, 1997, Pages 1428-1432

  Urbina, Julio A ^a,c   Visbal, Gonzalo ^a   Contreras, Lellys M ^a   McLaughlin, Gerald ^b   Docampo, Roberto ^c  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

22,26 AZASTEROL; CHOLESTA 8,14,24 TRIEN 3BETA OL; METHYLTRANSFERASE; UNCLASSIFIED DRUG; ZYMOSTEROL; 22,26-AZASTEROL; CHOLESTANOL; DELTA 24 STEROL METHYLTRANSFERASE; DELTA 24-STEROL METHYLTRANSFERASE; DRUG DERIVATIVE; ENZYME INHIBITOR; STEROL;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL PROLIFERATION; ENZYME INHIBITION; NONHUMAN; OPPORTUNISTIC INFECTION; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; STEROIDOGENESIS; ALKYLATION; BIOSYNTHESIS; CELL DIVISION; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; LUNG; METABOLISM; PNEUMOCYSTIS;

ALKYLATION; CELL DIVISION; CELL LINE; CHOLESTANOL; ENZYME INHIBITORS; HUMANS; LUNG; METHYLTRANSFERASES; PNEUMOCYSTIS; STEROLS;

EID: 0030611719     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.7.1428     Document Type: Article

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