Novel protein kinase C-epsilon inhibits human CYP11B2 gene expression through ERK1/2 signalling pathway and JunB

Journal of Molecular Endocrinology

Volumn 36, Issue 1, 2006, Pages 51-64

  LeHoux, Jean Guy ^a   Lefebvre, Andrée ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN II; BISINDOLYLMALEIMIDE; CHLORAMPHENICOL ACETYLTRANSFERASE; DIACYLGLYCEROL; GENE PRODUCT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN JUNB; PROTEIN KINASE C EPSILON; UNCLASSIFIED DRUG;

ADENOVIRUS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXPRESSION VECTOR; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ALDOSTERONE SYNTHASE; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA PRIMERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C-EPSILON; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-JUN; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 33244489584     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.1.01908     Document Type: Article

References (60)

1. Angel P & Karin M 1991 The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochimica et Biophysica Acta 1072 129-157.
2. Baines CP, Zhang J, Wang GW, Zheng YT, Xiu JX, Cardwell EM, Bolli R & Ping P 2002 Mitochondrial PKC-epsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKC-epsilon-MAPK interactions and differential MAPK activation in PKC-epsilon-induced cardioprotection. Circulation Research 90 390-397.
3. Bassett MH, Zhang Y, White PC & Rainey WE 2000 Regulation of human CYP11B2 and CYP11B1: comparing the role of the common CRE/Ad1 element. Endocrine Research 26 941-951.
4. Bassett MH, White PC & Rainey WE 2004 The regulation of aldosterone synthase expression. Molecular and Cellular Endocrinology 217 67-74.
5. Bollag WB, Barrett PQ, Isales CM & Rasmussen H 1991 Angiotensin-II-induced changes in diacylglycerol levels and their potential role in modulating the steroidogenic response. Endocrinology 128 231-241.
6. Chabre O, Cornillon F, Bottari SP, Chambaz EM & Vilgrain I 1995 Hormonal regulation of mitogen-activated protein kinase activity in bovine adrenocortical cells: cross-talk between phosphoinositides, adenosine 3′,5′-monophosphate, and tyrosine kinase receptor pathways. Endocrinology 136 956-964.
7. Cherradi N, Pardo B, Greenberg AS, Kraemer FB & Capponi AM 2003 Angiotensin II activates cholesterol ester hydrolase in bovine adrenal glomerulosa cells through phosphorylation mediated by p42/p44 mitogen-activated protein kinase. Endocrinology 144 4905-4915.
8. Clark AJ, Balla T, Jones MR & Catt KJ 1992 Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C. Molecular Endocrinology 6 1889-1898.
9. Clyne CD, White PC & Rainey WE 1996 Calcium regulates human CYP11B2 transcription. Endocrine Research 22 485-492.
10. Clyne CD, Zhang Y, Slutsker L, Mathis JM, White PC & Rainey WE 1997 Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements. Molecular Endocrinology 11 638-649.
11. Condon JC, Pezzi V, Drummond BM, Yin S & Rainey WE 2002 Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase. Endocrinology 143 3651-3657.
12. Coulombe N, Lefebvre A & LeHoux JG 1996 Characterization of the hamster CYP11B2 gene regulatory regions. Endocrine Research 22 653-661.
13. Coulombe N, Lefebvre A & Lehoux JG 1997 Characterization of the hamster CYP11B2 gene encoding adrenal cytochrome P450 aldosterone synthase. DNA Cell Biology 16 993-1002.
14. Cuevas BD, Uhlik MT, Garrington TP & Johnson GL 2005 MEKK1 regulates the AP-1 dimer repertoire via control of JunB transcription and Fra-2 protein stability. Oncogene 24 801-809.
15. Fong TH, Yang CC, Greenberg AS & Wang SM 2002 Immunocytochemical studies on lipid droplet-surface proteins in adrenal cells. Journal of Cell Biochemisty 86 432-439.
16. Garcia-Paramio P, Cabrerizo Y, Bornancin F & Parker PJ 1998 The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation. Biochemistry Journal 333 631-636.
17. Gu J, Wen Y, Mison A & Nadler JL 2003 12-Lipoxygenase pathway increases aldosterone production, 3′,5′-cyclic adenosine monophosphate response element-binding protein phosphorylation, and p38 mitogen-activated protein kinase activation in H295R human adrenocortical cells. Endocrinology 144 534-543.
18. Gudermann T, Grosse R & Schultz G 2000 Contribution of receptor/G protein signaling to cell growth and transformation. Naunyn Schmiedebergs Archives of Pharmacology 361 345-362.
19. Hajnóczky G, Várnai P, Buday L, Faragó A & Spät A 1992 The role of protein kinase-C in control of aldosterone production by rat adrenal glomerulosa cells: activation of protein kinase-C by stimulation with potassium. Endocrinology 130 2230-2236.
20. Heidkamp MC, Bayer AL, Martin JL & Samarel AM 2001 Differential activation of mitogen-activated protein kinase cascades and apoptosis by protein kinase C epsilon and delta in neonatal rat ventricular myocytes. Circulation Research 89 882-890.
21. Ho SN, Hunt HD, Horton RM, Pullen JK & Pease LR 1989 Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77 51-59.
22. Hunyady L, Baukal AJ, Bor M, Ely JA & Catt KJ 1990 Regulation of 1,2-diacylglycerol production by angiotensin-II in bovine adrenal glomerulosa cells. Endocrinology 126 1001-1008.
23. Kojima I, Shibata H & Ogata E 1986 Phorbol ester inhibits angiotensin-induced activation of phospholipase C in adrenal glomerulosa cells. Its implication in the sustained action of angiotensin. Biochemisty Journal 237 253-258.
24. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685.
25. LeHoux JG & Ducharme L 1995 In vivo effects of adrenocorticotropin on c-jun, jun-B, c-fos and fos-B in rat adrenal. Endocrine Research 21 267-274.
26. LeHoux JG & Lefebvre A 1998 Transcriptional activity of the hamster CYP11B2 promoter in NCI-H295 cells stimulated by angiotensin II, potassium, forskolin and bisindolylmaleimide. Journal of Molecular Endocrinology 20 183-191.
27. LeHoux JG & Lefebvre A 2004 On the control of the hCYP11B2 gene expressing cytochrome P450 aldosterone synthase. Endocrine Research 30 807-812.
28. LeHoux JG, Mason JI & Ducharme L 1992 In vivo effects of adrenocorticotropin on hamster adrenal steroidogenic enzymes. Endocrinology 131 1874-1882.
29. LeHoux JG, Bernard H, Ducharme L, Lefebvre A, Shapcott D, Tremblay A & Véronneau S 1996a The regulation of the formation of glucocorticoids and mineralocorticoids in vivo. In Advances in Molecular and Cell Biology, pp 149-201. Eds EE Bittar, CR Jefcoate. Greenwich, CT: Jai Press Inc.
30. LeHoux JG, Lefebvre A, Ducharme L, LeHoux J, Martel D & Briere N 1996b Some effects of a low sodium intake on the expression of P450 aldosterone synthase in the hamster adrenal cortex: immunoblotting, immunofluorescent and immuno-gold electron microscopic studies. Journal of Endocrinology 149 341-349.
31. LeHoux JG, Dupuis G & Lefebvre A 2000 Regulation of CYP11B2 gene expression by protein kinase C. Endocrine Research 26 1027-1031.
32. LeHoux JG, Dupuis G & Lefebvre A 2001 Control of CYP11B2 gene expression through differential regulation of its promoter by atypical and conventional protein kinase C isoforms. Journal of Biological Chemistry 276 8021-8028.
33. Li J, Feltzer RE, Dawson KL, Hudson EA & Clark BJ 2003 Janus kinase 2 and calcium are required for angiotensin II-dependent activation of steroidogenic acute regulatory protein transcription in H295R human adrenocortical cells. Journal of Biological Chemisty 278 52355-52362.
34. McNeill H, Puddefoot JR & Vinson GP 1998 MAP kinase in the rat adrenal gland. Endocrine Research 24 373-380.
35. Mellor H & Parker PJ 1998 The extended protein kinase C superfamily. Biochemisty Journal 332 281-292.
36. Natarajan R, Dunn WD, Stern N & Nadler J 1990 Key role of diacylglycerol-mediated 12-lipoxygenase product formation in angiotensin II-induced aldosterone synthesis. Molecular and Cellular Endocrinology 72 73-80.
37. Natarajan R, Lanting L, Xu L & Nadler J 1994 Role of specific isoforms of protein kinase C in angiotensin II and lipoxygenase action in rat adrenal glomerulosa cells. Molecular and Cellular Endocrinology 101 59-66.
38. Natarajan R, Yang DC, Lanting L & Nadler JL 2002 Key role of P38 mitogen-activated protein kinase and the lipoxygenase pathway in angiotensin II actions in H295R adrenocortical cells. Endocrine 18 295-301.
39. Naville D, Bordet E, Berthelon MC, Durand P & Begeot M 2001 Activator protein-1 is necessary for angiotensin-II stimulation of human adrenocorticotropin receptor gene transcription. European Journal of Biochemisty 268 1802-1810.
40. Ni CW, Wang DL, Lien SC, Cheng JJ, Chao YJ & Hsieh HJ 2003 Activation of PKC-epsilon and ERK1/2 participates in shear-induced endothelial MCP-1 expression that is repressed by nitric oxide. Journal of Cell Physiology 195 428-434.
41. Osman H, Murigande C, Nadakal A & Capponi AM 2002 Repression of DAX-1 and induction of SF-1 expression. Two mechanisms contributing to the activation of aldosterone biosynthesis in adrenal glomerulosa cells. Journal of Biological Chemistry 277 41259-41267.
42. Parekh DB, Ziegler W & Parker PJ 2000 Multiple pathways control protein kinase C phosphorylation. EMBO Journal 19 496-503.
43. Pascoe L, Jeunemaitre X, Lebrethon MC, Curnow KM, Gomez-Sanchez CE, Gasc JM, Saez JM & Corvol P 1995 Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree. Journal of Clinical Investigations 96 2236-2246.
44. Pears CJ, Kour G, House C, Kemp BE & Parker PJ 1990 Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation. European Journal of Biochemisty 194 89-94.
45. Poole AW, Pula G, Hers I, Crosby D & Jones ML 2004 PKC-interacting proteins: from function to pharmacology. Trends in Pharmacological Science 25 528-535.
46. Rainey WE & Mrotek JJ 1998 Human adrenocortical cell lines: model systems to study steroid hormone synthesis. In Human Cell Culture, Human Cancer Cell Lines. Ed. J Masters. Dordrecht: Kluwer Academic Press 1 123-135.
47. Rainey WE, Bird IM & Mason JI 1994 The NCI-H295 cell line: a pluripotent model for human adrenocortical studies. Molecular and Cellular Endocrinology 100 45-50.
48. Rao VU, Shiraishi H & McDermott PJ 2004 PKC-epsilon regulation of extracellular signal-regulated kinase: a potential role in phenylephrine-induced cardiocyte growth. American Journal of Physiology, Heart Circulation Physiology 286 H2195-H2203.
49. Reyland ME 1993 Protein kinase C is a tonic negative regulator of steroidogenesis and steroid hydroxylase gene expression in Y1 adrenal cells and functions independently of protein kinase A. Molecular Endocrinology 7 1021-1030.
50. Sarazin P, Lefebvre A & LeHoux JG 1998 The role of calcium channels in hamster CYP11B2 gene expression. Endocrine Research 24 633-636.
51. Schreiber E, Matthias P, Muller MM & Schaffner W 1989 Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Research 17 6419.
52. Shaulian E & Karin M 2001 AP-1 in cell proliferation and survival. Oncogene 20 2390-2400.
53. 2+ influx. Endocrinology 140 1385-1391.
54. Spät A & Hunyady L 2004 Control of aldosterone secretion: a model for convergence in cellular signaling pathways. Physiological Reviews 84 489-539.
55. Staels B, Hum DW & Miller WL 1993 Regulation of steroidogenesis in NCI-H295 cells: a cellular model of the human fetal adrenal. Molecular Endocrinology 7 423-433.
56. Strait JB 3rd, Martin JL, Bayer A, Mestril R, Eble DM & Samarel AM 2001 Role of protein kinase C-epsilon in hypertrophy of cultured neonatal rat ventricular myocytes. American Journal of Physiology, Heart Circulation Physiology 280 H756-H766.
57. Suzuki J, Otsuka F, Inagaki K, Takeda M, Ogura T & Makino H 2004 Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells. Endocrinology 145 639-649.
58. Tian Y, Smith RD, Balla T & Catt KJ 1998 Angiotensin II activates mitogen-activated protein kinase via protein kinase C and Ras/Raf-1 kinase in bovine adrenal glomerulosa cells. Endocrinology 139 1801-1809.
59. Watanabe G, Lee RJ, Albanese C, Rainey WE, Batlle D & Pestell RG 1996 Angiotensin II activation of cyclin D1-dependent kinase activity. Journal of Biological Chemisty 271 22570-22577.
60. Yan S & Wenner CE 2001 Modulation of cyclin D1 and its signaling components by the phorbol ester TPA and the tyrosine phosphatase inhibitor vanadate. Journal of Cell Physiology 186 338-349.