12-Lipoxygenase pathway increases aldosterone production, 3′,5′-cyclic adenosine monophosphate response element-binding protein phosphorylation, and p38 mitogen-activated protein kinase activation in H295R human adrenocortical cells

Endocrinology

Volumn 144, Issue 2, 2003, Pages 534-543

  Gu, Jiali ^a   Wen, Yeshao ^a   Mison, Angeles ^a   Nadler, Jerry L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYEICOSATETRANOIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 1; ALDOSTERONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN; ARACHIDONATE 12 LIPOXYGENASE; BAICALEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME P450; ICOSATETRAENOIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADRENAL GLAND; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME REGULATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLOMERULOSA CELL; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; LEUKOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYNTHESIS;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ACTIVATING TRANSCRIPTION FACTOR 1; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADRENAL CORTEX; ALDOSTERONE; ALDOSTERONE SYNTHASE; ANGIOTENSIN II; ARACHIDONATE 12-LIPOXYGENASE; CARRIER PROTEINS; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HUMANS; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; TRANSCRIPTION FACTORS; VASOCONSTRICTOR AGENTS;

EID: 0037318599     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220580     Document Type: Article

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