Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements

Molecular Endocrinology

Volumn 11, Issue 5, 1997, Pages 638-649

  Clyne, Colin D ^a   Zhang, Yin ^a   Slutsker, Liliya ^a   Mathis, J Michael ^a   White, Perrin C ^a   Rainey, William E ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE SYNTHASE; ANGIOTENSIN; CIS ACTING ELEMENT; CYCLIC AMP; DEOXYCORTICOSTERONE; POTASSIUM ION; TRANSCRIPTION FACTOR;

ALDOSTERONE RELEASE; ARTICLE; CALCIUM TRANSPORT; DNA FLANKING REGION; ELECTROPHORETIC MOBILITY; HUMAN; HUMAN CELL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROMOTER REGION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TRANSCRIPTION REGULATION;

EID: 0030969421     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.5.9920     Document Type: Article

References (51)

1. Lifton RP 1995 Genetic determinants of human hypertension. Proc Natl Acad Sci USA 92:8545-8451
2. White PC 1994 Disorders of aldosterone biosynthesis and action. N Engl J Med 331:250-258
3. Hall JE (1991) The renin-angiotensin system: renal actions and blood pressure regulation. ComprTher 17:8-17
4. Quinn SJ, Williams GH 1992 Regulation of aldosterone secretion. In: James VHT (ed) The Adrenal Gland. Raven Press, New York, pp 159-189
5. Aguilera G 1993 Factors controlling steroid biosynthesis in the zona glomerulosa of the adrenal. J Steroid Biochem Mol Biol 45:147-151
6. Quinn SJ, Williams GH 1988 Regulation of aldosterone secretion. Annu Rev Physiol 50:409-426
7. Ogishima T, Suzuki H, Hata J, Mitani F, Ishimura Y 1992 Zone-specific expression of aldosterone synthase cytochrome P-450 and cytochrome P-450 11β in rat adrenal cortex: histochemical basis for the functional zonation. Endocrinology 130:2971-2977
8. Yabu M, Senda T, Nonaka Y, Matsukawa N, Okamoto M, Fujita H 1991 Localization of the gene transcripts of 11β-hydroxylase and aldosterone synthase in the rat adrenal cortex by in situ hybridization. Histochemistry 96:391-394
9. Domalik LJ, Chaplin DD, Kirkman MS, Wu RC, Liu W, Howard TA, Seldin MF, Parker KL 1991 Different isozymes of mouse 11β-hydroxylase produce mineralocorticoids and glucocorticoids. Mol Endocrinol 5:1853-1861
10. 11β. Biochem Biophys Res Commun 169:245-252
11. Lehoux J, Mason JI, Bernard H, Ducharme L, Lehoux J, Véronneau S, Lefebvre A 1994 The presence of two cytochrome P450 aldosterone synthase mRNAs in the hamster adrenal. J Steroid Biochem Mol Biol 49:131-137
12. Curnow KM, Tusie-Luns M, Pascoe L, Natajaran R, Gu J, Nadler JL, White PC 1991 The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex. Mol Endocrinol 5:1513-1522
13. 11β). J Biol Chem 264:20961-20967
14. White PC, Curnow KM, Pascoe L 1994 Disorders of steroid 11 beta-hydroxylase isozymes. Endocr Rev 15:421-438
15. Kawamoto T, Mitsuuchi Y, Toda K, Yokoyama Y, Miyahara K, Miura S, Ohnishi T, Ichikawa Y, Nakao K, Imura H, Ulick S, Shizuta, Y 1992 Role of steroid 11β-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans. Proc Natl Acad Sci USA 89:1458-1462
16. Mukai K, Imai M, Shimada H, Ishimura Y 1993 Isolation and characterization of rat CYP11B genes involved in late steps of mineralo- and glucocorticoid syntheses. J Biol Chem 268:9130-9137
17. Rice DA, Aitkan LD, Vandedbark GR, Mouw AR, Franklin A, Schimmer BP, Parker KL 1989 A cAMP-responsive element regulates expression of the mouse steroid 11β-hydroxylase gene. J Biol Chem 264:14011-14015
18. Bogerd AM, Franklin A, Rice DA, Schimmer BP, Parker KL 1990 Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11β-hydroxylase. Mol Endocrinol 4:845-850
19. Mouw AR, Rice DA, Meade JC, Chua SC, White PC, Schimmer BP, Parker KL 1989 Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11β-hydroxylase. J Biol Chem 264:1305-1309
20. Kirita S, Hashimoto T, Kitajima M, Honda S, Morohashi K, Omura T 1990 Structural analysis of multiple bovine P-450(11β) genes and their promoter activities. J Biochem 108:1030-1041
21. Honda S, Morohashi K, Omura T 1990 Novel cAMP regulatory elements in the promoter region of bovine P450(11β) gene. J Biochem 108:1042-1049
22. Hashimoto T, Morohashi K, Takayama K, Honda S, Wada T, Handa H, Omura T (1992) Cooperative transcriptional activation between Ad1, a CRE-like element, and other elements in the CYP11B gene promoter. J Biochem 112:573-575
23. Abayasekara DR, Vazir H, Whitehouse BJ, Price GM, Hinson JP, Vinson GP 1989 Studies on the mechanisms of ACTH-induced inhibition of aldosterone biosynthesis in the rat adrenal cortex. J Endocrinol 122:625-632
24. Fuchs-Hammoser R, Schweigwe M, Oelkers W 1980 The effect of chronic low-dose infusion of ACTH (1-24) on renin, renin substrate, aldosterone and other corticosteroids in sodium replete and deplete man. Acta Endocrinol (Copenh) 95:198-206
25. 11β in rat adrenals: separate regulation of gene expression. Mol Cell Endocrinol 91:201-209
26. Bird IM, Walker SW, Williams BC 1990 Agonist-stimulated turnover of the phosphoinositides and the regulation of the adrenocortical steroidogenesis. J Mol Endocrinol 5:191-209
27. Bird IM, Hanley NA, Word RA, Mathis JM, McCarthy JL, Mason JI, Rainey WE 1994 Human NCI-H295 adrenocortical carcinoma cells: a model for angiotensin II-responsive aldosterone secretion. Endocrinology 133: 1555-1561
28. Holland OB, Mathis JM, Bird IM, Rainey WE 1993 Angiotensin increases aldosterone synthase mRNA levels in human NCI-H295 cells. Mol Cell Endocrinol 94:R9-R13
29. 2+-regulated expression of steroid hydroxylases in H295R human adrenocortical cells. Endocrinology 136:5677-5684
30. Denner K, Rainey WE, Pezzi V, Bird IM, Bernhardt R, Mathis JM 1996 Differential regulation of 11β-hydroxylase and aldosterone synthase in human adrenocortical H295R cells. Mol Cell Endocrinol 121:87-91
31. Allen RG, Carey C, Parker JD, Mortrud MT, Mellon SH, Low MJ 1995 Targeted ablation of pituitary pre-opiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland. Mol Endocrinol 9:1005-1016
32. Clyne CD, White, PC, Rainey WE 1996 Calcium regulates human CYP11B2 transcription. Endocr Res 22:485-492
33. Schwaninger M, Lux G, Blume R, Oetjen E, Hikada H, Knepel W 1993 Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element. J Biol Chem 268:5168-5177
34. Eckert B, Schwaninger M, Knepel W 1993 Calcium-mobilizing insulin secretagogues stimulate transcription that is directed by the cyclic adenosine 3′,5′-monophosphate/calcium response element in a pancreatic islet beta-cell line. Endocrinology 137:225-233
35. Gonzalez GA, Yamamoto KK, Fischer WH, Montminy MR 1989 A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature 337:749-752
36. Lee CQ, Yun Y, Hoeffler JP, Habener JF 1990 Cyclic AMP responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO J 9:4455-4465
37. 2+/calmodulin-dependent protein kinases type I, II, and IV. J Biol Chem 271:3066-3073
38. Papadopoulos V, Brown AS, Hall PF 1990 Calcium-calmodulin-dependent phosphorylation of cytoskeletal proteins from adrenal cells. Mol Cell Endocrinol 74:109-123
39. 2+ signaling. Am J Physiol 38:F751-F760
40. 2+/calmodulin-dependent protein kinase II inhibitor, on adrenocortical cell aldosterone production. Endocr Res 21:259-295
41. Pezzi V, Clark BJ, Ando S, Stocco DM, Rainey WE 1996 Role of Calmodulin-dependent protein kinase II in acute adrenal aldosterone production. J Steroid Biochem Mol Biol 58:417-424
42. Lala DS, Rice DA, Parker KL 1992 Steroidogenic factor 1, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor 1. Mol Endocrinol 6:1249-1258
43. Morohashi K, Honda S, Inomata Y, Handa H, Omura T 1992 A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s. J Biol Chem 267:17913-17919
44. Parker KL, Schimmer BP 1993 Transcriptional regulation of the adrenal steroidogenic enzymes. Trends Endocrinol Metab 4:46-50
45. Rice DA, Mouw AR, Bogerd AM, Parker KL 1991 A shared promoter element regulates the expression of three steroidogenic enzymes. Mol Endocrinol 5:1552-1561
46. Lund J, Bakke M 1995 Mutually exclusive interactions of two orphan nuclear receptors determine activity of a cyclic adenosine 3′,5′-monophosphate-responsive sequence in the bovine CYP17 gene. Mol Endocrinol 9:327-339
47. Langlois D, Saez JM, Begeot M 1990 Effects of angiotensin II on inositol phosphate accumulation and calcium influx in bovine adrenal or Y-1 tumor adrenal cells. Endocr Res 16:31-49
48. Es-souni Routhier M, Bournot P, Ramirez LC 1995 Aldosterone synthase activity in the Y-1 adrenal cell line. J Steroid Biochem Mol Biol 52:581-585
49. Dignam JD, Lebozitz RM, Roeder RG 1983 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489
50. Mietus SM, Sladek FM, Ginsburg GS, Kuo CF, Ladias JA, Darnell JJ, Karathanasis SK 1992 Antagonism between apolipoprotein AI, AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol Cell Biol 12:1708-1718
51. Wang L-H, Tsai SY, Cook RG, Beattie WG, Tsai M-J, O'Malley BW 1989 COUP transcription factor is a member of the steroid receptor superfamily. Nature 340:163-166