Some effects of a low sodium intake on the expression of P450 aldosterone synthase in the hamster adrenal cortex: Immunoblotting, immunofluorescent and immuno-gold electron microscopic studies

Journal of Endocrinology

Volumn 149, Issue 2, 1996, Pages 341-349

  LeHoux, J G ^a   Lefebvre, A ^a   Ducharme, L ^a   Lehoux, J ^a   Martel, D ^a   Briere N ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE SYNTHASE; CYTOCHROME P450;

ADRENAL CORTEX; ANIMAL TISSUE; ARTICLE; HAMSTER; MALE; NONHUMAN; PRIORITY JOURNAL; SODIUM INTAKE;

EID: 0029967203     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1490341     Document Type: Article

References (24)

1. Calvert R, Millane G & Beaulieu JF 1994 Immunolocalization of a mesenchymal antigen specific to the gastrointestinal tract Anatomical Record 240 358-366.
2. Domalik LJ, Chaplin DD, Kirman MS, Wu RC, Liu W, Howard TA, Seldin MF & Parker KL 1991 Different isoenzymes of mouse 11β-hydroxylase produce mineralocorticoids and glucocorticoids. Molecular Endocrinology 5 1853-1861
3. Giroud CJP, Stachenko J & Venning EH 1956 Secretion of aldosterone by the zona glomerulosa of rat adrenal glands incubated in vitro. Proceedings of the Society for Experimental Biology and Medicine 92 154-158.
4. Imai M, Shimada H, Okada Y, Matsushima-Hibiya Y, Ogishima T & Ishimura Y 1990 Molecular cloning of a cDNA encoding aldosterone synthase cytochrome P-450 in rat adrenal cortex. FEBS Letters 263 299-302.
5. Katsumoto T, Inaga S & Kurimura T 1993 A device for in situ embedding of monolayer culture in Lowicryl KM4. Journal of Electron Microscopy 42 205-207.
6. aldo as related to primary aldosteronism Biochemical and Biophysical Research Communications 173 309-316.
7. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685.
8. LeHoux JG & Tremblay A 1992 In vivo regulation of gene expression of enzymes controlling aldosterone synthesis in rat adrenal. Journal of Steroid Biochemistry and Molecular Biology 43 837-846.
9. LeHoux JG, Lefebvre A, Belisle S & Bellabarba D 1987 Adrenocorticotropin and the time of the day influence the amount and activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the hamster adrenal Endocrinology 120 2367-2374
10. LeHoux JG, Mason JI, Bernard H, Ducharme L, Lehoux J, Véronneau S & Lefebvre A 1994 The presence of two cytochrome P450 aldosterone synthase mRNAs in the hamster adrenal. Journal of Steroid Biochemistry and Molecular Biology 49 131-137.
11. Mitani F, Suzuki H, Hata J, Ogishima T, Shimada H & Ishimura Y 1994 A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex histochemical detection and possible physiological role. Endocrinology 135 431-438.
12. Mornet E, Dupont J, Vitek A & White PC 1989 Characterization of two genes encoding human steroid 11β-hydroxylase (P450-11β). Journal of Biological Chemistry 264 20961-20967.
13. Morohashi K, Nonaka Y, Kinta S, Hatano S, Takakusu A, Okamoto M & Omura T 1990 Enzymatic activities of P450(11β)s expressed by two cDNAs in COS-7 cells Journal of Biochemistry 107 635-640
14. Ogishima T, Suzuki H, Hata J, Mitam F & Ishimura Y 1992 Zone specific expression of aldosterone synthase cytochrome P-450 and cytochrome P-45011β in rat adrenal cortex: histochemical basis for functional zonation. Endocrinology 130 2971-2977.
15. Sandor T &. Mehdi AZ 1979 Steroids and evolution. In Hormones and Evolution, pp 1-61 Ed EJW Barrington London, New York, San Francisco. Academic Press Inc.
16. Sandor T, Fazekas AG & Robinson BH 1976 The biosynthesis of corticosteroids throughout the vertebrates. In General, Comparative and Clinical Endocrinology of the Adrenal Cortex, pp 25-142. Eds I Chester Jones & IW Henderson London Academic Press.
17. Stirling J W 1990 A review of labeling and preparation techniques. Journal of Histochemistry and Cytochemistry 38 145-157.
18. Towbin H, Staehelm T & Gordon J 1979 Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences of the USA 76 4350-4354.
19. Tremblay A & LeHoux JG 1989 Effects of low sodium and high potassium intakes on rat steroid metabolizing enzymes. 71st Annual Meeting of the Endocrine Society, Seattle, WA Abstract 1459.
20. Tremblay A & LeHoux JG 1992 Influence of captopril on adrenal cytochrome P-450 s and adrenodoxin expression in high potassium or low sodium intake. Journal of Steroid Biochemistry 41 799-802.
21. Tremblay A & LeHoux JG 1993 Transcriptional activation of adrenocortical steroidogenic genes by high potassium or low sodium intake. FEBS Letters 317 211-215.
22. Tremblay A, Waterman MR, Parker KL & LeHoux JG 1991 Regulation of rat adrenal messenger RNA and protein levels for cytochrome P-450 s and adrenodoxin by dietary sodium depletion of potassium intake. Journal of Biological Chemistry 266 2245-2251.
23. Tremblay A, Parker KL & LeHoux JG 1992 Dietary potassium supplementation and sodium restriction stimulate aldosterone synthase but not 11β-hydroxylase P-450 messenger ribonucleic acid accumulation in rat adrenals and require angiotensin II production. Endocrinology 130 3152-3158.
24. Yanagibashi K, Haniu M, Shively JE, Shen WH & Hall P 1986 The synthesis of aldosterone by the adrenal cortex, two zones (fasciculata and glomerulosa) possess one enzyme for 11β-, 18-hydroxylation, and aldehyde synthesis. Journal of Biological Chemistry 261 3556-3562.