Molecular mechanisms and binding site location for the noncompetitive antagonist crystal violet on nicotinic acetylcholine receptors

Biochemistry

Volumn 45, Issue 7, 2006, Pages 2014-2026

  Arias, Hugo R ^a   Bhumireddy, Pankaj ^a   Spitzmaul, Guillermo ^b   Trudell, James R ^c   Bouzat, Cecilia ^b  

^a WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

^b UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; CRYSTALS; FLUORESCENCE; MOLECULAR DYNAMICS; SPECTROSCOPIC ANALYSIS;

BINDING SITE LOCATION; FLUOROPHOR CRYSTAL VIOLET (CRV); NICOTINIC ACETYLCHOLINE RECEPTORS; PHENCYCLIDINE;

PROTEINS;

ACETYLCHOLINE; AMINE; AMOBARBITAL; CARBACHOL; CRYSTAL VIOLET; DICHOLINE SUBERATE; FLUORESCENT DYE; GLUTAMIC ACID; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PENTOBARBITAL; PHENCYCLIDINE DERIVATIVE; POLYETHYLENEIMINE; PROADIFEN; TETRACAINE; THIENYLCYCLOHEXYLPIPERIDINE; TRITIUM; UNCLASSIFIED DRUG;

ALLOSTERISM; ANALYSIS; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; ION CURRENT; ISOTOPE LABELING; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR STABILITY; MOUSE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SCHILD TYPE ANALYSIS; STEREOCHEMISTRY; TEMPERATURE; TORPEDO;

ALLOSTERIC REGULATION; AMOBARBITAL; ANIMALS; BINDING SITES; FLUORESCENT DYES; GENTIAN VIOLET; ION CHANNELS; MODELS, MOLECULAR; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PENTOBARBITAL; PHENCYCLIDINE; PROTEIN BINDING; PROTEIN CONFORMATION; QUATERNARY AMMONIUM COMPOUNDS; RECEPTORS, NICOTINIC; TEMPERATURE; TETRACAINE; THIOPHENES; TORPEDO; TRITIUM;

ANIMALIA;

EID: 33144482573     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051752e     Document Type: Article

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