메뉴 건너뛰기




Volumn 56, Issue 2, 1999, Pages 300-307

Identification of amino acids of the Torpedo nicotinic acetylcholine receptor contributing to the binding site for the noncompetitive antagonist [3H]tetracaine

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; CHOLINERGIC RECEPTOR STIMULATING AGENT; ION CHANNEL; ISOLEUCINE; LEUCINE; NICOTINIC RECEPTOR; TETRACAINE; VALINE;

EID: 0032771146     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.2.300     Document Type: Article
Times cited : (43)

References (35)
  • 1
    • 0027987062 scopus 로고
    • Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit
    • Akabas MH, Kaufmann C, Archdeacon P and Karlin A (1994) Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit. Neuron 13:919-927.
    • (1994) Neuron , vol.13 , pp. 919-927
    • Akabas, M.H.1    Kaufmann, C.2    Archdeacon, P.3    Karlin, A.4
  • 2
    • 0018573151 scopus 로고
    • Interaction of local anesthetics with Torpedo californica membrane-bound acetylcholine receptor
    • Blanchard SG, Elliott J and Raftery MA (1979) Interaction of local anesthetics with Torpedo californica membrane-bound acetylcholine receptor. Biochemistry 18: 5880-5884.
    • (1979) Biochemistry , vol.18 , pp. 5880-5884
    • Blanchard, S.G.1    Elliott, J.2    Raftery, M.A.3
  • 4
    • 0028326435 scopus 로고
    • Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: Secondary structure implications
    • Blanton MP and Cohen JB (1994) Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: Secondary structure implications. Biochemistry 33:2859-2872.
    • (1994) Biochemistry , vol.33 , pp. 2859-2872
    • Blanton, M.P.1    Cohen, J.B.2
  • 5
    • 0021378318 scopus 로고
    • Use of o-phthalaldehyde to reduce background during automated Edman degradation
    • Brauer AW, Oman CL and Margolies MN (1984) Use of o-phthalaldehyde to reduce background during automated Edman degradation. Anal Biochem 137:134-142.
    • (1984) Anal Biochem , vol.137 , pp. 134-142
    • Brauer, A.W.1    Oman, C.L.2    Margolies, M.N.3
  • 7
    • 0019155988 scopus 로고
    • Spectroscopic studies of cutaneous photosensitizing agents. I: Spin trapping of photolysis products from sulfanilamide, 4-aminobenzoic acid and related compounds
    • Chignell CF, Kalayanaraman B, Mason RP and Sik RH (1980) Spectroscopic studies of cutaneous photosensitizing agents. I: Spin trapping of photolysis products from sulfanilamide, 4-aminobenzoic acid and related compounds. Photochem Photobiol 32:563-671.
    • (1980) Photochem Photobiol , vol.32 , pp. 563-671
    • Chignell, C.F.1    Kalayanaraman, B.2    Mason, R.P.3    Sik, R.H.4
  • 9
    • 0027276473 scopus 로고
    • The ion channel of muscle and electric organ acetylcholine receptors: Differing affinities for noncompetitive inhibitors
    • Eterovic VA, Li L, Ferchmin PA, Lee YH, Hann RM, Rodriguez AD and McNamee MG (1993) The ion channel of muscle and electric organ acetylcholine receptors: Differing affinities for noncompetitive inhibitors. Cell Mol Neurobiol 13:111-121.
    • (1993) Cell Mol Neurobiol , vol.13 , pp. 111-121
    • Eterovic, V.A.1    Li, L.2    Ferchmin, P.A.3    Lee, Y.H.4    Hann, R.M.5    Rodriguez, A.D.6    McNamee, M.G.7
  • 10
    • 0029123899 scopus 로고
    • The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating
    • Filatov GN and White MM (1995) The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating. Mol Pharmacol 48:379-384.
    • (1995) Mol Pharmacol , vol.48 , pp. 379-384
    • Filatov, G.N.1    White, M.M.2
  • 11
    • 0021866610 scopus 로고
    • UV-induced photoproducts of para-aminobenzoic acid
    • Gasparro FP (1985) UV-induced photoproducts of para-aminobenzoic acid. Photodermatology 2:151-157.
    • (1985) Photodermatology , vol.2 , pp. 151-157
    • Gasparro, F.P.1
  • 15
    • 0022458822 scopus 로고
    • The ion channel of the nicotinic acetylcholine receptor is farmed by the homologous helices M II of the receptor subunits
    • Hucho F, Oberthur W and Lottspeich F (1986) The ion channel of the nicotinic acetylcholine receptor is farmed by the homologous helices M II of the receptor subunits. FEBS Lett 205:137-142.
    • (1986) FEBS Lett , vol.205 , pp. 137-142
    • Hucho, F.1    Oberthur, W.2    Lottspeich, F.3
  • 16
    • 0030011258 scopus 로고    scopus 로고
    • The emerging three-dimensional structure of a receptor: The nicotinic acetylcholine receptor
    • Hucho F, Tsetlin VI and Machold J (1996) The emerging three-dimensional structure of a receptor: The nicotinic acetylcholine receptor. Eur J Biochem 239:539-557.
    • (1996) Eur J Biochem , vol.239 , pp. 539-557
    • Hucho, F.1    Tsetlin, V.I.2    Machold, J.3
  • 18
    • 0025745108 scopus 로고
    • A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor
    • Imoto K, Konno T, Nakai J, Wang F, Mishina M and Numa S (1991) A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor. FEBS Lett 289:193-200.
    • (1991) FEBS Lett , vol.289 , pp. 193-200
    • Imoto, K.1    Konno, T.2    Nakai, J.3    Wang, F.4    Mishina, M.5    Numa, S.6
  • 19
    • 0029593370 scopus 로고
    • Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
    • Karlin A and Akabas MH (1995) Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron 15:1231-1244.
    • (1995) Neuron , vol.15 , pp. 1231-1244
    • Karlin, A.1    Akabas, M.H.2
  • 20
    • 0029163027 scopus 로고
    • Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
    • Labarca C, Nowak MW, Zhang HY, Tang LX, Deshpande P and Lester HA (1995) Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature (Lond) 376:514-516.
    • (1995) Nature (Lond) , vol.376 , pp. 514-516
    • Labarca, C.1    Nowak, M.W.2    Zhang, H.Y.3    Tang, L.X.4    Deshpande, P.5    Lester, H.A.6
  • 21
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond) 227:680-685.
    • (1970) Nature (Lond) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 22
    • 0025819979 scopus 로고
    • 3H]-Nicotine as an agonist photoaffinity label
    • 3H]-Nicotine as an agonist photoaffinity label. Biochemistry 30:6987-6997.
    • (1991) Biochemistry , vol.30 , pp. 6987-6997
    • Middleton, R.E.1    Cohen, J.B.2
  • 24
    • 0031781630 scopus 로고    scopus 로고
    • State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor: Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit
    • Pascual JM and Karlin A (1998) State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor: Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit. J Gen Physiol 111:717-739.
    • (1998) J Gen Physiol , vol.111 , pp. 717-739
    • Pascual, J.M.1    Karlin, A.2
  • 25
    • 0022972430 scopus 로고
    • Location of ligand binding sites on the nicotinic acetylcholine receptor α subunit
    • Pedersen SE, Dreyer EB and Cohen JB (1986) Location of ligand binding sites on the nicotinic acetylcholine receptor α subunit. J Biol Chem 261:13735-13743.
    • (1986) J Biol Chem , vol.261 , pp. 13735-13743
    • Pedersen, S.E.1    Dreyer, E.B.2    Cohen, J.B.3
  • 28
    • 0025195179 scopus 로고
    • 3H]chlorpromazine labels three amino acids of the acetylcholine receptor γ subunit: Implications for the α-helical organization of regions MII and for the structure of the ion channel
    • 3H]chlorpromazine labels three amino acids of the acetylcholine receptor γ subunit: Implications for the α-helical organization of regions MII and for the structure of the ion channel. Proc Natl Acad Sci USA 87:4675-4679.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4675-4679
    • Revah, F.1    Galzi, J.L.2    Giraudat, J.3    Haumont, P.-Y.4    Lederer, F.5    Changeux, J.-P.6
  • 29
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • Schagger H and von Jagow G (1987) Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166:368-379.
    • (1987) Anal Biochem , vol.166 , pp. 368-379
    • Schagger, H.1    Von Jagow, G.2
  • 31
    • 0027506299 scopus 로고
    • Nicotinic acetylcholine receptor at 9 A resolution
    • Unwin N (1993) Nicotinic acetylcholine receptor at 9 A resolution. J Mol Biol 229:1101-1124.
    • (1993) J Mol Biol , vol.229 , pp. 1101-1124
    • Unwin, N.1
  • 32
    • 0028921479 scopus 로고
    • Acetylcholine receptor channel imaged in the open state
    • Unwin N (1995) Acetylcholine receptor channel imaged in the open state. Nature (Lond) 373:37-43.
    • (1995) Nature (Lond) , vol.373 , pp. 37-43
    • Unwin, N.1
  • 33
    • 0025786180 scopus 로고
    • 125I]iodophenyl)diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor
    • 125I]iodophenyl)diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor. J Biol Chem 266:21595-21607.
    • (1991) J Biol Chem , vol.266 , pp. 21595-21607
    • White, B.H.1    Howard, S.2    Cohen, S.G.3    Cohen, J.B.4
  • 34
    • 0026625673 scopus 로고
    • Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic non-competitive antagonist
    • White BH and Cohen JB (1992) Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic non-competitive antagonist. J Biol Chem 267:15770-15783.
    • (1992) J Biol Chem , vol.267 , pp. 15770-15783
    • White, B.H.1    Cohen, J.B.2
  • 35
    • 0028568234 scopus 로고
    • A hydrophobic inhibitor of the nicotinic acetylcholine receptor acts on the resting state
    • Wu G, Raines DE and Miller KW (1994) A hydrophobic inhibitor of the nicotinic acetylcholine receptor acts on the resting state. Biochemistry 33:15375-15381.
    • (1994) Biochemistry , vol.33 , pp. 15375-15381
    • Wu, G.1    Raines, D.E.2    Miller, K.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.