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Volumn 55, Issue 3, 2006, Pages 308-309

Slipping the barrier: How variants in CARD15 could alter permeability of the intestinal wall and population health

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; CALPROTECTIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1; MURAMYL DIPEPTIDE; NUCLEOTIDE BINDING PROTEIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN 2; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 33144477510     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2005.076075     Document Type: Note
Times cited : (10)

References (37)
  • 1
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-6.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 2
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3
  • 3
    • 0035897904 scopus 로고    scopus 로고
    • Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
    • Hampe J, Cuthbert A, Croucher PJ, et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001;357:1925-8.
    • (2001) Lancet , vol.357 , pp. 1925-1928
    • Hampe, J.1    Cuthbert, A.2    Croucher, P.J.3
  • 4
    • 0036201577 scopus 로고    scopus 로고
    • CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
    • Lesage S, Zouali H, Cezard JP, EPWG-IBD Group, EPIMAD Group, GETAID Group, et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 2002;70:845-57.
    • (2002) Am J Hum Genet , vol.70 , pp. 845-857
    • Lesage, S.1    Zouali, H.2    Cezard, J.P.3
  • 5
    • 0035895992 scopus 로고    scopus 로고
    • Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
    • Ogura Y, Inohara N, Benito A, et al. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem 2001;276:4812-18.
    • (2001) J Biol Chem , vol.276 , pp. 4812-4818
    • Ogura, Y.1    Inohara, N.2    Benito, A.3
  • 6
    • 2342583513 scopus 로고    scopus 로고
    • Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
    • Tanabe T, Chamaillard M, Ogura Y, et al. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J 2004;23:1587-97.
    • (2004) EMBO J , vol.23 , pp. 1587-1597
    • Tanabe, T.1    Chamaillard, M.2    Ogura, Y.3
  • 7
    • 0037380969 scopus 로고    scopus 로고
    • CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
    • Hisamatsu T, Suzuki M, Reinecker HC, et al. CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 2003;124:993-1000.
    • (2003) Gastroenterology , vol.124 , pp. 993-1000
    • Hisamatsu, T.1    Suzuki, M.2    Reinecker, H.C.3
  • 8
    • 0037379915 scopus 로고    scopus 로고
    • TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
    • Rosenstiel P, Fantini M, Brautigam K, et al. TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells. Gastroenterology 2003;124:1001-9.
    • (2003) Gastroenterology , vol.124 , pp. 1001-1009
    • Rosenstiel, P.1    Fantini, M.2    Brautigam, K.3
  • 9
    • 13244292161 scopus 로고    scopus 로고
    • Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
    • Kobayashi KS, Chamaillard M, Ogura Y, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005;307:731-4.
    • (2005) Science , vol.307 , pp. 731-734
    • Kobayashi, K.S.1    Chamaillard, M.2    Ogura, Y.3
  • 10
    • 13244277880 scopus 로고    scopus 로고
    • Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1 beta processing
    • Maeda S, Hsu LC, Liu H, et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1 beta processing. Science 2005;307:734-8.
    • (2005) Science , vol.307 , pp. 734-738
    • Maeda, S.1    Hsu, L.C.2    Liu, H.3
  • 11
    • 0034650930 scopus 로고    scopus 로고
    • Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors
    • Cario E, Rosenberg IM, Brandwein SL, et al. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J Immunol 2000;164:966-72.
    • (2000) J Immunol , vol.164 , pp. 966-972
    • Cario, E.1    Rosenberg, I.M.2    Brandwein, S.L.3
  • 12
    • 0035424901 scopus 로고    scopus 로고
    • Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
    • Abreu MT, Vora P, Faure E, et al. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol 2001;167:1609-16.
    • (2001) J Immunol , vol.167 , pp. 1609-1616
    • Abreu, M.T.1    Vora, P.2    Faure, E.3
  • 13
    • 0037018107 scopus 로고    scopus 로고
    • Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
    • Hornef MW, Frisan T, Vandewalle A, et al. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med 2001;195:559-70.
    • (2001) J Exp Med , vol.195 , pp. 559-570
    • Hornef, M.W.1    Frisan, T.2    Vandewalle, A.3
  • 14
    • 0037380969 scopus 로고    scopus 로고
    • CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
    • Hisamatsu T, Suzuki M, Reinecker HC, et al. CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 2003;124:993-1000.
    • (2003) Gastroenterology , vol.124 , pp. 993-1000
    • Hisamatsu, T.1    Suzuki, M.2    Reinecker, H.C.3
  • 15
    • 0037238970 scopus 로고    scopus 로고
    • Intestinal epithelial toll-like receptors: To protect. And serve?
    • Gewirtz AT. Intestinal epithelial toll-like receptors: to protect. And serve? Curr Pharm Des 2003;9:1-5.
    • (2003) Curr Pharm des , vol.9 , pp. 1-5
    • Gewirtz, A.T.1
  • 16
    • 0037381129 scopus 로고    scopus 로고
    • Intestinal epithelial cells and innate immunity in the intestine: Is CARD15/Nod2 another player?
    • Jobin C. Intestinal epithelial cells and innate immunity in the intestine: is CARD15/Nod2 another player? Gastroenterology 2003;124:1145-9.
    • (2003) Gastroenterology , vol.124 , pp. 1145-1149
    • Jobin, C.1
  • 17
    • 0032734313 scopus 로고    scopus 로고
    • Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium
    • O'Neil DA, Porter EM, Elewaut D, et al. Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol 1999;163:6718-24.
    • (1999) J Immunol , vol.163 , pp. 6718-6724
    • O'Neil, D.A.1    Porter, E.M.2    Elewaut, D.3
  • 18
    • 0012722659 scopus 로고    scopus 로고
    • Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
    • Girardin SE, Boneca IG, Viala J, et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 2003;278:8869-72.
    • (2003) J Biol Chem , vol.278 , pp. 8869-8872
    • Girardin, S.E.1    Boneca, I.G.2    Viala, J.3
  • 19
    • 0037458665 scopus 로고    scopus 로고
    • Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
    • Inohara N, Ogura Y, Fontalba A, et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003;278:5509-12.
    • (2003) J Biol Chem , vol.278 , pp. 5509-5512
    • Inohara, N.1    Ogura, Y.2    Fontalba, A.3
  • 20
    • 7244257312 scopus 로고    scopus 로고
    • NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal {alpha}-defensin expression
    • Wehkamp J, Harder J, Weichenthal M, et al. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal {alpha}-defensin expression. Gut 2004;53:1658-64.
    • (2004) Gut , vol.53 , pp. 1658-1664
    • Wehkamp, J.1    Harder, J.2    Weichenthal, M.3
  • 21
    • 3442899939 scopus 로고    scopus 로고
    • NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: Implications for Crohn's disease
    • Netea MG, Kullberg BJ, de Jong DJ, et al. NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease. Eur J Immunol 2004;34:2052-9.
    • (2004) Eur J Immunol , vol.34 , pp. 2052-2059
    • Netea, M.G.1    Kullberg, B.J.2    De Jong, D.J.3
  • 23
    • 0024462586 scopus 로고
    • Intestinal permeability in patients with Crohn's disease and their healthy relatives
    • Katz KD, Hollander D, Vadheim CM, et al. Intestinal permeability in patients with Crohn's disease and their healthy relatives. Gastroenterology 1989;97:927-31.
    • (1989) Gastroenterology , vol.97 , pp. 927-931
    • Katz, K.D.1    Hollander, D.2    Vadheim, C.M.3
  • 24
    • 0026573173 scopus 로고
    • Intestinal permeability in patients with Crohn's disease and their first degree relatives
    • Teahon K, Smethurst P, Levi AJ, et al. Intestinal permeability in patients with Crohn's disease and their first degree relatives. Gut 1992;33:320-3.
    • (1992) Gut , vol.33 , pp. 320-323
    • Teahon, K.1    Smethurst, P.2    Levi, A.J.3
  • 25
    • 0030823372 scopus 로고    scopus 로고
    • Clustering of increased small intestinal permeability in families with Crohn's disease
    • Peeters M, Geypens B, Claus D, et al. Clustering of increased small intestinal permeability in families with Crohn's disease. Gastroenterology 1997;113:802-7.
    • (1997) Gastroenterology , vol.113 , pp. 802-807
    • Peeters, M.1    Geypens, B.2    Claus, D.3
  • 26
    • 0033003669 scopus 로고    scopus 로고
    • Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: An inherited detect in mucosal defence?
    • Soderholm JD, Olaison G, Lindberg E, et al. Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited detect in mucosal defence? Gut 1999;44:96-100.
    • (1999) Gut , vol.44 , pp. 96-100
    • Soderholm, J.D.1    Olaison, G.2    Lindberg, E.3
  • 27
    • 13844307903 scopus 로고    scopus 로고
    • Genetic aspects of intestinal permeability in inflammatory bowel disease
    • Takeuchi K, Maiden L, Bjarnason I. Genetic aspects of intestinal permeability in inflammatory bowel disease. Novartis Found Symp. 2004;263:151-8, 159-63, and 211-18).
    • (2004) Novartis Found Symp , vol.263 , pp. 151-158
    • Takeuchi, K.1    Maiden, L.2    Bjarnason, I.3
  • 28
    • 0038724272 scopus 로고    scopus 로고
    • Subclinical intestinal inflammation: An inherited abnormality in Crohn's disease relatives?
    • Thjodleifsson B, Sigthorsson G, Cariglia N, et al. Subclinical intestinal inflammation: an inherited abnormality in Crohn's disease relatives? Gastroenterology 2003;124:1728-37.
    • (2003) Gastroenterology , vol.124 , pp. 1728-1737
    • Thjodleifsson, B.1    Sigthorsson, G.2    Cariglia, N.3
  • 29
    • 0027217379 scopus 로고
    • Intestinal permeability and the prediction of relapse in Crohn's disease
    • Wyatt J, Vogelsang H, Hubl W, et al. Intestinal permeability and the prediction of relapse in Crohn's disease. Lancet 1993;341:1437-9.
    • (1993) Lancet , vol.341 , pp. 1437-1439
    • Wyatt, J.1    Vogelsang, H.2    Hubl, W.3
  • 30
    • 0033528272 scopus 로고    scopus 로고
    • Tumor necrosis factor-α and interleukin 1β in relapse of Crohn's disease
    • Schreiber S, Nikolaus S, Hampe J, et al. Tumor necrosis factor-α and interleukin 1β in relapse of Crohn's disease. Lancet 1999;353:459-61.
    • (1999) Lancet , vol.353 , pp. 459-461
    • Schreiber, S.1    Nikolaus, S.2    Hampe, J.3
  • 31
    • 0034234796 scopus 로고    scopus 로고
    • Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease
    • Tibble JA, Sigthorsson G, Bridger S, et al. Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease. Gastroenterology 2000;119:15-22.
    • (2000) Gastroenterology , vol.119 , pp. 15-22
    • Tibble, J.A.1    Sigthorsson, G.2    Bridger, S.3
  • 32
    • 0033818743 scopus 로고    scopus 로고
    • Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis
    • Gitter AH, Bendfeldt K, Schulzke JD, et al. Leaks in the epithelial barrier caused by spontaneous and TNF-alpha-induced single-cell apoptosis. FASEB J 2000;14:1749-53.
    • (2000) FASEB J , vol.14 , pp. 1749-1753
    • Gitter, A.H.1    Bendfeldt, K.2    Schulzke, J.D.3
  • 33
    • 0345447585 scopus 로고    scopus 로고
    • Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
    • Bruewer M, Luegering A, Kucharzik T, et al. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J Immunol 2003;171:6164-72.
    • (2003) J Immunol , vol.171 , pp. 6164-6172
    • Bruewer, M.1    Luegering, A.2    Kucharzik, T.3
  • 34
    • 4344700784 scopus 로고    scopus 로고
    • Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment
    • Zeissig S, Bojarski C, Buergel N, et al. Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment. Gut 2004;53:1295-302.
    • (2004) Gut , vol.53 , pp. 1295-1302
    • Zeissig, S.1    Bojarski, C.2    Buergel, N.3
  • 35
    • 9344257937 scopus 로고    scopus 로고
    • Increased gut permeability in Crohn's disease: Is TNF the link?
    • Gibson PR. Increased gut permeability in Crohn's disease: is TNF the link? Gut 2004;53:1724-5.
    • (2004) Gut , vol.53 , pp. 1724-1725
    • Gibson, P.R.1
  • 36
    • 33144473772 scopus 로고    scopus 로고
    • Genetic basis for increased intestinal permeability in families with Crohn's disease: Role of CARD15 3020insC mutation?
    • Buhner S, Buning C, Genschel J, et al. Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation? Gut 2006;55:342-7.
    • (2006) Gut , vol.55 , pp. 342-347
    • Buhner, S.1    Buning, C.2    Genschel, J.3
  • 37
    • 12144287610 scopus 로고    scopus 로고
    • The NOD2 3020insC mutation and the risk of colorectal cancer
    • Kurzawski G, Suchy J, Kladny J, et al. The NOD2 3020insC mutation and the risk of colorectal cancer. Cancer Res 2004;64:1604-6.
    • (2004) Cancer Res , vol.64 , pp. 1604-1606
    • Kurzawski, G.1    Suchy, J.2    Kladny, J.3


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