CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA

European Journal of Immunology

Volumn 36, Issue 2, 2006, Pages 431-436

  Yasuda, Kei ^a   Rutz, Mark ^a   Schlatter, Beatrix ^a   Metzger, Jochen ^b   Luppa, Peter B ^b   Schmitz, Frank ^a   Haas, Tobias ^a   Heit, Antje ^a   Bauer, Stefan ^a,c   Wagner, Hermann ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Endosomal translocation; Interferon; Phospodiester DNA; TLR9

Indexed keywords

ALPHA INTERFERON; CD40 ANTIGEN; CD69 ANTIGEN; CELL DNA; CPG OLIGODEOXYNUCLEOTIDE; FLT3 LIGAND; INTERLEUKIN 6; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CYTOKINE PRODUCTION; DENDRITIC CELL; DNA BINDING; DNA CONTENT; DNA DETERMINATION; DNA MODIFICATION; DNA SEQUENCE; DNA STRUCTURE; DNA TRANSFER; ENDOSOME; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STABILITY; SURFACE PLASMON RESONANCE; UPREGULATION;

ANIMALS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CPG ISLANDS; DENDRITIC CELLS; DNA, SINGLE-STRANDED; ENDOSOMES; MICE; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN BINDING; SURFACE PLASMON RESONANCE; TOLL-LIKE RECEPTOR 9;

EID: 32944462310     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535210     Document Type: Article

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