Identification of a small molecule that induces mitotic arrest using a simplified high-content screening assay and data analysis method

Journal of Biomolecular Screening

Volumn 11, Issue 1, 2006, Pages 21-28

  Wilson, Christopher J ^a   Si, Ying ^a   Thompsons, Craig M ^a,b   Smellie, Andrew ^a   Ashwell, Mark A ^a   Liu, Ji Feng ^a   Ye, Ping ^a   Yohannes, Daniel ^a   Ng, Shi Chung ^a  

^a ARQULE INC   (United States)

^b CELL SIGNALING TECHNOLOGY   (United States)

Author keywords

High content screening; Image based screening; Mitotic arrest; Tubulin

Indexed keywords

ANTINEOPLASTIC AGENT; DNA; HISTONE H3; NOCODAZOLE; PACLITAXEL; VINBLASTINE;

ARTICLE; CANCER CELL; CELL PROLIFERATION; DATA ANALYSIS; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SENSITIVITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMAGING SYSTEM; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS INHIBITION; PRIORITY JOURNAL; STAINING; STATISTICAL ANALYSIS;

BIOLOGICAL ASSAY; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MITOSIS; PACLITAXEL; QUINAZOLINES; RESEARCH DESIGN; TUBULIN; TUMOR CELLS, CULTURED;

MAMMALIA;

EID: 32844460056     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057105280726     Document Type: Article

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