High-content screening and profiling of drug activity in an automated centrosome-duplication assay

ChemBioChem

Volumn 6, Issue 1, 2005, Pages 145-151

  Perlman, Zachary E ^a   Mitchison, Timothy J ^a   Mayer, Thomas U ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Independent Research Group   (Germany)

Author keywords

Bioinformatics; Biological information; Centrosomes; Drugs; High throughput screening

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALSTERPAULLONE; ANISOMYCIN; BAFILOMYCIN A1; CALCIMYCIN; CAMPTOTHECIN; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CYCLOHEXIMIDE; CYTOCHALASIN D; DACTINOMYCIN; EMETINE; GO 6796; GRAMICIDIN; LATRUNCULIN B; LEPTOMYCIN B; MENADIONE; MONENSIN; NOCODAZOLE; OLIGOMYCIN; PACLITAXEL; PROTEIN KINASE C INHIBITOR; RECEPTOR BLOCKING AGENT; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR ANTAGONIST; RILUZOLE; STAUROSPORINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALINOMYCIN; WORTMANNIN;

ACCURACY; ANIMAL CELL; ARTICLE; ASSAY; AUTOMATION; BIOINFORMATICS; CELL CYCLE; CELL ORGANELLE; CENTROSOME; CENTROSOME DUPLICATION ASSAY; CHEMICAL GENETICS; CONTROLLED STUDY; CYTOMETRY; DRUG ACTIVITY; DRUG MECHANISM; DRUG TARGETING; GENOMIC INSTABILITY; HIGH THROUGHPUT SCREENING; IMAGING; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANIMALS; BIOLOGICAL ASSAY; CELLS, CULTURED; CENTROSOME; COMPUTATIONAL BIOLOGY; DRUG EVALUATION, PRECLINICAL;

ANIMALIA;

EID: 12344253075     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400266     Document Type: Article

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