-
1
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz, P., Hu, E., and Spiegelman, B.M.: Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell, 79, 1147-1156, 1994.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
2
-
-
0030835678
-
The organization, promoter analysis, and expression of the human PPARγ gene
-
Fajas, L., Auboeuf, D., Raspe, E., Schoonjans, K., Lefebvre, A.M., Saladin, R., Najib, J., Laville, M., Fruchart, J.C., Deeb, S., Vidal-Puig, A., Flier, J., Briggs, M.R., Staels, B., Vidal, H., and Auwerx, J.: The organization, promoter analysis, and expression of the human PPARγ gene. J. Biol. Chem., 272, 18779-18789, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeuf, D.2
Raspe, E.3
Schoonjans, K.4
Lefebvre, A.M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
3
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne, B. and Wahli, W.: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev., 20, 649-688, 1999.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
4
-
-
0027525576
-
The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs
-
Issemann, I., Prince, R.A., Tugwood, J.D., and Green, S.: The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J. Mol. Endocrinol., 11, 37-47, 1993.
-
(1993)
J. Mol. Endocrinol.
, vol.11
, pp. 37-47
-
-
Issemann, I.1
Prince, R.A.2
Tugwood, J.D.3
Green, S.4
-
5
-
-
0036843143
-
A new selective peroxisome proliferator-activated receptor γ antagonist with antiobesity and antidiabetic activity
-
Rieusset, J., Touri, F., Michalik, L., Escher, P., Desvergne, B., Niesor, E., and Wahli, W.: A new selective peroxisome proliferator-activated receptor γ antagonist with antiobesity and antidiabetic activity. Mol. Endocrinol., 16, 2628-2644, 2002.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 2628-2644
-
-
Rieusset, J.1
Touri, F.2
Michalik, L.3
Escher, P.4
Desvergne, B.5
Niesor, E.6
Wahli, W.7
-
6
-
-
0032475922
-
Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages
-
Chinetti, G., Griglio, S., Antonucci, M., Torra, I.P., Delerive, P., Majd, Z., Fruchart, J.C., Chapman, J., Najib, J., and Staels, B.: Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages. J. Biol. Chem., 273, 25573-25580, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25573-25580
-
-
Chinetti, G.1
Griglio, S.2
Antonucci, M.3
Torra, I.P.4
Delerive, P.5
Majd, Z.6
Fruchart, J.C.7
Chapman, J.8
Najib, J.9
Staels, B.10
-
7
-
-
0035936763
-
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
-
Saltiel, A.R.: New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell, 104, 517-529, 2001.
-
(2001)
Cell
, vol.104
, pp. 517-529
-
-
Saltiel, A.R.1
-
8
-
-
0026517010
-
Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer, C., Krey, G., Keller, H., Givel, F., Helftenbein, G., and Wahli, W.: Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell, 68, 879-887, 1992.
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, C.1
Krey, G.2
Keller, H.3
Givel, F.4
Helftenbein, G.5
Wahli, W.6
-
9
-
-
0027504874
-
Identification of two mPPAR related receptors and evidence for the existence of five subfamily members
-
Chen, F., Law, S.W., and O'Malley, B.W.: Identification of two mPPAR related receptors and evidence for the existence of five subfamily members. Biochem. Biophys. Res. Commun., 196, 671-677, 1993.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.196
, pp. 671-677
-
-
Chen, F.1
Law, S.W.2
O'Malley, B.W.3
-
10
-
-
0033213637
-
PPARγ is required for placental, cardiac, and adipose tissue development
-
Barak, Y., Nelson, M.C., Ong, E.S., Jones, Y.Z., Ruiz-Lozano, P., Chien, K.R., Koder, A., and Evans, R.M.: PPARγ is required for placental, cardiac, and adipose tissue development. Mol. Cell, 4, 585-595, 1999.
-
(1999)
Mol. Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.M.8
-
11
-
-
0026517080
-
Enhancement of adipocyte differentiation by an insulin-sensitizing agent
-
Kletzien, R.F., Clarke, S.D., and Ulrich, R.G.: Enhancement of adipocyte differentiation by an insulin-sensitizing agent. Mol. Pharmacol., 41, 393-398, 1992.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 393-398
-
-
Kletzien, R.F.1
Clarke, S.D.2
Ulrich, R.G.3
-
12
-
-
0033212964
-
PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Komeda, K., Satoh, S., Nakano, R., Ishii, C., Sugiyama, T., Eto, K., Tsubamoto, Y., Okuno, A., Murakami, K., Sekihara, H., Hasegawa, G., Naito, M., Toyoshima, Y., Tanaka, S., Shiota, K., Kitamura, T., Fujita, T., Ezaki, O., Aizawa, S., and Kadowaki, T.: PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol. Cell, 4, 597-609, 1999.
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Tamemoto, H.4
Yamauchi, T.5
Komeda, K.6
Satoh, S.7
Nakano, R.8
Ishii, C.9
Sugiyama, T.10
Eto, K.11
Tsubamoto, Y.12
Okuno, A.13
Murakami, K.14
Sekihara, H.15
Hasegawa, G.16
Naito, M.17
Toyoshima, Y.18
Tanaka, S.19
Shiota, K.20
Kitamura, T.21
Fujita, T.22
Ezaki, O.23
Aizawa, S.24
Kadowaki, T.25
more..
-
13
-
-
0033213631
-
PPARγ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen, E.D., Sarraf, P., Troy, A.E., Bradwin, G., Moore, K., Milstone, D.S., Spiegelman, B.M., and Mortensen, R.M.: PPARγ is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell, 4, 611-617, 1999.
-
(1999)
Mol. Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
14
-
-
15844415080
-
Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice
-
Zhang, B., Graziano, M.P., Doebber, T.W., Leibowitz, M.D., White-Carrington, S., Szalkowski, D.M., Hey, P.J., Wu, M., Cullinan, C.A., Bailey, P., Lollmann, B., Frederich, R., Flier, J.S., Strader, C.D., and Smith, R.G.: Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in Zucker diabetic fatty rats and db/db mice. J. Biol. Chem., 271, 9455-9459, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9455-9459
-
-
Zhang, B.1
Graziano, M.P.2
Doebber, T.W.3
Leibowitz, M.D.4
White-Carrington, S.5
Szalkowski, D.M.6
Hey, P.J.7
Wu, M.8
Cullinan, C.A.9
Bailey, P.10
Lollmann, B.11
Frederich, R.12
Flier, J.S.13
Strader, C.D.14
Smith, R.G.15
-
15
-
-
0018652623
-
Recent studies of the 3T3-L1 adipocyte-like cell line
-
Rosen, O.M., Smith, C.J., Hirsch, A., Lai, E., and Rubin, C.S.: Recent studies of the 3T3-L1 adipocyte-like cell line. Recent Prog. Horm. Res., 35, 477-499, 1979.
-
(1979)
Recent Prog. Horm. Res.
, vol.35
, pp. 477-499
-
-
Rosen, O.M.1
Smith, C.J.2
Hirsch, A.3
Lai, E.4
Rubin, C.S.5
-
16
-
-
0018459915
-
DSM-III and schizophrenia: Diagnostic delight or nosological nightmare?
-
Nathan, RE.: DSM-III and schizophrenia: diagnostic delight or nosological nightmare? J. Clin. Psychol., 35, 477-479, 1979.
-
(1979)
J. Clin. Psychol.
, vol.35
, pp. 477-479
-
-
Nathan, R.E.1
-
17
-
-
0023031770
-
Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei
-
Narumiya, S., Ohno, K., Fujiwara, M., and Fukushima, M.: Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei. J. Pharmacol. Exp. Ther., 239, 506-511, 1986.
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.239
, pp. 506-511
-
-
Narumiya, S.1
Ohno, K.2
Fujiwara, M.3
Fukushima, M.4
-
18
-
-
0035053973
-
Cyclopentenone prostaglandins: New insights on biological activities and cellular targets
-
Straus, D.S. and Glass, C.K.: Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med. Res. Rev., 21, 185-210, 2001.
-
(2001)
Med. Res. Rev.
, vol.21
, pp. 185-210
-
-
Straus, D.S.1
Glass, C.K.2
-
19
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
-
Rossi, A., Kapahi, P., Natoli, G., Takahashi, T., Chen, Y., Karin, M., and Santoro, M.G.: Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase. Nature, 103-108, 2000.
-
(2000)
Nature
, pp. 103-108
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
Takahashi, T.4
Chen, Y.5
Karin, M.6
Santoro, M.G.7
-
20
-
-
0034712933
-
2 inhibits multiple steps in the NF-κB signaling pathway
-
2 inhibits multiple steps in the NF-κB signaling pathway. Proc. Natl. Acad. Sci. USA, 97, 4844-4849, 2000.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4844-4849
-
-
Straus, D.S.1
Pascual, G.2
Li, M.3
Welch, J.S.4
Ricote, M.5
Hsiang, C.H.6
Sengchanthalangsy, L.L.7
Ghosh, G.8
Glass, C.K.9
-
21
-
-
0142186679
-
2 and the ligation of PPARγ
-
2 and the ligation of PPARγ. J. Clin. Invest, 112, 945-955, 2003.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 945-955
-
-
Bell-Parikh, L.C.1
Ide, T.2
Lawson, J.A.3
McNamara, P.4
Reilly, M.5
FitzGerald, G.A.6
-
22
-
-
0142195899
-
Activation of nuclear receptors by prostaglandins
-
Ide, T., Egan, K., Bell-Parikh, L.C. and FitzGerald, G.A.: Activation of nuclear receptors by prostaglandins. Thromb. Res., 110, 311-315, 2003.
-
(2003)
Thromb. Res.
, vol.110
, pp. 311-315
-
-
Ide, T.1
Egan, K.2
Bell-Parikh, L.C.3
FitzGerald, G.A.4
-
23
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
-
Nolte, R.T., Wisely, G.B., Westin, S., Cobb, J.E., Lambert, M.H., Kurokawa, R., Rosenfeld, M.G., Willson, T.M., Glass, C.K., and Milburn, M.V.: Ligand binding and co-activator assembly of the peroxisome proliferator- activated receptor-γ. Nature, 395, 137-143, 1998.
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
Kurokawa, R.6
Rosenfeld, M.G.7
Willson, T.M.8
Glass, C.K.9
Milburn, M.V.10
-
25
-
-
17144381253
-
α, β-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor-γ
-
Shirald, T., Kamiya, N., Shiki, S., Kodama, T.S., Kakizuka, A., and Jingami, H.: α, β-Unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor-γ. J. Biol. Chem., 280, 14145-14153, 2005.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14145-14153
-
-
Shirald, T.1
Kamiya, N.2
Shiki, S.3
Kodama, T.S.4
Kakizuka, A.5
Jingami, H.6
-
26
-
-
0025336640
-
Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein
-
Lenz, M.L., Hughes, H., Mitchell, J.R., Via, D.P., Guyton, J.R., Taylor, A.A., Gotto, A.M. Jr., and Smith, C.V.: Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein. J. Lipid Res., 31, 1043-1050, 1990.
-
(1990)
J. Lipid Res.
, vol.31
, pp. 1043-1050
-
-
Lenz, M.L.1
Hughes, H.2
Mitchell, J.R.3
Via, D.P.4
Guyton, J.R.5
Taylor, A.A.6
Gotto Jr., A.M.7
Smith, C.V.8
-
27
-
-
0033105510
-
Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
-
Xu, H.E., Lambert, M.H., Montana, V.G., Parks, D.J., Blanchard, S.G., Brown, P.J., Sternbach, D.D., Lehmann, J.M., Wisely, G.B., Willson, T.M., Kliewer, S.A., and Milburn, M.V.: Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol. Cell, 3, 397-403, 1999.
-
(1999)
Mol. Cell
, vol.3
, pp. 397-403
-
-
Xu, H.E.1
Lambert, M.H.2
Montana, V.G.3
Parks, D.J.4
Blanchard, S.G.5
Brown, P.J.6
Sternbach, D.D.7
Lehmann, J.M.8
Wisely, G.B.9
Willson, T.M.10
Kliewer, S.A.11
Milburn, M.V.12
-
28
-
-
0035844217
-
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists
-
Davies, S.S., Pontsler, A.V., Marathe, G.K., Harrison, K.A., Murphy, R.C., Hinshaw, J.C., Prestwich, G.D., Hilaire, A.S., Prescott, S.M., Zimmerman, G.A., and McIntyre, T.M.: Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists. J. Biol. Chem., 276, 16015-16023, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16015-16023
-
-
Davies, S.S.1
Pontsler, A.V.2
Marathe, G.K.3
Harrison, K.A.4
Murphy, R.C.5
Hinshaw, J.C.6
Prestwich, G.D.7
Hilaire, A.S.8
Prescott, S.M.9
Zimmerman, G.A.10
McIntyre, T.M.11
-
29
-
-
0037422595
-
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
-
McIntyre, T.M., Pontsler, A.V., Silva, A.R., St Hilaire, A., Xu, Y., Hinshaw, J.C., Zimmerman, G.A., Hama, K., Aoki, J., Arai, H., and Prestwich, G.D.: Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist. Proc. Natl. Acad. Sci. USA, 100, 131-136, 2003.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 131-136
-
-
McIntyre, T.M.1
Pontsler, A.V.2
Silva, A.R.3
St. Hilaire, A.4
Xu, Y.5
Hinshaw, J.C.6
Zimmerman, G.A.7
Hama, K.8
Aoki, J.9
Arai, H.10
Prestwich, G.D.11
-
30
-
-
14044275170
-
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
-
Schopfer, F.J., Lin, Y., Baker, P.R., Cui, T., Garcia-Barrio, M., Zhang, J., Chen, K., Chen, Y.E., and Freeman, B.A.: Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor γ ligand. Proc. Natl. Acad. Sci. USA, 102, 2340-2345, 2005.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2340-2345
-
-
Schopfer, F.J.1
Lin, Y.2
Baker, P.R.3
Cui, T.4
Garcia-Barrio, M.5
Zhang, J.6
Chen, K.7
Chen, Y.E.8
Freeman, B.A.9
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