Recent insights into the cell biology of bladder smooth muscle

Nephron - Experimental Nephrology

Volumn 102, Issue 1, 2006, Pages

  Adam, Rosalyn M ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Growth factors; Phenotypic modulation; Signal transduction; Smooth muscle

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ARGINYLGLYCYLASPARTIC ACID; CYCLOSPORIN A; DOXAZOSIN; GADOLINIUM CHLORIDE; GEFITINIB; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMATINIB; MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; NIFEDIPINE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TACROLIMUS; TRASTUZUMAB; VERAPAMIL;

BLADDER DISEASE; BLADDER MUSCLE; BLADDER NECK STENOSIS; CANCER; CANCER CHEMOTHERAPY; CLINICAL TRIAL; CYTOLOGY; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG TARGETING; HUMAN; HYPERTROPHY; MEDICAL RESEARCH; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; TISSUE EXPANSION; URETHRA; URINARY TRACT;

ANIMALS; CELL PHYSIOLOGY; HUMANS; MUSCLE, SMOOTH; URINARY BLADDER;

EID: 32844459142     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000088310     Document Type: Short Survey

References (35)

1. Iqbal J, Zaidi M: Molecular regulation of mechanotransduction. Biochem Biophys Res Commun 2005;328:751-755.
2. Yamaguchi O: Response of bladder smooth muscle cells to obstruction: signal transduction and the role of mechanosensors. Urology 2004;63:11-16.
3. Adam RM, Roth JA, Cheng HL, Rice DC, Khoury J, Bauer SB, Peters CA, Freeman MR: Signaling through PI3K/Akt mediates stretch and PDGF-BB-dependent DNA synthesis in bladder smooth muscle cells. J Urol 2003;169:2388-2393.
4. Tamura I, Rosenbloom J, Macarak E, Chaqour B: Regulation of Cyr61 gene expression by mechanical stretch through multiple signaling pathways. Am J Physiol Cell Physiol 2001;281:C1524-C1532.
5. Adam RM, Eaton SH, Estrada C, Nimgaonkar A, Shih SC, Smith LE, Kohane IS, Bagli D, Freeman MR: Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol Genomics 2004;20:36-44.
6. Nguyen HT, Adam RM, Bride SH, Park JM, Peters CA, Freeman MR: Cyclic stretch activates p38 SAPK2-, ErbB2-, and AT1-dependent signaling in bladder smooth muscle cells. Am J Physiol Cell Physiol 2000;279:C1155-C1167.
7. Stehr M, Adam RM, Khoury J, Zhuang L, Solomon KR, Peters CA, Freeman MR: Platelet derived growth factor-BB is a potent mitogen for rat ureteral and human bladder smooth muscle cells: dependence on lipid rafts for cell signaling. J Urol 2003;169:1165-1170.
8. Hu Y, Bock G, Wick G, Xu Q: Activation of PDGF receptor alpha in vascular smooth muscle cells by mechanical stress. FASEB J 1998;12:1135-1142.
9. Fischer OM, Streit S, Hart S, Ullrich A: Beyond Herceptin and Gleevec. Curr Opin Chem Biol 2003;7:490-495.
10. Kubota Y, Kajioka S, Biers SM, Yokota E, Kohri K, Brading AF: Investigation of the effect of the c-kit inhibitor Glivec on isolated guinea-pig detrusor preparations. Auton Neurosci 2004;115:64-73.
11. Riento K, Ridley AJ: ROCKS: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 2003;4:446-456.
12. Wibberley A, Chen Z, Hu E, Hieble JP, Westfall TD: Expression and functional role of Rho kinase in rat urinary bladder smooth muscle. Br J Pharmacol 2003;138:757-766.
13. Bing W, Chang S, Hypolite JA, DiSanto ME, Zderic SA, Rolf L, Wein AJ, Chacko S: Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase. Am J Physiol Renal Physiol 2003;285:F990-F997.
14. Johansson R, Persson K: Phenotypic modulation of cultured bladder smooth muscle cells and the expression of inducible nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 2004;286:R642-R648.
15. Yoshida T, Sinha S, Dandre F, Wamhoff BR, Hoofnagle MH, Kremer BE, Wang DZ, Olson EN, Owens GK: Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ Res 2003;92:856-864.
16. Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, Tamakawa H, Yamagami K, Inui J, Maekawa M, Narumiya S: Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997;389:990-994.
17. Rees RW, Foxwell NA, Ralph DJ, Kell PD, Moncada S, Cellek S: Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells. J Urol 2003;170:2517-2522.
18. Austin PF, Cook BL, Niederhoff RA, Manson SR, Coplen DE, Weintraub SJ: Inhibition of mitogenic signaling and induction of apoptosis in human bladder smooth muscle cells treated with doxazosin. J Urol 2004;172:1662-1665.
19. Benning CM, Kyprianou N: Quinazoline-derived alpha-1-adrenoceptor antagonists induce prostate cancer cell apoptosis via an alpha-1-adrenoceptor- independent action. Cancer Res 2002;62:597-602.
20. 2+;in JNK activation by mechanical stretch in bladder smooth muscle cells. Am J Physiol Cell Physiol 2001;281:C1165-C1172.
21. Nozaki K, Tomizawa K, Yokoyama T, Kumon H, Matsui H: Calcineurin mediates bladder smooth muscle hypertrophy after bladder outlet obstruction. J Urol 2003;170:2077-2081.
22. Stothers L, Laher I, Christ GT: A review of the L-arginine-nitric oxide-guanylate cyclase pathway as a mediator of lower urinary tract physiology and symptoms. Can J Urol 2003;10:1971-1980.
23. Johansson RK, Poljakovic M, Andersson KE, Persson K: Expression of nitric oxide synthase in bladder smooth muscle cells: regulation by cytokines and L-arginine. J Urol 2002;168:2280-2285.
24. Johansson R, Pandita RK Poljakovic M, Garcia-Pascual A, De Vente J, Persson K: Activity and expression of nitric oxide synthase in the hypertrophied rat bladder and the effect of nitric oxide on bladder smooth muscle growth. J Urol 2002;168:2689-2694.
25. Felsen D, Dardashti K, Ostad M, Lemer ML, Gross SS, Chen J, Vaughan ED Jr, Poppas DP: Inducible nitric oxide synthase promotes pathophysiological consequences of experimental bladder outlet obstruction. J Urol 2003;169:1569-1572.
26. Upadhyay J, Aitken KJ, Damdar C, Bolduc S, Bagli DJ: Integrins expressed with bladder extracellular matrix after stretch injury in vivo mediate bladder smooth muscle cell growth in vitro. J Urol 2003;169:750-755.
27. Here DB, Aitken K, Bagli DJ: Collagen directly stimulates bladder smooth muscle cell growth in vitro: regulation by extracellular regulated mitogen activated protein kinase. J Urol 2003;170:2072-2076.
28. Matsuno H, Stassen JM, Vermylen J, Deckmyn H: Inhibition of integrin function by a cyclic RGD-containing peptide prevents neointima formation. Circulation 1994;90:2203-2206.
29. Roy J, Kazi M, Hedin U, Thyberg J: Phenotypic modulation of arterial smooth muscle cells is associated with prolonged activation of ERK1/2. Differentiation 2001;67:50-58.
30. Matsuno H, Ishisaki A, Nakajima K, Kozawa O: Effect of a synthetic matrix metalloproteinase inhibitor (ONO-4817) on neointima formation in hypercholesterolemic hamsters. J Cardiovasc Pharmacol 2004;44:57-65.
31. Woodman SE, Cheung MW, Tarr M, North AC, Schubert W, Lagaud G, Marks CB, Russell RG, Hassan GS, Factor SM, Christ GJ, Lisanti MP: Urogenital alterations in aged male caveolin-1 knockout mice. J Urol 2004;171:950-957.
32. Stehr M, Estrada CR, Khoury J, Danciu TE, Sullivan MP, Peters CA, Solomon KR, Freeman MR, Adam RM: Caveolae are negative regulators of transforming growth factor-beta 1 signaling in ureteral smooth muscle cells. J Urol 2004;172:2451-2455.
33. Simons K, Toomre D: Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 2000;1:31-39.
34. Hirai A, Nakamura S, Noguchi Y, Yasuda T, Kitagawa M, Tatsuno I, Oeda T, Tahara K, Terano T, Narumiya S, Kohn LD, Saito Y: Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. J Biol Chem 1997;272:13-16.
35. Takemoto M, Liao JK: Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 2001;21:1712-1719.