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Volumn 170, Issue 6 I, 2003, Pages 2517-2522

Y-27632, A Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells

Author keywords

Muscle, smooth; Prostate; Prostatic hyperplasia; Rats, Wistar; Rho associated kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PHENYLEPHRINE; PHOSPHOTRANSFERASE INHIBITOR; RHO KINASE;

EID: 0242608409     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000085024.47406.6c     Document Type: Article
Times cited : (95)

References (31)
  • 1
    • 0029684668 scopus 로고    scopus 로고
    • Benign prostatic hyperplasia: A review of its histogenesis and natural history
    • Oesterling, J. E.: Benign prostatic hyperplasia: a review of its histogenesis and natural history. Prostate, suppl., 6: 67, 1996
    • (1996) Prostate, Suppl , vol.6 , pp. 67
    • Oesterling, J.E.1
  • 2
    • 0021149603 scopus 로고
    • The development of human benign prostatic hyperplasia with age
    • Berry, S. J., Coffey, D. S., Walsh, P. C. and Ewing, L. L.: The development of human benign prostatic hyperplasia with age. J Urol, 132: 474, 1984
    • (1984) J Urol , vol.132 , pp. 474
    • Berry, S.J.1    Coffey, D.S.2    Walsh, P.C.3    Ewing, L.L.4
  • 3
    • 0024214094 scopus 로고
    • Alpha-adrenergic mechanisms in dynamics of benign prostatic hypertrophy
    • Caine, M.: Alpha-adrenergic mechanisms in dynamics of benign prostatic hypertrophy. Urology, 32: 16, 1988
    • (1988) Urology , vol.32 , pp. 16
    • Caine, M.1
  • 4
    • 0000106241 scopus 로고    scopus 로고
    • Combination medical therapy for symptomatic benign prostatic hyperplasia
    • Savage, S. J., Spungen, A. M., Galea, G., Britanico, J. and Vapnek, J. M.: Combination medical therapy for symptomatic benign prostatic hyperplasia. Can J Urol, 5: 578, 1998
    • (1998) Can J Urol , vol.5 , pp. 578
    • Savage, S.J.1    Spungen, A.M.2    Galea, G.3    Britanico, J.4    Vapnek, J.M.5
  • 5
    • 0035134750 scopus 로고    scopus 로고
    • Combined effect of terazosin and finasteride on apoptosis cell proliferation, and transforming growth factor-beta expression in benign prostatic hyperplasia
    • Glasman, D. T., Chon, J. K., Borkowski, A., Jacobs, S. C. and Kyprianou, N.: Combined effect of terazosin and finasteride on apoptosis, cell proliferation, and transforming growth factor-beta expression in benign prostatic hyperplasia. Prostate, 46: 45, 2001
    • (2001) Prostate , vol.46 , pp. 45
    • Glasman, D.T.1    Chon, J.K.2    Borkowski, A.3    Jacobs, S.C.4    Kyprianou, N.5
  • 6
    • 0034650714 scopus 로고    scopus 로고
    • Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
    • Somlyo, A. P. and Somlyo, A. V.: Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol, 522: 177, 2000
    • (2000) J Physiol , vol.522 , pp. 177
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 7
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata, M., Ishizaki, T., Satoh, H., Ono, T., Kawahara, T., Morishita, T. et al: Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature, 389: 990, 1997
    • (1997) Nature , vol.389 , pp. 990
    • Uehata, M.1    Ishizaki, T.2    Satoh, H.3    Ono, T.4    Kawahara, T.5    Morishita, T.6
  • 8
    • 0033802864 scopus 로고    scopus 로고
    • Activation of Rho signaling contributes to lysophosphatidic acid-induced contraction of intact ileal smooth muscle of guinea-pig
    • Mori, M. and Tsushima, H.: Activation of Rho signaling contributes to lysophosphatidic acid-induced contraction of intact ileal smooth muscle of guinea-pig. Can J Physiol Pharmacol, 78: 729, 2000
    • (2000) Can J Physiol Pharmacol , vol.78 , pp. 729
    • Mori, M.1    Tsushima, H.2
  • 9
    • 0036850455 scopus 로고    scopus 로고
    • A Rho-kinase inhibitor, soluble guanylate cyclase activator and nitric oxide-releasing PDE5 inhibitor: Novel approaches to erectile dysfunction
    • Cellek, S., Rees, R. W. and Kalsi, J. A.: A Rho-kinase inhibitor, soluble guanylate cyclase activator and nitric oxide-releasing PDE5 inhibitor: novel approaches to erectile dysfunction. Expert Opin Investig Drugs, 11: 1563, 2002
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 1563
    • Cellek, S.1    Rees, R.W.2    Kalsi, J.A.3
  • 11
    • 0034955766 scopus 로고    scopus 로고
    • Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum
    • Rees, R. W., Ralph, D. J., Royle, M., Moncada, S. and Cellek, S.: Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum. Br J Pharmacol, 133: 455, 2001
    • (2001) Br J Pharmacol , vol.133 , pp. 455
    • Rees, R.W.1    Ralph, D.J.2    Royle, M.3    Moncada, S.4    Cellek, S.5
  • 12
    • 0035134310 scopus 로고    scopus 로고
    • Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway
    • Chitaley, K., Wingard, C. J., Clinton Webb, R., Branam, H., Stopper, V. S., Lewis, R. W. et al: Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway. Nat Med, 7: 119, 2001
    • (2001) Nat Med , vol.7 , pp. 119
    • Chitaley, K.1    Wingard, C.J.2    Clinton Webb, R.3    Branam, H.4    Stopper, V.S.5    Lewis, R.W.6
  • 13
    • 0035827716 scopus 로고    scopus 로고
    • Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase
    • Sauzeau, V., Le Mellionnec, E., Bertoglio, J., Scalbert, E., Pacaud, P. and Loirand, G.: Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circ Res, 88: 1102, 2001
    • (2001) Circ Res , vol.88 , pp. 1102
    • Sauzeau, V.1    Le Mellionnec, E.2    Bertoglio, J.3    Scalbert, E.4    Pacaud, P.5    Loirand, G.6
  • 14
    • 0033612371 scopus 로고    scopus 로고
    • Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
    • Seasholtz, T. M., Majumdar, M., Kaplan, D. D. and Brown, J. H.: Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Circ Res, 84: 1186, 1999
    • (1999) Circ Res , vol.84 , pp. 1186
    • Seasholtz, T.M.1    Majumdar, M.2    Kaplan, D.D.3    Brown, J.H.4
  • 15
    • 0035895335 scopus 로고    scopus 로고
    • Role of Rho-associated kinase in neointima formation after vascular injury
    • Shibata, R., Kai, H., Seki, Y., Kato, S., Morimatsu, M., Kaibuchi, K. et al: Role of Rho-associated kinase in neointima formation after vascular injury. Circulation, 103: 284, 2001
    • (2001) Circulation , vol.103 , pp. 284
    • Shibata, R.1    Kai, H.2    Seki, Y.3    Kato, S.4    Morimatsu, M.5    Kaibuchi, K.6
  • 16
    • 0031759413 scopus 로고    scopus 로고
    • Videoimaging of prostatic stromal-cell contraction: An in vitro model for studying drug effects
    • Corvin, S., Bosch, S. T., Eder, I., Thurnher, M., Bartsch, G. and Klocker, H.: Videoimaging of prostatic stromal-cell contraction: an in vitro model for studying drug effects. Prostate, 37: 209, 1998
    • (1998) Prostate , vol.37 , pp. 209
    • Corvin, S.1    Bosch, S.T.2    Eder, I.3    Thurnher, M.4    Bartsch, G.5    Klocker, H.6
  • 18
    • 0025695687 scopus 로고
    • Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: An insight into endotoxin shock
    • Rees, D. D., Cellek, S., Palmer, R. M. and Moncada, S.: Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: an insight into endotoxin shock. Biochem Biophys Res Commun, 173: 541, 1990
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 541
    • Rees, D.D.1    Cellek, S.2    Palmer, R.M.3    Moncada, S.4
  • 19
    • 0018432411 scopus 로고
    • Prostaglandins and tetrodotoxin-insensitive relaxation of opossum lower esophageal sphincter
    • Daniel, E. E., Crankshaw, J. and Sarna, S.: Prostaglandins and tetrodotoxin-insensitive relaxation of opossum lower esophageal sphincter. Am J Physiol, 236: E153, 1979
    • (1979) Am J Physiol , vol.236
    • Daniel, E.E.1    Crankshaw, J.2    Sarna, S.3
  • 21
    • 0033603660 scopus 로고    scopus 로고
    • Cellular redistribution of PKCalpha, rhoA, and ROKalpha following smooth muscle agonist stimulation
    • Taggart, M. J., Lee, Y. H. and Morgan, K. G.: Cellular redistribution of PKCalpha, rhoA, and ROKalpha following smooth muscle agonist stimulation. Exp Cell Res, 251: 92, 1999
    • (1999) Exp Cell Res , vol.251 , pp. 92
    • Taggart, M.J.1    Lee, Y.H.2    Morgan, K.G.3
  • 22
    • 0032537819 scopus 로고    scopus 로고
    • Signals from Ras and Rho GTPases interact to regulate expression of P21Waf1/Cip1
    • Olson, M. F., Paterson, H. F. and Marshall, C. J.: Signals from Ras and Rho GTPases interact to regulate expression of P21Waf1/Cip1. Nature, 394: 295, 1998
    • (1998) Nature , vol.394 , pp. 295
    • Olson, M.F.1    Paterson, H.F.2    Marshall, C.J.3
  • 23
    • 0242407997 scopus 로고    scopus 로고
    • Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum
    • Sward, K., Dreja, K., Susnjar, M., Hellstrand, P., Hartshorne, D. J. and Walsh, M. P.: Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum. J Physiol, 522: 33, 2000
    • (2000) J Physiol , vol.522 , pp. 33
    • Sward, K.1    Dreja, K.2    Susnjar, M.3    Hellstrand, P.4    Hartshorne, D.J.5    Walsh, M.P.6
  • 24
    • 0033143779 scopus 로고    scopus 로고
    • Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization
    • Yoshii, A., Iizuka, K., Dobashi, K., Horie, T., Harada, T., Nakazawa, T. et al: Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization. Am J Respir Cell Mol Biol, 20: 1190, 1999
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 1190
    • Yoshii, A.1    Iizuka, K.2    Dobashi, K.3    Horie, T.4    Harada, T.5    Nakazawa, T.6
  • 25
    • 0034581716 scopus 로고    scopus 로고
    • The autonomic and sensory innervation of the smooth muscle of the prostate gland: A review of pharmacological and histological studies
    • Pennefather, J. N., Lau, W. A., Mitchelson, F. and Ventura, S.: The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies. J Auton Pharmacol, 20: 193, 2000
    • (2000) J Auton Pharmacol , vol.20 , pp. 193
    • Pennefather, J.N.1    Lau, W.A.2    Mitchelson, F.3    Ventura, S.4
  • 26
    • 0036154042 scopus 로고    scopus 로고
    • Evidence for activation of the reninangiotensin system in the human prostate: Increased angiotensin II and reduced AT(1) receptor expression in benign prostatic hyperplasia
    • Dinh, D. T., Frauman, A. G., Somers, G. R., Ohishi, M., Zhou, J., Casley, D. J. et al: Evidence for activation of the reninangiotensin system in the human prostate: increased angiotensin II and reduced AT(1) receptor expression in benign prostatic hyperplasia. J Pathol, 196: 213, 2002
    • (2002) J Pathol , vol.196 , pp. 213
    • Dinh, D.T.1    Frauman, A.G.2    Somers, G.R.3    Ohishi, M.4    Zhou, J.5    Casley, D.J.6
  • 27
    • 0032828697 scopus 로고    scopus 로고
    • A quantitative study of atropine-resistant contractile responses in human detrusor smooth muscle, from stable, unstable and obstructed bladders
    • Bayliss, M., Wu, C., Newgreen, D., Mundy, A. R. and Fry, C. H.: A quantitative study of atropine-resistant contractile responses in human detrusor smooth muscle, from stable, unstable and obstructed bladders. J Urol, 162: 1833, 1999
    • (1999) J Urol , vol.162 , pp. 1833
    • Bayliss, M.1    Wu, C.2    Newgreen, D.3    Mundy, A.R.4    Fry, C.H.5
  • 28
    • 0037352327 scopus 로고    scopus 로고
    • Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle
    • Wibberley, A., Chen, Z., Hu, E., Hieble, J. P. and Westfall, T. D.: Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol, 138: 757, 2003
    • (2003) Br J Pharmacol , vol.138 , pp. 757
    • Wibberley, A.1    Chen, Z.2    Hu, E.3    Hieble, J.P.4    Westfall, T.D.5
  • 29
    • 0034949355 scopus 로고    scopus 로고
    • Mechanisms of endothelin-1-induced potentiation of noradrenaline response in rat mesenteric artery
    • Matsumura, Y., Kita, S. and Okui, T.: Mechanisms of endothelin-1-induced potentiation of noradrenaline response in rat mesenteric artery. Clin Exp Pharmacol Physiol, 28: 540, 2001
    • (2001) Clin Exp Pharmacol Physiol , vol.28 , pp. 540
    • Matsumura, Y.1    Kita, S.2    Okui, T.3
  • 30
    • 0034284368 scopus 로고    scopus 로고
    • The contractile effects of endothelins on the smooth muscle of the rat prostate gland
    • Salamoussa, A., Lau, W. A., Pennefather, J. N. and Ventura, S.: The contractile effects of endothelins on the smooth muscle of the rat prostate gland. Eur J Pharmacol, 403: 139, 2000
    • (2000) Eur J Pharmacol , vol.403 , pp. 139
    • Salamoussa, A.1    Lau, W.A.2    Pennefather, J.N.3    Ventura, S.4
  • 31
    • 0035572885 scopus 로고    scopus 로고
    • Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries
    • Matrougui, K., Tanko, L. B., Loufrani, L., Gorny, D., Levy, B. I., Tedgui, A. et al: Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries. Arterioscler Thromb Vasc Biol, 21: 1288, 2001
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1288
    • Matrougui, K.1    Tanko, L.B.2    Loufrani, L.3    Gorny, D.4    Levy, B.I.5    Tedgui, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.