Signaling through P13K/AKT mediates stretch and PDGF-BBdependent DNA synthesis in bladder smooth muscle cells

Journal of Urology

Volumn 169, Issue 6, 2003, Pages 2388-2393

  Adam, Rosalyn M ^a   Roth, Jonathan A ^b   Cheng, Hong Lin ^c   Rice, Dana C ^c   Khoury, Joseph ^c   Bauer, Stuart B ^c   Peters, Craig A ^c   Freeman, Michael R ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF VIRGINIA MEDICAL CENTER   (United States)

^c NONE

Author keywords

Mechanical; Platelet derived growth factor; Protein serine threonine kinases; Stress

Indexed keywords

ANTIBODY; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; SYNAPTOPHYSIN; THYMIDINE; UNCLASSIFIED DRUG; AKT1 PROTEIN, RAT; DNA; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; ONCOPROTEIN; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR BB; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; BLADDER MUSCLE; CELL HYPERPLASIA; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MECHANICAL STRESS; MUSCLE STRETCHING; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; BLADDER; CARDIOMEGALY; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; HEART MUSCLE; HYPERTROPHY; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SMOOTH MUSCLE; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARDIOMEGALY; CELLS, CULTURED; DNA; ENZYME ACTIVATION; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HYPERTROPHY; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; UP-REGULATION; URINARY BLADDER;

EID: 0037949107     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000063980.99368.35     Document Type: Article

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