Truncation of the C-terminus of human MLH1 blocks intracellular stabilization of PMS2 and disrupts DNA mismatch repair

DNA Repair

Volumn 5, Issue 3, 2006, Pages 347-361

  Mohd, Azizah B ^a   Palama, Brett ^a   Nelson, Scott E ^a   Tomer, Guy ^b,c   Nguyen, Megan ^b   Huo, Xin ^a   Buermeyer, Andrew B ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c SHEBA MEDICAL CENTER   (Israel)

Author keywords

DNA mismatch repair; Heterodimer interaction; MLH1; PMS2

Indexed keywords

DNA; HETERODIMER; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; TIOGUANINE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOTOXICITY; FIBROBLAST; MISMATCH REPAIR; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STABILITY; STEADY STATE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; BASE PAIR MISMATCH; CARRIER PROTEINS; DNA REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EMBRYO; FIBROBLASTS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUPPRESSION, GENETIC; THIOGUANINE;

ANIMALIA; EUKARYOTA; MAMMALIA;

EID: 32644459732     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2005.11.001     Document Type: Article

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