-
2
-
-
0040992183
-
Synthesis, bacterial expression, and mutagenesis of the gene coding for mammalian cytochrome b5
-
S. Beck von Bodman, M.A. Schuler, D.R. Jollie, and S.G. Sligar Synthesis, bacterial expression, and mutagenesis of the gene coding for mammalian cytochrome b5 Proc. Natl. Acad. Sci. USA 83 1986 9443 9447
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 9443-9447
-
-
Beck Von Bodman, S.1
Schuler, M.A.2
Jollie, D.R.3
Sligar, S.G.4
-
3
-
-
0348111398
-
The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2
-
E. Bourdon, D.K. Kang, M.C. Ghosh, S.K. Drake, J. Wey, R.L. Levine, and T.A. Rouault The role of endogenous heme synthesis and degradation domain cysteines in cellular iron-dependent degradation of IRP2 Blood Cells Mol. Dis. 31 2003 247 255
-
(2003)
Blood Cells Mol. Dis.
, vol.31
, pp. 247-255
-
-
Bourdon, E.1
Kang, D.K.2
Ghosh, M.C.3
Drake, S.K.4
Wey, J.5
Levine, R.L.6
Rouault, T.A.7
-
4
-
-
0025965045
-
Amino acid microsequencing of internal tryptic peptides of heme-regulated eukaryotic initiation factor 2 α subunit kinase: Homology to protein kinases
-
J.J. Chen, J.K. Pal, R. Petryshyn, I. Kuo, J.M. Yang, M.S. Throop, L. Gehrke, and I.M. London Amino acid microsequencing of internal tryptic peptides of heme-regulated eukaryotic initiation factor 2 α subunit kinase: homology to protein kinases Proc. Natl. Acad. Sci. USA 88 1991 315 319
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 315-319
-
-
Chen, J.J.1
Pal, J.K.2
Petryshyn, R.3
Kuo, I.4
Yang, J.M.5
Throop, M.S.6
Gehrke, L.7
London, I.M.8
-
5
-
-
0027198563
-
Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor
-
P. Chen, P. Johnson, T. Sommer, S. Jentsch, and M. Hochstrasser Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor Cell 74 1993 357 369
-
(1993)
Cell
, vol.74
, pp. 357-369
-
-
Chen, P.1
Johnson, P.2
Sommer, T.3
Jentsch, S.4
Hochstrasser, M.5
-
6
-
-
0014217153
-
The interaction of nucleotides with the active site of staphylococcal nuclease. Spectrophotometric studies
-
P. Cuatrecasas, S. Fuchs, and C.B. Anfinsen The interaction of nucleotides with the active site of staphylococcal nuclease. Spectrophotometric studies J. Biol. Chem. 242 1967 4759 4767
-
(1967)
J. Biol. Chem.
, vol.242
, pp. 4759-4767
-
-
Cuatrecasas, P.1
Fuchs, S.2
Anfinsen, C.B.3
-
7
-
-
0021070823
-
The diverse spectroscopic properties of ferrous cytochrome P-450-CAM ligand complexes
-
J.H. Dawson, L.A. Andersson, and M. Sono The diverse spectroscopic properties of ferrous cytochrome P-450-CAM ligand complexes J. Biol. Chem. 258 1983 13637 13645
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 13637-13645
-
-
Dawson, J.H.1
Andersson, L.A.2
Sono, M.3
-
8
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
M.H. Glickman, and A. Ciechanover The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol. Rev. 82 2002 373 428
-
(2002)
Physiol. Rev.
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
9
-
-
0032524657
-
Involvement of heme in the degradation of iron-regulatory protein 2
-
L.S. Goessling, D.P. Mascotti, and R.E. Thach Involvement of heme in the degradation of iron-regulatory protein 2 J. Biol. Chem. 273 1998 12555 12557
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12555-12557
-
-
Goessling, L.S.1
Mascotti, D.P.2
Thach, R.E.3
-
10
-
-
0028982262
-
Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome
-
B. Guo, J.D. Phillips, Y. Yu, and E.A. Leibold Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome J. Biol. Chem. 270 1995 21645 21651
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21645-21651
-
-
Guo, B.1
Phillips, J.D.2
Yu, Y.3
Leibold, E.A.4
-
11
-
-
0141890273
-
Oxygen and iron regulation of iron regulatory protein 2
-
E.S. Hanson, M.L. Rawlins, and E.A. Leibold Oxygen and iron regulation of iron regulatory protein 2 J. Biol. Chem. 278 2003 40337 40342
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40337-40342
-
-
Hanson, E.S.1
Rawlins, M.L.2
Leibold, E.A.3
-
12
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
M.W. Hentze, M.U. Muckenthaler, and N.C. Andrews Balancing acts: molecular control of mammalian iron metabolism Cell 117 2004 285 297
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
13
-
-
0028788316
-
Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2
-
K. Iwai, R.D. Klausner, and T.A. Rouault Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2 EMBO J. 14 1995 5350 5357
-
(1995)
EMBO J.
, vol.14
, pp. 5350-5357
-
-
Iwai, K.1
Klausner, R.D.2
Rouault, T.A.3
-
14
-
-
0032574765
-
Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins
-
K. Iwai, S.K. Drake, N.B. Wehr, A.M. Weissman, T. LaVaute, N. Minato, R.D. Klausner, R.L. Levine, and T.A. Rouault Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins Proc. Natl. Acad. Sci. USA 95 1998 4924 4928
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4924-4928
-
-
Iwai, K.1
Drake, S.K.2
Wehr, N.B.3
Weissman, A.M.4
Lavaute, T.5
Minato, N.6
Klausner, R.D.7
Levine, R.L.8
Rouault, T.A.9
-
15
-
-
8544244946
-
Identification of a heme-sensing domain in iron regulatory protein 2
-
J. Jeong, T.A. Rouault, and R.L. Levine Identification of a heme-sensing domain in iron regulatory protein 2 J. Biol. Chem. 279 2004 45450 45454
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45450-45454
-
-
Jeong, J.1
Rouault, T.A.2
Levine, R.L.3
-
16
-
-
0038013736
-
Iron regulatory protein 2 as iron sensor. Iron-dependent oxidative modification of cysteine
-
D.K. Kang, J. Jeong, S.K. Drake, N.B. Wehr, T.A. Rouault, and R.L. Levine Iron regulatory protein 2 as iron sensor. Iron-dependent oxidative modification of cysteine J. Biol. Chem. 278 2003 14857 14864
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14857-14864
-
-
Kang, D.K.1
Jeong, J.2
Drake, S.K.3
Wehr, N.B.4
Rouault, T.A.5
Levine, R.L.6
-
17
-
-
0347624596
-
S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway
-
S. Kim, S.S. Wing, and P. Ponka S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway Mol. Cell. Biol. 24 2004 330 337
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 330-337
-
-
Kim, S.1
Wing, S.S.2
Ponka, P.3
-
18
-
-
0027405813
-
Regulation by heme of mitochondrial protein transport through a conserved amino acid motif
-
J.T. Lathrop, and M.P. Timko Regulation by heme of mitochondrial protein transport through a conserved amino acid motif Science 259 1993 522 525
-
(1993)
Science
, vol.259
, pp. 522-525
-
-
Lathrop, J.T.1
Timko, M.P.2
-
20
-
-
10744223491
-
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
-
E.G. Meyron-Holtz, M.C. Ghosh, K. Iwai, T. LaVaute, X. Brazzolotto, U.V. Berger, W. Land, H. Ollivierre-Wilson, A. Grinberg, and P. Love Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis EMBO J. 23 2004 386 395
-
(2004)
EMBO J.
, vol.23
, pp. 386-395
-
-
Meyron-Holtz, E.G.1
Ghosh, M.C.2
Iwai, K.3
Lavaute, T.4
Brazzolotto, X.5
Berger, U.V.6
Land, W.7
Ollivierre-Wilson, H.8
Grinberg, A.9
Love, P.10
-
21
-
-
10844282789
-
Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo
-
E.G. Meyron-Holtz, M.C. Ghosh, and T.A. Rouault Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo Science 306 2004 2087 2090
-
(2004)
Science
, vol.306
, pp. 2087-2090
-
-
Meyron-Holtz, E.G.1
Ghosh, M.C.2
Rouault, T.A.3
-
22
-
-
4644371570
-
Role of the heme regulatory motif in the heme-mediated inhibition of mitochondrial import of 5-aminolevulinate synthase
-
H. Munakata, J.Y. Sun, K. Yoshida, T. Nakatani, E. Honda, S. Hayakawa, K. Furuyama, and N. Hayashi Role of the heme regulatory motif in the heme-mediated inhibition of mitochondrial import of 5-aminolevulinate synthase J. Biochem. (Tokyo) 136 2004 233 238
-
(2004)
J. Biochem. (Tokyo)
, vol.136
, pp. 233-238
-
-
Munakata, H.1
Sun, J.Y.2
Yoshida, K.3
Nakatani, T.4
Honda, E.5
Hayakawa, S.6
Furuyama, K.7
Hayashi, N.8
-
23
-
-
17944372665
-
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1
-
K. Ogawa, J. Sun, S. Taketani, O. Nakajima, C. Nishitani, S. Sassa, N. Hayashi, M. Yamamoto, S. Shibahara, H. Fujita, and K. Igarashi Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1 EMBO J. 20 2001 2835 2843
-
(2001)
EMBO J.
, vol.20
, pp. 2835-2843
-
-
Ogawa, K.1
Sun, J.2
Taketani, S.3
Nakajima, O.4
Nishitani, C.5
Sassa, S.6
Hayashi, N.7
Yamamoto, M.8
Shibahara, S.9
Fujita, H.10
Igarashi, K.11
-
24
-
-
0024979286
-
Functional dissection and sequence of yeast HAP1 activator
-
K. Pfeifer, K.S. Kim, S. Kogan, and L. Guarente Functional dissection and sequence of yeast HAP1 activator Cell 56 1989 291 301
-
(1989)
Cell
, vol.56
, pp. 291-301
-
-
Pfeifer, K.1
Kim, K.S.2
Kogan, S.3
Guarente, L.4
-
25
-
-
0036161801
-
Interaction between the bacterial iron response regulator and ferrochelatase mediates genetic control of heme biosynthesis
-
Z. Qi, and M.R. O'Brian Interaction between the bacterial iron response regulator and ferrochelatase mediates genetic control of heme biosynthesis Mol. Cell 9 2002 155 162
-
(2002)
Mol. Cell
, vol.9
, pp. 155-162
-
-
Qi, Z.1
O'Brian, M.R.2
-
26
-
-
0033539642
-
Heme is an effector molecule for iron-dependent degradation of the bacterial iron response regulator (Irr) protein
-
Z. Qi, I. Hamza, and M.R. O'Brian Heme is an effector molecule for iron-dependent degradation of the bacterial iron response regulator (Irr) protein Proc. Natl. Acad. Sci. USA 96 1999 13056 13061
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13056-13061
-
-
Qi, Z.1
Hamza, I.2
O'Brian, M.R.3
-
27
-
-
0026927996
-
An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein
-
T.A. Rouault, D.J. Haile, W.E. Downey, C.C. Philpott, C. Tang, F. Samaniego, J. Chin, I. Paul, D. Orloff, and J.B. Harford An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein Biometals 5 1992 131 140
-
(1992)
Biometals
, vol.5
, pp. 131-140
-
-
Rouault, T.A.1
Haile, D.J.2
Downey, W.E.3
Philpott, C.C.4
Tang, C.5
Samaniego, F.6
Chin, J.7
Paul, I.8
Orloff, D.9
Harford, J.B.10
-
28
-
-
0028143071
-
Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation
-
F. Samaniego, J. Chin, K. Iwai, T.A. Rouault, and R.D. Klausner Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation J. Biol. Chem. 269 1994 30904 30910
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30904-30910
-
-
Samaniego, F.1
Chin, J.2
Iwai, K.3
Rouault, T.A.4
Klausner, R.D.5
-
29
-
-
0037352408
-
Haemin uptake and use as an iron source by Candida albicans: Role of CaHMX1-encoded haem oxygenase
-
R. Santos, N. Buisson, S. Knight, A. Dancis, J.M. Camadro, and E. Lesuisse Haemin uptake and use as an iron source by Candida albicans: role of CaHMX1-encoded haem oxygenase Microbiol. 149 2003 579 588
-
(2003)
Microbiol.
, vol.149
, pp. 579-588
-
-
Santos, R.1
Buisson, N.2
Knight, S.3
Dancis, A.4
Camadro, J.M.5
Lesuisse, E.6
-
30
-
-
4544220638
-
Why heme needs to be degraded to iron, biliverdin IXα, and carbon monoxide?
-
S. Sassa Why heme needs to be degraded to iron, biliverdin IXα, and carbon monoxide? Antioxid. Redox Signal. 6 2004 819 824
-
(2004)
Antioxid. Redox Signal.
, vol.6
, pp. 819-824
-
-
Sassa, S.1
-
31
-
-
0017367091
-
Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process
-
S. Sassa, and A. Kappas Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process J. Biol. Chem. 252 1977 2428 2436
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 2428-2436
-
-
Sassa, S.1
Kappas, A.2
-
32
-
-
3342905184
-
Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1
-
H. Suzuki, S. Tashiro, S. Hira, J. Sun, C. Yamazaki, Y. Zenke, M. Ikeda-Saito, M. Yoshida, and K. Igarashi Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1 EMBO J. 23 2004 2544 2553
-
(2004)
EMBO J.
, vol.23
, pp. 2544-2553
-
-
Suzuki, H.1
Tashiro, S.2
Hira, S.3
Sun, J.4
Yamazaki, C.5
Zenke, Y.6
Ikeda-Saito, M.7
Yoshida, M.8
Igarashi, K.9
-
33
-
-
0025203672
-
Molecular cloning, sequencing, and expression of mouse ferrochelatase
-
S. Taketani, Y. Nakahashi, T. Osumi, and R. Tokunaga Molecular cloning, sequencing, and expression of mouse ferrochelatase J. Biol. Chem. 265 1990 19377 19380
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 19377-19380
-
-
Taketani, S.1
Nakahashi, Y.2
Osumi, T.3
Tokunaga, R.4
-
34
-
-
0032566713
-
Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity
-
S. Taoka, S. Ohja, X. Shan, W.D. Kruger, and R. Banerjee Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity J. Biol. Chem. 273 1998 25179 25184
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25179-25184
-
-
Taoka, S.1
Ohja, S.2
Shan, X.3
Kruger, W.D.4
Banerjee, R.5
-
35
-
-
0347991814
-
Histidine and lysine as targets of oxidative modification
-
K. Uchida Histidine and lysine as targets of oxidative modification Amino Acids 25 2003 249 257
-
(2003)
Amino Acids
, vol.25
, pp. 249-257
-
-
Uchida, K.1
-
36
-
-
1642458415
-
Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity
-
J. Wang, G. Chen, M. Muckenthaler, B. Galy, M.W. Hentze, and K. Pantopoulos Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity Mol. Cell. Biol. 24 2004 954 965
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 954-965
-
-
Wang, J.1
Chen, G.2
Muckenthaler, M.3
Galy, B.4
Hentze, M.W.5
Pantopoulos, K.6
-
37
-
-
0035808315
-
Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase
-
C.C. Wei, Z.Q. Wang, Q. Wang, A.L. Meade, C. Hemann, R. Hille, and D.J. Stuehr Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase J. Biol. Chem. 276 2001 315 319
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 315-319
-
-
Wei, C.C.1
Wang, Z.Q.2
Wang, Q.3
Meade, A.L.4
Hemann, C.5
Hille, R.6
Stuehr, D.J.7
-
38
-
-
0037756787
-
Structure of a β-TrCP1-Skp1-β-catenin complex: Destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase
-
G. Wu, G. Xu, B.A. Schulman, P.D. Jeffrey, J.W. Harper, and N.P. Pavletich Structure of a β-TrCP1-Skp1-β-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase Mol. Cell 11 2003 1445 1456
-
(2003)
Mol. Cell
, vol.11
, pp. 1445-1456
-
-
Wu, G.1
Xu, G.2
Schulman, B.A.3
Jeffrey, P.D.4
Harper, J.W.5
Pavletich, N.P.6
-
39
-
-
0141989227
-
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
-
K. Yamanaka, H. Ishikawa, Y. Megumi, F. Tokunaga, M. Kanie, T.A. Rouault, I. Morishima, N. Minato, K. Ishimori, and K. Iwai Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2 Nat. Cell Biol. 5 2003 336 340
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 336-340
-
-
Yamanaka, K.1
Ishikawa, H.2
Megumi, Y.3
Tokunaga, F.4
Kanie, M.5
Rouault, T.A.6
Morishima, I.7
Minato, N.8
Ishimori, K.9
Iwai, K.10
-
40
-
-
0030731146
-
Inhibition of NF-κB cellular function via specific targeting of the IκB-ubiquitin ligase
-
A. Yaron, H. Gonen, I. Alkalay, A. Hatzubai, S. Jung, S. Beyth, F. Mercurio, A.M. Manning, A. Ciechanover, and Y. Ben-Neriah Inhibition of NF-κB cellular function via specific targeting of the IκB-ubiquitin ligase EMBO J. 16 1997 6486 6494
-
(1997)
EMBO J.
, vol.16
, pp. 6486-6494
-
-
Yaron, A.1
Gonen, H.2
Alkalay, I.3
Hatzubai, A.4
Jung, S.5
Beyth, S.6
Mercurio, F.7
Manning, A.M.8
Ciechanover, A.9
Ben-Neriah, Y.10
-
41
-
-
0028821439
-
Heme binds to a short sequence that serves a regulatory function in diverse proteins
-
L. Zhang, and L. Guarente Heme binds to a short sequence that serves a regulatory function in diverse proteins EMBO J. 14 1995 313 320
-
(1995)
EMBO J.
, vol.14
, pp. 313-320
-
-
Zhang, L.1
Guarente, L.2
|